HY-P83710m

antibody from MedChemExpress LLC

Targeting: CD86 B7-2, B7.2, CD28LG2

No application information provided.

Antibody Data

Product number

HY-P83710m

Provider

MedChemExpress LLC

Product name

Rat Anti-Mouse CD86 Antibody (FITC)

Antibody type

Monoclonal

Description

CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is a ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce co-stimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

Reactivity

Mouse

Host

Mouse

Storage

Stored at 2-8¡ãC for 1 year, protect from light, do not freeze.