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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [4]
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- Product number
- ABIN362188 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Phospholipase C gamma 2 (PLCG2) (pTyr753) antibody
- Antibody type
- Polyclonal
- Antigen
- Peptide sequence around phosphorylation site of pTyr753 (S-L-Y (p) -D-V) derived from Human PLCg2. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
- Description
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- pTyr753
- Isotype
- IgG
- Vial size
- 100 μL
- Concentration
- 1 mg/mL
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Submitted references Tec kinases mediate sustained calcium influx via site-specific tyrosine phosphorylation of the phospholipase Cgamma Src homology 2-Src homology 3 linker.
Mechanism of B-cell receptor-induced phosphorylation and activation of phospholipase C-gamma2.
Glycoproteins VI and Ib-IX-V stimulate tyrosine phosphorylation of tyrosine kinase Syk and phospholipase Cgamma2 at distinct sites.
Requirements for distinct steps of phospholipase Cgamma2 regulation, membrane-raft-dependent targeting and subsequent enzyme activation in B-cell signalling.
Humphries LA, Dangelmaier C, Sommer K, Kipp K, Kato RM, Griffith N, Bakman I, Turk CW, Daniel JL, Rawlings DJ
The Journal of biological chemistry 2004 Sep 3;279(36):37651-61
The Journal of biological chemistry 2004 Sep 3;279(36):37651-61
Mechanism of B-cell receptor-induced phosphorylation and activation of phospholipase C-gamma2.
Kim YJ, Sekiya F, Poulin B, Bae YS, Rhee SG
Molecular and cellular biology 2004 Nov;24(22):9986-99
Molecular and cellular biology 2004 Nov;24(22):9986-99
Glycoproteins VI and Ib-IX-V stimulate tyrosine phosphorylation of tyrosine kinase Syk and phospholipase Cgamma2 at distinct sites.
Suzuki-Inoue K, Wilde JI, Andrews RK, Auger JM, Siraganian RP, Sekiya F, Rhee SG, Watson SP
The Biochemical journal 2004 Mar 15;378(Pt 3):1023-9
The Biochemical journal 2004 Mar 15;378(Pt 3):1023-9
Requirements for distinct steps of phospholipase Cgamma2 regulation, membrane-raft-dependent targeting and subsequent enzyme activation in B-cell signalling.
Rodriguez R, Matsuda M, Storey A, Katan M
The Biochemical journal 2003 Aug 15;374(Pt 1):269-80
The Biochemical journal 2003 Aug 15;374(Pt 1):269-80
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