3871

antibody from Cell Signaling Technology, Inc

Targeting: PLCG2

Western blot (Data presented on provider website)

Antibody Data

Product number

3871

Provider

Cell Signaling Technology, Inc

Proper citation

Cell Signaling Technology Cat#3871, RRID:AB_2299548

Product name

Phospho-PLCγ2 (Tyr1217) Antibody

Antibody type

Polyclonal

Reactivity

Human, Mouse

Host

Rabbit

Storage

-20°C

References

Submitted references

Mast cell maturation is driven via a group III phospholipase A2-prostaglandin D2-DP1 receptor paracrine axis.

Taketomi Y, Ueno N, Kojima T, Sato H, Murase R, Yamamoto K, Tanaka S, Sakanaka M, Nakamura M, Nishito Y, Kawana M, Kambe N, Ikeda K, Taguchi R, Nakamizo S, Kabashima K, Gelb MH, Arita M, Yokomizo T, Nakamura M, Watanabe K, Hirai H, Nakamura M, Okayama Y, Ra C, Aritake K, Urade Y, Morimoto K, Sugimoto Y, Shimizu T, Narumiya S, Hara S, Murakami M
Nature immunology 2013 Jun;14(6):554-63

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SH2 domain-containing phosphatase-2 protein-tyrosine phosphatase promotes Fc epsilon RI-induced activation of Fyn and Erk pathways leading to TNF alpha release from bone marrow-derived mast cells.

McPherson VA, Sharma N, Everingham S, Smith J, Zhu HH, Feng GS, Craig AW
Journal of immunology (Baltimore, Md. : 1950) 2009 Oct 15;183(8):4940-7

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Basal B cell receptor-directed phosphatidylinositol 3-kinase signaling turns off RAGs and promotes B cell-positive selection.

Verkoczy L, Duong B, Skog P, Aït-Azzouzene D, Puri K, Vela JL, Nemazee D
Journal of immunology (Baltimore, Md. : 1950) 2007 May 15;178(10):6332-41