FAB141P-100

antibody from R&D Systems

Targeting: CD86 B7-2, B7.2, CD28LG2

Flow cytometry (Supportive data in Antibodypedia)

Antibody Data

Product number

FAB141P-100

Provider

R&D Systems

Product name

Human B7-2/CD86 PE-conjugated Antibody

Antibody type

Monoclonal

Description

Protein A or G purified from ascites. Detects human B7-2/CD86 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) B7-1, recombinant mouse B7-2, recombinant rat B7-2, rhB7-H1, rhB7-H2, rhB7-H3, rhB7-H3b, rhB7-H4, or rhB7-L2 is observed.

Reactivity

Human

Host

Mouse

Isotype

IgG

Antibody clone number

37301

Vial size

100 Tests

Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied.

References

Submitted references

Signaling Lymphocyte Activation Molecule Family 5 Enhances Autophagy and Fine-Tunes Cytokine Response in Monocyte-Derived Dendritic Cells via Stabilization of Interferon Regulatory Factor 8.

Agod Z, Pazmandi K, Bencze D, Vereb G, Biro T, Szabo A, Rajnavolgyi E, Bacsi A, Engel P, Lanyi A
Frontiers in immunology 2018;9:62

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Focal Adhesion Kinase and ROCK Signaling Are Switch-Like Regulators of Human Adipose Stem Cell Differentiation towards Osteogenic and Adipogenic Lineages.

Hyväri L, Ojansivu M, Juntunen M, Kartasalo K, Miettinen S, Vanhatupa S
Stem cells international 2018;2018:2190657

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The effect of S53P4-based borosilicate glasses and glass dissolution products on the osteogenic commitment of human adipose stem cells.

Ojansivu M, Mishra A, Vanhatupa S, Juntunen M, Larionova A, Massera J, Miettinen S
PloS one 2018;13(8):e0202740

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Lactobacillus reuteri Surface Mucus Adhesins Upregulate Inflammatory Responses Through Interactions With Innate C-Type Lectin Receptors.

Bene KP, Kavanaugh DW, Leclaire C, Gunning AP, MacKenzie DA, Wittmann A, Young ID, Kawasaki N, Rajnavolgyi E, Juge N
Frontiers in microbiology 2017;8:321

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Regulation of type I interferon responses by mitochondria-derived reactive oxygen species in plasmacytoid dendritic cells.

Agod Z, Fekete T, Budai MM, Varga A, Szabo A, Moon H, Boldogh I, Biro T, Lanyi A, Bacsi A, Pazmandi K
Redox biology 2017 Oct;13:633-645

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Eosinophils induce DC maturation, regulating immunity.

Lotfi R, Lotze MT
Journal of leukocyte biology 2008 Mar;83(3):456-60

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Oxidation of ovarian epithelial cancer cells by hypochlorous acid enhances immunogenicity and stimulates T cells that recognize autologous primary tumor.

Chiang CL, Ledermann JA, Aitkens E, Benjamin E, Katz DR, Chain BM
Clinical cancer research : an official journal of the American Association for Cancer Research 2008 Aug 1;14(15):4898-907

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Decreased expression of tumor necrosis factor family receptors involved in humoral immune responses in preterm neonates.

Kaur K, Chowdhury S, Greenspan NS, Schreiber JR
Blood 2007 Oct 15;110(8):2948-54

Flow cytometry

Supportive validation

Submitted by

R&D Systems (provider)

Main image

Experimental details

Detection of B7-2/CD86 in Human Blood Monocytes by Flow Cytometry. Human peripheral blood monocytes were stained with Mouse Anti-Human CD14 APC-conjugated Monoclonal Antibody (Catalog # FAB3832A) and either (A) Mouse Anti-Human B7-2/CD86 PE-conjugated Monoclonal Antibody (Catalog # FAB141P) or (B) Mouse IgG₁ Phycoerythrin Isotype Control (Catalog # IC002P). View our protocol for Staining Membrane-associated Proteins.