PLCG2

gene product
The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3. [provided by RefSeq, Mar 2014]
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Antibodies

 

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Antibodypedia Validation Initiative

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  or   Clear
Enhanced validation
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Eligible for validation within AVI
979 antibodies from 37 providers.

Antibody properties

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AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
94 antibodies
Biorbyt
46 antibodies
Santa Cruz Biotechnology
1 antibody
antibodies-online
383 antibodies
GeneTex
19 antibodies
Bioworld Technology, Inc
7 antibodies
Abnova Corporation
13 antibodies
Atlas Antibodies
2 antibodies
Invitrogen Antibodies
17 antibodies
LifeSpan BioSciences, Inc.
63 antibodies
Cell Signaling Technology, Inc
4 antibodies
Aviva Systems Biology
12 antibodies
Affinity Biosciences
9 antibodies
Acris Antibodies GmbH
17 antibodies
St John's Laboratory
8 antibodies
NovoPro Bioscience Inc.
4 antibodies
Boster Biological Technology
2 antibodies
NSJ Bioreagents
1 antibody
OriGene
23 antibodies
Signalway Antibody LLC
5 antibodies
Arigo
6 antibodies
R&D Systems
3 antibodies
ProSci
4 antibodies
RabMAbs
16 antibodies
Abgent
8 antibodies
Abbkine Scientific Co.Ltd.
4 antibodies
United States Biological
112 antibodies