305423

antibody from BioLegend
Targeting: CD86 B7-2, B7.2, CD28LG2
Provider product page for 305423

Antibody data

Product number
305423 - Provider product page
Provider
BioLegend
Proper citation
BioLegend Cat#305423, RRID:AB_2260067
Product name
Pacific Blue™ anti-human CD86 [IT2.2]
Antibody type
Monoclonal
Antigen
CD86
Description
CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, monocytes/macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is the ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce costimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.
Reactivity
Human, Simian
Host
Mouse
Conjugate
Blue dye
Isotype
IgG
Vial size
100 tests
Storage
The CD86 antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
CD86 protein structure - 305423 shown in red.