ABIN362815

antibody from antibodies-online

Targeting: PLCG2

Western blot (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Antibody Data

Product number

ABIN362815

Provider

antibodies-online

Product name

anti-Phospholipase C gamma 2 (PLCG2) (AA 751-755) antibody

Antibody type

Polyclonal

Antigen

Peptide sequence around AA 751-755 (S-L-Y-D-V) derived from Human PLCg2. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Epitope

AA 751-755

Isotype

IgG

Vial size

50 μL

Concentration

1 mg/mL

Storage

Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

References

Submitted references

Tec kinases mediate sustained calcium influx via site-specific tyrosine phosphorylation of the phospholipase Cgamma Src homology 2-Src homology 3 linker.

Humphries LA, Dangelmaier C, Sommer K, Kipp K, Kato RM, Griffith N, Bakman I, Turk CW, Daniel JL, Rawlings DJ
The Journal of biological chemistry 2004 Sep 3;279(36):37651-61

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Mechanism of B-cell receptor-induced phosphorylation and activation of phospholipase C-gamma2.

Kim YJ, Sekiya F, Poulin B, Bae YS, Rhee SG
Molecular and cellular biology 2004 Nov;24(22):9986-99

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Glycoproteins VI and Ib-IX-V stimulate tyrosine phosphorylation of tyrosine kinase Syk and phospholipase Cgamma2 at distinct sites.

Suzuki-Inoue K, Wilde JI, Andrews RK, Auger JM, Siraganian RP, Sekiya F, Rhee SG, Watson SP
The Biochemical journal 2004 Mar 15;378(Pt 3):1023-9

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Requirements for distinct steps of phospholipase Cgamma2 regulation, membrane-raft-dependent targeting and subsequent enzyme activation in B-cell signalling.

Rodriguez R, Matsuda M, Storey A, Katan M
The Biochemical journal 2003 Aug 15;374(Pt 1):269-80