ABIN319402

antibody from antibodies-online

Targeting: PLCG2

Immunocytochemistry (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN319402

Provider

antibodies-online

Product name

anti-Phospholipase C gamma 2 (PLCG2) (Tyr1217) antibody

Antibody type

Polyclonal

Description

Immunoaffinity Chromatography

Reactivity

Human, Mouse, Rat

Host

Rabbit

Epitope

Tyr1217

Vial size

50 μL

Storage

Store the antibody (in aliquots) at-20°C.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

Four tyrosine residues in phospholipase C-gamma 2, identified as Btk-dependent phosphorylation sites, are required for B cell antigen receptor-coupled calcium signaling.

Watanabe D, Hashimoto S, Ishiai M, Matsushita M, Baba Y, Kishimoto T, Kurosaki T, Tsukada S
The Journal of biological chemistry 2001 Oct 19;276(42):38595-601

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Molecular mechanism of the inhibition of phospholipase C beta 3 by protein kinase C.

Yue C, Ku CY, Liu M, Simon MI, Sanborn BM
The Journal of biological chemistry 2000 Sep 29;275(39):30220-5

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Regulation of eukaryotic phosphatidylinositol-specific phospholipase C and phospholipase D.

Singer WD, Brown HA, Sternweis PC
Annual review of biochemistry 1997;66:475-509

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Regulation of polyphosphoinositide-specific phospholipase C activity by purified Gq.

Smrcka AV, Hepler JR, Brown KO, Sternweis PC
Science (New York, N.Y.) 1991 Feb 15;251(4995):804-7