Explore
Validate
Learn
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [16]
- Comments [0]
- Validations
- Western blot [2]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 25818-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- c-Cbl antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated c-Cbl antibody (Cat. #25818-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references LncRNA AL645608.3 mediates malignant progression of acute myeloid leukemia.
c-Cbl induced podocin ubiquitination contributes to the podocytes injury in diabetic nephropathy.
ECHDC2 inhibits the proliferation of gastric cancer cells by binding with NEDD4 to degrade MCCC2 and reduce aerobic glycolysis.
AKIP1 accelerates glioblastoma progression through stabilizing EGFR expression.
Gasdermin E regulates the stability and activation of EGFR in human non-small cell lung cancer cells.
SERPINA5 promotes tumour cell proliferation by modulating the PI3K/AKT/mTOR signalling pathway in gastric cancer.
ZC3H15 promotes glioblastoma progression through regulating EGFR stability.
The ubiquitination of CKIP-1 mediated by Src aggravates diabetic renal fibrosis (original article).
Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.
ORP5 promotes tumor metastasis via stabilizing c-Met in renal cell carcinoma.
Cbl-b modulated TrkA ubiquitination and function in the dorsal root ganglion of mice.
Imatinib co-loaded targeted realgar nanocrystal for synergistic therapy of chronic myeloid leukemia.
Quantitative proteomics identifies PTP1B as modulator of B cell antigen receptor signaling.
JAC1 suppresses proliferation of breast cancer through the JWA/p38/SMURF1/HER2 signaling.
Salidroside-Mediated Autophagic Targeting of Active Src and Caveolin-1 Suppresses Low-Density Lipoprotein Transcytosis across Endothelial Cells.
CD2-Associated Protein Contributes to Hepatitis C, Virus Propagation and Steatosis by Disrupting Insulin Signaling.
Yan JH, Liao KQ, Yao L, Chen JL, Xiong LF, Tao XZ
American journal of translational research 2024;16(1):342-355
American journal of translational research 2024;16(1):342-355
c-Cbl induced podocin ubiquitination contributes to the podocytes injury in diabetic nephropathy.
Liang L, He M, Zhou P, Pan S, Chen J, Lv L, Hu M, Zhou S, Liu D, Liu Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 May 31;38(10):e23662
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 May 31;38(10):e23662
ECHDC2 inhibits the proliferation of gastric cancer cells by binding with NEDD4 to degrade MCCC2 and reduce aerobic glycolysis.
He J, Yi J, Ji L, Dai L, Chen Y, Xue W
Molecular medicine (Cambridge, Mass.) 2024 May 23;30(1):69
Molecular medicine (Cambridge, Mass.) 2024 May 23;30(1):69
AKIP1 accelerates glioblastoma progression through stabilizing EGFR expression.
Wan S, Liu C, Li C, Wang Z, Zhao G, Li J, Ran W, Zhong X, Li Y, Zhang L, Cui H
Oncogene 2023 Sep;42(39):2905-2918
Oncogene 2023 Sep;42(39):2905-2918
Gasdermin E regulates the stability and activation of EGFR in human non-small cell lung cancer cells.
Xu L, Shi F, Wu Y, Yao S, Wang Y, Jiang X, Su L, Liu X
Cell communication and signaling : CCS 2023 Apr 21;21(1):83
Cell communication and signaling : CCS 2023 Apr 21;21(1):83
SERPINA5 promotes tumour cell proliferation by modulating the PI3K/AKT/mTOR signalling pathway in gastric cancer.
Fan M, Xiong X, Han L, Zhang L, Gao S, Liu L, Wang X, Huang C, Tong D, Yang J, Zhao L, Shao Y
Journal of cellular and molecular medicine 2022 Sep;26(18):4837-4846
Journal of cellular and molecular medicine 2022 Sep;26(18):4837-4846
ZC3H15 promotes glioblastoma progression through regulating EGFR stability.
Hou J, Xu M, Gu H, Pei D, Liu Y, Huang P, Chang H, Cui H
Cell death & disease 2022 Jan 13;13(1):55
Cell death & disease 2022 Jan 13;13(1):55
The ubiquitination of CKIP-1 mediated by Src aggravates diabetic renal fibrosis (original article).
Yang Y, Xiao H, Lin Z, Chen R, Li S, Li C, Sun X, Hei Z, Gong W, Huang H
Biochemical pharmacology 2022 Dec;206:115339
Biochemical pharmacology 2022 Dec;206:115339
Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.
Li H, Zhang J, Ke JR, Yu Z, Shi R, Gao SS, Li JF, Gao ZX, Ke CS, Han HX, Xu J, Leng Q, Wu GR, Li Y, Tao L, Zhang X, Sy MS, Li C
Cell reports 2022 Dec 20;41(12):111834
Cell reports 2022 Dec 20;41(12):111834
ORP5 promotes tumor metastasis via stabilizing c-Met in renal cell carcinoma.
Song L, Zhang L, Zhou Y, Shao X, Xu Y, Pei D, Wang Q
Cell death discovery 2022 Apr 21;8(1):219
Cell death discovery 2022 Apr 21;8(1):219
Cbl-b modulated TrkA ubiquitination and function in the dorsal root ganglion of mice.
Chen HK, Li YZ, Ge AN, Zhu YB, Wu SJ, Bai X, Bai HH, Liu YN
European journal of pharmacology 2022 Apr 15;921:174876
European journal of pharmacology 2022 Apr 15;921:174876
Imatinib co-loaded targeted realgar nanocrystal for synergistic therapy of chronic myeloid leukemia.
Wang S, Liu X, Wang S, Ouyang L, Li H, Ding J, Deng G, Zhou W
Journal of controlled release : official journal of the Controlled Release Society 2021 Oct 10;338:190-200
Journal of controlled release : official journal of the Controlled Release Society 2021 Oct 10;338:190-200
Quantitative proteomics identifies PTP1B as modulator of B cell antigen receptor signaling.
Schwarz JJ, Grundmann L, Kokot T, Kläsener K, Fotteler S, Medgyesi D, Köhn M, Reth M, Warscheid B
Life science alliance 2021 Nov;4(11)
Life science alliance 2021 Nov;4(11)
JAC1 suppresses proliferation of breast cancer through the JWA/p38/SMURF1/HER2 signaling.
Ren Y, Chen D, Zhai Z, Chen J, Li A, Liang Y, Zhou J
Cell death discovery 2021 Apr 19;7(1):85
Cell death discovery 2021 Apr 19;7(1):85
Salidroside-Mediated Autophagic Targeting of Active Src and Caveolin-1 Suppresses Low-Density Lipoprotein Transcytosis across Endothelial Cells.
Bai X, Jia X, Lu Y, Zhu L, Zhao Y, Cheng W, Shu M, Jin S
Oxidative medicine and cellular longevity 2020;2020:9595036
Oxidative medicine and cellular longevity 2020;2020:9595036
CD2-Associated Protein Contributes to Hepatitis C, Virus Propagation and Steatosis by Disrupting Insulin Signaling.
Zhang H, Zhang C, Tang H, Gao S, Sun F, Yang Y, Zhou W, Hu Y, Ke C, Wu Y, Ding Z, Guo L, Pei R, Chen X, Sy MS, Zhang B, Li C
Hepatology (Baltimore, Md.) 2018 Nov;68(5):1710-1725
Hepatology (Baltimore, Md.) 2018 Nov;68(5):1710-1725
No comments: Submit comment
Supportive validation
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The CBL antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human CBL. This antibody recognizes human, mouse antigen. The CBL antibody has been validated for the following applications: ELISA, WB analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse spleen tissue were subjected to SDS PAGE followed by western blot with 25818-1-AP( CBL Antibody) at dilution of 1:1000
- Other comments
- WB
