Tissue expression
Cell line expression

CD86

gene product
B7-2, B7.2, CD28LG2 
This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, May 2011]
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AntibodyRefsTypeWBELICCIPIHCFC
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Bioss
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EMD Millipore
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GenWay
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eBioscience, An Affymetrix Company
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Exalpha Biologicals, Inc.
1 antibody
MilliporeSigma / Merck KGaA
3 antibodies
Rockland Immunochemicals, Inc.
5 antibodies