Antibody data
- Antibody Data
- Antigen structure
- References [423]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- 13395-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13395-1-AP, RRID:AB_2074882
- Product name
- CD86 antibody
- Antibody type
- Polyclonal
- Description
- CD86 antibody (Cat. #13395-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, rat and has been validated for the following applications: FC, IF, WB, ELISA.
- Reactivity
- Human, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
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After Traumatic Brain Injury, EPHA4 Enhances Endoplasmic Reticulum Stress to Promote M1 Microglial Polarization Through the MAPK Signaling Pathway.
Microglial TIA1-mediated stress granules promote neuroinflammation and aggravate neuron loss in mice after ischemic stroke by inhibiting IGF2 signaling.
Dissolvable microneedles loaded with denosumab alleviate knee osteoarthritis in rodent and canine models by inhibiting macrophage senescence.
Influence of micro- and nanoscale cues on immune factors secretion: implications for immunomodulation.
A near-infrared regulated programmable multi-mode periosteum scaffold for sequential healing of infected bone defects.
Aspirin-induced mesenchymal stem cell-derived extracellular vesicles promote osteochondral regeneration by reprogramming macrophages.
Pomegranate-inspired bionic microgel/periosteum composite harnessing reactive oxygen species for immune-engineered bone regeneration.
Huangtu Decoction regulates macrophage M1/M2 polarization to alleviate DSS- and rhubarb-induced Deficiency-Cold Pattern in Ulcerative Colitis by inhibiting the HIF-1α signaling pathway.
Immune regulative GelMA&Zn(2+)/Ce(3+)-whitlockite scaffolds with continuous ions release for bone regeneration.
Dual functional properties of a probiotic biofilm-decorated bone substitute to combat infection and promote osteoimmunomodulation.
Engineering multifunctional microspheres for sequential regulation of osteoimmune microenvironment and bone remodeling balance to promote regeneration of osteoporotic bone defects.
NLRP3 Mediates Submandibular Gland Regeneration in Duct Ligation/De-Ligation Model.
M2 macrophage-derived exosome nanoplatform for targeted H(2)S delivery to alleviate hepatic ischemia-reperfusion injury via synergistic anti-oxidative, anti-inflammatory, and anti-ferroptotic effects.
An Injectable Thermosensitive Hydrogel Codelivering Permeability-Promoting Nintedanib-loaded Phase-transition Nanoparticles and Doxorubicin to Potentiate Immunogenic Cell Death in Triple-Negative Breast Cancer for Chemoimmunotherapy.
ZXDB Drives Macrophage Inflammatory Programming in Sepsis-Induced Acute Kidney Injury by Recruiting EIF4A3 to Enhance ACACA Translation.
Tailored Porous Bimetallic Nanozyme Platform for Full-Cycle Therapeutics of Intestinal Ischemia/Reperfusion.
Microglial PRMT2IP alleviates ischemia-induced brain injury.
A core-shell microneedle platform for the spatiotemporal codelivery of dual-agent therapeutics precisely orchestrates diabetic wound healing.
Cornuside alleviates microglia-mediated neuroinflammation to ameliorate chronic neuropathic pain-induced cognitive impairment via the Nrf2/Sirt3 signaling pathway.
AICAR improves depression-like behaviors and is associated with hippocampal AMPK activation and modulation of neurogenesis and neuroinflammation in a microbiota disruption model.
Network pharmacology-guided self-assembling quercetin hydrogel from Astragalus membranaceous accelerates diabetic wound healing.
Intermittent fasting attenuates ovarian chronic inflammation in obese mice by inhibiting the CXCL12-CXCR4 axis.
Diallyl Trisulfide Suppresses Tumor-Associated Macrophage M2-Like Polarization and Recruitment and Improves the Tumor Microenvironment Through Blocking CCL5/STAT3 Signaling Pathway Against Lung Cancer.
Polydopamine nanoparticle-enhanced stem cell spheroid-derived decellularized extracellular matrix with antioxidant and tissue-adhesive properties for brain repair.
MCU knockdown mitigates post-stroke neuroinflammation through SLC33A1-mediated reduction of NR4A1 acetylation.
Salidroside ameliorates experimental autoimmune neuritis by dually modulating neuroinflammation and immune homeostasis via PI3K/AKT signaling.
Coxsackievirus B3 regulates macrophage polarization through ANXA3 to promote the development of myocarditis.
USP11-PGAM5 Axis Promotes Neurotoxic Astrocyte Reactivity by Aggravating the mtDNA-cGAS-STING Pathway After Intracerebral Hemorrhage.
Hyaluronan of Different Molecular Weights Exerts Distinct Therapeutic Effects on Bleomycin-Induced Acute Respiratory Distress Syndrome.
Single-cell transcriptomics uncover RNF130-mediated TNF-α pathway activation and worenine synergy with paclitaxel in breast cancer.
Caveolin-2 Knockdown Alleviated Sepsis-induced Acute Lung Injury Via Promoting Macrophage M2 Polarization and Inhibiting Apoptosis by Hippo Signaling Pathway.
Explore the chemical components of Angong Niuhuang Pill and its potential mechanisms for fever treatment based on UHPLC-Q-Exactive orbitrap HRMS, transcriptomics, and experiment verification.
Mechanistic insights into the effects of Norisoboldine on intestinal immunity and neuroinflammation in a mouse model of slow transit constipation with depression.
β-Aminoisobutyric acid targets AMPK to suppress macrophage pro-inflammatory phenotype and alleviate lipopolysaccharide-induced sepsis in mice.
Effect and Mechanism of Apoptotic Bodies from Inflammatory Periodontal Ligament Stem Cells on Macrophage M1 Polarisation.
Genistein Ameliorates the Ischemic State of Random Skin Flap by Regulating Macrophage Polarization Through AMPK/SIRT1 Signaling Pathway.
Self-regulating neohesperidin/silk fibroin composite aerogel for enhanced wound healing via pH-responsive release.
Programmed temporal modulation by using a magnetoelectric wound dressing for ultra-fast early-stage wound healing.
Blastocyst Structure-Inspired Core-Shell Stem Cell Microspheres with Hyperoside Delivery for Endometrial Regeneration.
A Biomimetic Norepinephrine-Loaded Aligned Mineralized Collagen Scaffold for Coordinated Neurovascular, Osteogenic, and Immunomodulatory Repair of Critical-Sized Bone Defects.
Kaempferol Alleviates Glucocorticoid-Induced Osteonecrosis of the Femoral Head by Modulating Macrophage M1/M2 Polarization Through RhoA/ROCK-Mediated Mitophagy Activation.
ICAM2 loss drives 5-fluorouracil resistance via TGF-β/Smad/SP1/PTN-dependent apoptosis evasion and macrophage remodeling in gastric cancer.
A dual-action nanoparticle approach for spinal cord injury treatment: ferroptosis inhibition, inflammation control, and Myelin preservation.
Hypoxia-preconditioned cardiomyocyte-derived extracellular vesicles alleviate myocardial ischemic injury by reprogramming macrophage polarization via the Fgl2/NF-κB pathway.
Synergism of microgrooves and gallium phytate coating on PEKK based percutaneous implant with photothermal effect facilitates biological sealing of skin tissue for combating infection.
Mossy-textured hydroxyapatite-modified poly (lactic-co-glycolic acid) microspheres promote collagen regeneration via calcium/TGF-β and chemokine signaling pathways in soft tissue augmentation.
Tirzepatide mitigates atherosclerosis progression and modulates oxLDL-mediated proatherogenic effects in macrophages: evidence for M1/M2 homeostasis restoration.
HMGA2 promotes hepatocellular carcinoma progression by regulating tumor-associated macrophage via Notch1/CCL2 signaling.
Core fucosylation of NCEH1 by FUT8 promotes progression of high-grade serous ovarian cancer by driving tumor-associated macrophage M2 polarization.
3D-printed titanium scaffolds coated with a multifunctional photothermal-responsive hydrogel promote osteoporotic bone defect repair.
Wine-Processed Cornus officinalis Ameliorates Osteoarthritis via Modulating M1/M2 Macrophage Polarization.
Senescence-Driven Remodeling Defines an Aggressive and Immunomodulatory Subtype of Endometriosis.
RUVBL2 Regulates Microglia Metabolic Reprogramming to Mediate Stress Granules Aggregation Exacerbating Postoperative Delirium in Aged Mild Cognitive Impairment Rats.
Cancer Cell-Intrinsic Cholesterol Induces Lipid-Associated Macrophage Differentiation via SP1 Palmitoylation to Promote Prostate Cancer Progression.
Integrative analysis and experimental validation unveil TNFSF10 as a key PANoptosis inducer driving preeclampsia pathogenesis.
Altered Atlas of Exercise-Responsive MicroRNAs Revealing miR-29a-3p Attacks Armored and Cold Tumors and Boosts Anti-B7-H3 Therapy.
A Mesoporous Silica-Based Naringenin Delivery System Promoting Macrophage M2 Polarization in Atherosclerosis.
Hyperuricemia in ob/ob mice relates to hepatocellular pyruvate metabolism/ xanthine oxidase axis.
Prussian Blue Nanoparticle-Induced Alteration of the Polarization State of Tumor-Associated Macrophages as a Substantial Antitumor Mechanism Against Oral Squamous Cell Carcinoma (OSCC).
The Human Milk-derived Peptide Drives Rapid Regulation of Macrophage Inflammation Responses in the Neonatal Intestine.
Exploring the Therapeutic Mechanism of Jianpi Zhidong Decoction on Tourette Syndrome Based on Proteomics and Network Pharmacology.
TENS alleviates CP/CPPS-related inflammation and pain by modulating Kir2.1-dependent macrophage polarization.
Reciprocal activation between M1 macrophages and trophoblasts through CXCL9/STAT1/ZEB1/CCL2 axis promotes recurrent spontaneous abortion.
Stat3-mediated Th17 pathogenicity induced by periodontitis contributes to cognitive impairment by promoting microglial M1 polarization.
Wharton's jelly-derived mesenchymal stem cells ameliorate high altitude-induced heart injury by promoting type 2 macrophage polarization via COX2-PGE2 pathway.
Berbamine attenuates hind limb ischemia-reperfusion injury by eliminating lipid ROS and inhibiting p65 nuclear translocation.
Ultra-small quercetin-based nanotherapeutics ameliorate acute liver failure by combatting inflammation/cellular senescence cycle.
Hsa_circ_0058495-mediated IGF2BP2 ubiquitination and m6A modification of MEKK1 promote the progression of PDAC.
Tremella fuciformis Polysaccharides Alleviate Early Brain Injury in Experimental Subarachnoid Hemorrhage by Inhibiting the KDR-Mediated P38 MAPK/NF-κB Pathway.
Combining transcriptomics and network pharmacology to reveal the mechanisms of QuZhuoHuaYu decoction ameliorating gouty arthritis.
A Myelin Debris Cleaner for Spinal Cord Injury Recovery: Polycaprolactone / Cell Membrane Assembled Scaffolds.
METTL14 knockdown augmented the polarization of M2-like macrophages to promote acute myeloid leukemia progression.
Lactobacillus acidophilus promotes cognitive function recovery via regulating microglial peroxisomal function in cerebral ischemia.
Gut microbiota diversity and metabolomics analysis of curcumin's alleviation of abdominal aortic aneurysm progression.
Engineered decellularized tendon hydrogel with sustained zinc ion release orchestrates anti-inflammatory microenvironment and functional regeneration in Achilles tendinopathy.
Columbianadin targets TRIM7 to maintain P2X7 palmitoylation, inhibiting cuproptosis in synovial M2 macrophages.
POSTN-Mediated Interplay of M1 Polarized Macrophage with Tendon-Derived Stem Cells to Drive Traumatic Heterotopic Ossification Formation through PTK7/ATK Signaling?
Intratumoral microbiota-driven macrophage reprogramming in pancreatic cancer via Blautia metabolite 6-hydroxyhexanoic acid.
Ershen Dan attenuates atherosclerosis by modulating the NOTCH1/NF-κB/NLRP3 signaling pathway to suppress M1 macrophage polarization.
Microglia-Derived Exosomal miR-223-3p Targets the RhoB-NF-κB-CCL11 Axis in Astrocytes and Relieves Neuronal Damage in Subarachnoid Hemorrhage.
ALKBH8-mediated codon-specific translation promotes colorectal tumorigenesis.
Fe-MOF loaded with capmatinib to reverse immunosuppressive microenvironment and inhibit tumor metastasis after radiofrequency ablation.
The Crosstalk Between Sepsis-Associated Encephalopathy and Alzheimer's Disease: Identifying Potential Biomarkers and Therapeutic Targets for Cognition.
An aptamer specifically targeting mCRP ameliorates experimental arthritis.
(20S)-protopanaxatriol attenuates Ang II-induced renal injury via PTPN1-mediated AMPK/mTOR signaling pathway.
Sinomenine alleviates gouty inflammation by inhibiting macrophage M1 polarization and neutrophil extracellular trap formation.
Treadmill exercise alleviates STING-mediated microglia pyroptosis and polarization via activating mitophagy post-TBI.
Decoupling Half-Process Assisted Mitochondrial Transplantation via Self-Stripping pHLIP Boosts Macrophages Reprogramming for Inflammation Resolution.
AMPK upregulates SOCS1 to promote TFEB nuclear transfer, enhances autophagy, inhibits macrophage M1 polarization and relieves acute lung injury.
Inhibition of Macrophage ARID3A Alleviates Myocardial Ischemia-Reperfusion Injury After Heart Transplantation by Reducing THBS1/CD47 Signaling-Mediated Neutrophil Extracellular Traps Formation.
Sleep Deprivation Aggravates Periodontitis Through Trigeminal-Periodontal Neuroimmune Pathway Mediated by the AChE-ACh-α7nAChR Axis.
Fatty acid-binding protein 4 drives microglia-mediated neuroinflammation through promoting S100A9 expression and lipid droplet accumulation after intracerebral hemorrhage.
Oral Multi-Enzymatic Manganese-Carbon Dots Alleviate Sepsis-Associated Lung Injury via the Gut-Lung Axis.
Urolithin B promotes the functional recovery of spinal cord injury by alleviating neuroinflammation via the inhibition of NLRP3 signaling pathway.
11-keto-β-boswellic acid and Z-guggulsterone suppress HMGB1/TLR4 pathway activity and modulate microglial polarization to remodel perineuronal nets after nerve injury.
Application of Dental Pulp Stem Cell-Derived Intracellular Vesicles for Diabetic Wound Healing.
FGF21-loaded M2 macrophage-derived exosomes attenuate sepsis-induced lung injury by regulating M2 macrophage polarization and glycolysis.
Th22 cells promote the transition from homeostatic to reactive microglia in diabetic encephalopathy.
An ultrasound-driven PLGA/Zn-KNN hybrid piezoelectric scaffold with direct and immunoregulatory antibacterial activity for bone infection.
Restoring tendon microenvironment in tendinopathy: Macrophage modulation and tendon regeneration with injectable tendon hydrogel and tendon-derived stem cells exosomes.
Three polysaccharides from Roughhaired Holly Root with immune-enhancing activity via activation of TLR receptor.
Electroacupuncture alleviates diesel exhaust particles-induced inflammatory response in lung through dopamine inhibition of NLRP3 signaling pathway.
Mg(2+)-Loaded Black Phosphorus Nanosheet Protects against Cerebral Ischemic Injury through Anti-Oxidative and Anti-Inflammatory Effects.
GTS-21 alleviates sepsis-induced atrial fibrillation susceptibility by modulating macrophage polarization and Neuregulin-1 secretion.
L-Kynurenine regulates immune response in ICIs-associated myocarditis via JAK/STAT pathway.
Astragaloside IV prevents liver fibrosis by blocking glycolysis-mediated macrophage M1 polarization.
Microneedle-mediated hypoxic extracellular vesicle-encapsulated selenium nanoparticles delivery to treat androgenetic alopecia.
Response to: Correspondence on 'Unveiling inflammatory and prehypertrophic cell populations as key contributors to knee cartilage degeneration in osteoarthritis using multi-omics data integration' by Fan et al.
An active shrinkage and antioxidative hydrogel with biomimetic mechanics functions modulates inflammation and fibrosis to promote skin regeneration.
Trimethylamine N-oxide aggravates human aortic valve interstitial cell inflammation by regulating the macrophages polarization through a N6-methyladenosine-mediated pathway.
A kidney protection nanoparticle based on Alpinia oxyphylla fructus polysaccharide by modulating macrophage polarization.
Rapid angiogenic hydrogel nanofiber scaffold promotes random flap regeneration and modulates inflammation.
M2 macrophages promote PKM2 production in fibroblasts to alleviate UVB-induced photoaging.
Janus hydrogel microrobots with bioactive ions for the regeneration of tendon-bone interface.
Tremella polysaccharide microneedles loaded with magnetic dental pulp stem cell intracellular vesicles used for androgenic alopecia.
The role of Morin in attenuating atherosclerosis via STAT1 pathway inhibition.
Corilagin enhances wound healing by modulating the macrophage phenotype in diabetic mice.
Topical transdermal administration of lenalidomide nanosuspensions-based hydrogels against melanoma: In vitro and in vivo studies.
A novel strategy for bone defect repair: Stromal cell-derived factor 1α sustained-release acellular fish scale scaffolds combined with injection of bone marrow mesenchymal stem cells promote bone regeneration.
CuATSM Enhances Wound Repair Without Scarring via Hippo/YAP Signalling Pathway to Reduce Ferroptosis and Macrophage Polarisation.
Ultraviolet-treated riboflavin alleviates atopic dermatitis by inhibiting NLRP3 inflammasome activation and M1 macrophage polarization via histone lactylation.
Ultrasound-responsive taurine lipid nanoparticles attenuate oxidative stress and promote macrophage polarization for diabetic wound healing.
TREM2 activation reduces white matter injury via PI3K/Akt/GSK-3β signalling after intracerebral haemorrhage.
Gallic acid promotes M2 macrophage polarization through mitochondrial oxidative phosphorylation in periodontitis.
The microglial state transition as a novel mechanism by which fresh Baihe Dihuang decoction prevents depression by regulating SIRT1/HMGB1 signaling.
An Intelligent and Conductive Hydrogel with Multiresponsive and ROS Scavenging Properties for Infection Prevention and Anti-Inflammatory Treatment Assisted by Electrical Stimulation for Diabetic Wound.
PINK1 affects mitochondrial oxidative phosphorylation by regulating MFN2 to alleviate diabetic kidney disease.
Exercise-induced irisin ameliorates cognitive impairment following chronic cerebral hypoperfusion by suppressing neuroinflammation and hippocampal neuronal apoptosis.
miR-29a nanoparticles improve chronic insomnia by regulating microglia activation and hippocampal neuronal cell pyroptosis through PER2/NF-κB axis.
Integrative PANoptosis gene profiling reveals prognostic and therapeutic insights in prostate cancer.
Tumor-derived exosomal miR-425-5p and miR-135b-3p enhance colorectal cancer progression through immune suppression and vascular permeability promotion.
Cannabinoid Receptor-2 Alleviates Sepsis-Induced Neuroinflammation by Modulating Microglia M1/M2 Subset Polarization Through Inhibiting Nogo-B Expression.
The Polarization of Macrophages Regulated by KCNG3 via the Activation of ASK1 Mediated by Potassium Ion Efflux.
Hyaluronic acid methacryloyl hydrogel with sustained IL-10 release promotes macrophage M2 polarization and motor function after spinal cord injury.
Akkermansia muciniphila relieves inflammatory response in DSS-induced ulcerative colitis in mice through regulating macrophage polarization via SCFAs-SLC52A2/FFAR2 pathway.
Photosensitive Biomimetic Nanomedicine-Mediated Recombination of Adipose Microenvironments for Antiobesity Therapy.
DPSCs modulate synovial macrophage polarization and efferocytosis via PINK1/Parkin-dependent mitophagy.
Colchicine alleviates ischemic white matter lesions and cognitive deficits by inhibiting microglia inflammation via the TAK1/MAPK/NF-κB signaling pathway.
Wenxia Changfu formula inhibits Lewis lung cancer metastasis by reprogramming tumor-associated macrophages through the PPAR-γ/CD36 pathway.
Author Correction: Fibroblast derived C3 promotes the progression of experimental periodontitis through macrophage M1 polarization and osteoclast differentiation.
Activation of Hippocampal ACE2 Prevents the Dysbiosis-induced Depression-like Behavior in Mice by Enhanced Neurogenesis and Neuroprotection via Mas Receptor.
Agrocybe cylindracea Polysaccharides Ameliorate DSS-Induced Colitis by Restoring Intestinal Barrier Function and Reprogramming Immune Homeostasis via the Gut-Liver Axis.
Poldip2 Aggravates inflammation in diabetic retinopathy by impairing mitophagy via the AMPK/ULK1/Pink1 pathway.
Spi1 aggravates neuropathic pain by modulating Clec7a-mediated neuroinflammation and microglial phagocytosis.
Multilayered hydrogel scaffold construct with native tissue matched elastic modulus: A regenerative microenvironment for urethral scar-free healing.
Carboxymethylated yeast β-glucan: Biological activity screening in zebrafish, sprayable hydrogel preparation, and wound healing study in diabetic mice.
The Anti-Inflammatory Effects of Formononetin, an Active Constituent of Pueraria montana Var. Lobata, via Modulation of Macrophage Autophagy and Polarization.
Sodium butyrate regulates macrophage polarization by TGR5/β-arrestin2 in vitro.
Extracellular Matrix-Mimicking Hydrogel with Angiogenic and Immunomodulatory Properties Accelerates Healing of Diabetic Wounds by Promoting Autophagy.
sB7-H4 is a diagnostic biomarker in epithelial ovarian cancer and correlates to platinum resistance.
Mesoporous Prussian blue nanoparticle neuroconduit for the biological therapy targeting oxidative stress reduction, inflammation inhibition, and nerve regeneration.
Zinc-induced photocrosslinked konjac glucomannan/glycyrrhizic acid hydrogel promotes skin wound healing in diabetic mice through immune regulation.
ALKBH5 alleviates lower extremity arteriosclerosis by regulating ITGB1 demethylation and influencing macrophage polarization.
PTX3 impairs granulosa cell function by promoting the secretion of inflammatory cytokines in M1 macrophages via the JAK pathway.
Coptisine improves LPS-induced anxiety-like behaviors by regulating the Warburg effect in microglia via PKM2.
Manipulation of Surface Potential Distribution Enhances Osteogenesis by Promoting Pro-Angiogenic Macrophage Polarization via Activation of the PI3K-Akt Signaling Pathway.
Hydroxysafflor yellow A attenuates the inflammatory response in cerebral ischemia-reperfusion injured mice by regulating microglia polarization per SIRT1-mediated HMGB1/NF-κB signaling pathway.
Blocking the CCL5/CCL7-CCR1 axis regulates macrophage polarization through NF-κB pathway to alleviate the progression of osteoarthritis.
hBMSC-EVs alleviate weightlessness-induced skeletal muscle atrophy by suppressing oxidative stress and inflammation.
Hepatic Abnormal Secretion of Apolipoprotein C3 Promotes Inflammation in Aortic Dissection.
LDHA-mediated glycolysis in stria vascularis endothelial cells regulates macrophages function through CX3CL1-CX3CR1 pathway in noise-induced oxidative stress.
ITIH5-mediated fibroblast/macrophage crosstalk exacerbates cardiac remodelling after myocardial infarction.
Exosomes from adipose-derived stem cells accelerate wound healing by increasing the release of IL-33 from macrophages.
Dapagliflozin alleviated seizures and cognition impairment in pilocarpine induced status epilepticus via suppressing microglia-mediated neuroinflammation and oxidative stress.
Intelligent sequential degradation hydrogels by releasing bimetal-phenolic for enhanced diabetic wound healing.
Bulk and Single-cell transcriptomic profiling identifies C1QA as an Immune-Associated hub genes in graves' ophthalmopathy.
ACOD1/Itaconate regulates trophoblast function through the PI3K/Akt/FOLR1 axis to participate in the pathogenesis of recurrent spontaneous abortion.
A study on the establishment of a traumatic brain injury model of tree shrews and the observation of neuroinflammatory responses.
Synthesis and evaluation of lansiumamide B analogues to ameliorate acute lung injury by reducing oxidative stress and inflammation via Keap1/Nrf2/NF-κB pathway.
(R)-Bambuterol attenuates DSS-induced chronic colitis by suppressing inflammation, repairing intestinal barrier, and modulating gut microbiota and serum metabolomic profile.
The Role of Chaf1b in Maintaining Glioma Stem Cell Stemness and Regulating Microglial Polarization.
Trained immunity attenuated acute lung injury by activating alveolar macrophages via AKT2-PDK1 axis-mediated metabolic reprogramming.
Denosumab attenuates knee osteoarthritis progression by inhibiting synovial inflammation via the RANK/TRAF6/FSTL1 signalling.
Antigen B from Echinococcus granulosus regulates autophagy-mediated macrophage polarization to alleviate immune thrombocytopenia.
Fennel essential oil and its nanoemulsion modulate macrophage-mediated inflammatory responses and promote pressure ulcer healing.
Pathology-inspired collagen-binding thermosensitive micelle drops enable prolonged and efficient treatment of fungal keratitis.
Synergistic microglial modulation by laminarin-based platinum nanozymes for potential intracerebral hemorrhage therapy.
Mechanically-adaptive Janus hydrogel enhances scarless tendon healing with tissue-adhesion prevention.
MDL800, a SIRT6 activator, mitigates neuroinflammation-induced retinal damage by modulating microglial M1/M2 polarization in experimental glaucoma.
COG1410 Alleviated Chronic Sleep Deprivation-Induced Memory Loss by Regulating Microglial Phagocytosis and Inhibiting Hippocampal Inflammation.
Exosomal miR-218 secreted from endothelial progenitor cells mitigates acute lung injury in sepsis mice by inhibiting HMGA1 in alveolar macrophages.
Growth differentiation factor 11 attenuates sepsis-associated acute kidney injury by reducing inflammation and coagulation via PGC-1α/Nrf2 activation.
Targeting Irgm1 to combat osteoporosis: suppressing ROS and restoring bone remodeling.
KLF11 alleviates rheumatoid arthritis by regulating M1 macrophage polarization via downregulation of YAP1 expression.
FGF21 Alleviates Hypoxic-Ischemic White Matter Injury in Neonatal Mice by Mediating Inflammation and Oxidative Stress Through PPAR-γ Signaling Pathway.
Eliminating Radioresistance With a Magnetic Ion-Generator by Simultaneously Augmenting DNA Damage and Diminishing Immunosuppression.
Implantation of MSC spheroid-derived 3D decellularized ECM enriched with the MSC secretome ameliorates traumatic brain injury and promotes brain repair.
An injectable and adaptable system for the sustained release of hydrogen sulfide for targeted diabetic wound therapy by improving the microenvironment of inflammation regulation and angiogenesis.
Dendritic Cell Derived-Extracellular Vesicles Engineered to Express Interleukin-12 and Anti-CTLA-4 on Their Surface for Combinational Cancer Immunotherapy.
S-propargyl-cysteine attenuates temporomandibular joint osteoarthritis by regulating macrophage polarization via Inhibition of JAK/STAT signaling.
Platycodon grandiflorum exosome-like nanoparticles: the material basis of fresh platycodon grandiflorum optimality and its mechanism in regulating acute lung injury.
Silybin attenuates microglia-mediated neuroinflammation via inhibition of STING in experimental subarachnoid hemorrhage.
A Visible-Light Photocatalysis/Hydrolysis Hydrogen-Generating Nanoplatform for Dynamic Inflammation Management via Immune Metabolism Orchestration during Wound Repair.
Polydopamine-functionalized acellular fish scale scaffolds for accelerated bone tissue regeneration.
Y4 RNA fragment alleviates myocardial injury in heart transplantation via SNRNP200 to enhance IL-10 mRNA splicing.
Fibroblast derived C3 promotes the progression of experimental periodontitis through macrophage M1 polarization and osteoclast differentiation.
Parabacteroides distasonis promotes CXCL9 secretion of tumor-associated macrophages and enhances CD8(+)T cell activity to trigger anti-tumor immunity against anti-PD-1 treatment in non-small cell lung cancer mice.
Probiotic membrane vesicles ameliorate atherosclerotic plaques by promoting lipid efflux and polarization of foamy macrophages.
pH-responsive and self-adaptive injectable sodium alginate/carboxymethyl chitosan hydrogel accelerates infected wound healing by bacteriostasis and immunomodulation.
Inflammatory Microenvironment-Modulated Conductive Hydrogel Promotes Vascularized Bone Regeneration in Infected Bone Defects.
Tannic acid‑cerium nanoenzymes serve as broad-spectrum antioxidants to alleviate acute kidney injury by modulating macrophage polarization, mitophagy and endoplasmic reticulum stress.
Oxalate stimulates macrophage secretion of prostaglandin E2 to promote renal tubular epithelial cell osteogenesis.
Effect of Engineered Cyanobacterial Capsules on a Neurogenic Bladder after Spinal Cord Injury.
Bifunctional TRPV1 Targeted Magnetothermal Switch to Attenuate Osteoarthritis Progression.
SNORA5A regulates tumor-associated macrophage M1/M2 phenotypes via TRAF3IP3 in breast cancer.
Exosomal SLC16A1-AS1-induced M2 macrophages polarization facilitates hepatocellular carcinoma progression.
Rhein alleviates MPTP-induced Parkinson's disease by suppressing neuroinflammation via MAPK/IκB pathway.
Myeloid Deletion of Cdc42 Protects Liver From Hepatic Ischemia-Reperfusion Injury via Inhibiting Macrophage-Mediated Inflammation in Mice.
Pretreated MSCs with IronQ Transplantation Attenuate Microglia Neuroinflammation via the cGAS-STING Signaling Pathway.
The role of WTAP in regulating macrophage-mediated osteoimmune responses and tissue regeneration in periodontitis.
Assessing immune hepatotoxicity of troglitazone with a versatile liver-immune-microphysiological-system.
In situ MgO nanoparticle-doped Janus electrospun dressing against bacterial invasion and immune imbalance for irregular wound healing.
Enhanced enrichment of extracellular vesicles for laboratory and clinical research from drop-sized blood samples.
Microglia aggravate white matter injury via C3/C3aR pathway after experimental subarachnoid hemorrhage.
Study on the involvement of microglial S100A8 in neuroinflammation and microglia activation during migraine attacks.
Metabolic Control During Macrophage Polarization by a Citrate-Functionalized Scaffold for Maintaining Bone Homeostasis.
N-acetyltransferase 10 affects the proliferation of intrahepatic cholangiocarcinoma and M2-type polarization of macrophages by regulating C-C motif chemokine ligand 2.
Network Analysis of Gut Microbial Communities Reveals Key Reason for Quercetin Protects against Colitis.
GV-971 prevents severe acute pancreatitis by remodeling the microbiota-metabolic-immune axis.
Macrophage membrane-camouflaged biomimetic nanoparticles for rheumatoid arthritis treatment via modulating macrophage polarization.
Involvement of M2 macrophages polarization in PM2.5-induced COPD by upregulating MMP12 via IL4/STAT6 pathway.
Anti-colorectal cancer activity of mannatide from spent brewer's yeast by regulating immune cells and immune function in the tumor microenvironment.
CYP24A1 affected macrophage polarization through degradation of vitamin D as a candidate biomarker for ovarian cancer prognosis.
Rhein inhibits M1 polarization of BV2 microglia through MAPK/IκB signalling pathway and reduces neurotoxicity caused by neuroinflammation.
PKCα inhibitors promote breast cancer immune evasion by maintaining PD-L1 stability.
Knock-Out of IKKepsilon Ameliorates Atherosclerosis and Fatty Liver Disease by Alterations of Lipid Metabolism in the PCSK9 Model in Mice.
Bioactivity-Oriented Separation of "Pepper Alkaloids" from Piper sintenense Hatusima with Potential Antigouty Arthritis Activity.
Astragaloside IV augments anti-PD-1 therapy to suppress tumor growth in lung cancer by remodeling the tumor microenvironment.
Electroacupuncture attenuates depressive-like behaviors in poststroke depression mice through promoting hippocampal neurogenesis and inhibiting TLR4/NF-κB/NLRP3 signaling pathway.
Tumor associated antigens combined with carbon dots for inducing durable antitumor immunity.
The Neuroprotective Mechanisms of PPAR-γ: Inhibition of Microglia-Mediated Neuroinflammation and Oxidative Stress in a Neonatal Mouse Model of Hypoxic-Ischemic White Matter Injury.
Esculetin rebalances M1/M2 macrophage polarization to treat sepsis-induced acute lung injury through regulating metabolic reprogramming.
MMP-2-triggered, mitochondria-targeted PROTAC-PDT therapy of breast cancer and brain metastases inhibition.
Target-Engineered Liposomes Decorated with Nanozymes Alleviate Liver Fibrosis by Remodeling the Liver Microenvironment.
The role of disulfidptosis-associated LncRNA-LINC01137 in Osteosarcoma Biology and its regulatory effects on macrophage polarization.
Neutrophil extracellular traps promote M1 macrophage polarization in gouty inflammation via targeting hexokinase-2.
Versatile dopamine-functionalized hyaluronic acid-recombinant human collagen hydrogel promoting diabetic wound healing via inflammation control and vascularization tissue regeneration.
Turmeric-Derived Nanoparticles Functionalized Aerogel Regulates Multicellular Networks to Promote Diabetic Wound Healing.
Inhibition of OGG1 ameliorates pulmonary fibrosis via preventing M2 macrophage polarization and activating PINK1-mediated mitophagy.
Hypoxia-induced TREM1 promotes mesenchymal-like states of glioma stem cells via alternatively activating tumor-associated macrophages.
Podocyte SIRPα reduction aggravates lupus nephritis via promoting T cell inflammatory responses.
Photothermal and Photocatalytic Glycol Chitosan and Polydopamine-Grafted Oxygen Vacancy Bismuth Oxyiodide (BiO(1-x) I) Nanoparticles for the Diagnosis and Targeted Therapy of Diabetic Wounds.
A multifunctional composite nanoparticle with antibacterial activities, anti-inflammatory, and angiogenesis for diabetic wound healing.
LncRNA-HOXC-AS2 regulates tumor-associated macrophage polarization through the STAT1/SOCS1 and STAT1/CIITA pathways to promote the progression of non-small cell lung cancer.
Restoration of miR-299-3p promotes macrophage phagocytosis and suppresses malignant phenotypes in breast cancer carcinogenesis via dual-targeting CD47 and ABCE1.
Efficient Delivery of Lomitapide using Hybrid Membrane-Coated Tetrahedral DNA Nanostructures for Glioblastoma Therapy.
Multifunctional Biodegradable Conductive Hydrogel Regulating Microenvironment for Stem Cell Therapy Enhances the Nerve Tissue Repair.
Gut microbiota mediates the protective effects of β-hydroxybutyrate against cisplatin-induced acute kidney injury.
Prednisone combined with Dihydroartemisinin attenuates systemic lupus erythematosus by regulating M1/M2 balance through the MAPK signaling pathway.
Exosomes from adipose-derived stem cells regulate macrophage polarization and accelerate diabetic wound healing via the circ-Rps5/miR-124-3p axis.
A Graphene Composite Film Based Wearable Far-Infrared Therapy Apparatus (GRAFT) for Effective Prevention of Postoperative Peritoneal Adhesion.
Effects of a novel regimen of repetitive transcranial magnetic stimulation (rTMS) on neural remodeling and motor function in adult male mice with ischemic stroke.
The STAT3 inhibitor B9 alleviates lipopolysaccharide-induced acute lung injury through its anti-inflammatory effects.
Chishao - Fuzi herbal pair restore the macrophage M1/M2 balance in acute-on-chronic liver failure.
[Aqueous extract of Chuan Xiong Rhizoma enhances inhibitory effect of temozolomide against brain metastasis of melanoma in mice].
Potential Involvement of M1 Macrophage and VLA4/VCAM-1 Pathway in the Valvular Damage Due to Rheumatic Heart Disease.
Butyrate attenuates sympathetic activation in rats with chronic heart failure by inhibiting microglial inflammation in the paraventricular nucleus.
TREM1 facilitates the development of gastric cancer through regulating neutrophil extracellular traps-mediated macrophage polarization.
Zhen-wu-tang protects against myocardial fibrosis by inhibiting M1 macrophage polarization via the TLR4/NF-κB pathway.
Engineered Mesenchymal Stromal Cell Exosomes-Loaded Microneedles Improve Corneal Healing after Chemical Injury.
Virus-Mimetic Extracellular-Vesicle Vaccine Boosts Systemic and Mucosal Immunity via Immune Recruitment.
Microglial FoxO3a deficiency ameliorates ferroptosis-induced brain injury of intracerebral haemorrhage via regulating autophagy and heme oxygenase-1.
STING modulates iron metabolism to promote liver injury and inflammation in acute immune hepatitis.
Extracellular ATP (eATP) inhibits the progression of endometriosis and enhances the immune function of macrophages.
Regulation of the immune microenvironment by pioglitazone-loaded polylactic glycolic acid nanosphere composite scaffolds to promote vascularization and bone regeneration.
Carveol alleviates osteoarthritis progression by acting on synovial macrophage polarization transformation: An in vitro and in vivo study.
Discovery of β-sitosterol's effects on molecular changes in rat diabetic wounds and its impact on angiogenesis and macrophages.
Mannose-Integrated Nanoparticle Hitchhike Glucose Transporter 1 Recycling to Overcome Various Barriers of Oral Delivery for Alzheimer's Disease Therapy.
Mesencephalic astrocyte-derived neurotrophic factor (MANF) alleviates cerebral ischemia/reperfusion injury in mice by regulating microglia polarization via A20/NF-κB pathway.
Epigenetic modification of TWIST1 in macrophages promotes hypertension-induced atherosclerotic plaque instability.
Engineered Multifunctional Zinc-Organic Framework-Based Aggregation-Induced Emission Nanozyme for Accelerating Spinal Cord Injury Recovery.
High glucose impairs cognitive function through inducing mitochondrial calcium overload in Treg cells.
Metformin protects ovarian granulosa cells in chemotherapy-induced premature ovarian failure mice through AMPK/PPAR-γ/SIRT1 pathway.
Dictamnine Ameliorates DNFB-Induced Atopic Dermatitis Like Skin Lesions in Mice by Inhibiting M1 Macrophage Polarization and Promoting Autophagy.
C-C Motif Chemokine 2 Regulates Macrophage Polarization and Contributes to Myocardial Infarction Healing.
Macrophage Activation in Synovitis and Osteoarthritis of Temporomandibular Joint and Its Relationship with the Progression of Synovitis and Bone Remodeling.
Transplantation of fibrin-thrombin encapsulated human induced neural stem cells promotes functional recovery of spinal cord injury rats through modulation of the microenvironment.
Gut microbiome-based thiamine metabolism contributes to the protective effect of one acidic polysaccharide from Selaginella uncinata (Desv.) Spring against inflammatory bowel disease.
Biomimetic Corneal Stroma for Scarless Corneal Wound Healing via Structural Restoration and Microenvironment Modulation.
Three Birds, One Stone: An Osteo-Microenvironment Stage-Regulative Scaffold for Bone Defect Repair through Modulating Early Osteo-Immunomodulation, Middle Neovascularization, and Later Osteogenesis.
Mitochondrial-related genes PDK2, CHDH, and ALDH5A1 served as a diagnostic signature and correlated with immune cell infiltration in ulcerative colitis.
Chronic exposure to polystyrene microplastics induces renal fibrosis via ferroptosis.
Targeted reprogramming of tumor-associated macrophages for overcoming glioblastoma resistance to chemotherapy and immunotherapy.
MSCs-derived ECM functionalized hydrogel regulates macrophage reprogramming for osteoarthritis treatment by improving mitochondrial function and energy metabolism.
Licochalcone A loaded multifunctional chitosan hyaluronic acid hydrogel with antibacterial and inflammatory regulating effects to promote wound healing.
Preparation of recombinant type I collagen (PF-I-80) and its functional characterization and biomedical applications in wound healing.
Indole-3-Carboxaldehyde Inhibits Inflammatory Response and Lipid Accumulation in Macrophages Through the miR-1271-5p/HDAC9 Pathway.
Controlled Release of Ceria and Ferric Oxide Nanoparticles via Collagen Hydrogel for Enhanced Osteoarthritis Therapy.
Hierarchical Integration of Curcumin-Loaded CaCO(3) Nanoparticles and Black Phosphorus Nanosheets in Core/Shell Nanofiber for Cranial Defect Repair.
Kongensin A targeting PI3K attenuates inflammation-induced osteoarthritis by modulating macrophage polarization and alleviating inflammatory signaling.
Long-term hypothermia amplified neuroprotection by antagonizing intracranial pressure rebound after severe traumatic brain injury in rats.
Exosomes derived from minor salivary gland mesenchymal stem cells: a promising novel exosome exhibiting pro-angiogenic and wound healing effects similar to those of adipose-derived stem cell exosomes.
Identifying specific functional roles for senescence across cell types.
Polydopamine-coated bioactive glass for immunomodulation and odontogenesis in pulpitis.
Dissection of triple-negative breast cancer microenvironment and identification of potential therapeutic drugs using single-cell RNA sequencing analysis.
rTMS applied to the PFC relieves neuropathic pain and modulates neuroinflammation in CCI rats.
Neural epidermal growth factor-like 1 protein (Nell-1) alleviates periodontal tissue destruction in periodontitis by regulating the ratio of M2/M1 macrophage phenotypes.
Inhibiting PRMT1 protects against CoNV by regulating macrophages through the FGF2/PI3K/Akt pathway.
Fisetin Promotes Functional Recovery after Spinal Cord Injury by Inhibiting Microglia/Macrophage M1 Polarization and JAK2/STAT3 Signaling Pathway.
IRF4 induces M1 macrophage polarization and aggravates ulcerative colitis progression by the Bcl6-dependent STAT3 pathway.
A systematic strategy for investigating the pharmacological effects and mechanism of traditional Chinese medicinal formula: Guilin Xiguashuang as a case.
Enriched environment treatment promotes neural functional recovery together with microglia polarization and remyelination after cerebral ischemia in rats.
Ferrous/Ferric Ions Crosslinked Type II Collagen Multifunctional Hydrogel for Advanced Osteoarthritis Treatment.
Dehydroandrographolide facilitates M2 macrophage polarization by downregulating DUSP3 to inhibit sepsis-associated acute kidney injury.
Myricetin Oligomer Triggers Multi-Receptor Mediated Penetration and Autophagic Restoration of Blood-Brain Barrier for Ischemic Stroke Treatment.
FDA compound library screening Baicalin upregulates TREM2 for the treatment of cerebral ischemia-reperfusion injury.
Transcriptome sequencing reveals novel biomarkers and immune cell infiltration in esophageal tumorigenesis.
Pathological BBB Crossing Melanin-Like Nanoparticles as Metal-Ion Chelators and Neuroinflammation Regulators against Alzheimer's Disease.
CD86 Is Associated with Immune Infiltration and Immunotherapy Signatures in AML and Promotes Its Progression.
Periventricular Microglia Polarization and Morphological Changes Accompany NLRP3 Inflammasome-Mediated Neuroinflammation after Hypoxic-Ischemic White Matter Damage in Premature Rats.
Identifying Macrophage-Related Genes in Ulcerative Colitis Using Weighted Coexpression Network Analysis and Machine Learning.
Based on disulfidptosis-related glycolytic genes to construct a signature for predicting prognosis and immune infiltration analysis of hepatocellular carcinoma.
Engineered exosomes derived from miR-132-overexpresssing adipose stem cells promoted diabetic wound healing and skin reconstruction.
Macrophage-Derived Cathepsin S Remodels the Extracellular Matrix to Promote Liver Fibrogenesis.
Early depletion of M1 macrophages retards the progression of glucocorticoid-associated osteonecrosis of the femoral head.
Ursolic Acid Alleviates Neuroinflammation after Intracerebral Hemorrhage by Mediating Microglial Pyroptosis via the NF-κB/NLRP3/GSDMD Pathway.
The crosstalk between M1 macrophage polarization and energy metabolism disorder contributes to polystyrene nanoplastics-triggered testicular inflammation.
In vitro acne disease model from inertial focusing effect for studying the interactions between sebocyte glands and macrophages.
Knockdown of repulsive guidance molecule a promotes polarization of microglia into an anti-inflammatory phenotype after oxygen-glucose deprivation-reoxygenation in vitro.
CTRP6 regulates M1 macrophage polarization via the PPAR-γ/NF-κB pathway and reprogramming glycolysis in recurrent spontaneous abortion.
Silk Acid as an Implantable Biomaterial for Tissue Regeneration.
Irf7 regulates the expression of Srg3 and ferroptosis axis aggravated sepsis-induced acute lung injury.
Role of low-intensity pulsed ultrasound in regulating macrophage polarization to accelerate tendon-bone interface repair.
Spontaneous immunomodulation and regulation of angiogenesis and osteogenesis by Sr/Cu-borosilicate glass (BSG) bone cement to repair critical bone defects.
Bioengineered stem cell membrane functionalized nanoparticles combine anti-inflammatory and antimicrobial properties for sepsis treatment.
Dual role of ANGPTL8 in promoting tumor cell proliferation and immune escape during hepatocarcinogenesis.
Exploring the effect of Er miao San-containing serum on macrophage polarization through miR-33/NLRP3 pathway.
Apigenin Alleviates Autoimmune Uveitis by Inhibiting Microglia M1 Pro-Inflammatory Polarization.
Role of nuclear factor of activated T Cells-1 in Sepsis-induced behavioral deficits in mice.
Large extracellular vesicles secreted by human iPSC-derived MSCs ameliorate tendinopathy via regulating macrophage heterogeneity.
Cadmium contributes to atherosclerosis by affecting macrophage polarization.
Synthesis of oxidized sodium alginate and its electrospun bio-hybrids with zinc oxide nanoparticles to promote wound healing.
Metformin Attenuates the Inflammatory Response via the Regulation of Synovial M1 Macrophage in Osteoarthritis.
Extracellular vesicle-derived LINC00511 promotes glycolysis and mitochondrial oxidative phosphorylation of pancreatic cancer through macrophage polarization by microRNA-193a-3p-dependent regulation of plasminogen activator urokinase.
Intracellular hydrogelation of macrophage conjugated probiotics for hitchhiking delivery and combined treatment of colitis.
Erythrocyte membrane-camouflaged DNA-functionalized upconversion nanoparticles for tumor-targeted chemotherapy and immunotherapy.
Photo-Responsive Hydrogel for Contactless Dressing Change to Attenuate Secondary Damage and Promote Diabetic Wound Healing.
SGLT2 inhibitor dapagliflozin alleviates intramyocardial hemorrhage and adverse ventricular remodeling via suppressing hepcidin in myocardial ischemia-reperfusion injury.
MCP-1-Loaded Poly(l-lactide-co-caprolactone) Fibrous Films Modulate Macrophage Polarization toward an Anti-inflammatory Phenotype and Improve Angiogenesis.
Nonenzymatic function of DPP4 promotes diabetes-associated cognitive dysfunction through IGF-2R/PKA/SP1/ERp29/IP3R2 pathway-mediated impairment of Treg function and M1 microglia polarization.
Exploration of the mechanism by which Huangqi Guizhi Wuwu decoction inhibits Lps-induced inflammation by regulating macrophage polarization based on network pharmacology.
Chronic Microcystin-LR-Induced α-Synuclein Promotes Neuroinflammation Through Activation of the NLRP3 Inflammasome in Microglia.
Castor1 overexpression regulates microglia M1/M2 polarization via inhibiting mTOR pathway.
Converting bacteria into autologous tumor vaccine via surface biomineralization of calcium carbonate for enhanced immunotherapy.
SUV39H1 is a prognosis and immune microenvironment-related biomarker in diffuse large B-cell lymphoma.
Hollow copper sulfide nanoparticles carrying ISRIB for the sensitized photothermal therapy of breast cancer and brain metastases through inhibiting stress granule formation and reprogramming tumor-associated macrophages.
Constitutive aryl hydrocarbon receptor facilitates the regenerative potential of mouse bone marrow mesenchymal stromal cells.
Melatonin ameliorates neurological deficits through MT2/IL-33/ferritin H signaling-mediated inhibition of neuroinflammation and ferroptosis after traumatic brain injury.
Reversal of Pulmonary Fibrosis: Human Umbilical Mesenchymal Stem Cells from Wharton's Jelly versus Human-Adipose-Derived Mesenchymal Stem Cells.
Identification of the Prognostic Biomarkers CBX6 and CBX7 in Bladder Cancer.
Regulatory Effects of Three-Dimensional Cultured Lipopolysaccharide-Pretreated Periodontal Ligament Stem Cell-Derived Secretome on Macrophages.
Antiliver Fibrosis Formula of Fuzheng Huayu Alleviates Inflammatory Response.
Cayratia japonica Prevents Ulcerative Colitis by Promoting M2 Macrophage Polarization through Blocking the TLR4/MAPK/NF-κB Pathway.
NCOA4-Mediated Ferroptosis in Bronchial Epithelial Cells Promotes Macrophage M2 Polarization in COPD Emphysema.
Self-Assembly Catalase Nanocomplex Conveyed by Bacterial Vesicles for Oxygenated Photodynamic Therapy and Tumor Immunotherapy.
Novel recombinant protein flagellin A N/C attenuates experimental autoimmune encephalomyelitis by suppressing the ROS/NF-κB/NLRP3 signaling pathway.
Qing-Wen-Jie-Re Mixture Ameliorates Poly (I:C)-Induced Viral Pneumonia Through Regulating the Inflammatory Response and Serum Metabolism.
TGFBI secreted by tumor-associated macrophages promotes glioblastoma stem cell-driven tumor growth via integrin αvβ5-Src-Stat3 signaling.
Non-invasive photobiomodulation treatment in an Alzheimer Disease-like transgenic rat model.
Protective effects of (R)-enantiomers but not (S)-enantiomers of β2-adrenergic receptor agonists against acute colitis: The role of β2AR.
A Combination Therapy Using Electrical Stimulation and Adaptive, Conductive Hydrogels Loaded with Self-Assembled Nanogels Incorporating Short Interfering RNA Promotes the Repair of Diabetic Chronic Wounds.
Engineered Bacterial Outer Membrane Vesicles as Controllable Two-Way Adaptors to Activate Macrophage Phagocytosis for Improved Tumor Immunotherapy.
A ROS-Responsive Liposomal Composite Hydrogel Integrating Improved Mitochondrial Function and Pro-Angiogenesis for Efficient Treatment of Myocardial Infarction.
Ultrasound-augmented anti-inflammatory exosomes for targeted therapy in rheumatoid arthritis.
Application of Bone Marrow-Derived Macrophages Combined with Bone Mesenchymal Stem Cells in Dual-Channel Three-Dimensional Bioprinting Scaffolds for Early Immune Regulation and Osteogenic Induction in Rat Calvarial Defects.
Pirfenidone ameliorates pulmonary inflammation and fibrosis in a rat silicosis model by inhibiting macrophage polarization and JAK2/STAT3 signaling pathways.
Curcumin attenuates cadmium-induced atherosclerosis by regulating trimethylamine-N-oxide synthesis and macrophage polarization through remodeling the gut microbiota.
Chondroitin sulfate microspheres anchored with drug-loaded liposomes play a dual antioxidant role in the treatment of osteoarthritis.
An increase in Semaphorin 3A biases the axonal direction and induces an aberrant dendritic arborization in an in vitro model of human neural progenitor differentiation.
Enhanced Immunotherapy Based on Combining the Pro-phagocytosis and Anti-phagocytosis Checkpoint Blockade for Tumor Eradication.
Microglia-derived TNF-α inhibiting GABAergic neurons in the anterior lateral bed nucleus of the stria terminalis precipitates visceral hypersensitivity induced by colorectal distension in rats.
Exercise-induced neuroprotection against cerebral ischemia/reperfusion injury is mediated via alleviating inflammasome-induced pyroptosis.
Integrated analysis reveals the molecular features of fibrosis in triple-negative breast cancer.
Photosynthetic microorganisms coupled photodynamic therapy for enhanced antitumor immune effect.
Thiamine pretreatment improves endotoxemia-related liver injury and cholestatic complications by regulating galactose metabolism and inhibiting macrophage activation.
Embryonic stem cell-derived mesenchymal stem cells alleviate skeletal muscle injury induced by acute compartment syndrome.
Establishment of an Artificial Neural Network Model Using Immune-Infiltration Related Factors for Endometrial Receptivity Assessment.
Incorporation of magnesium oxide nanoparticles into electrospun membranes improves pro-angiogenic activity and promotes diabetic wound healing.
Surface Coating of Pulmonary siRNA Delivery Vectors Enabling Mucus Penetration, Cell Targeting, and Intracellular Radical Scavenging for Enhanced Acute Lung Injury Therapy.
Caffeine treatment started before injury reduces hypoxic-ischemic white-matter damage in neonatal rats by regulating phenotypic microglia polarization.
Scorpion venom polypeptide governs alveolar macrophage M1/M2 polarization to alleviate pulmonary fibrosis.
Sonosensitizer nanoplatform-mediated sonodynamic therapy induced immunogenic cell death and tumor immune microenvironment variation.
TREM2 activation alleviates neural damage via Akt/CREB/BDNF signalling after traumatic brain injury in mice.
An Injectable Hydrogel Scaffold Loaded with Dual-Drug/Sustained-Release PLGA Microspheres for the Regulation of Macrophage Polarization in the Treatment of Intervertebral Disc Degeneration.
Artificial Intelligence-Assisted Bioinformatics, Microneedle, and Diabetic Wound Healing: A "New Deal" of an Old Drug.
MEF2C promotes M1 macrophage polarization and Th1 responses.
A positive feedback loop: RAD18-YAP-TGF-β between triple-negative breast cancer and macrophages regulates cancer stemness and progression.
Cell-free fat extract attenuates osteoarthritis via chondrocytes regeneration and macrophages immunomodulation.
Receptor-Interacting Protein Kinase 3 Inhibition Prevents Cadmium-Mediated Macrophage Polarization and Subsequent Atherosclerosis via Maintaining Mitochondrial Homeostasis.
Neu-P11 - a novel melatonin receptor agonist, could improve the features of type-2 diabetes mellitus in rats.
P4HA1 Down-Regulation Inhibits Glioma Invasiveness by Promoting M1 Microglia Polarization.
Pentraxin-3 inhibits milky spots metastasis of gastric cancer by inhibiting M2 macrophage polarization.
Bacterial navigation for tumor targeting and photothermally-triggered bacterial ghost transformation for spatiotemporal drug release.
Donor BMSC-derived small extracellular vesicles relieve acute rejection post-renal allograft through transmitting Loc108349490 to dendritic cells.
Evaluation of immune status in testis and macrophage polarization associated with testicular damage in patients with nonobstructive azoospermia.
The Protective Role of Yin-Yang 1 in Cardiac Injury and Remodeling After Myocardial Infarction.
Ripened Pu-Erh Tea Improved the Enterohepatic Circulation in a Circadian Rhythm Disorder Mice Model.
Splenic CD4(+) and CD8(+) T-cells highly expressed PD-1 and Tim-3 in cirrhotic patients with HCV infection and portal hypertension.
Light-controlled oxygen production and collection for sustainable photodynamic therapy in tumor hypoxia.
Astragalus polysacharin inhibits hepatocellular carcinoma-like phenotypes in a murine HCC model through repression of M2 polarization of tumour-associated macrophages.
FNDC5 induces M2 macrophage polarization and promotes hepatocellular carcinoma cell growth by affecting the PPARγ/NF-κB/NLRP3 pathway.
The impact of ExHp-CD (outer membrane vesicles) released from Helicobacter pylori SS1 on macrophage RAW 264.7 cells and their immunogenic potential.
SCARF1 promotes M2 polarization of Kupffer cells via calcium-dependent PI3K-AKT-STAT3 signalling to improve liver transplantation.
EB virus-induced ATR activation accelerates nasopharyngeal carcinoma growth via M2-type macrophages polarization.
Inhibiting HMGB1-RAGE axis prevents pro-inflammatory macrophages/microglia polarization and affords neuroprotection after spinal cord injury.
Comparison of reversal of rat pulmonary fibrosis of nintedanib, pirfenidone, and human umbilical mesenchymal stem cells from Wharton's jelly.
A Comparison of Splenic Pathologic Change and Immune Function in HBV-Related Portal Hypertension and Chinese Budd-Chiari Syndrome Patients with Hypersplenism.
Macrophage Spheroids with Chronological Phenotype Shifting To Promote Therapeutic Angiogenesis in Critical Limb Ischemia.
Soluble epoxide hydrolase inhibition enhances anti-inflammatory and antioxidative processes, modulates microglia polarization, and promotes recovery after ischemic stroke.
Electroacupuncture Pretreatment Alleviates Cerebral Ischemic Injury Through α7 Nicotinic Acetylcholine Receptor-Mediated Phenotypic Conversion of Microglia.
High-Mobility Group Box 1 Contributes to Cerebral Cortex Injury in a Neonatal Hypoxic-Ischemic Rat Model by Regulating the Phenotypic Polarization of Microglia.
Baicalein administered in the subacute phase ameliorates ischemia-reperfusion-induced brain injury by reducing neuroinflammation and neuronal damage.
Inhibition of microRNA-124a attenuates non-alcoholic fatty liver disease through upregulation of adipose triglyceride lipase and the effect of liraglutide intervention.
KDM3A inhibition modulates macrophage polarization to aggravate post-MI injuries and accelerates adverse ventricular remodeling via an IRF4 signaling pathway.
C1q/TNF-related protein-9 promotes macrophage polarization and improves cardiac dysfunction after myocardial infarction.
Prolonged release of bone morphogenetic protein-2 in vivo by gene transfection with DNA-functionalized calcium phosphate nanoparticle-loaded collagen scaffolds.
Hydrogel derived from porcine decellularized nerve tissue as a promising biomaterial for repairing peripheral nerve defects.
Cathelicidin-WA polarizes E. coli K88-induced M1 macrophage to M2-like macrophage in RAW264.7 cells.
Photobiomodulation therapy promotes neurogenesis by improving post-stroke local microenvironment and stimulating neuroprogenitor cells.
TSG-6 attenuates inflammation-induced brain injury via modulation of microglial polarization in SAH rats through the SOCS3/STAT3 pathway.
Treadmill Exercise Exerts Neuroprotection and Regulates Microglial Polarization and Oxidative Stress in a Streptozotocin-Induced Rat Model of Sporadic Alzheimer's Disease.
Hu J, Xu Y, Zhou D, Chen K, Jiang J, Lin M, Chen W, Wu J, Jiang H, Zhu M, Zhang B, Xu K, Wei P
Biomaterials research 2026;30:0309
Biomaterials research 2026;30:0309
Tailoring Polydopamine Nanoparticle Size Through Synthesis Conditions and Defining Their Antioxidant and Neuroprotective Efficacy.
Huang Q, Zou J, Luan F, Shi Y
International journal of nanomedicine 2026;21:581479
International journal of nanomedicine 2026;21:581479
After Traumatic Brain Injury, EPHA4 Enhances Endoplasmic Reticulum Stress to Promote M1 Microglial Polarization Through the MAPK Signaling Pathway.
Tan Y, Xia J, Liu M, Deng S, Wu H, Qian C
Mediators of inflammation 2026;2026:5595023
Mediators of inflammation 2026;2026:5595023
Microglial TIA1-mediated stress granules promote neuroinflammation and aggravate neuron loss in mice after ischemic stroke by inhibiting IGF2 signaling.
Qian Y, Yu H, Dong J, Liu J, Han J, Zheng T, Zhang W, Wang L, Huang Z, Wang Y
Theranostics 2026;16(5):2627-2648
Theranostics 2026;16(5):2627-2648
Dissolvable microneedles loaded with denosumab alleviate knee osteoarthritis in rodent and canine models by inhibiting macrophage senescence.
Ming C, Bi D, Tian H, Liu W, Li H, Hu Y, Song Z, Xu D, Xu H, Li H, Lan S, Xu W, Chen W, Li Q, Feng J, Cao Q, Wang X, Fan P, Zhu J, Yu W, Ming C, Dai Z, Liu Y, Tong W
Theranostics 2026;16(1):325-344
Theranostics 2026;16(1):325-344
Influence of micro- and nanoscale cues on immune factors secretion: implications for immunomodulation.
Luo Z, Zheng Y, Lin W, Zhang L, Huang X, Li Y, He Y, Shen X, Zhang H, Huang W, Cui W, Chen L
Regenerative biomaterials 2026;13:rbaf130
Regenerative biomaterials 2026;13:rbaf130
A near-infrared regulated programmable multi-mode periosteum scaffold for sequential healing of infected bone defects.
Yin Y, Cai Y, Dang P, Zeng W, Wang L, Yan X, Luo Z, Liu W, Zhu Y, Chen L, Zhang C
Bioactive materials 2026 Sep;63:56-72
Bioactive materials 2026 Sep;63:56-72
Aspirin-induced mesenchymal stem cell-derived extracellular vesicles promote osteochondral regeneration by reprogramming macrophages.
Xie C, Peng X, Wang Y, Ma Y, Jiang M, Zhang B, Xia C, Wu Y, Fang H, Wang S
Biomaterials 2026 Sep;332:124151
Biomaterials 2026 Sep;332:124151
Pomegranate-inspired bionic microgel/periosteum composite harnessing reactive oxygen species for immune-engineered bone regeneration.
Feng Z, Jin M, Li M, Guo J, Guo S, Yang H, Sun X
Journal of controlled release : official journal of the Controlled Release Society 2026 May 10;393:114818
Journal of controlled release : official journal of the Controlled Release Society 2026 May 10;393:114818
Huangtu Decoction regulates macrophage M1/M2 polarization to alleviate DSS- and rhubarb-induced Deficiency-Cold Pattern in Ulcerative Colitis by inhibiting the HIF-1α signaling pathway.
Chen Y, Wei H, Dai A, Fu Y, Zhang Z, Hong R, Liu H, Jiao Y, Wan J, Chen W
Journal of ethnopharmacology 2026 May 10;362:121353
Journal of ethnopharmacology 2026 May 10;362:121353
Immune regulative GelMA&Zn(2+)/Ce(3+)-whitlockite scaffolds with continuous ions release for bone regeneration.
Jin M, Xia M, Wang T, Zhao Y, Xu D, Wu L, Liu T, Li T, Xu D, Yang H, Xu X
Bioactive materials 2026 Mar;57:578-600
Bioactive materials 2026 Mar;57:578-600
Dual functional properties of a probiotic biofilm-decorated bone substitute to combat infection and promote osteoimmunomodulation.
Song S, Zhang W, Zhuang H, Wei W, Cheng S, Qiao D, Xiao Y, Zhang Y, Yan F
Bioactive materials 2026 Mar;57:457-473
Bioactive materials 2026 Mar;57:457-473
Engineering multifunctional microspheres for sequential regulation of osteoimmune microenvironment and bone remodeling balance to promote regeneration of osteoporotic bone defects.
Luo Z, Ma J, Yang Y, Zhang H, Du Y, Dai J, Wang Y, Zhang W, Ma X, Lai Y
Journal of orthopaedic translation 2026 Mar;57:101054
Journal of orthopaedic translation 2026 Mar;57:101054
NLRP3 Mediates Submandibular Gland Regeneration in Duct Ligation/De-Ligation Model.
Zhang Y, Zhang H, Li D, Zhang Y, Qin L
Oral diseases 2026 Mar;32(3):772-785
Oral diseases 2026 Mar;32(3):772-785
M2 macrophage-derived exosome nanoplatform for targeted H(2)S delivery to alleviate hepatic ischemia-reperfusion injury via synergistic anti-oxidative, anti-inflammatory, and anti-ferroptotic effects.
Zuo T, Shi C, Li J, Li D, Luo X, Xu M, Su M, Lu H, Zhang Y, Hu X, Zhou Q, Shubhra QTH, He X, Cai X
Acta biomaterialia 2026 Mar;212:593-612
Acta biomaterialia 2026 Mar;212:593-612
An Injectable Thermosensitive Hydrogel Codelivering Permeability-Promoting Nintedanib-loaded Phase-transition Nanoparticles and Doxorubicin to Potentiate Immunogenic Cell Death in Triple-Negative Breast Cancer for Chemoimmunotherapy.
Zou X, Li S, Jin Z, Huang S, Niu R, Fu N, Li W, Gao J, Wang Z
ACS applied materials & interfaces 2026 Mar 4;18(8):12549-12572
ACS applied materials & interfaces 2026 Mar 4;18(8):12549-12572
ZXDB Drives Macrophage Inflammatory Programming in Sepsis-Induced Acute Kidney Injury by Recruiting EIF4A3 to Enhance ACACA Translation.
Wu H, Gang W, Wang L, Sun J, Li S, Guo Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Mar 31;40(6):e71657
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Mar 31;40(6):e71657
Tailored Porous Bimetallic Nanozyme Platform for Full-Cycle Therapeutics of Intestinal Ischemia/Reperfusion.
Qiu C, Xian W, Wang M, Zhao G, Zhang Y, Zhou Z, Sheng B, Zhen Z, Liu X, Diao S, Tu M, Qiu C, Wang H, Zhang J, Zhu P, Li T
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar 31;:e20748
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar 31;:e20748
Microglial PRMT2IP alleviates ischemia-induced brain injury.
Zhang M, Cai J, Su W, Zeng Q, Zhang H, Deng J, Zhai B, Xiao H, Zhu G, Gao R, Qiu J, Bian Z, Luan G, Wang R
Brain, behavior, and immunity 2026 Mar 24;136:106558
Brain, behavior, and immunity 2026 Mar 24;136:106558
A core-shell microneedle platform for the spatiotemporal codelivery of dual-agent therapeutics precisely orchestrates diabetic wound healing.
Zhan Y, Zhang Z, Zhang Z, Lin M, Liu H, Abulimiti D, Aihemaiti S, Kan Y, Tan J, Chen X, Tao S
Journal of nanobiotechnology 2026 Mar 17;24(1)
Journal of nanobiotechnology 2026 Mar 17;24(1)
Cornuside alleviates microglia-mediated neuroinflammation to ameliorate chronic neuropathic pain-induced cognitive impairment via the Nrf2/Sirt3 signaling pathway.
Yin J, Chu L, Chen Y, Fan L, Wang X, Wen Y, He L
Free radical biology & medicine 2026 Jun;249:292-307
Free radical biology & medicine 2026 Jun;249:292-307
AICAR improves depression-like behaviors and is associated with hippocampal AMPK activation and modulation of neurogenesis and neuroinflammation in a microbiota disruption model.
Takahashi K, Kurokawa K, Kawaguchi R, Takeda H, Tsuji M
Neurochemistry international 2026 Jun;196:106152
Neurochemistry international 2026 Jun;196:106152
Network pharmacology-guided self-assembling quercetin hydrogel from Astragalus membranaceous accelerates diabetic wound healing.
Liu M, Zhou H, Wang J, Wang Y, Cai C, Han C, Dong L, Wang X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158137
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158137
Intermittent fasting attenuates ovarian chronic inflammation in obese mice by inhibiting the CXCL12-CXCR4 axis.
Chen X, Han Z, Yu X, Hao X
International immunopharmacology 2026 Jun 15;179:116603
International immunopharmacology 2026 Jun 15;179:116603
Diallyl Trisulfide Suppresses Tumor-Associated Macrophage M2-Like Polarization and Recruitment and Improves the Tumor Microenvironment Through Blocking CCL5/STAT3 Signaling Pathway Against Lung Cancer.
Xie C, Yin J, Zhu J
Phytotherapy research : PTR 2026 Jan;40(1):318-333
Phytotherapy research : PTR 2026 Jan;40(1):318-333
Polydopamine nanoparticle-enhanced stem cell spheroid-derived decellularized extracellular matrix with antioxidant and tissue-adhesive properties for brain repair.
Yang PC, Kao YC, Lin YP, Chen GH, Ho CH, Liu SW, Huang SC, Lee PY, Chen L, Huang CC
Biomaterials 2026 Jan;324:123530
Biomaterials 2026 Jan;324:123530
MCU knockdown mitigates post-stroke neuroinflammation through SLC33A1-mediated reduction of NR4A1 acetylation.
Zhou Z, Liu L, Zhou Y, Yan Y, Wang B, Lv X, Qin J, Liu Z, Liu Y, Meng Z, You L, Zhao M, Wang X, Pei G, Bai G, Meng C, Liu X
Brain research bulletin 2026 Jan;234:111676
Brain research bulletin 2026 Jan;234:111676
Salidroside ameliorates experimental autoimmune neuritis by dually modulating neuroinflammation and immune homeostasis via PI3K/AKT signaling.
Gu T, Wang L, Kang X, Yu C, Shen K, Song M, Gao Y, Wang G, Wang Z
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2026 Jan;23(1):e00769
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2026 Jan;23(1):e00769
Coxsackievirus B3 regulates macrophage polarization through ANXA3 to promote the development of myocarditis.
Chen Y, Liu X, Meng L, Li B, Su Z, Jiang L, Wu Y, Zhang X
Molecular immunology 2026 Jan;189:68-81
Molecular immunology 2026 Jan;189:68-81
USP11-PGAM5 Axis Promotes Neurotoxic Astrocyte Reactivity by Aggravating the mtDNA-cGAS-STING Pathway After Intracerebral Hemorrhage.
He J, Qin Z, Cai Y, Liu H, Wang T, Hu Q, Xu Y, Yang P, Wu X, Qu Y, Guo W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(1):e14283
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(1):e14283
Hyaluronan of Different Molecular Weights Exerts Distinct Therapeutic Effects on Bleomycin-Induced Acute Respiratory Distress Syndrome.
Peng ST, Lai CY, Ko TL, Hsu CH, Chen IY, Jiang YC, Chu KA, Fu YS
International journal of molecular sciences 2026 Jan 6;27(2)
International journal of molecular sciences 2026 Jan 6;27(2)
Single-cell transcriptomics uncover RNF130-mediated TNF-α pathway activation and worenine synergy with paclitaxel in breast cancer.
Hu M, Huang L, Deng H, Chen Z, Cheng G, Liu X
Clinical epigenetics 2026 Jan 24;18(1):32
Clinical epigenetics 2026 Jan 24;18(1):32
Caveolin-2 Knockdown Alleviated Sepsis-induced Acute Lung Injury Via Promoting Macrophage M2 Polarization and Inhibiting Apoptosis by Hippo Signaling Pathway.
Xue X, Gao F, Chen J, Wang M, Wu X, Liao H, Sun Z, Nie S
Inflammation 2026 Jan 19;49(1):66
Inflammation 2026 Jan 19;49(1):66
Explore the chemical components of Angong Niuhuang Pill and its potential mechanisms for fever treatment based on UHPLC-Q-Exactive orbitrap HRMS, transcriptomics, and experiment verification.
Gao F, An J, Jia S, Zhu Z, Zhang Z, Li Y, Jiao J, Li S, Liu Y, Yin H, Xu B, Lei H
Journal of ethnopharmacology 2026 Jan 10;354:120542
Journal of ethnopharmacology 2026 Jan 10;354:120542
Mechanistic insights into the effects of Norisoboldine on intestinal immunity and neuroinflammation in a mouse model of slow transit constipation with depression.
Wu B, Wu J, Bai X, Zhou Q, Wang X
Journal of ethnopharmacology 2026 Jan 10;354:120479
Journal of ethnopharmacology 2026 Jan 10;354:120479
β-Aminoisobutyric acid targets AMPK to suppress macrophage pro-inflammatory phenotype and alleviate lipopolysaccharide-induced sepsis in mice.
Hu X, Wang C, Zou P, Wu T, Shi H, Gao B, Zhu L, Duan R
International immunopharmacology 2026 Jan 1;168(Pt 1):115781
International immunopharmacology 2026 Jan 1;168(Pt 1):115781
Effect and Mechanism of Apoptotic Bodies from Inflammatory Periodontal Ligament Stem Cells on Macrophage M1 Polarisation.
Weng J, Zhang Z, Zeng L, Xia J, Xu Z, Zhu G, Zhang H, Wang J, Pathak JL, Yu L
International dental journal 2026 Feb;76(1):103981
International dental journal 2026 Feb;76(1):103981
Genistein Ameliorates the Ischemic State of Random Skin Flap by Regulating Macrophage Polarization Through AMPK/SIRT1 Signaling Pathway.
Fu Y, Ye C, Zhu Y, Chen T, Li Z, Chen Y
Phytotherapy research : PTR 2026 Feb;40(2):420-435
Phytotherapy research : PTR 2026 Feb;40(2):420-435
Self-regulating neohesperidin/silk fibroin composite aerogel for enhanced wound healing via pH-responsive release.
Wang Z, Zhu X, Wang X, Shi Z, Zhang Z, Wang Z, Xie X, Li X, Jiang K, Liu H, Zhou L, Lv D
Materials today. Bio 2026 Feb;36:102637
Materials today. Bio 2026 Feb;36:102637
Programmed temporal modulation by using a magnetoelectric wound dressing for ultra-fast early-stage wound healing.
Zhao B, Sun J, Xu Y, Li J, Xie K, Zhou C, Su B, Chen L
Biomaterials 2026 Feb;325:123569
Biomaterials 2026 Feb;325:123569
Blastocyst Structure-Inspired Core-Shell Stem Cell Microspheres with Hyperoside Delivery for Endometrial Regeneration.
Lu S, Xue H, Zhang F, Du Y, Xu X, Liu L, Zhou S, Yang L, Guan Y
Advanced healthcare materials 2026 Feb;15(6):e02293
Advanced healthcare materials 2026 Feb;15(6):e02293
A Biomimetic Norepinephrine-Loaded Aligned Mineralized Collagen Scaffold for Coordinated Neurovascular, Osteogenic, and Immunomodulatory Repair of Critical-Sized Bone Defects.
Ren Z, Wu Z, Wu A, Zhang H, Lu J, Zhang J, Weng J, Zhang J, Chen S, Tan H, Guo T
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(8):e18807
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(8):e18807
Kaempferol Alleviates Glucocorticoid-Induced Osteonecrosis of the Femoral Head by Modulating Macrophage M1/M2 Polarization Through RhoA/ROCK-Mediated Mitophagy Activation.
Zhang Y, Zhao Y, Zhang S, Lei T, Xiang B, Zhang X, Nan K, Fan L
Biomedicines 2026 Feb 9;14(2)
Biomedicines 2026 Feb 9;14(2)
ICAM2 loss drives 5-fluorouracil resistance via TGF-β/Smad/SP1/PTN-dependent apoptosis evasion and macrophage remodeling in gastric cancer.
Tang XC, Chen ZJ, Chen CY, Qiu J, Huang JT, Tan RC, Li WY, Chen H, Yang ZL
World journal of gastroenterology 2026 Feb 7;32(5):115301
World journal of gastroenterology 2026 Feb 7;32(5):115301
A dual-action nanoparticle approach for spinal cord injury treatment: ferroptosis inhibition, inflammation control, and Myelin preservation.
Xue C, Zhou Y, Lin H, Li Z, Xiao Y, Yang J, Lu M, Qin Y, Song D, Chen W, Xu J, Zuo Y, Wang Z, Jiang C
Journal of nanobiotechnology 2026 Feb 12;24(1):158
Journal of nanobiotechnology 2026 Feb 12;24(1):158
Hypoxia-preconditioned cardiomyocyte-derived extracellular vesicles alleviate myocardial ischemic injury by reprogramming macrophage polarization via the Fgl2/NF-κB pathway.
Zhang Z, Shen H, Zhang S, Zhou J, Zhang M, Wang Y, Zheng Y, Chang Y, Liang X, Hu X, Gao W
International immunopharmacology 2026 Feb 1;170:116077
International immunopharmacology 2026 Feb 1;170:116077
Synergism of microgrooves and gallium phytate coating on PEKK based percutaneous implant with photothermal effect facilitates biological sealing of skin tissue for combating infection.
Sun P, Zhou Y, Ma S, Xie S, Li W, Wei J, Niu Y
Biomaterials advances 2026 Aug;185:214886
Biomaterials advances 2026 Aug;185:214886
Mossy-textured hydroxyapatite-modified poly (lactic-co-glycolic acid) microspheres promote collagen regeneration via calcium/TGF-β and chemokine signaling pathways in soft tissue augmentation.
Chang D, Cao L, Han L, Bai Z, Guo Z, Wang Y, Zheng Y, Sheng J, Tan H, Chen X, Ye F, Guo T, Weng J
Bioactive materials 2026 Apr;58:612-631
Bioactive materials 2026 Apr;58:612-631
Tirzepatide mitigates atherosclerosis progression and modulates oxLDL-mediated proatherogenic effects in macrophages: evidence for M1/M2 homeostasis restoration.
Kang M, Ren H, Zhen Y, Liu L, Xu Q, Ma Y, Zhang L, Jia H, Chen Q, Jiang Y, Gao J, Liu Y, Zhou MS
Archives of pharmacal research 2026 Apr;49(4):554-574
Archives of pharmacal research 2026 Apr;49(4):554-574
HMGA2 promotes hepatocellular carcinoma progression by regulating tumor-associated macrophage via Notch1/CCL2 signaling.
Xing Z, Xun J, Deng L
Molecular and cellular biochemistry 2026 Apr;481(4):1677-1693
Molecular and cellular biochemistry 2026 Apr;481(4):1677-1693
Core fucosylation of NCEH1 by FUT8 promotes progression of high-grade serous ovarian cancer by driving tumor-associated macrophage M2 polarization.
Pei X, Wang F, Liu X, Lei Y, Chen Y, Liu B, Sun R, Li P, Bi J, Liu S
Oncogene 2026 Apr;45(12):1128-1144
Oncogene 2026 Apr;45(12):1128-1144
3D-printed titanium scaffolds coated with a multifunctional photothermal-responsive hydrogel promote osteoporotic bone defect repair.
Wang C, Wang Y, Li X, Cao H, Wang C, Han S, Chen H, Zhao X, Yang S
Materials today. Bio 2026 Apr;37:102879
Materials today. Bio 2026 Apr;37:102879
Wine-Processed Cornus officinalis Ameliorates Osteoarthritis via Modulating M1/M2 Macrophage Polarization.
Fu Y, Zhao M, Huang X, Ren Y, Wang W
Journal of cellular and molecular medicine 2026 Apr;30(7):e71113
Journal of cellular and molecular medicine 2026 Apr;30(7):e71113
Senescence-Driven Remodeling Defines an Aggressive and Immunomodulatory Subtype of Endometriosis.
Liu J, Han W, Tang J, Wan H, Wang H, Peng J, Ma W, Hu M, Hong L
Aging cell 2026 Apr;25(4):e70463
Aging cell 2026 Apr;25(4):e70463
RUVBL2 Regulates Microglia Metabolic Reprogramming to Mediate Stress Granules Aggregation Exacerbating Postoperative Delirium in Aged Mild Cognitive Impairment Rats.
Zhang L, Wang Z, Yang C, Wang X, Liu X, Zhang H, Liu H, Liao H, Chen J, Wang H
Aging cell 2026 Apr;25(4):e70458
Aging cell 2026 Apr;25(4):e70458
Cancer Cell-Intrinsic Cholesterol Induces Lipid-Associated Macrophage Differentiation via SP1 Palmitoylation to Promote Prostate Cancer Progression.
Peng S, Lin W, Li Z, Zhuang R, Peng S, Li B, Chen B, Luo Y, Ou Y, Zhuang W, Du T, Li K, Huang H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(19):e08588
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(19):e08588
Integrative analysis and experimental validation unveil TNFSF10 as a key PANoptosis inducer driving preeclampsia pathogenesis.
Mei Z, Li L, Chen J, Yang S, Li Y, Li X, Li M, Chen M, Kong R, Zhao Y, Zhao K, McClements L, Zhang H, Liu C
International immunopharmacology 2026 Apr 15;175:116401
International immunopharmacology 2026 Apr 15;175:116401
Altered Atlas of Exercise-Responsive MicroRNAs Revealing miR-29a-3p Attacks Armored and Cold Tumors and Boosts Anti-B7-H3 Therapy.
Mei J, Luo Z, Cai Y, Wan R, Qian Z, Chu J, Sun Y, Shi Y, Jiang Y, Zhang Y, Yin Y, Chen S
Research (Washington, D.C.) 2025;8:0590
Research (Washington, D.C.) 2025;8:0590
A Mesoporous Silica-Based Naringenin Delivery System Promoting Macrophage M2 Polarization in Atherosclerosis.
Ren S, Liu J, Pu H, Wang P, Wu X, Qin J, Liu X, Yin M, Lu X, Li B, Zhao Z
Biomaterials research 2025;29:0248
Biomaterials research 2025;29:0248
Hyperuricemia in ob/ob mice relates to hepatocellular pyruvate metabolism/ xanthine oxidase axis.
Zhang S, Hu S, Tan H, Jia E
PloS one 2025;20(8):e0328794
PloS one 2025;20(8):e0328794
Prussian Blue Nanoparticle-Induced Alteration of the Polarization State of Tumor-Associated Macrophages as a Substantial Antitumor Mechanism Against Oral Squamous Cell Carcinoma (OSCC).
Zhang Z, Sun X, Gao Z, Lv X, Jia H, Huang B, Xia C, Yang X
International journal of nanomedicine 2025;20:10667-10681
International journal of nanomedicine 2025;20:10667-10681
The Human Milk-derived Peptide Drives Rapid Regulation of Macrophage Inflammation Responses in the Neonatal Intestine.
Yuan F, Han X, Huang M, Su Y, Zhang Y, Hu M, Yu X, Jin W, Li Y, Zhang L
Cellular and molecular gastroenterology and hepatology 2025;19(2):101420
Cellular and molecular gastroenterology and hepatology 2025;19(2):101420
Exploring the Therapeutic Mechanism of Jianpi Zhidong Decoction on Tourette Syndrome Based on Proteomics and Network Pharmacology.
Zhang N, Zhang H, Guo J, Ma Y, Bai X, Ma N, Ji X, Meng Y, Li H, Sangwanit T, Shi Y, Zhao J, Li X, Lin J, Cui X
Drug design, development and therapy 2025;19:3139-3158
Drug design, development and therapy 2025;19:3139-3158
TENS alleviates CP/CPPS-related inflammation and pain by modulating Kir2.1-dependent macrophage polarization.
Hong T, Liu X, Chi Z, Liu G, Zhang Y, Lin X, Yao P, Gong Q, Zhang Y, Hong X
Frontiers in immunology 2025;16:1683500
Frontiers in immunology 2025;16:1683500
Reciprocal activation between M1 macrophages and trophoblasts through CXCL9/STAT1/ZEB1/CCL2 axis promotes recurrent spontaneous abortion.
Yan S, Wang X, Wu Q, Ding J, Qiu H
Frontiers in immunology 2025;16:1629370
Frontiers in immunology 2025;16:1629370
Stat3-mediated Th17 pathogenicity induced by periodontitis contributes to cognitive impairment by promoting microglial M1 polarization.
Zhou Y, Xie X, Chen H, Xu L, Qiu C, Shen H, Zhou W, Song Z
Frontiers in immunology 2025;16:1590665
Frontiers in immunology 2025;16:1590665
Wharton's jelly-derived mesenchymal stem cells ameliorate high altitude-induced heart injury by promoting type 2 macrophage polarization via COX2-PGE2 pathway.
Zhang W, Zhao L, Cui J, Zhang Y, Li D, Hong Z, Liu J, Wang S, Zhang N, Li Y, Chen Y
Frontiers in immunology 2025;16:1538046
Frontiers in immunology 2025;16:1538046
Berbamine attenuates hind limb ischemia-reperfusion injury by eliminating lipid ROS and inhibiting p65 nuclear translocation.
Zheng L, Zhao B, Ji R, Zhang Z, Liu Y, Zhao X, Cai J, Qiao T
Frontiers in pharmacology 2025;16:1509860
Frontiers in pharmacology 2025;16:1509860
Ultra-small quercetin-based nanotherapeutics ameliorate acute liver failure by combatting inflammation/cellular senescence cycle.
Feng Y, Zhang X, Li J, Fu S, Xu W, Liu J, Yang Y, Chen T, Zhao Y, Li D, Zhang M, He Y
Theranostics 2025;15(3):1035-1056
Theranostics 2025;15(3):1035-1056
Hsa_circ_0058495-mediated IGF2BP2 ubiquitination and m6A modification of MEKK1 promote the progression of PDAC.
Lv S, Zhang J, Peng X, Liu H, Chu T, Liu Z, Duan K, Guo J, Wang J, Liu Y, Wei F
Theranostics 2025;15(18):9922-9943
Theranostics 2025;15(18):9922-9943
Tremella fuciformis Polysaccharides Alleviate Early Brain Injury in Experimental Subarachnoid Hemorrhage by Inhibiting the KDR-Mediated P38 MAPK/NF-κB Pathway.
Wan YH, Cheng ZJ, Fan LX, Yang DH, Chen BL, Chen XX, Zhu Q
Molecular neurobiology 2025 Sep;62(9):11112-11129
Molecular neurobiology 2025 Sep;62(9):11112-11129
Combining transcriptomics and network pharmacology to reveal the mechanisms of QuZhuoHuaYu decoction ameliorating gouty arthritis.
Tan H, Zhang S, Wang Z, Zhang Z, Zhang J, Jia E
Fitoterapia 2025 Sep;185:106744
Fitoterapia 2025 Sep;185:106744
A Myelin Debris Cleaner for Spinal Cord Injury Recovery: Polycaprolactone / Cell Membrane Assembled Scaffolds.
Zhou Y, Xu T, Zhou Y, Chen N, Wu Z, Yang Z, Yang C, Chen X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(36):e03269
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(36):e03269
METTL14 knockdown augmented the polarization of M2-like macrophages to promote acute myeloid leukemia progression.
Wang M, Xie Z, Tan Y, Zhou Y, Wang S, Zhang P, Li J
Human cell 2025 Sep 30;38(6):168
Human cell 2025 Sep 30;38(6):168
Lactobacillus acidophilus promotes cognitive function recovery via regulating microglial peroxisomal function in cerebral ischemia.
Huang Y, Zhang X, Yu C, Liu Y, Kang H, Liu Y, Ni Y, Xia Y, Jiang Z, Chen J, Zhao K, Han L, Zou X, Wang J, Lei T, Gan C, Zhang H
Cell host & microbe 2025 Sep 10;33(9):1484-1501.e12
Cell host & microbe 2025 Sep 10;33(9):1484-1501.e12
Gut microbiota diversity and metabolomics analysis of curcumin's alleviation of abdominal aortic aneurysm progression.
Cheng S, Hao X, Wang L, Jiang B, Xin S
Molecular and cellular biochemistry 2025 Oct;480(10):5459-5472
Molecular and cellular biochemistry 2025 Oct;480(10):5459-5472
Engineered decellularized tendon hydrogel with sustained zinc ion release orchestrates anti-inflammatory microenvironment and functional regeneration in Achilles tendinopathy.
Gao X, Wu S, Yao Z, Shao Y, Feng J, Yuan Z, Mao H
Materials today. Bio 2025 Oct;34:102104
Materials today. Bio 2025 Oct;34:102104
Columbianadin targets TRIM7 to maintain P2X7 palmitoylation, inhibiting cuproptosis in synovial M2 macrophages.
Li Z, Huang Z, Liao X, Li H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Oct;146:157091
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Oct;146:157091
POSTN-Mediated Interplay of M1 Polarized Macrophage with Tendon-Derived Stem Cells to Drive Traumatic Heterotopic Ossification Formation through PTK7/ATK Signaling?
Liu H, Li X, Li M, Sun Z, Wang X, Li J, Xu B, Chen Q, Fan C, Ruan H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(40):e07951
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(40):e07951
Intratumoral microbiota-driven macrophage reprogramming in pancreatic cancer via Blautia metabolite 6-hydroxyhexanoic acid.
Zhong Y, Zhang D, Ding F, Zhang H, Guo Y, Huang Q, Liu G, Zhang X, Weng S
International immunopharmacology 2025 Oct 30;164:115421
International immunopharmacology 2025 Oct 30;164:115421
Ershen Dan attenuates atherosclerosis by modulating the NOTCH1/NF-κB/NLRP3 signaling pathway to suppress M1 macrophage polarization.
Zhao W, Wang H, Peng S, Wei Q, Zhang L, Li Y, Yang W
Chinese medicine 2025 Oct 23;20(1):178
Chinese medicine 2025 Oct 23;20(1):178
Microglia-Derived Exosomal miR-223-3p Targets the RhoB-NF-κB-CCL11 Axis in Astrocytes and Relieves Neuronal Damage in Subarachnoid Hemorrhage.
Zeng F, Liao Z, Li L, Yang B, Lin J
Neurochemical research 2025 Oct 14;50(5):326
Neurochemical research 2025 Oct 14;50(5):326
ALKBH8-mediated codon-specific translation promotes colorectal tumorigenesis.
Qian Y, Wu C, Wei S, Yan S, Peng J, Yu L, Gao Y, Hou J, Yu W, Chen Z, Zhang J, Gao X
Nature communications 2025 Oct 13;16(1):9075
Nature communications 2025 Oct 13;16(1):9075
Fe-MOF loaded with capmatinib to reverse immunosuppressive microenvironment and inhibit tumor metastasis after radiofrequency ablation.
Zhao J, Lei L, Zeng C, Zhou X, Ding J, Dai W, Jiang A, Zou S, Jin Q, Tang Z
Journal of nanobiotechnology 2025 Oct 10;23(1):648
Journal of nanobiotechnology 2025 Oct 10;23(1):648
The Crosstalk Between Sepsis-Associated Encephalopathy and Alzheimer's Disease: Identifying Potential Biomarkers and Therapeutic Targets for Cognition.
Wang Z, Zhang Z, Shi J, Zhao R
Molecular neurobiology 2025 Nov;62(11):13999-14014
Molecular neurobiology 2025 Nov;62(11):13999-14014
An aptamer specifically targeting mCRP ameliorates experimental arthritis.
Wang Z, Xie D, Zhu P, Guo J, Cao C, Du Y, Lu A, Liang C
Journal of orthopaedic translation 2025 Nov;55:228-244
Journal of orthopaedic translation 2025 Nov;55:228-244
(20S)-protopanaxatriol attenuates Ang II-induced renal injury via PTPN1-mediated AMPK/mTOR signaling pathway.
Zhao R, Wang Z, Liu C, Zhang L, Zhang M, Du H, Yang G, Sun H, Liu W, Yan S, Wang M
Journal of ginseng research 2025 Nov;49(6):652-662
Journal of ginseng research 2025 Nov;49(6):652-662
Sinomenine alleviates gouty inflammation by inhibiting macrophage M1 polarization and neutrophil extracellular trap formation.
Zhang S, Tan H, Zhang Z, Wang Z, Zhang C, Zhang J, Jia E
Naunyn-Schmiedeberg's archives of pharmacology 2025 Nov;398(11):15791-15805
Naunyn-Schmiedeberg's archives of pharmacology 2025 Nov;398(11):15791-15805
Treadmill exercise alleviates STING-mediated microglia pyroptosis and polarization via activating mitophagy post-TBI.
Chen J, Zhu T, Yang X, Yang Z, Shen M, Gu B, Wang D, Zhang Y, Zhang M, Sun S, Yu J, Yan C
Free radical biology & medicine 2025 Nov;239:155-176
Free radical biology & medicine 2025 Nov;239:155-176
Decoupling Half-Process Assisted Mitochondrial Transplantation via Self-Stripping pHLIP Boosts Macrophages Reprogramming for Inflammation Resolution.
He P, Wu X, Li M, Liu K, Chen Y, Zhang Q, Cheng H, Li Y, Yang S
Small (Weinheim an der Bergstrasse, Germany) 2025 Nov;21(45):e07970
Small (Weinheim an der Bergstrasse, Germany) 2025 Nov;21(45):e07970
AMPK upregulates SOCS1 to promote TFEB nuclear transfer, enhances autophagy, inhibits macrophage M1 polarization and relieves acute lung injury.
Nie W, Gong C, Liu Y, Yang J, Dai Q, Liao Y, Li F
Molecular immunology 2025 Nov;187:240-253
Molecular immunology 2025 Nov;187:240-253
Inhibition of Macrophage ARID3A Alleviates Myocardial Ischemia-Reperfusion Injury After Heart Transplantation by Reducing THBS1/CD47 Signaling-Mediated Neutrophil Extracellular Traps Formation.
Tian H, Xiong Y, Zhan J, Lu Z, Zhang Y, Leng Y, Huang Q, Xia Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(44):e09952
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(44):e09952
Sleep Deprivation Aggravates Periodontitis Through Trigeminal-Periodontal Neuroimmune Pathway Mediated by the AChE-ACh-α7nAChR Axis.
Liu K, Huang Q, Yang M, Huang Z, Tuerhong K, Zu Y, Xie Y, Hu X, Zhang Q, He P, Huang N, Zhang R, Li Y, Yang S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(43):e00945
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(43):e00945
Fatty acid-binding protein 4 drives microglia-mediated neuroinflammation through promoting S100A9 expression and lipid droplet accumulation after intracerebral hemorrhage.
He J, Qin Z, Liu H, Cai Y, Wu H, Wang T, Hu Q, Xu Y, Yang P, Wu X, Qu Y, Guo W
Journal of neuroinflammation 2025 Nov 7;22(1):263
Journal of neuroinflammation 2025 Nov 7;22(1):263
Oral Multi-Enzymatic Manganese-Carbon Dots Alleviate Sepsis-Associated Lung Injury via the Gut-Lung Axis.
Peng L, Song H, Shi H, Wu L, Ma Y, Fan X, Wu M, Duan L, Li Z, Yuan H
ACS nano 2025 Nov 4;19(43):37758-37782
ACS nano 2025 Nov 4;19(43):37758-37782
Urolithin B promotes the functional recovery of spinal cord injury by alleviating neuroinflammation via the inhibition of NLRP3 signaling pathway.
Su Y, Wang H, Yang W, Zhang S, Liu F, Han K, Guan F, Ma S, Cui Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157331
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157331
11-keto-β-boswellic acid and Z-guggulsterone suppress HMGB1/TLR4 pathway activity and modulate microglial polarization to remodel perineuronal nets after nerve injury.
Liao Y, Yang L, Ding Y, Guo C, Hu J, Xu X, Zhu H, Yang J, Zhao M
Journal of advanced research 2025 Nov 2;
Journal of advanced research 2025 Nov 2;
Application of Dental Pulp Stem Cell-Derived Intracellular Vesicles for Diabetic Wound Healing.
Pang P, Liu Y, Song H, Ye Z, Zhou H, Zhang R, Kumeria T, She W, Xu C, Mei PL, He Y, Ye Q
Diabetes 2025 Nov 1;74(11):2060-2074
Diabetes 2025 Nov 1;74(11):2060-2074
FGF21-loaded M2 macrophage-derived exosomes attenuate sepsis-induced lung injury by regulating M2 macrophage polarization and glycolysis.
Wu F, Zhang Y, Tang Y, Kang Y, Li Y, Hu X, Liu J, Tian X, Lu Z
Life sciences 2025 Nov 1;380:123932
Life sciences 2025 Nov 1;380:123932
Th22 cells promote the transition from homeostatic to reactive microglia in diabetic encephalopathy.
Yu SX, Yu HD, Wang YF, Yao TF, Lv SZ, Wang YC, Li JQ, Liu WQ, Ding JY, Liu XZ, Zuo ZF, Liu WP
Acta diabetologica 2025 May;62(5):633-650
Acta diabetologica 2025 May;62(5):633-650
An ultrasound-driven PLGA/Zn-KNN hybrid piezoelectric scaffold with direct and immunoregulatory antibacterial activity for bone infection.
Zheng Y, Wang S, Jin W, Li Z, Yang G, Li X, Li N, Wang Y, Sheng F, Song Z
Bioactive materials 2025 May;47:295-312
Bioactive materials 2025 May;47:295-312
Restoring tendon microenvironment in tendinopathy: Macrophage modulation and tendon regeneration with injectable tendon hydrogel and tendon-derived stem cells exosomes.
Li D, Li S, He S, He H, Yuan G, Ma B, Zhang Y, Yuan C, Liu Z, Deng Z, Xu J
Bioactive materials 2025 May;47:152-169
Bioactive materials 2025 May;47:152-169
Three polysaccharides from Roughhaired Holly Root with immune-enhancing activity via activation of TLR receptor.
Huang R, Huang X, He W, Zhong Z, Li H, Li Q
International journal of biological macromolecules 2025 May;308(Pt 3):142266
International journal of biological macromolecules 2025 May;308(Pt 3):142266
Electroacupuncture alleviates diesel exhaust particles-induced inflammatory response in lung through dopamine inhibition of NLRP3 signaling pathway.
Xie Y, Han J, Wang Q, Fang X, Pan B, Han D, Li J, Shao W, Hong X, Tu W, Geng W, Li W, Tian Z, Chen R, Xu Y, Kan H
Ecotoxicology and environmental safety 2025 May;296:118184
Ecotoxicology and environmental safety 2025 May;296:118184
Mg(2+)-Loaded Black Phosphorus Nanosheet Protects against Cerebral Ischemic Injury through Anti-Oxidative and Anti-Inflammatory Effects.
Wang M, Xia X, Li Y, Zhang K, Cheng X, Wen X, Zhao L, Guo X, Song F, Cheng A
Advanced healthcare materials 2025 May;14(13):e2500929
Advanced healthcare materials 2025 May;14(13):e2500929
GTS-21 alleviates sepsis-induced atrial fibrillation susceptibility by modulating macrophage polarization and Neuregulin-1 secretion.
Zhou J, Wu K, Ma Y, Zhu J, Zhou Y, Zhang Z, Li F, Zeng G, Li S, Tan S, Zhang Y, Wan C, Tu T, Lin Q, Liu Q
International immunopharmacology 2025 May 8;154:114561
International immunopharmacology 2025 May 8;154:114561
L-Kynurenine regulates immune response in ICIs-associated myocarditis via JAK/STAT pathway.
He X, Zhang J, Zhang Y, Li H, Chen Y, Zhang H, Pan J, Zhou Y, Zhang S, Cheng L
International immunopharmacology 2025 May 27;156:114676
International immunopharmacology 2025 May 27;156:114676
Astragaloside IV prevents liver fibrosis by blocking glycolysis-mediated macrophage M1 polarization.
Hu Y, Kuang M, Song H, Tan Y, Zhou F, Pei G, Jiao L
European journal of pharmacology 2025 May 15;995:177353
European journal of pharmacology 2025 May 15;995:177353
Microneedle-mediated hypoxic extracellular vesicle-encapsulated selenium nanoparticles delivery to treat androgenetic alopecia.
Jing S, Liu Y, Wang B, Zhou H, Zhang H, Siwakoti P, Qu X, Ye P, He Y, Kumeria T, Ye Q
Journal of controlled release : official journal of the Controlled Release Society 2025 May 10;381:113597
Journal of controlled release : official journal of the Controlled Release Society 2025 May 10;381:113597
Response to: Correspondence on 'Unveiling inflammatory and prehypertrophic cell populations as key contributors to knee cartilage degeneration in osteoarthritis using multi-omics data integration' by Fan et al.
Fan Y, Bian X, Zhang D, Sun S
Annals of the rheumatic diseases 2025 Mar;84(3):e12-e15
Annals of the rheumatic diseases 2025 Mar;84(3):e12-e15
An active shrinkage and antioxidative hydrogel with biomimetic mechanics functions modulates inflammation and fibrosis to promote skin regeneration.
Zhang T, Zhong XC, Feng ZX, Lin XY, Chen CY, Wang XW, Guo K, Wang Y, Chen J, Du YZ, Zhuang ZM, Wang Y, Tan WQ
Bioactive materials 2025 Mar;45:322-344
Bioactive materials 2025 Mar;45:322-344
Trimethylamine N-oxide aggravates human aortic valve interstitial cell inflammation by regulating the macrophages polarization through a N6-methyladenosine-mediated pathway.
Wen L, Lin X, Hu D, Li J, Xie K, Li S, Su S, Duan X, Zhong G, Lin Y, Chen Y, Xu T, Zeng Q
Atherosclerosis 2025 Mar;402:119109
Atherosclerosis 2025 Mar;402:119109
A kidney protection nanoparticle based on Alpinia oxyphylla fructus polysaccharide by modulating macrophage polarization.
Deng D, Zhang R, Wu J, Wang L, Zhang Q, Zhang J, Tan Y, Chen K, Li Y
International journal of biological macromolecules 2025 Mar;292:139367
International journal of biological macromolecules 2025 Mar;292:139367
Rapid angiogenic hydrogel nanofiber scaffold promotes random flap regeneration and modulates inflammation.
Liang J, Zou Y, Ju H, Lv Y
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2025 Mar-Apr;33(2):e70028
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2025 Mar-Apr;33(2):e70028
M2 macrophages promote PKM2 production in fibroblasts to alleviate UVB-induced photoaging.
Jia S, Shi N, Lu M, Wang X, Qi Y, Wang X, Zhao J, Jiang D
Cell cycle (Georgetown, Tex.) 2025 Mar-Apr;24(5-8):86-102
Cell cycle (Georgetown, Tex.) 2025 Mar-Apr;24(5-8):86-102
Janus hydrogel microrobots with bioactive ions for the regeneration of tendon-bone interface.
Ding Z, Cai Y, Sun H, Rong X, Ye S, Fan J, Lai Y, Liang Z, Huang C, Li P, Fu X, Wang L, Tang G, Zhou Z, Luo Z
Nature communications 2025 Mar 4;16(1):2189
Nature communications 2025 Mar 4;16(1):2189
Tremella polysaccharide microneedles loaded with magnetic dental pulp stem cell intracellular vesicles used for androgenic alopecia.
Liu Y, Zhou H, Pang P, Liu Y, Situ J, Wang J, He Y, Ye Q
Stem cell research & therapy 2025 Mar 31;16(1):161
Stem cell research & therapy 2025 Mar 31;16(1):161
The role of Morin in attenuating atherosclerosis via STAT1 pathway inhibition.
Ji X, Dong Q, Li W, Luo W, Zhou N, Li H, Yang X
Biochemical and biophysical research communications 2025 Mar 25;754:151537
Biochemical and biophysical research communications 2025 Mar 25;754:151537
Corilagin enhances wound healing by modulating the macrophage phenotype in diabetic mice.
Li Y, Yu S, Zeng J, Zhou S, Cui X, Zhou J, Zhang P
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Mar 15;39(5):e70439
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Mar 15;39(5):e70439
Topical transdermal administration of lenalidomide nanosuspensions-based hydrogels against melanoma: In vitro and in vivo studies.
Zhang M, Qiu H, Han Z, Ma Y, Hou J, Yuan J, Jia H, Zhou M, Lu H, Wu Y
International journal of pharmaceutics: X 2025 Jun;9:100316
International journal of pharmaceutics: X 2025 Jun;9:100316
A novel strategy for bone defect repair: Stromal cell-derived factor 1α sustained-release acellular fish scale scaffolds combined with injection of bone marrow mesenchymal stem cells promote bone regeneration.
Su S, Bai J, Wang R, Gao S, Zhou R, Zhou F
Materials today. Bio 2025 Jun;32:101759
Materials today. Bio 2025 Jun;32:101759
CuATSM Enhances Wound Repair Without Scarring via Hippo/YAP Signalling Pathway to Reduce Ferroptosis and Macrophage Polarisation.
Tang Y, Ye J, Xu T, Sun Y, Meng W, Zhu L, Jia Z, Wu Q, Chen D, Wu F
Journal of cellular and molecular medicine 2025 Jun;29(12):e70590
Journal of cellular and molecular medicine 2025 Jun;29(12):e70590
Ultraviolet-treated riboflavin alleviates atopic dermatitis by inhibiting NLRP3 inflammasome activation and M1 macrophage polarization via histone lactylation.
Ge S, Qiu B, Liu R, Sun L, Yang L, Chen X, Tao H, Yang W, Yu Y, Wang D
Biochemical pharmacology 2025 Jun;236:116879
Biochemical pharmacology 2025 Jun;236:116879
Ultrasound-responsive taurine lipid nanoparticles attenuate oxidative stress and promote macrophage polarization for diabetic wound healing.
Luo Z, Zheng S, Hu Z, Li P, Zeng J, Lu Y, Ali M, Chen Z, Wang Q, Qi F
Free radical biology & medicine 2025 Jun;233:302-316
Free radical biology & medicine 2025 Jun;233:302-316
TREM2 activation reduces white matter injury via PI3K/Akt/GSK-3β signalling after intracerebral haemorrhage.
Zhang Y, Shi Y, Wang L, Li Z, Wang Y, Yan J, Sun X, Luo Q, Li L
British journal of pharmacology 2025 Jun;182(11):2542-2559
British journal of pharmacology 2025 Jun;182(11):2542-2559
Gallic acid promotes M2 macrophage polarization through mitochondrial oxidative phosphorylation in periodontitis.
Zhang R, Yang W, Li K, Zhang X, Liu J, Ai L
Archives of oral biology 2025 Jun;174:106237
Archives of oral biology 2025 Jun;174:106237
The microglial state transition as a novel mechanism by which fresh Baihe Dihuang decoction prevents depression by regulating SIRT1/HMGB1 signaling.
Cao LH, Wang ZZ, Zhao H, Tian S, He HJ, Miao JX, Huang SN, Wang XY, Song YG, Kang L, Wang HY, Wang C, Bai M, Gao S, Miao MS
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156718
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156718
An Intelligent and Conductive Hydrogel with Multiresponsive and ROS Scavenging Properties for Infection Prevention and Anti-Inflammatory Treatment Assisted by Electrical Stimulation for Diabetic Wound.
Zhang T, Meng Z, Yu H, Ding P, Kai T
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jun;12(23):e2500696
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jun;12(23):e2500696
PINK1 affects mitochondrial oxidative phosphorylation by regulating MFN2 to alleviate diabetic kidney disease.
Pei X, Liu J, Wei Y, Zhu Y, Li Y, Wang Q, Zhuang L, Jin G
International immunopharmacology 2025 Jun 5;157:114786
International immunopharmacology 2025 Jun 5;157:114786
Exercise-induced irisin ameliorates cognitive impairment following chronic cerebral hypoperfusion by suppressing neuroinflammation and hippocampal neuronal apoptosis.
Xiao W, Yang Y, Bai L, Yang P, Li R, Yang D, Li F, Quan L, Liang Q, Yan Y, Qi T, Liang F
Journal of neuroinflammation 2025 Jun 28;22(1):168
Journal of neuroinflammation 2025 Jun 28;22(1):168
miR-29a nanoparticles improve chronic insomnia by regulating microglia activation and hippocampal neuronal cell pyroptosis through PER2/NF-κB axis.
Hou D, Hu Y, Li H, Yang G
International immunopharmacology 2025 Jun 26;159:114882
International immunopharmacology 2025 Jun 26;159:114882
Integrative PANoptosis gene profiling reveals prognostic and therapeutic insights in prostate cancer.
Wang Y, Du Y, Wang X, Yu J, Gu Q, Yuan G, Zhu Y, Gu L, Ouyang J
Biomolecules & biomedicine 2025 Jun 19;26(7):1162-79
Biomolecules & biomedicine 2025 Jun 19;26(7):1162-79
Tumor-derived exosomal miR-425-5p and miR-135b-3p enhance colorectal cancer progression through immune suppression and vascular permeability promotion.
Feng CZ, Zhong SQ, Ye SW, Zheng Z, Sun H, Zhou SH
World journal of gastrointestinal oncology 2025 Jun 15;17(6):106161
World journal of gastrointestinal oncology 2025 Jun 15;17(6):106161
Cannabinoid Receptor-2 Alleviates Sepsis-Induced Neuroinflammation by Modulating Microglia M1/M2 Subset Polarization Through Inhibiting Nogo-B Expression.
Chen S, Li Z, Yang L, Xu Z, Liu A, He Q, Xiao F, Zhan J
Molecular neurobiology 2025 Jul;62(7):9258-9270
Molecular neurobiology 2025 Jul;62(7):9258-9270
The Polarization of Macrophages Regulated by KCNG3 via the Activation of ASK1 Mediated by Potassium Ion Efflux.
Zhang S, Xin Y, Yang Y, Zhang Y, Geng J
Cell biology international 2025 Jul;49(7):810-823
Cell biology international 2025 Jul;49(7):810-823
Hyaluronic acid methacryloyl hydrogel with sustained IL-10 release promotes macrophage M2 polarization and motor function after spinal cord injury.
Wang Z, Li D, Wang Y, Yuan P, Zhang W, Zhang Y, He F, Yang J, Bi H, Duan H
Journal of biomaterials applications 2025 Jul;40(1):3-19
Journal of biomaterials applications 2025 Jul;40(1):3-19
Akkermansia muciniphila relieves inflammatory response in DSS-induced ulcerative colitis in mice through regulating macrophage polarization via SCFAs-SLC52A2/FFAR2 pathway.
Zhang L, Wang J, Xu Y, Wei K, Lin W, Hu H, Liu Y
Naunyn-Schmiedeberg's archives of pharmacology 2025 Jul;398(7):8695-8711
Naunyn-Schmiedeberg's archives of pharmacology 2025 Jul;398(7):8695-8711
Photosensitive Biomimetic Nanomedicine-Mediated Recombination of Adipose Microenvironments for Antiobesity Therapy.
Song M, Wang L, Tian J, Qin Y, Zhang W, Chen S, Liu C
Advanced materials (Deerfield Beach, Fla.) 2025 Jul;37(30):e2417377
Advanced materials (Deerfield Beach, Fla.) 2025 Jul;37(30):e2417377
DPSCs modulate synovial macrophage polarization and efferocytosis via PINK1/Parkin-dependent mitophagy.
Ma J, Wang X, Sun D, Chen J, Zhou L, Zou K, Ni X, Jin H, Lin J
Stem cell research & therapy 2025 Jul 9;16(1):356
Stem cell research & therapy 2025 Jul 9;16(1):356
Colchicine alleviates ischemic white matter lesions and cognitive deficits by inhibiting microglia inflammation via the TAK1/MAPK/NF-κB signaling pathway.
Liu Y, Zhai Y, Ma L, Wang Z, Wang J, Hu B, Tang Y
Behavioural brain research 2025 Jul 26;490:115619
Behavioural brain research 2025 Jul 26;490:115619
Wenxia Changfu formula inhibits Lewis lung cancer metastasis by reprogramming tumor-associated macrophages through the PPAR-γ/CD36 pathway.
Yin X, Sun X, Li A, Ruan J, Niu H, Zhou Y, Chen G, Guo J, He Q, Ji X
Journal of ethnopharmacology 2025 Jul 24;351:120103
Journal of ethnopharmacology 2025 Jul 24;351:120103
Author Correction: Fibroblast derived C3 promotes the progression of experimental periodontitis through macrophage M1 polarization and osteoclast differentiation.
Ren F, Zheng S, Luo H, Yu X, Li X, Song S, Bu W, Sun H
International journal of oral science 2025 Jul 2;17(1):53
International journal of oral science 2025 Jul 2;17(1):53
Activation of Hippocampal ACE2 Prevents the Dysbiosis-induced Depression-like Behavior in Mice by Enhanced Neurogenesis and Neuroprotection via Mas Receptor.
Takahashi K, Nakagawasai O, Kurokawa K, Miyagawa K, Mochida-Saito A, Takeda H, Tsuji M
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2025 Jul 18;20(1):71
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2025 Jul 18;20(1):71
Agrocybe cylindracea Polysaccharides Ameliorate DSS-Induced Colitis by Restoring Intestinal Barrier Function and Reprogramming Immune Homeostasis via the Gut-Liver Axis.
Atta A, Naveed M, Rahman MU, Alioui Y, Ansari I, Ali S, Ghaleb E, Farooqui NA, Abusidu M, Xin Y, Feng B
International journal of molecular sciences 2025 Jul 16;26(14)
International journal of molecular sciences 2025 Jul 16;26(14)
Poldip2 Aggravates inflammation in diabetic retinopathy by impairing mitophagy via the AMPK/ULK1/Pink1 pathway.
Lin S, Ji Z, Gao J, Fan J, Hou J, Liu S, Wang C, Chen K, Tao L, Jiang Z
Life sciences 2025 Jul 15;373:123681
Life sciences 2025 Jul 15;373:123681
Spi1 aggravates neuropathic pain by modulating Clec7a-mediated neuroinflammation and microglial phagocytosis.
Xu Y, Liu X, Chen H, Zhao Y, Zhao Y, Xie Y, Pang J, Zeng H, Zeng Y, Peng W, Zheng M, Wu W
The journal of headache and pain 2025 Jul 10;26(1):158
The journal of headache and pain 2025 Jul 10;26(1):158
Multilayered hydrogel scaffold construct with native tissue matched elastic modulus: A regenerative microenvironment for urethral scar-free healing.
Jin Y, Wang Y, Yang R, Fang W, Zhang K, Liu M, Wang Y, Yang M, Fu Q
Biomaterials 2025 Jan;312:122711
Biomaterials 2025 Jan;312:122711
Carboxymethylated yeast β-glucan: Biological activity screening in zebrafish, sprayable hydrogel preparation, and wound healing study in diabetic mice.
Xu C, Zhang Y, Li H, Zhang Z, Sheng W, Zhang S, Li P, Zhang X, Li X, Lin H, Duan H, Guan S, Wang L
International journal of biological macromolecules 2025 Jan;285:138178
International journal of biological macromolecules 2025 Jan;285:138178
The Anti-Inflammatory Effects of Formononetin, an Active Constituent of Pueraria montana Var. Lobata, via Modulation of Macrophage Autophagy and Polarization.
Xu L, Zhou S, Li J, Yu W, Gao W, Luo H, Fang X
Molecules (Basel, Switzerland) 2025 Jan 6;30(1)
Molecules (Basel, Switzerland) 2025 Jan 6;30(1)
Sodium butyrate regulates macrophage polarization by TGR5/β-arrestin2 in vitro.
Liu M, Xie WJ, Zhang X, Wu W, Li G, Wang L
Molecular medicine (Cambridge, Mass.) 2025 Jan 29;31(1):31
Molecular medicine (Cambridge, Mass.) 2025 Jan 29;31(1):31
Extracellular Matrix-Mimicking Hydrogel with Angiogenic and Immunomodulatory Properties Accelerates Healing of Diabetic Wounds by Promoting Autophagy.
Pan Y, Li Y, Zhou X, Luo J, Ding Q, Pan R, Tian X
ACS applied materials & interfaces 2025 Jan 22;17(3):4608-4625
ACS applied materials & interfaces 2025 Jan 22;17(3):4608-4625
sB7-H4 is a diagnostic biomarker in epithelial ovarian cancer and correlates to platinum resistance.
Zhou Y, Tian J, Shen Y, Liang H, Chen Y, Wang J, Gu Y
Clinical and experimental immunology 2025 Jan 21;219(1)
Clinical and experimental immunology 2025 Jan 21;219(1)
Mesoporous Prussian blue nanoparticle neuroconduit for the biological therapy targeting oxidative stress reduction, inflammation inhibition, and nerve regeneration.
Zhu J, Zhang Y, Sun Y, Yu F, Lu Y, Hu Q, Guo J, Zhang H, Chen T, Lian F, Wang J, Li X, Xiao J
Journal of nanobiotechnology 2025 Jan 2;23(1):1
Journal of nanobiotechnology 2025 Jan 2;23(1):1
Zinc-induced photocrosslinked konjac glucomannan/glycyrrhizic acid hydrogel promotes skin wound healing in diabetic mice through immune regulation.
Li J, Wu D, Su Z, Guo J, Cui L, Su H, Chen Y, Yu B
Carbohydrate polymers 2025 Jan 15;348(Pt A):122780
Carbohydrate polymers 2025 Jan 15;348(Pt A):122780
ALKBH5 alleviates lower extremity arteriosclerosis by regulating ITGB1 demethylation and influencing macrophage polarization.
Guan Z, Wang X, Xu C, Lu R
Heliyon 2025 Jan 15;11(1):e41495
Heliyon 2025 Jan 15;11(1):e41495
PTX3 impairs granulosa cell function by promoting the secretion of inflammatory cytokines in M1 macrophages via the JAK pathway.
Chen Y, Luo X, Li Y, Liu L, Liu Z, Tan Y, Chen Y
Steroids 2025 Feb;214:109541
Steroids 2025 Feb;214:109541
Coptisine improves LPS-induced anxiety-like behaviors by regulating the Warburg effect in microglia via PKM2.
Qi Y, Zhao X, Wu W, Wang N, Ge P, Guo S, Lei S, Zhou P, Zhao L, Tang Z, Duan J, Yang N, Guo R, Dong Y, Chai X, Zhang Q, Snijders AM, Zhu H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2025 Feb;183:117837
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2025 Feb;183:117837
Manipulation of Surface Potential Distribution Enhances Osteogenesis by Promoting Pro-Angiogenic Macrophage Polarization via Activation of the PI3K-Akt Signaling Pathway.
Cui Q, Zheng X, Bai Y, Guo Y, Liu S, Lu Y, Liu L, Song J, Liu Y, Heng BC, You F, Xu M, Deng X, Zhang X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(8):e2414278
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(8):e2414278
Hydroxysafflor yellow A attenuates the inflammatory response in cerebral ischemia-reperfusion injured mice by regulating microglia polarization per SIRT1-mediated HMGB1/NF-κB signaling pathway.
Yao M, Liu Y, Meng D, Zhou X, Chang D, Li L, Wang N, Huang Q
International immunopharmacology 2025 Feb 6;147:114040
International immunopharmacology 2025 Feb 6;147:114040
Blocking the CCL5/CCL7-CCR1 axis regulates macrophage polarization through NF-κB pathway to alleviate the progression of osteoarthritis.
Xu H, He Y, Chen S, Meng C, Liu Q, Huang XJ, You HB
International immunopharmacology 2025 Feb 6;147:114027
International immunopharmacology 2025 Feb 6;147:114027
hBMSC-EVs alleviate weightlessness-induced skeletal muscle atrophy by suppressing oxidative stress and inflammation.
Chang M, Liu R, Chen B, Xu J, Wang W, Ji Y, Gao Z, Liu B, Yao X, Sun H, Xu F, Shen Y
Stem cell research & therapy 2025 Feb 4;16(1):46
Stem cell research & therapy 2025 Feb 4;16(1):46
Hepatic Abnormal Secretion of Apolipoprotein C3 Promotes Inflammation in Aortic Dissection.
Zhuang X, Zarif M, Shen Y, Zhang Z, He J, Xie L, Wu Q, Lin X, Chen K, Tian Y, Lin Y, Zhang Y, Cai Z, Qiu Z, Chen L
Journal of the American Heart Association 2025 Feb 4;14(3):e037172
Journal of the American Heart Association 2025 Feb 4;14(3):e037172
LDHA-mediated glycolysis in stria vascularis endothelial cells regulates macrophages function through CX3CL1-CX3CR1 pathway in noise-induced oxidative stress.
Yi Y, Wu MY, Chen KT, Chen AH, Li LQ, Xiong Q, Wang XR, Lei WB, Xiong GX, Fang SB
Cell death & disease 2025 Feb 3;16(1):65
Cell death & disease 2025 Feb 3;16(1):65
ITIH5-mediated fibroblast/macrophage crosstalk exacerbates cardiac remodelling after myocardial infarction.
Wu Y, Meng L, Zhan S, Li M, Huang J, Chen X, Chen L, Gao X, Chen H, Chen H, Zhong Y, Xu L, Xu Y
Journal of translational medicine 2025 Feb 24;23(1):224
Journal of translational medicine 2025 Feb 24;23(1):224
Exosomes from adipose-derived stem cells accelerate wound healing by increasing the release of IL-33 from macrophages.
Wang Y, Ding H, Bai R, Li Q, Ren B, Lin P, Li C, Chen M, Xu X
Stem cell research & therapy 2025 Feb 21;16(1):80
Stem cell research & therapy 2025 Feb 21;16(1):80
Dapagliflozin alleviated seizures and cognition impairment in pilocarpine induced status epilepticus via suppressing microglia-mediated neuroinflammation and oxidative stress.
Liu Y, Yu Y, Chen C, Wu X, Zheng Q, Zhang X, Ye L, Zhang C, Feng Z
International immunopharmacology 2025 Feb 20;148:114117
International immunopharmacology 2025 Feb 20;148:114117
Intelligent sequential degradation hydrogels by releasing bimetal-phenolic for enhanced diabetic wound healing.
Zhang Y, Tang Z, Chen L, Yang M, Zeng Y, Bai X, Zhang B, Zhou J, Zhang W, Tang S
Journal of controlled release : official journal of the Controlled Release Society 2025 Feb 10;378:961-981
Journal of controlled release : official journal of the Controlled Release Society 2025 Feb 10;378:961-981
Bulk and Single-cell transcriptomic profiling identifies C1QA as an Immune-Associated hub genes in graves' ophthalmopathy.
Li LN, Zheng ZJ, Wu JM, Li SX, Cai MY, Zou MC
Endocrine 2025 Dec;90(3):1350-1368
Endocrine 2025 Dec;90(3):1350-1368
ACOD1/Itaconate regulates trophoblast function through the PI3K/Akt/FOLR1 axis to participate in the pathogenesis of recurrent spontaneous abortion.
Feng T, Wu S, Fang J, Ding J, Shen F, Yang J
Biochemical pharmacology 2025 Dec;242(Pt 3):117405
Biochemical pharmacology 2025 Dec;242(Pt 3):117405
A study on the establishment of a traumatic brain injury model of tree shrews and the observation of neuroinflammatory responses.
Yu W, Yang L, Zhang X, Zhang J, Zhang J, Wang L, Huang Y, Hong S, Chen L, Wu H, Li J
IBRO neuroscience reports 2025 Dec;19:912-918
IBRO neuroscience reports 2025 Dec;19:912-918
Synthesis and evaluation of lansiumamide B analogues to ameliorate acute lung injury by reducing oxidative stress and inflammation via Keap1/Nrf2/NF-κB pathway.
Song L, Li M, Li J, Liu L, Luo X, Wang J, Wu X, Huang B, Zhang G, Yao H
European journal of medicinal chemistry 2025 Dec 5;299:118052
European journal of medicinal chemistry 2025 Dec 5;299:118052
(R)-Bambuterol attenuates DSS-induced chronic colitis by suppressing inflammation, repairing intestinal barrier, and modulating gut microbiota and serum metabolomic profile.
Deng L, Tian L, Su D, Xie J, Qian Y, Li Y, Zhang S, Wang S, Liu Z
European journal of pharmacology 2025 Dec 5;1008:178346
European journal of pharmacology 2025 Dec 5;1008:178346
The Role of Chaf1b in Maintaining Glioma Stem Cell Stemness and Regulating Microglial Polarization.
He YL, Niu L, Wang C, Liao ZP, Liu K, Gao S, Du AC, Liu WG, Jia J, Zhang YB, Yin H, Yuan GQ, Pan YW
The Journal of neuroscience : the official journal of the Society for Neuroscience 2025 Dec 3;45(49)
The Journal of neuroscience : the official journal of the Society for Neuroscience 2025 Dec 3;45(49)
Trained immunity attenuated acute lung injury by activating alveolar macrophages via AKT2-PDK1 axis-mediated metabolic reprogramming.
Sun Z, Meng H, Wang X, Guo X, He W, Zhou Y, Wang Z, Li Z, Li X, Wang Y
Journal of translational medicine 2025 Dec 23;23(1):1412
Journal of translational medicine 2025 Dec 23;23(1):1412
Denosumab attenuates knee osteoarthritis progression by inhibiting synovial inflammation via the RANK/TRAF6/FSTL1 signalling.
Hu Y, Chen W, Lan S, Ming C, Xu D, Li H, Xu H, Shi D, Liu W, Dai Z, Wang J, He Z, Xu W, Shao Z, Liu Y, Tian H, Tong W
Nature communications 2025 Dec 17;16(1):11394
Nature communications 2025 Dec 17;16(1):11394
Antigen B from Echinococcus granulosus regulates autophagy-mediated macrophage polarization to alleviate immune thrombocytopenia.
Song HC, Li DL, Wang JJ, Jiao HJ, Li MW, Zhao L, Yang XH, Yan M
Parasites & vectors 2025 Dec 15;19(1):38
Parasites & vectors 2025 Dec 15;19(1):38
Fennel essential oil and its nanoemulsion modulate macrophage-mediated inflammatory responses and promote pressure ulcer healing.
Luo Z, Zeng L, Zhao Z, Zheng Y, Wan D
International immunopharmacology 2025 Dec 10;167:115631
International immunopharmacology 2025 Dec 10;167:115631
Pathology-inspired collagen-binding thermosensitive micelle drops enable prolonged and efficient treatment of fungal keratitis.
Cai M, Zhong H, Wang X, Li L, Zhou X, Wang Y, Hua X, Guo S, Yuan X
Bioactive materials 2025 Aug;50:396-413
Bioactive materials 2025 Aug;50:396-413
Synergistic microglial modulation by laminarin-based platinum nanozymes for potential intracerebral hemorrhage therapy.
Guo X, Zheng Q, Gao W, Xiao Y, Shi L, Lin F, Xiong Y, Zhang Y, Xu Q, Wang L, He S, Zheng F
Biomaterials 2025 Aug;319:123212
Biomaterials 2025 Aug;319:123212
Mechanically-adaptive Janus hydrogel enhances scarless tendon healing with tissue-adhesion prevention.
Tan L, Wang Y, Huyan C, Li M, Liu D, Liu M, Luo Z, Cai K, Hu Y
Acta biomaterialia 2025 Aug;202:170-192
Acta biomaterialia 2025 Aug;202:170-192
MDL800, a SIRT6 activator, mitigates neuroinflammation-induced retinal damage by modulating microglial M1/M2 polarization in experimental glaucoma.
Hu F, Zhang D, Wu J
Cellular signalling 2025 Aug;132:111832
Cellular signalling 2025 Aug;132:111832
COG1410 Alleviated Chronic Sleep Deprivation-Induced Memory Loss by Regulating Microglial Phagocytosis and Inhibiting Hippocampal Inflammation.
Wu P, Fu C, Chen M, Wu F, He W, Luo Q, Wang H, Li Y
ACS chemical neuroscience 2025 Aug 6;16(15):2921-2934
ACS chemical neuroscience 2025 Aug 6;16(15):2921-2934
Exosomal miR-218 secreted from endothelial progenitor cells mitigates acute lung injury in sepsis mice by inhibiting HMGA1 in alveolar macrophages.
Liang G, Zeng M, Wang Q, Wang W, Liu J, Gao M, He Z
Stem cell research & therapy 2025 Aug 6;16(1):431
Stem cell research & therapy 2025 Aug 6;16(1):431
Growth differentiation factor 11 attenuates sepsis-associated acute kidney injury by reducing inflammation and coagulation via PGC-1α/Nrf2 activation.
Wang HW, Wu MM, Zhu MM, Qin YY, Wang KQ, Wu CY, Zhang RR, Wang Y, Zhou C, Luo S, Lu CS, Pan JY
Cellular & molecular biology letters 2025 Aug 28;30(1):102
Cellular & molecular biology letters 2025 Aug 28;30(1):102
Targeting Irgm1 to combat osteoporosis: suppressing ROS and restoring bone remodeling.
Cui Z, Gu G, Chen F, Li J, Du X, Chen S, Zhang H, Li C, Shao J, Xi J, Du Y, Zhao Q, Xi Y
Cell death & disease 2025 Aug 27;16(1):651
Cell death & disease 2025 Aug 27;16(1):651
KLF11 alleviates rheumatoid arthritis by regulating M1 macrophage polarization via downregulation of YAP1 expression.
Liu X, Fang F, Duan H, Wu C, Liu H, Ding S
Arthritis research & therapy 2025 Aug 26;27(1):171
Arthritis research & therapy 2025 Aug 26;27(1):171
FGF21 Alleviates Hypoxic-Ischemic White Matter Injury in Neonatal Mice by Mediating Inflammation and Oxidative Stress Through PPAR-γ Signaling Pathway.
Fang M, Lu L, Lou J, Ou J, Yu Q, Tao X, Zhu J, Lin Z
Molecular neurobiology 2025 Apr;62(4):4743-4768
Molecular neurobiology 2025 Apr;62(4):4743-4768
Eliminating Radioresistance With a Magnetic Ion-Generator by Simultaneously Augmenting DNA Damage and Diminishing Immunosuppression.
Zhang R, Chen M, Zhou H, Liu Y, Wang Y, Chen C, Li Y, Zeng J, Cui J, Duan R, Gao M
Advanced materials (Deerfield Beach, Fla.) 2025 Apr;37(13):e2406378
Advanced materials (Deerfield Beach, Fla.) 2025 Apr;37(13):e2406378
Implantation of MSC spheroid-derived 3D decellularized ECM enriched with the MSC secretome ameliorates traumatic brain injury and promotes brain repair.
Chen GH, Sia KC, Liu SW, Kao YC, Yang PC, Ho CH, Huang SC, Lee PY, Liang MZ, Chen L, Huang CC
Biomaterials 2025 Apr;315:122941
Biomaterials 2025 Apr;315:122941
An injectable and adaptable system for the sustained release of hydrogen sulfide for targeted diabetic wound therapy by improving the microenvironment of inflammation regulation and angiogenesis.
Zhang H, Dong X, Liu Y, Duan P, Liu C, Liu K, Yu Y, Liang X, Dai H, Yu A
Acta biomaterialia 2025 Apr;196:364-379
Acta biomaterialia 2025 Apr;196:364-379
Dendritic Cell Derived-Extracellular Vesicles Engineered to Express Interleukin-12 and Anti-CTLA-4 on Their Surface for Combinational Cancer Immunotherapy.
Chen J, Tan Q, Yang Z, Chen W, Zhou E, Li M, Deng J, Wu Y, Liu J, Xu J, Guo M, Jin Y
Journal of extracellular vesicles 2025 Apr;14(4):e70068
Journal of extracellular vesicles 2025 Apr;14(4):e70068
S-propargyl-cysteine attenuates temporomandibular joint osteoarthritis by regulating macrophage polarization via Inhibition of JAK/STAT signaling.
Cai W, Wu A, Lin Z, Cao W, Pathak JL, Jaspers RT, Li R, Li X, Zheng K, Lin Y, Zhou N, Zhang X, Zhu Y, Zhang Q
Molecular medicine (Cambridge, Mass.) 2025 Apr 7;31(1):128
Molecular medicine (Cambridge, Mass.) 2025 Apr 7;31(1):128
Platycodon grandiflorum exosome-like nanoparticles: the material basis of fresh platycodon grandiflorum optimality and its mechanism in regulating acute lung injury.
Fu J, Liu Z, Feng Z, Huang J, Shi J, Wang K, Jiang X, Yang J, Ning Y, Lu F, Li L
Journal of nanobiotechnology 2025 Apr 4;23(1):270
Journal of nanobiotechnology 2025 Apr 4;23(1):270
Silybin attenuates microglia-mediated neuroinflammation via inhibition of STING in experimental subarachnoid hemorrhage.
Cui Y, Zhi SM, Ding PF, Zhu T, Chen XX, Liu XZ, Sheng B, Li XJ, Wang J, Zhang JT, Xu MX, Jiang YX, Hang CH, Li W
International immunopharmacology 2025 Apr 4;151:114305
International immunopharmacology 2025 Apr 4;151:114305
A Visible-Light Photocatalysis/Hydrolysis Hydrogen-Generating Nanoplatform for Dynamic Inflammation Management via Immune Metabolism Orchestration during Wound Repair.
Xu Z, Yang Y, Li X, Wang J, Chen S, An T, Hu C, Deng C, Zhou F, Xiang L, Qu Y, Man Y
ACS applied materials & interfaces 2025 Apr 30;17(17):24918-24939
ACS applied materials & interfaces 2025 Apr 30;17(17):24918-24939
Polydopamine-functionalized acellular fish scale scaffolds for accelerated bone tissue regeneration.
Su S, Wang R, Bai J, Gao S, Zhou R, Zhou F
RSC advances 2025 Apr 28;15(18):13857-13873
RSC advances 2025 Apr 28;15(18):13857-13873
Y4 RNA fragment alleviates myocardial injury in heart transplantation via SNRNP200 to enhance IL-10 mRNA splicing.
Lu C, Meng Z, Tang S, Wei H, Hu Y, Chen D, Liu D, Wen H, Dong K, Na N, Huang F, Zeng Z
Molecular therapy : the journal of the American Society of Gene Therapy 2025 Apr 2;33(4):1735-1748
Molecular therapy : the journal of the American Society of Gene Therapy 2025 Apr 2;33(4):1735-1748
Fibroblast derived C3 promotes the progression of experimental periodontitis through macrophage M1 polarization and osteoclast differentiation.
Ren F, Zheng S, Luo H, Yu X, Li X, Song S, Bu W, Sun H
International journal of oral science 2025 Apr 17;17(1):30
International journal of oral science 2025 Apr 17;17(1):30
Parabacteroides distasonis promotes CXCL9 secretion of tumor-associated macrophages and enhances CD8(+)T cell activity to trigger anti-tumor immunity against anti-PD-1 treatment in non-small cell lung cancer mice.
Fan Z, Yi Z, Li S, He J
BMC biotechnology 2025 Apr 16;25(1):30
BMC biotechnology 2025 Apr 16;25(1):30
Probiotic membrane vesicles ameliorate atherosclerotic plaques by promoting lipid efflux and polarization of foamy macrophages.
Jing B, Gao Y, Wang L, Guo F, Jiang D, Qin S, He M, Bai Y, An R, Xie M, Zhang L
Journal of nanobiotechnology 2025 Apr 16;23(1):296
Journal of nanobiotechnology 2025 Apr 16;23(1):296
pH-responsive and self-adaptive injectable sodium alginate/carboxymethyl chitosan hydrogel accelerates infected wound healing by bacteriostasis and immunomodulation.
Zhang X, Liu Y, Wang Z, Zhao H, Zhan L, Gui H, Xu X, Ma X, Ma B
Carbohydrate polymers 2025 Apr 15;354:123322
Carbohydrate polymers 2025 Apr 15;354:123322
Inflammatory Microenvironment-Modulated Conductive Hydrogel Promotes Vascularized Bone Regeneration in Infected Bone Defects.
Yang Q, Wu T, Wu X, Ren M, Liu F, Yang S
ACS biomaterials science & engineering 2025 Apr 14;11(4):2353-2366
ACS biomaterials science & engineering 2025 Apr 14;11(4):2353-2366
Tannic acid‑cerium nanoenzymes serve as broad-spectrum antioxidants to alleviate acute kidney injury by modulating macrophage polarization, mitophagy and endoplasmic reticulum stress.
Fu H, Wang Y, Huang B, Liang Z, Li Y, Cao Z, Wu J, Zhao Y
Journal of controlled release : official journal of the Controlled Release Society 2025 Apr 10;380:892-909
Journal of controlled release : official journal of the Controlled Release Society 2025 Apr 10;380:892-909
Oxalate stimulates macrophage secretion of prostaglandin E2 to promote renal tubular epithelial cell osteogenesis.
Song Q, Chen X, Jiang Q, He Z, Su X, Dong C, Xiang H, Song C, Xiong Y, Yang S
Life sciences 2025 Apr 1;366-367:123476
Life sciences 2025 Apr 1;366-367:123476
Effect of Engineered Cyanobacterial Capsules on a Neurogenic Bladder after Spinal Cord Injury.
Xiao Y, He Y, Zhong D, Liu B, Tang Z, Lan X, Dong Y, Du H, Liu Y, Luo J
ACS nano 2025 Apr 1;19(12):11841-11860
ACS nano 2025 Apr 1;19(12):11841-11860
Bifunctional TRPV1 Targeted Magnetothermal Switch to Attenuate Osteoarthritis Progression.
Lv Z, Wang P, Li W, Xie Y, Sun W, Jin X, Jiang R, Fei Y, Liu Y, Shi T, Guo H, Sun Z, Lin J, Wang X, Tan G, Wu Y, Bao N, Shi D
Research (Washington, D.C.) 2024;7:0316
Research (Washington, D.C.) 2024;7:0316
SNORA5A regulates tumor-associated macrophage M1/M2 phenotypes via TRAF3IP3 in breast cancer.
Zhang Y, Zheng A, Shi Y, Lu H
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2024;57:e13809
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2024;57:e13809
Exosomal SLC16A1-AS1-induced M2 macrophages polarization facilitates hepatocellular carcinoma progression.
Hu Y, Li Y, Xiong H, Zhang Y, Wang F, Zhuo W, Zeng Z, Zhao Y, Wang H, Hu P, Han S, Huang Y, Lv G, Zhao G
International journal of biological sciences 2024;20(11):4341-4363
International journal of biological sciences 2024;20(11):4341-4363
Rhein alleviates MPTP-induced Parkinson's disease by suppressing neuroinflammation via MAPK/IκB pathway.
Qin X, Wang S, Huang J, Hu B, Yang X, Liang L, Zhou R, Huang W
Frontiers in neuroscience 2024;18:1396345
Frontiers in neuroscience 2024;18:1396345
Myeloid Deletion of Cdc42 Protects Liver From Hepatic Ischemia-Reperfusion Injury via Inhibiting Macrophage-Mediated Inflammation in Mice.
He J, Tang MY, Liu LX, Kong CX, Chen W, Wang L, Zhi SB, Sun HW, Huang YC, Chen GY, Xin HB, Deng KY
Cellular and molecular gastroenterology and hepatology 2024;17(6):965-981
Cellular and molecular gastroenterology and hepatology 2024;17(6):965-981
Pretreated MSCs with IronQ Transplantation Attenuate Microglia Neuroinflammation via the cGAS-STING Signaling Pathway.
Yang G, Kantapan J, Mazhar M, Hu Q, Bai X, Zou Y, Wang H, Yang S, Wang L, Dechsupa N
Journal of inflammation research 2024;17:1643-1658
Journal of inflammation research 2024;17:1643-1658
The role of WTAP in regulating macrophage-mediated osteoimmune responses and tissue regeneration in periodontitis.
Li Y, Yang Y, Niu Y, Li Y, Hu Z, Sun S, Chen Y, Hu B, Huang Y, Deng X
Frontiers in immunology 2024;15:1423378
Frontiers in immunology 2024;15:1423378
Assessing immune hepatotoxicity of troglitazone with a versatile liver-immune-microphysiological-system.
Deng Q, Yang Y, Liu Y, Zou M, Huang G, Yang S, Li L, Qu Y, Luo Y, Zhang X
Frontiers in pharmacology 2024;15:1335836
Frontiers in pharmacology 2024;15:1335836
In situ MgO nanoparticle-doped Janus electrospun dressing against bacterial invasion and immune imbalance for irregular wound healing.
Zhou T, Chen Y, Fu L, Wang S, Ding H, Bai Q, Guan J, Mao Y
Regenerative biomaterials 2024;11:rbae107
Regenerative biomaterials 2024;11:rbae107
Enhanced enrichment of extracellular vesicles for laboratory and clinical research from drop-sized blood samples.
Guerrero-Alba A, Bansal S, Sankpal AN, Mitra G, Rahman M, Ravichandran R, Poulson C, Fleming TP, Smith MA, Bremner RM, Mohanakumar T, Sankpal NV
Frontiers in molecular biosciences 2024;11:1365783
Frontiers in molecular biosciences 2024;11:1365783
Microglia aggravate white matter injury via C3/C3aR pathway after experimental subarachnoid hemorrhage.
Yang L, Wu J, Zhang F, Zhang L, Zhang X, Zhou J, Pang J, Xie B, Xie H, Jiang Y, Peng J
Experimental neurology 2024 Sep;379:114853
Experimental neurology 2024 Sep;379:114853
Study on the involvement of microglial S100A8 in neuroinflammation and microglia activation during migraine attacks.
An N, Zhang Y, Xie J, Li J, Lin J, Li Q, Wang Y, Liu Y, Yang Y
Molecular and cellular neurosciences 2024 Sep;130:103957
Molecular and cellular neurosciences 2024 Sep;130:103957
Metabolic Control During Macrophage Polarization by a Citrate-Functionalized Scaffold for Maintaining Bone Homeostasis.
Wu X, Xia Y, Dai H, Hong C, Zhao Y, Wei W, Zheng D
Advanced healthcare materials 2024 Sep;13(22):e2400770
Advanced healthcare materials 2024 Sep;13(22):e2400770
N-acetyltransferase 10 affects the proliferation of intrahepatic cholangiocarcinoma and M2-type polarization of macrophages by regulating C-C motif chemokine ligand 2.
Cai T, Dai J, Lin Y, Bai Z, Li J, Meng W
Journal of translational medicine 2024 Sep 30;22(1):875
Journal of translational medicine 2024 Sep 30;22(1):875
Network Analysis of Gut Microbial Communities Reveals Key Reason for Quercetin Protects against Colitis.
Lv Y, Peng J, Ma X, Liang Z, Salekdeh GH, Ke Q, Shen W, Yan Z, Li H, Wang S, Ding X
Microorganisms 2024 Sep 29;12(10)
Microorganisms 2024 Sep 29;12(10)
GV-971 prevents severe acute pancreatitis by remodeling the microbiota-metabolic-immune axis.
Chen X, Chen X, Yan D, Zhang N, Fu W, Wu M, Ge F, Wang J, Li X, Geng M, Wang J, Tang D, Liu J
Nature communications 2024 Sep 27;15(1):8278
Nature communications 2024 Sep 27;15(1):8278
Macrophage membrane-camouflaged biomimetic nanoparticles for rheumatoid arthritis treatment via modulating macrophage polarization.
Zhou R, Xue S, Cheng Y, Chen Y, Wang Y, Xing J, Liu H, Xu Y, Lin Y, Pei Z, Wei X, Ding J, Li S, Wang K, Yao F, Zhao Y, Ding C, Hu W
Journal of nanobiotechnology 2024 Sep 19;22(1):578
Journal of nanobiotechnology 2024 Sep 19;22(1):578
Involvement of M2 macrophages polarization in PM2.5-induced COPD by upregulating MMP12 via IL4/STAT6 pathway.
Guo X, Yang S, Zhu H, Liu F, Li K, Li G, Lin Y, Yu H, Qiu W, Xu H, Liu Q, Xie X, Sun Y, Zheng P, Chen B, Liu Z, Yuan X, Peng S, Bi X, Yang J, Shao NY, Dai J
Ecotoxicology and environmental safety 2024 Sep 15;283:116793
Ecotoxicology and environmental safety 2024 Sep 15;283:116793
Anti-colorectal cancer activity of mannatide from spent brewer's yeast by regulating immune cells and immune function in the tumor microenvironment.
Li F, Sun X, Gao X, Zhao S, Tavakoli S, Du Z, Wei Y
International journal of biological macromolecules 2024 Sep 11;280(Pt 1):135531
International journal of biological macromolecules 2024 Sep 11;280(Pt 1):135531
CYP24A1 affected macrophage polarization through degradation of vitamin D as a candidate biomarker for ovarian cancer prognosis.
Lin Y, Chen J, Xin S, Lin Y, Chen Y, Zhou X, Chen H, Li X
International immunopharmacology 2024 Sep 10;138:112575
International immunopharmacology 2024 Sep 10;138:112575
Rhein inhibits M1 polarization of BV2 microglia through MAPK/IκB signalling pathway and reduces neurotoxicity caused by neuroinflammation.
Qin X, Li B, Hu B, Huang J, Tian X, Zhang X, Wang Y, Huang W
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 2024 Oct;84(6):533-545
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 2024 Oct;84(6):533-545
PKCα inhibitors promote breast cancer immune evasion by maintaining PD-L1 stability.
Yu J, Xiang Y, Gao Y, Chang S, Kong R, Lv X, Yu J, Jin Y, Li C, Ma Y, Wang Z, Zhou J, Yuan H, Shang S, Hua F, Zhang X, Cui B, Li P
Acta pharmaceutica Sinica. B 2024 Oct;14(10):4378-4395
Acta pharmaceutica Sinica. B 2024 Oct;14(10):4378-4395
Knock-Out of IKKepsilon Ameliorates Atherosclerosis and Fatty Liver Disease by Alterations of Lipid Metabolism in the PCSK9 Model in Mice.
Weiss U, Mungo E, Haß M, Benning D, Gurke R, Hahnefeld L, Dorochow E, Schlaudraff J, Schmid T, Kuntschar S, Meyer S, Medert R, Freichel M, Geisslinger G, Niederberger E
International journal of molecular sciences 2024 Oct 5;25(19)
International journal of molecular sciences 2024 Oct 5;25(19)
Bioactivity-Oriented Separation of "Pepper Alkaloids" from Piper sintenense Hatusima with Potential Antigouty Arthritis Activity.
Yao Z, Li T, Jin M, Fang S, Wang J, Zheng J, Pan K, Zhang J, Zhao G, Yin Z, Huang Y
Journal of agricultural and food chemistry 2024 Oct 30;72(43):23979-23990
Journal of agricultural and food chemistry 2024 Oct 30;72(43):23979-23990
Astragaloside IV augments anti-PD-1 therapy to suppress tumor growth in lung cancer by remodeling the tumor microenvironment.
Wu T, Wu S, Gao H, Liu H, Feng J, Yin G
European journal of histochemistry : EJH 2024 Oct 23;68(4)
European journal of histochemistry : EJH 2024 Oct 23;68(4)
Electroacupuncture attenuates depressive-like behaviors in poststroke depression mice through promoting hippocampal neurogenesis and inhibiting TLR4/NF-κB/NLRP3 signaling pathway.
Li M, Yang F, Zhang X, Yang H, He X, Mao Z, Mao L
Neuroreport 2024 Oct 2;35(14):947-960
Neuroreport 2024 Oct 2;35(14):947-960
Tumor associated antigens combined with carbon dots for inducing durable antitumor immunity.
Liu H, Zhang T, Zheng M, Xie Z
Journal of colloid and interface science 2024 Nov;673:594-606
Journal of colloid and interface science 2024 Nov;673:594-606
The Neuroprotective Mechanisms of PPAR-γ: Inhibition of Microglia-Mediated Neuroinflammation and Oxidative Stress in a Neonatal Mouse Model of Hypoxic-Ischemic White Matter Injury.
Fang M, Yu Q, Ou J, Lou J, Zhu J, Lin Z
CNS neuroscience & therapeutics 2024 Nov;30(11):e70081
CNS neuroscience & therapeutics 2024 Nov;30(11):e70081
Esculetin rebalances M1/M2 macrophage polarization to treat sepsis-induced acute lung injury through regulating metabolic reprogramming.
Chen F, Wang N, Liao J, Jin M, Qu F, Wang C, Lin M, Cui H, Wen W, Chen F
Journal of cellular and molecular medicine 2024 Nov;28(21):e70178
Journal of cellular and molecular medicine 2024 Nov;28(21):e70178
MMP-2-triggered, mitochondria-targeted PROTAC-PDT therapy of breast cancer and brain metastases inhibition.
Tong F, Wang Y, Xu Y, Zhou Y, He S, Du Y, Yang W, Lei T, Song Y, Gong T, Gao H
Nature communications 2024 Nov 29;15(1):10382
Nature communications 2024 Nov 29;15(1):10382
Target-Engineered Liposomes Decorated with Nanozymes Alleviate Liver Fibrosis by Remodeling the Liver Microenvironment.
Yang D, Liu K, Cai C, Xi J, Yan C, Peng Z, Wang Y, Jing L, Zhang Y, Xie F, Li X
ACS applied materials & interfaces 2024 Nov 27;16(47):64536-64553
ACS applied materials & interfaces 2024 Nov 27;16(47):64536-64553
The role of disulfidptosis-associated LncRNA-LINC01137 in Osteosarcoma Biology and its regulatory effects on macrophage polarization.
Tang N, Chen Y, Su Y, Zhang S, Huang T
Functional & integrative genomics 2024 Nov 22;24(6):219
Functional & integrative genomics 2024 Nov 22;24(6):219
Neutrophil extracellular traps promote M1 macrophage polarization in gouty inflammation via targeting hexokinase-2.
Tan H, Zhang S, Zhang Z, Zhang J, Wang Z, Liao J, Qiu X, Jia E
Free radical biology & medicine 2024 Nov 1;224:540-553
Free radical biology & medicine 2024 Nov 1;224:540-553
Versatile dopamine-functionalized hyaluronic acid-recombinant human collagen hydrogel promoting diabetic wound healing via inflammation control and vascularization tissue regeneration.
Wang Y, Zhang Y, Yang YP, Jin MY, Huang S, Zhuang ZM, Zhang T, Cao LL, Lin XY, Chen J, Du YZ, Chen J, Tan WQ
Bioactive materials 2024 May;35:330-345
Bioactive materials 2024 May;35:330-345
Turmeric-Derived Nanoparticles Functionalized Aerogel Regulates Multicellular Networks to Promote Diabetic Wound Healing.
Wu B, Pan W, Luo S, Luo X, Zhao Y, Xiu Q, Zhong M, Wang Z, Liao T, Li N, Liu C, Nie C, Yi G, Lin S, Zou M, Li B, Zheng L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 May;11(18):e2307630
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 May;11(18):e2307630
Inhibition of OGG1 ameliorates pulmonary fibrosis via preventing M2 macrophage polarization and activating PINK1-mediated mitophagy.
Wu W, Jia H, Chen S, Ma X, Zhou S, Qiu L, Wu X, Li P, Chu H, Zhang G
Molecular medicine (Cambridge, Mass.) 2024 May 31;30(1):72
Molecular medicine (Cambridge, Mass.) 2024 May 31;30(1):72
Hypoxia-induced TREM1 promotes mesenchymal-like states of glioma stem cells via alternatively activating tumor-associated macrophages.
Dong M, Zhang X, Peng P, Chen Z, Zhang Y, Wan L, Xiang W, Liu G, Guo Y, Xiao Q, Wang B, Guo D, Zhu M, Yu X, Wan F
Cancer letters 2024 May 28;590:216801
Cancer letters 2024 May 28;590:216801
Podocyte SIRPα reduction aggravates lupus nephritis via promoting T cell inflammatory responses.
Qian B, Lu R, Mao S, Chen Y, Yang M, Zhang W, Zhang M, Zhu D, Liu Z, Zen K, Li L
Cell reports 2024 May 28;43(5):114249
Cell reports 2024 May 28;43(5):114249
Photothermal and Photocatalytic Glycol Chitosan and Polydopamine-Grafted Oxygen Vacancy Bismuth Oxyiodide (BiO(1-x) I) Nanoparticles for the Diagnosis and Targeted Therapy of Diabetic Wounds.
Kong J, Ma S, Chu R, Liu J, Yu H, Mao M, Ge X, Sun Y, Wang Y
Advanced materials (Deerfield Beach, Fla.) 2024 Mar;36(11):e2307695
Advanced materials (Deerfield Beach, Fla.) 2024 Mar;36(11):e2307695
A multifunctional composite nanoparticle with antibacterial activities, anti-inflammatory, and angiogenesis for diabetic wound healing.
Li X, Qu S, Ouyang Q, Qin F, Guo J, Qin M, Zhang J
International journal of biological macromolecules 2024 Mar;260(Pt 2):129531
International journal of biological macromolecules 2024 Mar;260(Pt 2):129531
LncRNA-HOXC-AS2 regulates tumor-associated macrophage polarization through the STAT1/SOCS1 and STAT1/CIITA pathways to promote the progression of non-small cell lung cancer.
Yin C, Li J, Li S, Yang X, Lu Y, Wang C, Liu B
Cellular signalling 2024 Mar;115:111031
Cellular signalling 2024 Mar;115:111031
Restoration of miR-299-3p promotes macrophage phagocytosis and suppresses malignant phenotypes in breast cancer carcinogenesis via dual-targeting CD47 and ABCE1.
Tong S, Zhu Y, Leng Y, Wu Y, Xiao X, Zhao W, Tan S
International immunopharmacology 2024 Mar 30;130:111708
International immunopharmacology 2024 Mar 30;130:111708
Efficient Delivery of Lomitapide using Hybrid Membrane-Coated Tetrahedral DNA Nanostructures for Glioblastoma Therapy.
Song M, Tian J, Wang L, Dong S, Fu K, Chen S, Liu C
Advanced materials (Deerfield Beach, Fla.) 2024 Jun;36(24):e2311760
Advanced materials (Deerfield Beach, Fla.) 2024 Jun;36(24):e2311760
Multifunctional Biodegradable Conductive Hydrogel Regulating Microenvironment for Stem Cell Therapy Enhances the Nerve Tissue Repair.
Xu C, Wu P, Yang K, Mu C, Li B, Li X, Wang Z, Liu Z, Wang X, Luo Z
Small (Weinheim an der Bergstrasse, Germany) 2024 Jun;20(23):e2309793
Small (Weinheim an der Bergstrasse, Germany) 2024 Jun;20(23):e2309793
Gut microbiota mediates the protective effects of β-hydroxybutyrate against cisplatin-induced acute kidney injury.
Tian R, Wang X, Tang S, Zhao L, Hao Y, Li R, Zhou X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jun;175:116752
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jun;175:116752
Prednisone combined with Dihydroartemisinin attenuates systemic lupus erythematosus by regulating M1/M2 balance through the MAPK signaling pathway.
Chen Y, Tao T, Liang Z, Chen X, Xu Y, Zhang T, Zhou D
Molecular immunology 2024 Jun;170:144-155
Molecular immunology 2024 Jun;170:144-155
Exosomes from adipose-derived stem cells regulate macrophage polarization and accelerate diabetic wound healing via the circ-Rps5/miR-124-3p axis.
Yin D, Shen G
Immunity, inflammation and disease 2024 Jun;12(6):e1274
Immunity, inflammation and disease 2024 Jun;12(6):e1274
A Graphene Composite Film Based Wearable Far-Infrared Therapy Apparatus (GRAFT) for Effective Prevention of Postoperative Peritoneal Adhesion.
Lu X, Xu L, Song Y, Yu X, Li Q, Liu F, Li X, Xi J, Wang S, Wang L, Wang Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jun;11(22):e2309330
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jun;11(22):e2309330
Effects of a novel regimen of repetitive transcranial magnetic stimulation (rTMS) on neural remodeling and motor function in adult male mice with ischemic stroke.
Peipei W, Yu D, Xiaoyan L, Yunxia L, Liuming L, Tongbin C, Shaoping L
Journal of neuroscience research 2024 Jun;102(6):e25358
Journal of neuroscience research 2024 Jun;102(6):e25358
The STAT3 inhibitor B9 alleviates lipopolysaccharide-induced acute lung injury through its anti-inflammatory effects.
Cao L, Song H, Zhou S, Lan K, Lv K, Huang M
International immunopharmacology 2024 Jun 30;135:112221
International immunopharmacology 2024 Jun 30;135:112221
Chishao - Fuzi herbal pair restore the macrophage M1/M2 balance in acute-on-chronic liver failure.
Tan N, Jian G, Peng J, Tian X, Chen B
Journal of ethnopharmacology 2024 Jun 28;328:118010
Journal of ethnopharmacology 2024 Jun 28;328:118010
[Aqueous extract of Chuan Xiong Rhizoma enhances inhibitory effect of temozolomide against brain metastasis of melanoma in mice].
Zhao Q, Zhang Z, Zhou X, Rong X, Liu X, Zhao X, Wang H, Pang J, Li S, Li X
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2024 Jun 20;44(6):1088-1097
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2024 Jun 20;44(6):1088-1097
Potential Involvement of M1 Macrophage and VLA4/VCAM-1 Pathway in the Valvular Damage Due to Rheumatic Heart Disease.
Xian S, Li Y, Bai L, Tang S, Meng Z, Wen H, Huang F, Zeng Z
Frontiers in bioscience (Landmark edition) 2024 Jun 18;29(6):219
Frontiers in bioscience (Landmark edition) 2024 Jun 18;29(6):219
Butyrate attenuates sympathetic activation in rats with chronic heart failure by inhibiting microglial inflammation in the paraventricular nucleus.
Liu C, Yu H, Xia H, Wang Z, Li B, Xue H, Jin S, Xiao L, Wu Y, Guo Q
Acta biochimica et biophysica Sinica 2024 Jun 11;56(12):1823-1832
Acta biochimica et biophysica Sinica 2024 Jun 11;56(12):1823-1832
TREM1 facilitates the development of gastric cancer through regulating neutrophil extracellular traps-mediated macrophage polarization.
Yu C, Zhou G, Shi Z, Yu L, Zhou X
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2024 Jul;56(7):1237-1247
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2024 Jul;56(7):1237-1247
Zhen-wu-tang protects against myocardial fibrosis by inhibiting M1 macrophage polarization via the TLR4/NF-κB pathway.
Fang R, Zhou R, Ju D, Li M, Wang H, Pan L, Wang X, Han M, Yu Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul 25;130:155719
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul 25;130:155719
Engineered Mesenchymal Stromal Cell Exosomes-Loaded Microneedles Improve Corneal Healing after Chemical Injury.
Yu F, Zhao X, Wang Q, Fang PH, Liu L, Du X, Li W, He D, Zhang T, Bai Y, Liu L, Li S, Yuan J
ACS nano 2024 Jul 24;
ACS nano 2024 Jul 24;
Virus-Mimetic Extracellular-Vesicle Vaccine Boosts Systemic and Mucosal Immunity via Immune Recruitment.
Li J, Xing H, Meng F, Liu T, Hong X, Han X, Dong Y, Li M, Wang Z, Zhang S, Cui C, Zheng A
ACS nano 2024 Jul 16;
ACS nano 2024 Jul 16;
Microglial FoxO3a deficiency ameliorates ferroptosis-induced brain injury of intracerebral haemorrhage via regulating autophagy and heme oxygenase-1.
Wang R, Liang Z, Xue X, Mei H, Ji L, Wang B, Chen W, Gao C, Yuan S, Wu T, Qi H, Hu S, Yi L, Song Y, Liao R, Chen B
Journal of cellular and molecular medicine 2024 Jan;28(1):e18007
Journal of cellular and molecular medicine 2024 Jan;28(1):e18007
STING modulates iron metabolism to promote liver injury and inflammation in acute immune hepatitis.
Zhao J, Yi Z, Deng G, Li Y, Li J, Qin M, Wu C, Luo P, Ma S, Gao L
Free radical biology & medicine 2024 Jan;210:367-377
Free radical biology & medicine 2024 Jan;210:367-377
Extracellular ATP (eATP) inhibits the progression of endometriosis and enhances the immune function of macrophages.
Zhou L, Cai E, Liu H, Cheng H, Ye X, Zhu H, Chang X
Biochimica et biophysica acta. Molecular basis of disease 2024 Jan;1870(1):166895
Biochimica et biophysica acta. Molecular basis of disease 2024 Jan;1870(1):166895
Regulation of the immune microenvironment by pioglitazone-loaded polylactic glycolic acid nanosphere composite scaffolds to promote vascularization and bone regeneration.
Fan S, Tan Y, Yuan X, Liu C, Wu X, Dai T, Ni S, Wang J, Weng Y, Zhao H
Journal of tissue engineering 2024 Jan-Dec;15:20417314241231452
Journal of tissue engineering 2024 Jan-Dec;15:20417314241231452
Carveol alleviates osteoarthritis progression by acting on synovial macrophage polarization transformation: An in vitro and in vivo study.
Chen S, Xu H, He Y, Meng C, Fan Y, Qu Y, Wang Y, Zhou W, Huang X, You H
Chemico-biological interactions 2024 Jan 5;387:110781
Chemico-biological interactions 2024 Jan 5;387:110781
Discovery of β-sitosterol's effects on molecular changes in rat diabetic wounds and its impact on angiogenesis and macrophages.
Liu Y, Li Z, Li W, Chen X, Yang L, Lu S, Zhou S, Li M, Xiong W, Zhang X, Liu Y, Zhou J
International immunopharmacology 2024 Jan 5;126:111283
International immunopharmacology 2024 Jan 5;126:111283
Mannose-Integrated Nanoparticle Hitchhike Glucose Transporter 1 Recycling to Overcome Various Barriers of Oral Delivery for Alzheimer's Disease Therapy.
Lei T, Yang Z, Jiang C, Wang X, Yang W, Yang X, Xie R, Tong F, Xia X, Huang Q, Du Y, Huang Y, Gao H
ACS nano 2024 Jan 30;18(4):3234-3250
ACS nano 2024 Jan 30;18(4):3234-3250
Mesencephalic astrocyte-derived neurotrophic factor (MANF) alleviates cerebral ischemia/reperfusion injury in mice by regulating microglia polarization via A20/NF-κB pathway.
Zhao X, Wang Z, Wang J, Xu F, Zhang Y, Han D, Fang W
International immunopharmacology 2024 Jan 25;127:111396
International immunopharmacology 2024 Jan 25;127:111396
Epigenetic modification of TWIST1 in macrophages promotes hypertension-induced atherosclerotic plaque instability.
Sun Y, Yao J, Wang C, Jin Y, Wan X, Meng Q, Wu J, Liu Q, Sun H
International immunopharmacology 2024 Jan 25;127:111313
International immunopharmacology 2024 Jan 25;127:111313
Engineered Multifunctional Zinc-Organic Framework-Based Aggregation-Induced Emission Nanozyme for Accelerating Spinal Cord Injury Recovery.
Zheng J, Chen T, Wang K, Peng C, Zhao M, Xie Q, Li B, Lin H, Zhao Z, Ji Z, Tang BZ, Liao Y
ACS nano 2024 Jan 23;18(3):2355-2369
ACS nano 2024 Jan 23;18(3):2355-2369
High glucose impairs cognitive function through inducing mitochondrial calcium overload in Treg cells.
Hui Y, Kuang L, Zhong Y, Tang Y, Xu Z, Zheng T
iScience 2024 Jan 19;27(1):108689
iScience 2024 Jan 19;27(1):108689
Metformin protects ovarian granulosa cells in chemotherapy-induced premature ovarian failure mice through AMPK/PPAR-γ/SIRT1 pathway.
Yang Y, Tang X, Yao T, Zhang Y, Zhong Y, Wu S, Wang Y, Pan Z
Scientific reports 2024 Jan 16;14(1):1447
Scientific reports 2024 Jan 16;14(1):1447
Dictamnine Ameliorates DNFB-Induced Atopic Dermatitis Like Skin Lesions in Mice by Inhibiting M1 Macrophage Polarization and Promoting Autophagy.
Huang Y, Zhao C, Zheng G, Yuan Y, Gong L, Liu R, An J
Biological & pharmaceutical bulletin 2024 Jan 13;47(1):175-186
Biological & pharmaceutical bulletin 2024 Jan 13;47(1):175-186
C-C Motif Chemokine 2 Regulates Macrophage Polarization and Contributes to Myocardial Infarction Healing.
Chen L, Pan D, Zhang Y, Zhang E, Ma L
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2024 Feb;44(2):68-79
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2024 Feb;44(2):68-79
Macrophage Activation in Synovitis and Osteoarthritis of Temporomandibular Joint and Its Relationship with the Progression of Synovitis and Bone Remodeling.
Hu S, Li H, Jiang H, Liu X, Ke J, Long X
The American journal of pathology 2024 Feb;194(2):296-306
The American journal of pathology 2024 Feb;194(2):296-306
Transplantation of fibrin-thrombin encapsulated human induced neural stem cells promotes functional recovery of spinal cord injury rats through modulation of the microenvironment.
Liu S, Liu B, Li Q, Zheng T, Liu B, Li M, Chen Z
Neural regeneration research 2024 Feb;19(2):440-446
Neural regeneration research 2024 Feb;19(2):440-446
Gut microbiome-based thiamine metabolism contributes to the protective effect of one acidic polysaccharide from Selaginella uncinata (Desv.) Spring against inflammatory bowel disease.
Hui H, Wang Z, Zhao X, Xu L, Yin L, Wang F, Qu L, Peng J
Journal of pharmaceutical analysis 2024 Feb;14(2):177-195
Journal of pharmaceutical analysis 2024 Feb;14(2):177-195
Biomimetic Corneal Stroma for Scarless Corneal Wound Healing via Structural Restoration and Microenvironment Modulation.
Huang J, Jiang T, Li J, Qie J, Cheng X, Wang Y, Zhou T, Liu J, Han H, Yao K, Yu L
Advanced healthcare materials 2024 Feb;13(5):e2302889
Advanced healthcare materials 2024 Feb;13(5):e2302889
Three Birds, One Stone: An Osteo-Microenvironment Stage-Regulative Scaffold for Bone Defect Repair through Modulating Early Osteo-Immunomodulation, Middle Neovascularization, and Later Osteogenesis.
Yuan Y, Xu Y, Mao Y, Liu H, Ou M, Lin Z, Zhao R, Long H, Cheng L, Sun B, Zhao S, Zeng M, Lu B, Lu H, Zhu Y, Chen C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Feb;11(6):e2306428
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Feb;11(6):e2306428
Mitochondrial-related genes PDK2, CHDH, and ALDH5A1 served as a diagnostic signature and correlated with immune cell infiltration in ulcerative colitis.
Yang Q, Zhang P, Han L, Shi P, Zhao Z, Cui D, Hong K
Aging 2024 Feb 19;16(4):3803-3822
Aging 2024 Feb 19;16(4):3803-3822
Chronic exposure to polystyrene microplastics induces renal fibrosis via ferroptosis.
Hong R, Shi Y, Fan Z, Gao Y, Chen H, Pan C
Toxicology 2024 Dec;509:153996
Toxicology 2024 Dec;509:153996
Targeted reprogramming of tumor-associated macrophages for overcoming glioblastoma resistance to chemotherapy and immunotherapy.
Li J, Yang J, Jiang S, Tian Y, Zhang Y, Xu L, Hu B, Shi H, Li Z, Ran G, Huang Y, Ruan S
Biomaterials 2024 Dec;311:122708
Biomaterials 2024 Dec;311:122708
MSCs-derived ECM functionalized hydrogel regulates macrophage reprogramming for osteoarthritis treatment by improving mitochondrial function and energy metabolism.
Chen Z, Pang Q, Zhan J, Liu J, Zhao W, Dong L, Huang W
Materials today. Bio 2024 Dec;29:101340
Materials today. Bio 2024 Dec;29:101340
Licochalcone A loaded multifunctional chitosan hyaluronic acid hydrogel with antibacterial and inflammatory regulating effects to promote wound healing.
Hou Z, Wang Y, Chen S, Luo Z, Liu Y
International journal of biological macromolecules 2024 Dec;283(Pt 1):137458
International journal of biological macromolecules 2024 Dec;283(Pt 1):137458
Preparation of recombinant type I collagen (PF-I-80) and its functional characterization and biomedical applications in wound healing.
Zhang Y, Fu R, Zhu C, Yuwen W, Zhang J, Duan Z, Fan D
International journal of biological macromolecules 2024 Dec;282(Pt 1):136679
International journal of biological macromolecules 2024 Dec;282(Pt 1):136679
Indole-3-Carboxaldehyde Inhibits Inflammatory Response and Lipid Accumulation in Macrophages Through the miR-1271-5p/HDAC9 Pathway.
Luo W, Meng J, Yu XH, Zhang ZZ, Wang G, He J
Journal of cellular and molecular medicine 2024 Dec;28(24):e70263
Journal of cellular and molecular medicine 2024 Dec;28(24):e70263
Controlled Release of Ceria and Ferric Oxide Nanoparticles via Collagen Hydrogel for Enhanced Osteoarthritis Therapy.
Chen X, Wang L, Zhang J, Yan H, Wang S, Xiao J
Advanced healthcare materials 2024 Dec;13(32):e2401507
Advanced healthcare materials 2024 Dec;13(32):e2401507
Hierarchical Integration of Curcumin-Loaded CaCO(3) Nanoparticles and Black Phosphorus Nanosheets in Core/Shell Nanofiber for Cranial Defect Repair.
Zheng Y, Tan L, Chen H, He S, Li M, Luo Z, Cai K, Hu Y
Advanced healthcare materials 2024 Dec;13(30):e2401786
Advanced healthcare materials 2024 Dec;13(30):e2401786
Kongensin A targeting PI3K attenuates inflammation-induced osteoarthritis by modulating macrophage polarization and alleviating inflammatory signaling.
Guo Y, Wang P, Hu B, Wang L, Zhang Y, Wang J
International immunopharmacology 2024 Dec 5;142(Pt A):112948
International immunopharmacology 2024 Dec 5;142(Pt A):112948
Long-term hypothermia amplified neuroprotection by antagonizing intracranial pressure rebound after severe traumatic brain injury in rats.
Sun X, Xu S, Wang J, Li X, Sun H, Zhao W
Neuroreport 2024 Dec 4;35(17):1107-1116
Neuroreport 2024 Dec 4;35(17):1107-1116
Exosomes derived from minor salivary gland mesenchymal stem cells: a promising novel exosome exhibiting pro-angiogenic and wound healing effects similar to those of adipose-derived stem cell exosomes.
Xiang H, Ding P, Qian J, Lu E, Sun Y, Lee S, Zhao Z, Sun Z, Zhao Z
Stem cell research & therapy 2024 Dec 3;15(1):462
Stem cell research & therapy 2024 Dec 3;15(1):462
Identifying specific functional roles for senescence across cell types.
Zhao H, Liu Z, Chen H, Han M, Zhang M, Liu K, Jin H, Liu X, Shi M, Pu W, Werner M, Meister M, Kauschke SG, Sun R, Wang J, Shen R, Wang QD, Ma X, Tchorz JS, Zhou B
Cell 2024 Dec 12;187(25):7314-7334.e21
Cell 2024 Dec 12;187(25):7314-7334.e21
Polydopamine-coated bioactive glass for immunomodulation and odontogenesis in pulpitis.
Li J, Wu J, Zhu L, Mao S, Wang S, Jia P, Dong Y
Materials today. Bio 2024 Aug;27:101130
Materials today. Bio 2024 Aug;27:101130
Dissection of triple-negative breast cancer microenvironment and identification of potential therapeutic drugs using single-cell RNA sequencing analysis.
Cheng W, Mi W, Wang S, Wang X, Jiang H, Chen J, Yang K, Jiang W, Ye J, Guo B, Zhang Y
Journal of pharmaceutical analysis 2024 Aug;14(8):100975
Journal of pharmaceutical analysis 2024 Aug;14(8):100975
rTMS applied to the PFC relieves neuropathic pain and modulates neuroinflammation in CCI rats.
Yang Y, Xia C, Xu Z, Hu Y, Huang M, Li D, Zheng Y, Li Y, Xu F, Wang J
Neuroscience 2024 Aug 30;554:137-145
Neuroscience 2024 Aug 30;554:137-145
Neural epidermal growth factor-like 1 protein (Nell-1) alleviates periodontal tissue destruction in periodontitis by regulating the ratio of M2/M1 macrophage phenotypes.
Ni C, Liao W, Nie H, Ge R, Liu R, Zou X, Yuan Z, Yan F
International immunopharmacology 2024 Aug 20;137:112522
International immunopharmacology 2024 Aug 20;137:112522
Inhibiting PRMT1 protects against CoNV by regulating macrophages through the FGF2/PI3K/Akt pathway.
Gao Y, Mao J, Zhang R, Deng Q, Wang Y, Pan Y, Liudi S, Wang Y, Fan X, Yang Y, Wan S
European journal of pharmacology 2024 Aug 15;977:176673
European journal of pharmacology 2024 Aug 15;977:176673
Fisetin Promotes Functional Recovery after Spinal Cord Injury by Inhibiting Microglia/Macrophage M1 Polarization and JAK2/STAT3 Signaling Pathway.
Ji R, Hao Z, Wang H, Su Y, Yang W, Li X, Duan L, Guan F, Ma S
Journal of agricultural and food chemistry 2024 Aug 14;72(32):17964-17976
Journal of agricultural and food chemistry 2024 Aug 14;72(32):17964-17976
IRF4 induces M1 macrophage polarization and aggravates ulcerative colitis progression by the Bcl6-dependent STAT3 pathway.
Wang J, Wu Z, Huang Y, Jin L, Xu J, Yao Z, Ouyang X, Zhou Z, Mao S, Cao J, Lai B, Shen W
Environmental toxicology 2024 Apr;39(4):2390-2404
Environmental toxicology 2024 Apr;39(4):2390-2404
A systematic strategy for investigating the pharmacological effects and mechanism of traditional Chinese medicinal formula: Guilin Xiguashuang as a case.
Zhang J, Ren Y, Liu Y, Wang Z, Li Y, Li C, Chang H, Zhang Y
Fundamental & clinical pharmacology 2024 Apr;38(2):238-251
Fundamental & clinical pharmacology 2024 Apr;38(2):238-251
Enriched environment treatment promotes neural functional recovery together with microglia polarization and remyelination after cerebral ischemia in rats.
Han Y, Shen X, Gao Z, Han P, Bi X
Brain research bulletin 2024 Apr;209:110912
Brain research bulletin 2024 Apr;209:110912
Ferrous/Ferric Ions Crosslinked Type II Collagen Multifunctional Hydrogel for Advanced Osteoarthritis Treatment.
Wang L, Chen X, Wang S, Ma J, Yang X, Chen H, Xiao J
Advanced healthcare materials 2024 Apr;13(10):e2302833
Advanced healthcare materials 2024 Apr;13(10):e2302833
Dehydroandrographolide facilitates M2 macrophage polarization by downregulating DUSP3 to inhibit sepsis-associated acute kidney injury.
Shao Y, Yu W, Cai H
Immunity, inflammation and disease 2024 Apr;12(4):e1249
Immunity, inflammation and disease 2024 Apr;12(4):e1249
Myricetin Oligomer Triggers Multi-Receptor Mediated Penetration and Autophagic Restoration of Blood-Brain Barrier for Ischemic Stroke Treatment.
Liu L, Ma Z, Han Q, Meng W, Wang H, Guan X, Shi Q
ACS nano 2024 Apr 9;18(14):9895-9916
ACS nano 2024 Apr 9;18(14):9895-9916
FDA compound library screening Baicalin upregulates TREM2 for the treatment of cerebral ischemia-reperfusion injury.
Wang H, Ma J, Li X, Peng Y, Wang M
European journal of pharmacology 2024 Apr 15;969:176427
European journal of pharmacology 2024 Apr 15;969:176427
Transcriptome sequencing reveals novel biomarkers and immune cell infiltration in esophageal tumorigenesis.
Sun JR, Chen DM, Huang R, Wang RT, Jia LQ
World journal of gastrointestinal oncology 2024 Apr 15;16(4):1500-1513
World journal of gastrointestinal oncology 2024 Apr 15;16(4):1500-1513
Pathological BBB Crossing Melanin-Like Nanoparticles as Metal-Ion Chelators and Neuroinflammation Regulators against Alzheimer's Disease.
Huang Q, Jiang C, Xia X, Wang Y, Yan C, Wang X, Lei T, Yang X, Yang W, Cheng G, Gao H
Research (Washington, D.C.) 2023;6:0180
Research (Washington, D.C.) 2023;6:0180
CD86 Is Associated with Immune Infiltration and Immunotherapy Signatures in AML and Promotes Its Progression.
Zhang Q, Ma R, Chen H, Guo W, Li Z, Xu K, Chen W
Journal of oncology 2023;2023:9988405
Journal of oncology 2023;2023:9988405
Periventricular Microglia Polarization and Morphological Changes Accompany NLRP3 Inflammasome-Mediated Neuroinflammation after Hypoxic-Ischemic White Matter Damage in Premature Rats.
Yang L, Zhang Y, Yu X, Li D, Liu N, Xue X, Fu J
Journal of immunology research 2023;2023:5149306
Journal of immunology research 2023;2023:5149306
Identifying Macrophage-Related Genes in Ulcerative Colitis Using Weighted Coexpression Network Analysis and Machine Learning.
Hong S, Wang H, Chan S, Zhang J, Chen B, Ma X, Chen X
Mediators of inflammation 2023;2023:4373840
Mediators of inflammation 2023;2023:4373840
Based on disulfidptosis-related glycolytic genes to construct a signature for predicting prognosis and immune infiltration analysis of hepatocellular carcinoma.
Wang Z, Chen X, Zhang J, Chen X, Peng J, Huang W
Frontiers in immunology 2023;14:1204338
Frontiers in immunology 2023;14:1204338
Engineered exosomes derived from miR-132-overexpresssing adipose stem cells promoted diabetic wound healing and skin reconstruction.
Ge L, Wang K, Lin H, Tao E, Xia W, Wang F, Mao C, Feng Y
Frontiers in bioengineering and biotechnology 2023;11:1129538
Frontiers in bioengineering and biotechnology 2023;11:1129538
Macrophage-Derived Cathepsin S Remodels the Extracellular Matrix to Promote Liver Fibrogenesis.
Zuo T, Xie Q, Liu J, Yang J, Shi J, Kong D, Wang Y, Zhang Z, Gao H, Zeng DB, Wang X, Tao P, Wei W, Wang J, Li Y, Long Q, Li C, Chang L, Ning H, Li Y, Cui C, Ge X, Wu J, Li G, Hong X, Yang X, Dai E, He F, Wu J, Ruan Y, Lu S, Xu P
Gastroenterology 2023 Sep;165(3):746-761.e16
Gastroenterology 2023 Sep;165(3):746-761.e16
Early depletion of M1 macrophages retards the progression of glucocorticoid-associated osteonecrosis of the femoral head.
Cheng Y, Chen H, Duan P, Zhang H, Yu Y, Yu J, Yu Z, Zheng L, Ye X, Pan Z
International immunopharmacology 2023 Sep;122:110639
International immunopharmacology 2023 Sep;122:110639
Ursolic Acid Alleviates Neuroinflammation after Intracerebral Hemorrhage by Mediating Microglial Pyroptosis via the NF-κB/NLRP3/GSDMD Pathway.
Lei P, Li Z, Hua Q, Song P, Gao L, Zhou L, Cai Q
International journal of molecular sciences 2023 Sep 30;24(19)
International journal of molecular sciences 2023 Sep 30;24(19)
The crosstalk between M1 macrophage polarization and energy metabolism disorder contributes to polystyrene nanoplastics-triggered testicular inflammation.
Li S, Liu L, Luo G, Yuan Y, Hu D, Xiao F
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Oct;180:114002
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Oct;180:114002
In vitro acne disease model from inertial focusing effect for studying the interactions between sebocyte glands and macrophages.
Tang T, Xu Y, Wang L, Zhang P
Biotechnology journal 2023 Nov;18(11):e2300108
Biotechnology journal 2023 Nov;18(11):e2300108
Knockdown of repulsive guidance molecule a promotes polarization of microglia into an anti-inflammatory phenotype after oxygen-glucose deprivation-reoxygenation in vitro.
Shen G, Xiao H, Huang S, Yuan X, Rongrong Z, Ma Y, Qin X
Neurochemistry international 2023 Nov;170:105546
Neurochemistry international 2023 Nov;170:105546
CTRP6 regulates M1 macrophage polarization via the PPAR-γ/NF-κB pathway and reprogramming glycolysis in recurrent spontaneous abortion.
Yan S, Ding J, Wang Z, Zhang F, Li J, Zhang Y, Wu S, Yang L, Pang X, Zhang Y, Yang J
International immunopharmacology 2023 Nov;124(Pt A):110840
International immunopharmacology 2023 Nov;124(Pt A):110840
Silk Acid as an Implantable Biomaterial for Tissue Regeneration.
Sun Z, Huang R, Lyu H, Yu X, Wang W, Li J, Lu X, Guo C
Advanced healthcare materials 2023 Nov;12(28):e2301439
Advanced healthcare materials 2023 Nov;12(28):e2301439
Irf7 regulates the expression of Srg3 and ferroptosis axis aggravated sepsis-induced acute lung injury.
Ling X, Wei S, Ling D, Cao S, Chang R, Wang Q, Yuan Z
Cellular & molecular biology letters 2023 Nov 9;28(1):91
Cellular & molecular biology letters 2023 Nov 9;28(1):91
Role of low-intensity pulsed ultrasound in regulating macrophage polarization to accelerate tendon-bone interface repair.
Xu Z, Li S, Wan L, Hu J, Lu H, Zhang T
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2023 May;41(5):919-929
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2023 May;41(5):919-929
Spontaneous immunomodulation and regulation of angiogenesis and osteogenesis by Sr/Cu-borosilicate glass (BSG) bone cement to repair critical bone defects.
Li S, Zhang L, Liu C, Kim J, Su K, Chen T, Zhao L, Lu X, Zhang H, Cui Y, Cui X, Yuan F, Pan H
Bioactive materials 2023 May;23:101-117
Bioactive materials 2023 May;23:101-117
Bioengineered stem cell membrane functionalized nanoparticles combine anti-inflammatory and antimicrobial properties for sepsis treatment.
Lu L, Quan L, Li J, Yuan J, Nie X, Huang X, Dong H, Su Y, Huang Y, Kou Q, Liu L, Liu H, Zhou X, Gui R, Gu L
Journal of nanobiotechnology 2023 May 26;21(1):170
Journal of nanobiotechnology 2023 May 26;21(1):170
Dual role of ANGPTL8 in promoting tumor cell proliferation and immune escape during hepatocarcinogenesis.
Gao Y, Yuan Y, Wen S, Chen Y, Zhang Z, Feng Y, Jiang B, Ma S, Hu R, Fang C, Ruan X, Yuan Y, Fang X, Luo C, Meng Z, Wang X, Guo X
Oncogenesis 2023 May 15;12(1):26
Oncogenesis 2023 May 15;12(1):26
Exploring the effect of Er miao San-containing serum on macrophage polarization through miR-33/NLRP3 pathway.
Liu M, Wang J, Chen S, Meng X, Cheng Z, Wang J, Tan Y, Su W, Lu Z, Zhang M, Jia X
Journal of ethnopharmacology 2023 May 10;307:116178
Journal of ethnopharmacology 2023 May 10;307:116178
Apigenin Alleviates Autoimmune Uveitis by Inhibiting Microglia M1 Pro-Inflammatory Polarization.
Shu N, Zhang Z, Wang X, Li R, Li W, Liu X, Zhang Q, Jiang Z, Tao L, Zhang L, Hou S
Investigative ophthalmology & visual science 2023 May 1;64(5):21
Investigative ophthalmology & visual science 2023 May 1;64(5):21
Role of nuclear factor of activated T Cells-1 in Sepsis-induced behavioral deficits in mice.
Jiang F, Guo Y, Hu L, Zhang M, Meng J, Si Y, Shi H
Brain research 2023 May 1;1806:148299
Brain research 2023 May 1;1806:148299
Large extracellular vesicles secreted by human iPSC-derived MSCs ameliorate tendinopathy via regulating macrophage heterogeneity.
Ye T, Chen Z, Zhang J, Luo L, Gao R, Gong L, Du Y, Xie Z, Zhao B, Li Q, Wang Y
Bioactive materials 2023 Mar;21:194-208
Bioactive materials 2023 Mar;21:194-208
Cadmium contributes to atherosclerosis by affecting macrophage polarization.
Wan Y, Mo L, Huang H, Mo L, Zhu W, Li W, Yang G, Chen L, Wu Y, Song J, Yang X
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Mar;173:113603
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Mar;173:113603
Synthesis of oxidized sodium alginate and its electrospun bio-hybrids with zinc oxide nanoparticles to promote wound healing.
Wang W, Liu M, Shafiq M, Li H, Hashim R, El-Newehy M, El-Hamshary H, Morsi Y, Mo X
International journal of biological macromolecules 2023 Mar 31;232:123480
International journal of biological macromolecules 2023 Mar 31;232:123480
Metformin Attenuates the Inflammatory Response via the Regulation of Synovial M1 Macrophage in Osteoarthritis.
Zheng M, Zhu Y, Wei K, Pu H, Peng R, Xiao J, Liu C, Sun X
International journal of molecular sciences 2023 Mar 10;24(6)
International journal of molecular sciences 2023 Mar 10;24(6)
Extracellular vesicle-derived LINC00511 promotes glycolysis and mitochondrial oxidative phosphorylation of pancreatic cancer through macrophage polarization by microRNA-193a-3p-dependent regulation of plasminogen activator urokinase.
Zhang T, Yu H, Bai Y, Song J, Chen J, Li Y, Cui Y
Immunopharmacology and immunotoxicology 2023 Jun;45(3):355-369
Immunopharmacology and immunotoxicology 2023 Jun;45(3):355-369
Intracellular hydrogelation of macrophage conjugated probiotics for hitchhiking delivery and combined treatment of colitis.
Wang J, Hu D, Chen Q, Liu T, Zhou X, Xu Y, Zhou H, Gu D, Gao C
Materials today. Bio 2023 Jun;20:100679
Materials today. Bio 2023 Jun;20:100679
Erythrocyte membrane-camouflaged DNA-functionalized upconversion nanoparticles for tumor-targeted chemotherapy and immunotherapy.
Kou Q, Huang Y, Su Y, Lu L, Li X, Jiang H, Huang R, Li J, Nie X
Nanoscale 2023 Jun 1;15(21):9457-9476
Nanoscale 2023 Jun 1;15(21):9457-9476
Photo-Responsive Hydrogel for Contactless Dressing Change to Attenuate Secondary Damage and Promote Diabetic Wound Healing.
Li ZY, Zhang XJ, Gao YM, Song Y, Sands MX, Zhou SB, Li QF, Zhang J
Advanced healthcare materials 2023 Jul;12(17):e2202770
Advanced healthcare materials 2023 Jul;12(17):e2202770
SGLT2 inhibitor dapagliflozin alleviates intramyocardial hemorrhage and adverse ventricular remodeling via suppressing hepcidin in myocardial ischemia-reperfusion injury.
Chen R, Zhang Y, Zhang H, Zhou H, Tong W, Wu Y, Ma M, Chen Y
European journal of pharmacology 2023 Jul 5;950:175729
European journal of pharmacology 2023 Jul 5;950:175729
MCP-1-Loaded Poly(l-lactide-co-caprolactone) Fibrous Films Modulate Macrophage Polarization toward an Anti-inflammatory Phenotype and Improve Angiogenesis.
Cheng C, Li H, Liu J, Wu L, Fang Z, Xu G
ACS biomaterials science & engineering 2023 Jul 10;9(7):4356-4367
ACS biomaterials science & engineering 2023 Jul 10;9(7):4356-4367
Nonenzymatic function of DPP4 promotes diabetes-associated cognitive dysfunction through IGF-2R/PKA/SP1/ERp29/IP3R2 pathway-mediated impairment of Treg function and M1 microglia polarization.
Hui Y, Xu Z, Li J, Kuang L, Zhong Y, Tang Y, Wei J, Zhou H, Zheng T
Metabolism: clinical and experimental 2023 Jan;138:155340
Metabolism: clinical and experimental 2023 Jan;138:155340
Exploration of the mechanism by which Huangqi Guizhi Wuwu decoction inhibits Lps-induced inflammation by regulating macrophage polarization based on network pharmacology.
Wang S, Ji T, Wang L, Qu Y, Wang X, Wang W, Lv M, Wang Y, Li X, Jiang P
BMC complementary medicine and therapies 2023 Jan 9;23(1):8
BMC complementary medicine and therapies 2023 Jan 9;23(1):8
Chronic Microcystin-LR-Induced α-Synuclein Promotes Neuroinflammation Through Activation of the NLRP3 Inflammasome in Microglia.
Yan M, Jin H, Pan C, Han X
Molecular neurobiology 2023 Feb;60(2):884-900
Molecular neurobiology 2023 Feb;60(2):884-900
Castor1 overexpression regulates microglia M1/M2 polarization via inhibiting mTOR pathway.
Hu H, Lu X, Huang L, He Y, Liu X, Wang Y, Duan C
Metabolic brain disease 2023 Feb;38(2):699-708
Metabolic brain disease 2023 Feb;38(2):699-708
Converting bacteria into autologous tumor vaccine via surface biomineralization of calcium carbonate for enhanced immunotherapy.
Guo L, Ding J, Zhou W
Acta pharmaceutica Sinica. B 2023 Dec;13(12):5074-5090
Acta pharmaceutica Sinica. B 2023 Dec;13(12):5074-5090
SUV39H1 is a prognosis and immune microenvironment-related biomarker in diffuse large B-cell lymphoma.
Zhang Y, Qian S, Wen Q, Lei Y, Ge J, Kong X, Wang W, Wang Z, Hou H, Tang C, Wu S, Wang G, Li W, Zhang M, Zhang X, Chen Q
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2023 Aug;25(8):2438-2450
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2023 Aug;25(8):2438-2450
Hollow copper sulfide nanoparticles carrying ISRIB for the sensitized photothermal therapy of breast cancer and brain metastases through inhibiting stress granule formation and reprogramming tumor-associated macrophages.
Tong F, Hu H, Xu Y, Zhou Y, Xie R, Lei T, Du Y, Yang W, He S, Huang Y, Gong T, Gao H
Acta pharmaceutica Sinica. B 2023 Aug;13(8):3471-3488
Acta pharmaceutica Sinica. B 2023 Aug;13(8):3471-3488
Constitutive aryl hydrocarbon receptor facilitates the regenerative potential of mouse bone marrow mesenchymal stromal cells.
Huang J, Wang YN, Zhou Y
World journal of stem cells 2023 Aug 26;15(8):807-820
World journal of stem cells 2023 Aug 26;15(8):807-820
Melatonin ameliorates neurological deficits through MT2/IL-33/ferritin H signaling-mediated inhibition of neuroinflammation and ferroptosis after traumatic brain injury.
Gao Y, Wang T, Cheng Y, Wu Y, Zhu L, Gu Z, Wu Y, Cai L, Wu Y, Zhang Y, Gao C, Li L, Li J, Li Q, Wang Z, Wang Y, Wang F, Luo C, Tao L
Free radical biology & medicine 2023 Apr;199:97-112
Free radical biology & medicine 2023 Apr;199:97-112
Reversal of Pulmonary Fibrosis: Human Umbilical Mesenchymal Stem Cells from Wharton's Jelly versus Human-Adipose-Derived Mesenchymal Stem Cells.
Chu KA, Yeh CC, Hsu CH, Hsu CW, Kuo FH, Tsai PJ, Fu YS
International journal of molecular sciences 2023 Apr 8;24(8)
International journal of molecular sciences 2023 Apr 8;24(8)
Identification of the Prognostic Biomarkers CBX6 and CBX7 in Bladder Cancer.
Li X, Li L, Xiong X, Kuang Q, Peng M, Zhu K, Luo P
Diagnostics (Basel, Switzerland) 2023 Apr 11;13(8)
Diagnostics (Basel, Switzerland) 2023 Apr 11;13(8)
Regulatory Effects of Three-Dimensional Cultured Lipopolysaccharide-Pretreated Periodontal Ligament Stem Cell-Derived Secretome on Macrophages.
Su Y, Ai S, Shen Y, Cheng W, Xu C, Sui L, Zhao Y
International journal of molecular sciences 2023 Apr 10;24(8)
International journal of molecular sciences 2023 Apr 10;24(8)
Antiliver Fibrosis Formula of Fuzheng Huayu Alleviates Inflammatory Response.
Chang QQ, Pan YF, Yang JY, Li RS, Yuan CL, Liao YF, Zhang DD, Liu CH
Evidence-based complementary and alternative medicine : eCAM 2022;2022:5752803
Evidence-based complementary and alternative medicine : eCAM 2022;2022:5752803
Cayratia japonica Prevents Ulcerative Colitis by Promoting M2 Macrophage Polarization through Blocking the TLR4/MAPK/NF-κB Pathway.
Sun J, Zhao P, Ding X, Li F, Jiang J, Huang H, Ji L
Mediators of inflammation 2022;2022:1108569
Mediators of inflammation 2022;2022:1108569
NCOA4-Mediated Ferroptosis in Bronchial Epithelial Cells Promotes Macrophage M2 Polarization in COPD Emphysema.
Liu J, Zhang Z, Yang Y, Di T, Wu Y, Bian T
International journal of chronic obstructive pulmonary disease 2022;17:667-681
International journal of chronic obstructive pulmonary disease 2022;17:667-681
Self-Assembly Catalase Nanocomplex Conveyed by Bacterial Vesicles for Oxygenated Photodynamic Therapy and Tumor Immunotherapy.
Zhang J, Li Z, Liu L, Li L, Zhang L, Wang Y, Zhao J
International journal of nanomedicine 2022;17:1971-1985
International journal of nanomedicine 2022;17:1971-1985
Novel recombinant protein flagellin A N/C attenuates experimental autoimmune encephalomyelitis by suppressing the ROS/NF-κB/NLRP3 signaling pathway.
Li L, Deng S, Liu M, Yang M, Li J, Liu T, Zhang T, Zhao Y, He M, Wu D, Xu Y
Frontiers in pharmacology 2022;13:956402
Frontiers in pharmacology 2022;13:956402
Qing-Wen-Jie-Re Mixture Ameliorates Poly (I:C)-Induced Viral Pneumonia Through Regulating the Inflammatory Response and Serum Metabolism.
Li Q, Zhang T, Wang Y, Yang S, Luo J, Fang F, Liao J, Wen W, Cui H, Shang H
Frontiers in pharmacology 2022;13:891851
Frontiers in pharmacology 2022;13:891851
TGFBI secreted by tumor-associated macrophages promotes glioblastoma stem cell-driven tumor growth via integrin αvβ5-Src-Stat3 signaling.
Peng P, Zhu H, Liu D, Chen Z, Zhang X, Guo Z, Dong M, Wan L, Zhang P, Liu G, Zhang S, Dong F, Hu F, Cheng F, Huang S, Guo D, Zhang B, Yu X, Wan F
Theranostics 2022;12(9):4221-4236
Theranostics 2022;12(9):4221-4236
Non-invasive photobiomodulation treatment in an Alzheimer Disease-like transgenic rat model.
Yang L, Wu C, Parker E, Li Y, Dong Y, Tucker L, Brann DW, Lin HW, Zhang Q
Theranostics 2022;12(5):2205-2231
Theranostics 2022;12(5):2205-2231
Protective effects of (R)-enantiomers but not (S)-enantiomers of β2-adrenergic receptor agonists against acute colitis: The role of β2AR.
Deng L, Wang S, Zhang R, Huang J, Lin Y, Liu X, Lu Z, Li M, Tan W
International immunopharmacology 2022 Sep;110:108997
International immunopharmacology 2022 Sep;110:108997
A Combination Therapy Using Electrical Stimulation and Adaptive, Conductive Hydrogels Loaded with Self-Assembled Nanogels Incorporating Short Interfering RNA Promotes the Repair of Diabetic Chronic Wounds.
Lei H, Fan D
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Oct;9(30):e2201425
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Oct;9(30):e2201425
Engineered Bacterial Outer Membrane Vesicles as Controllable Two-Way Adaptors to Activate Macrophage Phagocytosis for Improved Tumor Immunotherapy.
Feng Q, Ma X, Cheng K, Liu G, Li Y, Yue Y, Liang J, Zhang L, Zhang T, Wang X, Gao X, Nie G, Zhao X
Advanced materials (Deerfield Beach, Fla.) 2022 Oct;34(40):e2206200
Advanced materials (Deerfield Beach, Fla.) 2022 Oct;34(40):e2206200
A ROS-Responsive Liposomal Composite Hydrogel Integrating Improved Mitochondrial Function and Pro-Angiogenesis for Efficient Treatment of Myocardial Infarction.
Zheng Z, Lei C, Liu H, Jiang M, Zhou Z, Zhao Y, Yu CY, Wei H
Advanced healthcare materials 2022 Oct;11(19):e2200990
Advanced healthcare materials 2022 Oct;11(19):e2200990
Ultrasound-augmented anti-inflammatory exosomes for targeted therapy in rheumatoid arthritis.
Tang Y, Wu Z, Guo R, Huang J, Rong X, Zhu B, Wang L, Ma L, Cheng C, Qiu L
Journal of materials chemistry. B 2022 Oct 5;10(38):7862-7874
Journal of materials chemistry. B 2022 Oct 5;10(38):7862-7874
Application of Bone Marrow-Derived Macrophages Combined with Bone Mesenchymal Stem Cells in Dual-Channel Three-Dimensional Bioprinting Scaffolds for Early Immune Regulation and Osteogenic Induction in Rat Calvarial Defects.
Yu K, Huangfu H, Qin Q, Zhang Y, Gu X, Liu X, Zhang Y, Zhou Y
ACS applied materials & interfaces 2022 Oct 19;14(41):47052-47065
ACS applied materials & interfaces 2022 Oct 19;14(41):47052-47065
Pirfenidone ameliorates pulmonary inflammation and fibrosis in a rat silicosis model by inhibiting macrophage polarization and JAK2/STAT3 signaling pathways.
Tang Q, Xing C, Li M, Jia Q, Bo C, Zhang Z
Ecotoxicology and environmental safety 2022 Oct 1;244:114066
Ecotoxicology and environmental safety 2022 Oct 1;244:114066
Curcumin attenuates cadmium-induced atherosclerosis by regulating trimethylamine-N-oxide synthesis and macrophage polarization through remodeling the gut microbiota.
Zhang J, Ou C, Chen M
Ecotoxicology and environmental safety 2022 Oct 1;244:114057
Ecotoxicology and environmental safety 2022 Oct 1;244:114057
Chondroitin sulfate microspheres anchored with drug-loaded liposomes play a dual antioxidant role in the treatment of osteoarthritis.
He Y, Sun M, Wang J, Yang X, Lin C, Ge L, Ying C, Xu K, Liu A, Wu L
Acta biomaterialia 2022 Oct 1;151:512-527
Acta biomaterialia 2022 Oct 1;151:512-527
An increase in Semaphorin 3A biases the axonal direction and induces an aberrant dendritic arborization in an in vitro model of human neural progenitor differentiation.
Ferretti G, Romano A, Sirabella R, Serafini S, Maier TJ, Matrone C
Cell & bioscience 2022 Nov 8;12(1):182
Cell & bioscience 2022 Nov 8;12(1):182
Enhanced Immunotherapy Based on Combining the Pro-phagocytosis and Anti-phagocytosis Checkpoint Blockade for Tumor Eradication.
Song W, Yang F, Yang H, Xu Y, Song SJ, Meng Y, Wei ST, Wan T, Zhou Y, Zhou B, Kuang J, Yu T, Qiu WX
Journal of medicinal chemistry 2022 Nov 10;65(21):14832-14842
Journal of medicinal chemistry 2022 Nov 10;65(21):14832-14842
Microglia-derived TNF-α inhibiting GABAergic neurons in the anterior lateral bed nucleus of the stria terminalis precipitates visceral hypersensitivity induced by colorectal distension in rats.
Ji NN, Meng QX, Wang Y, Zhou ZM, Song Y, Hua R, Zhang YM
Neurobiology of stress 2022 May;18:100449
Neurobiology of stress 2022 May;18:100449
Exercise-induced neuroprotection against cerebral ischemia/reperfusion injury is mediated via alleviating inflammasome-induced pyroptosis.
Liu MX, Luo L, Fu JH, He JY, Chen MY, He ZJ, Jia J
Experimental neurology 2022 Mar;349:113952
Experimental neurology 2022 Mar;349:113952
Integrated analysis reveals the molecular features of fibrosis in triple-negative breast cancer.
Ding JH, Xiao Y, Zhao S, Xu Y, Xiao YL, Shao ZM, Jiang YZ, Di GH
Molecular therapy oncolytics 2022 Mar 17;24:624-635
Molecular therapy oncolytics 2022 Mar 17;24:624-635
Photosynthetic microorganisms coupled photodynamic therapy for enhanced antitumor immune effect.
Wang H, Liu H, Guo Y, Zai W, Li X, Xiong W, Zhao X, Yao Y, Hu Y, Zou Z, Wu J
Bioactive materials 2022 Jun;12:97-106
Bioactive materials 2022 Jun;12:97-106
Thiamine pretreatment improves endotoxemia-related liver injury and cholestatic complications by regulating galactose metabolism and inhibiting macrophage activation.
Li T, Bai J, Du Y, Tan P, Zheng T, Chen Y, Cheng Y, Cai T, Huang M, Fu W, Wen J
International immunopharmacology 2022 Jul;108:108892
International immunopharmacology 2022 Jul;108:108892
Embryonic stem cell-derived mesenchymal stem cells alleviate skeletal muscle injury induced by acute compartment syndrome.
Jiang X, Yang J, Liu F, Tao J, Xu J, Zhang M
Stem cell research & therapy 2022 Jul 15;13(1):313
Stem cell research & therapy 2022 Jul 15;13(1):313
Establishment of an Artificial Neural Network Model Using Immune-Infiltration Related Factors for Endometrial Receptivity Assessment.
Li B, Duan H, Wang S, Wu J, Li Y
Vaccines 2022 Jan 18;10(2)
Vaccines 2022 Jan 18;10(2)
Incorporation of magnesium oxide nanoparticles into electrospun membranes improves pro-angiogenic activity and promotes diabetic wound healing.
Liu M, Wang R, Liu J, Zhang W, Liu Z, Lou X, Nie H, Wang H, Mo X, Abd-Elhamid AI, Zheng R, Wu J
Biomaterials advances 2022 Feb;133:112609
Biomaterials advances 2022 Feb;133:112609
Surface Coating of Pulmonary siRNA Delivery Vectors Enabling Mucus Penetration, Cell Targeting, and Intracellular Radical Scavenging for Enhanced Acute Lung Injury Therapy.
Zhu J, Guo M, Cui Y, Meng Y, Ding J, Zeng W, Zhou W
ACS applied materials & interfaces 2022 Feb 2;14(4):5090-5100
ACS applied materials & interfaces 2022 Feb 2;14(4):5090-5100
Caffeine treatment started before injury reduces hypoxic-ischemic white-matter damage in neonatal rats by regulating phenotypic microglia polarization.
Yang L, Yu X, Zhang Y, Liu N, Xue X, Fu J
Pediatric research 2022 Dec;92(6):1543-1554
Pediatric research 2022 Dec;92(6):1543-1554
Scorpion venom polypeptide governs alveolar macrophage M1/M2 polarization to alleviate pulmonary fibrosis.
Xu L, Zhang Y, Dai Q, Lin N, Guan T, Song X, Hong S
Tissue & cell 2022 Dec;79:101939
Tissue & cell 2022 Dec;79:101939
Sonosensitizer nanoplatform-mediated sonodynamic therapy induced immunogenic cell death and tumor immune microenvironment variation.
Zheng J, Sun Y, Long T, Yuan D, Yue S, Zhang N, Yang Z
Drug delivery 2022 Dec;29(1):1164-1175
Drug delivery 2022 Dec;29(1):1164-1175
TREM2 activation alleviates neural damage via Akt/CREB/BDNF signalling after traumatic brain injury in mice.
Yan J, Zhang Y, Wang L, Li Z, Tang S, Wang Y, Gu N, Sun X, Li L
Journal of neuroinflammation 2022 Dec 3;19(1):289
Journal of neuroinflammation 2022 Dec 3;19(1):289
An Injectable Hydrogel Scaffold Loaded with Dual-Drug/Sustained-Release PLGA Microspheres for the Regulation of Macrophage Polarization in the Treatment of Intervertebral Disc Degeneration.
Cheng H, Guo Q, Zhao H, Liu K, Kang H, Gao F, Guo J, Yuan X, Hu S, Li F, Yang Q, Fang Z
International journal of molecular sciences 2022 Dec 26;24(1)
International journal of molecular sciences 2022 Dec 26;24(1)
Artificial Intelligence-Assisted Bioinformatics, Microneedle, and Diabetic Wound Healing: A "New Deal" of an Old Drug.
Xue Y, Chen C, Tan R, Zhang J, Fang Q, Jin R, Mi X, Sun D, Xue Y, Wang Y, Xiong R, Lu H, Tan W
ACS applied materials & interfaces 2022 Aug 24;14(33):37396-37409
ACS applied materials & interfaces 2022 Aug 24;14(33):37396-37409
MEF2C promotes M1 macrophage polarization and Th1 responses.
Zhao X, Di Q, Liu H, Quan J, Ling J, Zhao Z, Xiao Y, Wu H, Wu Z, Song W, An H, Chen W
Cellular & molecular immunology 2022 Apr;19(4):540-553
Cellular & molecular immunology 2022 Apr;19(4):540-553
A positive feedback loop: RAD18-YAP-TGF-β between triple-negative breast cancer and macrophages regulates cancer stemness and progression.
Yan X, He Y, Yang S, Zeng T, Hua Y, Bao S, Yang F, Duan N, Sun C, Liang Y, Fu Z, Huang X, Li W, Yin Y
Cell death discovery 2022 Apr 12;8(1):196
Cell death discovery 2022 Apr 12;8(1):196
Cell-free fat extract attenuates osteoarthritis via chondrocytes regeneration and macrophages immunomodulation.
Jia Z, Kang B, Cai Y, Chen C, Yu Z, Li W, Zhang W
Stem cell research & therapy 2022 Apr 1;13(1):133
Stem cell research & therapy 2022 Apr 1;13(1):133
Receptor-Interacting Protein Kinase 3 Inhibition Prevents Cadmium-Mediated Macrophage Polarization and Subsequent Atherosclerosis via Maintaining Mitochondrial Homeostasis.
Zhang J, Feng W, Li M, Chen P, Ning X, Ou C, Chen M
Frontiers in cardiovascular medicine 2021;8:737652
Frontiers in cardiovascular medicine 2021;8:737652
Neu-P11 - a novel melatonin receptor agonist, could improve the features of type-2 diabetes mellitus in rats.
Li X, He J, Li X, Li Y, Zhou Y, Cai S
Endokrynologia Polska 2021;72(6):634-642
Endokrynologia Polska 2021;72(6):634-642
P4HA1 Down-Regulation Inhibits Glioma Invasiveness by Promoting M1 Microglia Polarization.
Wang Q, Zhang J, Fang S, Wang J, Han X, Liu F, Jin G
OncoTargets and therapy 2021;14:1771-1782
OncoTargets and therapy 2021;14:1771-1782
Pentraxin-3 inhibits milky spots metastasis of gastric cancer by inhibiting M2 macrophage polarization.
Cui X, Qin T, Zhao Z, Yang G, Sanches JGP, Zhang Q, Fan S, Cao L, Hu X
Journal of Cancer 2021;12(15):4686-4697
Journal of Cancer 2021;12(15):4686-4697
Bacterial navigation for tumor targeting and photothermally-triggered bacterial ghost transformation for spatiotemporal drug release.
Xie S, Zhang P, Zhang Z, Liu Y, Chen M, Li S, Li X
Acta biomaterialia 2021 Sep 1;131:172-184
Acta biomaterialia 2021 Sep 1;131:172-184
Donor BMSC-derived small extracellular vesicles relieve acute rejection post-renal allograft through transmitting Loc108349490 to dendritic cells.
Wang ZG, Xu HE, Cheng FM, Zhang J, Feng YH, Liu DH, Shang WJ, Feng GW
Aging cell 2021 Oct;20(10):e13461
Aging cell 2021 Oct;20(10):e13461
Evaluation of immune status in testis and macrophage polarization associated with testicular damage in patients with nonobstructive azoospermia.
Zheng W, Zhang S, Jiang S, Huang Z, Chen X, Guo H, Li M, Zheng S
American journal of reproductive immunology (New York, N.Y. : 1989) 2021 Nov;86(5):e13481
American journal of reproductive immunology (New York, N.Y. : 1989) 2021 Nov;86(5):e13481
The Protective Role of Yin-Yang 1 in Cardiac Injury and Remodeling After Myocardial Infarction.
Huang Y, Li L, Chen H, Liao Q, Yang X, Yang D, Xia X, Wang H, Wang WE, Chen L, Zeng C
Journal of the American Heart Association 2021 Nov 2;10(21):e021895
Journal of the American Heart Association 2021 Nov 2;10(21):e021895
Ripened Pu-Erh Tea Improved the Enterohepatic Circulation in a Circadian Rhythm Disorder Mice Model.
Hu S, Chen Y, Zhao S, Sun K, Luo L, Zeng L
Journal of agricultural and food chemistry 2021 Nov 17;69(45):13533-13545
Journal of agricultural and food chemistry 2021 Nov 17;69(45):13533-13545
Splenic CD4(+) and CD8(+) T-cells highly expressed PD-1 and Tim-3 in cirrhotic patients with HCV infection and portal hypertension.
Huang N, Zhou R, Chen H, Zhang S, Li J, Wei W, Sun J, Ren S, Li B, Deng H, Yang J, Ji F, Li Z
International journal of immunopathology and pharmacology 2021 Jan-Dec;35:20587384211061051
International journal of immunopathology and pharmacology 2021 Jan-Dec;35:20587384211061051
Light-controlled oxygen production and collection for sustainable photodynamic therapy in tumor hypoxia.
Wang H, Guo Y, Wang C, Jiang X, Liu H, Yuan A, Yan J, Hu Y, Wu J
Biomaterials 2021 Feb;269:120621
Biomaterials 2021 Feb;269:120621
Astragalus polysacharin inhibits hepatocellular carcinoma-like phenotypes in a murine HCC model through repression of M2 polarization of tumour-associated macrophages.
Li C, Pan XY, Ma M, Zhao J, Zhao F, Lv YP
Pharmaceutical biology 2021 Dec;59(1):1533-1539
Pharmaceutical biology 2021 Dec;59(1):1533-1539
FNDC5 induces M2 macrophage polarization and promotes hepatocellular carcinoma cell growth by affecting the PPARγ/NF-κB/NLRP3 pathway.
Liu H, Wang M, Jin Z, Sun D, Zhu T, Liu X, Tan X, Shi G
Biochemical and biophysical research communications 2021 Dec 10;582:77-85
Biochemical and biophysical research communications 2021 Dec 10;582:77-85
The impact of ExHp-CD (outer membrane vesicles) released from Helicobacter pylori SS1 on macrophage RAW 264.7 cells and their immunogenic potential.
Ahmed AAQ, Qi F, Zheng R, Xiao L, Abdalla AME, Mao L, Bakadia BM, Liu L, Atta OM, Li X, Shi Z, Yang G
Life sciences 2021 Aug 15;279:119644
Life sciences 2021 Aug 15;279:119644
SCARF1 promotes M2 polarization of Kupffer cells via calcium-dependent PI3K-AKT-STAT3 signalling to improve liver transplantation.
Xu XS, Feng ZH, Cao D, Wu H, Wang MH, Li JZ, Gong JP
Cell proliferation 2021 Apr;54(4):e13022
Cell proliferation 2021 Apr;54(4):e13022
EB virus-induced ATR activation accelerates nasopharyngeal carcinoma growth via M2-type macrophages polarization.
Zhang B, Miao T, Shen X, Bao L, Zhang C, Yan C, Wei W, Chen J, Xiao L, Sun C, Du J, Li Y
Cell death & disease 2020 Sep 11;11(9):742
Cell death & disease 2020 Sep 11;11(9):742
Inhibiting HMGB1-RAGE axis prevents pro-inflammatory macrophages/microglia polarization and affords neuroprotection after spinal cord injury.
Fan H, Tang HB, Chen Z, Wang HQ, Zhang L, Jiang Y, Li T, Yang CF, Wang XY, Li X, Wu SX, Zhang GL
Journal of neuroinflammation 2020 Oct 9;17(1):295
Journal of neuroinflammation 2020 Oct 9;17(1):295
Comparison of reversal of rat pulmonary fibrosis of nintedanib, pirfenidone, and human umbilical mesenchymal stem cells from Wharton's jelly.
Chu KA, Yeh CC, Kuo FH, Lin WR, Hsu CW, Chen TH, Fu YS
Stem cell research & therapy 2020 Nov 30;11(1):513
Stem cell research & therapy 2020 Nov 30;11(1):513
A Comparison of Splenic Pathologic Change and Immune Function in HBV-Related Portal Hypertension and Chinese Budd-Chiari Syndrome Patients with Hypersplenism.
Li S, Huang N, Dang X, Li L, Li Z, Zhang C, Jiang A, Kong G, Ji F, Yang J, Li Z
Viral immunology 2020 Mar;33(2):112-121
Viral immunology 2020 Mar;33(2):112-121
Macrophage Spheroids with Chronological Phenotype Shifting To Promote Therapeutic Angiogenesis in Critical Limb Ischemia.
Ran P, Chen W, Wei J, Qiu B, Chen M, Xie S, Li X
ACS applied bio materials 2020 Jun 15;3(6):3707-3717
ACS applied bio materials 2020 Jun 15;3(6):3707-3717
Soluble epoxide hydrolase inhibition enhances anti-inflammatory and antioxidative processes, modulates microglia polarization, and promotes recovery after ischemic stroke.
Yeh CF, Chuang TY, Hung YW, Lan MY, Tsai CH, Huang HX, Lin YY
Neuropsychiatric disease and treatment 2019;15:2927-2941
Neuropsychiatric disease and treatment 2019;15:2927-2941
Electroacupuncture Pretreatment Alleviates Cerebral Ischemic Injury Through α7 Nicotinic Acetylcholine Receptor-Mediated Phenotypic Conversion of Microglia.
Ma Z, Zhang Z, Bai F, Jiang T, Yan C, Wang Q
Frontiers in cellular neuroscience 2019;13:537
Frontiers in cellular neuroscience 2019;13:537
High-Mobility Group Box 1 Contributes to Cerebral Cortex Injury in a Neonatal Hypoxic-Ischemic Rat Model by Regulating the Phenotypic Polarization of Microglia.
Sun Y, Hei M, Fang Z, Tang Z, Wang B, Hu N
Frontiers in cellular neuroscience 2019;13:506
Frontiers in cellular neuroscience 2019;13:506
Baicalein administered in the subacute phase ameliorates ischemia-reperfusion-induced brain injury by reducing neuroinflammation and neuronal damage.
Yang S, Wang H, Yang Y, Wang R, Wang Y, Wu C, Du G
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Sep;117:109102
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Sep;117:109102
Inhibition of microRNA-124a attenuates non-alcoholic fatty liver disease through upregulation of adipose triglyceride lipase and the effect of liraglutide intervention.
Fang QH, Shen QL, Li JJ, Yang Y, Guo JJ, Cheng Y, Zhou HC, Niu WY, Chen LM, Li CJ, Sun B
Hepatology research : the official journal of the Japan Society of Hepatology 2019 Jul;49(7):743-757
Hepatology research : the official journal of the Japan Society of Hepatology 2019 Jul;49(7):743-757
KDM3A inhibition modulates macrophage polarization to aggravate post-MI injuries and accelerates adverse ventricular remodeling via an IRF4 signaling pathway.
Liu X, Chen J, Zhang B, Liu G, Zhao H, Hu Q
Cellular signalling 2019 Dec;64:109415
Cellular signalling 2019 Dec;64:109415
C1q/TNF-related protein-9 promotes macrophage polarization and improves cardiac dysfunction after myocardial infarction.
Liu M, Yin L, Li W, Hu J, Wang H, Ye B, Tang Y, Huang C
Journal of cellular physiology 2019 Aug;234(10):18731-18747
Journal of cellular physiology 2019 Aug;234(10):18731-18747
Prolonged release of bone morphogenetic protein-2 in vivo by gene transfection with DNA-functionalized calcium phosphate nanoparticle-loaded collagen scaffolds.
Tenkumo T, Vanegas Sáenz JR, Nakamura K, Shimizu Y, Sokolova V, Epple M, Kamano Y, Egusa H, Sugaya T, Sasaki K
Materials science & engineering. C, Materials for biological applications 2018 Nov 1;92:172-183
Materials science & engineering. C, Materials for biological applications 2018 Nov 1;92:172-183
Hydrogel derived from porcine decellularized nerve tissue as a promising biomaterial for repairing peripheral nerve defects.
Lin T, Liu S, Chen S, Qiu S, Rao Z, Liu J, Zhu S, Yan L, Mao H, Zhu Q, Quan D, Liu X
Acta biomaterialia 2018 Jun;73:326-338
Acta biomaterialia 2018 Jun;73:326-338
Cathelicidin-WA polarizes E. coli K88-induced M1 macrophage to M2-like macrophage in RAW264.7 cells.
Chen S, Lu Z, Wang F, Wang Y
International immunopharmacology 2018 Jan;54:52-59
International immunopharmacology 2018 Jan;54:52-59
Photobiomodulation therapy promotes neurogenesis by improving post-stroke local microenvironment and stimulating neuroprogenitor cells.
Yang L, Tucker D, Dong Y, Wu C, Lu Y, Li Y, Zhang J, Liu TC, Zhang Q
Experimental neurology 2018 Jan;299(Pt A):86-96
Experimental neurology 2018 Jan;299(Pt A):86-96
TSG-6 attenuates inflammation-induced brain injury via modulation of microglial polarization in SAH rats through the SOCS3/STAT3 pathway.
Li R, Liu W, Yin J, Chen Y, Guo S, Fan H, Li X, Zhang X, He X, Duan C
Journal of neuroinflammation 2018 Aug 20;15(1):231
Journal of neuroinflammation 2018 Aug 20;15(1):231
Treadmill Exercise Exerts Neuroprotection and Regulates Microglial Polarization and Oxidative Stress in a Streptozotocin-Induced Rat Model of Sporadic Alzheimer's Disease.
Lu Y, Dong Y, Tucker D, Wang R, Ahmed ME, Brann D, Zhang Q
Journal of Alzheimer's disease : JAD 2017;56(4):1469-1484
Journal of Alzheimer's disease : JAD 2017;56(4):1469-1484
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The CD86 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human CD86. This antibody recognizes human antigen. The CD86 antibody has been validated for the following applications: ELISA, WB analysis.