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Flow cytometryAntibody data
- Antibody Data
- Antigen structure
- References [12]
- Comments [0]
- Validations
- Flow cytometry [2]
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- Product number
- MA1-10295 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- CD86 Monoclonal Antibody (BU63), FITC
- Antibody type
- Monoclonal
- Antigen
- Other
- Description
- This antibody reacts with an extracellular epitope of CD86 (B7-2), a 70 kDa type I transmembrane glycoprotein of immunoglobulin supergene family, expressed on professional antigen-presenting cells, such as dendritic cells, macrophages or activated B lymphocytes.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Green dye
- Isotype
- IgG
- Antibody clone number
- BU63
- Vial size
- 100 Tests
- Storage
- 4° C, store in dark, DO NOT FREEZE!
Submitted references Major histocompatibility complex class II (DR) antigen and costimulatory molecules on in vitro and in vivo activated human polymorphonuclear neutrophils.
Profiling dendritic cell maturation with dedicated microarrays.
Cross-talk between activated human NK cells and CD4+ T cells via OX40-OX40 ligand interactions.
Cross-talk between activated human NK cells and CD4+ T cells via OX40-OX40 ligand interactions.
Susceptibility of immature and mature Langerhans cell-type dendritic cells to infection and immunomodulation by human cytomegalovirus.
Susceptibility of immature and mature Langerhans cell-type dendritic cells to infection and immunomodulation by human cytomegalovirus.
CD80 and CD86 C domains play an important role in receptor binding and co-stimulatory properties.
CD80 and CD86 C domains play an important role in receptor binding and co-stimulatory properties.
Commitment of juvenile myelo-monocytic (JMML) leukemic cells to spontaneously differentiate into dendritic cells.
CD40 ligand-stimulated B cell precursor leukemic cells elicit interferon-gamma production by autologous bone marrow T cells in childhood acute lymphoblastic leukemia.
Human CD4(+)CD25(+) cells: a naturally occurring population of regulatory T cells.
Human CD4(+)CD25(+) cells: a naturally occurring population of regulatory T cells.
Sandilands GP, McCrae J, Hill K, Perry M, Baxter D
Immunology 2006 Dec;119(4):562-71
Immunology 2006 Dec;119(4):562-71
Profiling dendritic cell maturation with dedicated microarrays.
McIlroy D, Tanguy-Royer S, Le Meur N, Guisle I, Royer PJ, Léger J, Meflah K, Grégoire M
Journal of leukocyte biology 2005 Sep;78(3):794-803
Journal of leukocyte biology 2005 Sep;78(3):794-803
Cross-talk between activated human NK cells and CD4+ T cells via OX40-OX40 ligand interactions.
Zingoni A, Sornasse T, Cocks BG, Tanaka Y, Santoni A, Lanier LL
Journal of immunology (Baltimore, Md. : 1950) 2004 Sep 15;173(6):3716-24
Journal of immunology (Baltimore, Md. : 1950) 2004 Sep 15;173(6):3716-24
Cross-talk between activated human NK cells and CD4+ T cells via OX40-OX40 ligand interactions.
Zingoni A, Sornasse T, Cocks BG, Tanaka Y, Santoni A, Lanier LL
Journal of immunology (Baltimore, Md. : 1950) 2004 Sep 15;173(6):3716-24
Journal of immunology (Baltimore, Md. : 1950) 2004 Sep 15;173(6):3716-24
Susceptibility of immature and mature Langerhans cell-type dendritic cells to infection and immunomodulation by human cytomegalovirus.
Hertel L, Lacaille VG, Strobl H, Mellins ED, Mocarski ES
Journal of virology 2003 Jul;77(13):7563-74
Journal of virology 2003 Jul;77(13):7563-74
Susceptibility of immature and mature Langerhans cell-type dendritic cells to infection and immunomodulation by human cytomegalovirus.
Hertel L, Lacaille VG, Strobl H, Mellins ED, Mocarski ES
Journal of virology 2003 Jul;77(13):7563-74
Journal of virology 2003 Jul;77(13):7563-74
CD80 and CD86 C domains play an important role in receptor binding and co-stimulatory properties.
Vasu C, Wang A, Gorla SR, Kaithamana S, Prabhakar BS, Holterman MJ
International immunology 2003 Feb;15(2):167-75
International immunology 2003 Feb;15(2):167-75
CD80 and CD86 C domains play an important role in receptor binding and co-stimulatory properties.
Vasu C, Wang A, Gorla SR, Kaithamana S, Prabhakar BS, Holterman MJ
International immunology 2003 Feb;15(2):167-75
International immunology 2003 Feb;15(2):167-75
Commitment of juvenile myelo-monocytic (JMML) leukemic cells to spontaneously differentiate into dendritic cells.
Longoni D, D'Amico G, Gaipa G, Bernasconi S, Vulcano M, Onnis P, Niemeyer CM, Allavena P, Biondi A
The hematology journal : the official journal of the European Haematology Association 2002;3(6):302-10
The hematology journal : the official journal of the European Haematology Association 2002;3(6):302-10
CD40 ligand-stimulated B cell precursor leukemic cells elicit interferon-gamma production by autologous bone marrow T cells in childhood acute lymphoblastic leukemia.
Todisco E, Gaipa G, Biagi E, Bonamino M, Gramigna R, Introna M, Biondi A
Leukemia 2002 Oct;16(10):2046-54
Leukemia 2002 Oct;16(10):2046-54
Human CD4(+)CD25(+) cells: a naturally occurring population of regulatory T cells.
Ng WF, Duggan PJ, Ponchel F, Matarese G, Lombardi G, Edwards AD, Isaacs JD, Lechler RI
Blood 2001 Nov 1;98(9):2736-44
Blood 2001 Nov 1;98(9):2736-44
Human CD4(+)CD25(+) cells: a naturally occurring population of regulatory T cells.
Ng WF, Duggan PJ, Ponchel F, Matarese G, Lombardi G, Edwards AD, Isaacs JD, Lechler RI
Blood 2001 Nov 1;98(9):2736-44
Blood 2001 Nov 1;98(9):2736-44
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD86 (BU63) FITC Monoclonal antibody (Product # MA1-10295) using a dilution of 20 µL reagent/100 µL of peripheral whole blood.
- Conjugate
- Green dye
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Separation of human monocytes (red-filled) from CD86 negative lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD86 (BU63) FITC Monoclonal antibody (Product # MA1-10295) using a dilution of 20 µL reagent/100 µL of peripheral whole blood.
- Conjugate
- Green dye
