ABIN362480

antibody from antibodies-online

Targeting: CBL c-Cbl, CBL2, RNF55

Immunocytochemistry (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN362480

Provider

antibodies-online

Product name

anti-Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) (pTyr770) antibody

Antibody type

Polyclonal

Antigen

Peptide sequence around phosphorylation site of pTyr770 (T-E-Y (p) -M-T) derived from Human c-Cbl. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatography using non-phosphopeptide corresponding to the phosphorylation site.

Reactivity

Human

Host

Rabbit

Epitope

pTyr770

Isotype

IgG

Vial size

100 μL

Concentration

1 mg/mL

Storage

Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

References

Submitted references

Fas and Fas ligand interactions in malignant disease.

Owen-Schaub L, Chan H, Cusack JC, Roth J, Hill LL
International journal of oncology 2000 Jul;17(1):5-12

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Nix and Nip3 form a subfamily of pro-apoptotic mitochondrial proteins.

Chen G, Cizeau J, Vande Velde C, Park JH, Bozek G, Bolton J, Shi L, Dubik D, Greenberg A
The Journal of biological chemistry 1999 Jan 1;274(1):7-10

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c-Cbl: a regulator of T cell receptor-mediated signalling.

Thien CB, Langdon WY
Immunology and cell biology 1998 Oct;76(5):473-82

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Identification and characterization of a human homolog of the Schizosaccharomyces pombe ras-like gene YPT-3.

Drivas GT, Shih A, Coutavas EE, D'Eustachio P, Rush MG
Oncogene 1991 Jan;6(1):3-9