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- References [13]
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- Immunohistochemistry [1]
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- Product number
- 10808-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10808-1-AP, RRID:AB_2121604
- Product name
- IFNGR1 antibody
- Antibody type
- Polyclonal
- Description
- IFNGR1 antibody (Cat. #10808-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: FC, IHC, IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Silica-induced macrophage pyroptosis propels pulmonary fibrosis through coordinated activation of relaxin and osteoclast differentiation signaling to reprogram fibroblasts.
Interferon-γ in the tumor microenvironment promotes the expression of B7H4 in colorectal cancer cells, thereby inhibiting cytotoxic T cells.
Low doses of IFN-γ maintain self-renewal of leukemia stem cells in acute myeloid leukemia.
E3 ligase Trim35 inhibits LSD1 demethylase activity through K63-linked ubiquitination and enhances anti-tumor immunity in NSCLC.
MYC activation impairs cell-intrinsic IFNγ signaling and confers resistance to anti-PD1/PD-L1 therapy in lung cancer.
Human lung adenocarcinoma CD47 is upregulated by interferon-γ and promotes tumor metastasis.
Pro-efferocytic macrophage membrane biomimetic nanoparticles for the synergistic treatment of atherosclerosis via competition effect.
Interferon-γ resistance and immune evasion in glioma develop via Notch-regulated co-evolution of malignant and immune cells.
DENR controls JAK2 translation to induce PD-L1 expression for tumor immune evasion.
Loss of Optineurin Drives Cancer Immune Evasion via Palmitoylation-Dependent IFNGR1 Lysosomal Sorting and Degradation.
Impact of adipose tissue or umbilical cord derived mesenchymal stem cells on the immunogenicity of human cord blood derived endothelial progenitor cells.
Central Regulatory Role for SIN1 in Interferon γ (IFNγ) Signaling and Generation of Biological Responses.
Gene expression profiling of NF-1-associated and sporadic pilocytic astrocytoma identifies aldehyde dehydrogenase 1 family member L1 (ALDH1L1) as an underexpressed candidate biomarker in aggressive subtypes.
Tian J, Song D, Peng Y, Zhang J, Ma L, Chen Z, Liang L, Zhang Z, Yun X, Zhang L
Ecotoxicology and environmental safety 2024 Mar 15;273:116106
Ecotoxicology and environmental safety 2024 Mar 15;273:116106
Interferon-γ in the tumor microenvironment promotes the expression of B7H4 in colorectal cancer cells, thereby inhibiting cytotoxic T cells.
Jing ZL, Liu GL, Zhou N, Xu DY, Feng N, Lei Y, Ma LL, Tang MS, Tong GH, Tang N, Deng YJ
Scientific reports 2024 Mar 13;14(1):6053
Scientific reports 2024 Mar 13;14(1):6053
Low doses of IFN-γ maintain self-renewal of leukemia stem cells in acute myeloid leukemia.
Xie X, Zhang W, Zhou X, Xu B, Wang H, Qiu Y, Hu Y, Guo B, Ye Z, Hu L, Zhang H, Li Y, Bai X
Oncogene 2023 Dec;42(50):3657-3669
Oncogene 2023 Dec;42(50):3657-3669
E3 ligase Trim35 inhibits LSD1 demethylase activity through K63-linked ubiquitination and enhances anti-tumor immunity in NSCLC.
Tang F, Lu C, He X, Lin W, Xie B, Gao X, Peng Y, Yang D, Sun L, Weng L
Cell reports 2023 Dec 26;42(12):113477
Cell reports 2023 Dec 26;42(12):113477
MYC activation impairs cell-intrinsic IFNγ signaling and confers resistance to anti-PD1/PD-L1 therapy in lung cancer.
Alburquerque-Bejar JJ, Navajas-Chocarro P, Saigi M, Ferrero-Andres A, Morillas JM, Vilarrubi A, Gomez A, Mate JL, Munoz-Marmol AM, Romero OA, Blecua P, Davalos V, Esteller M, Pros E, Llabata P, Torres-Diz M, Esteve-Codina A, Sanchez-Cespedes M
Cell reports. Medicine 2023 Apr 18;4(4):101006
Cell reports. Medicine 2023 Apr 18;4(4):101006
Human lung adenocarcinoma CD47 is upregulated by interferon-γ and promotes tumor metastasis.
Qu S, Jiao Z, Lu G, Xu J, Yao B, Wang T, Wang J, Yao Y, Yan X, Wang T, Liang H, Zen K
Molecular therapy oncolytics 2022 Jun 16;25:276-287
Molecular therapy oncolytics 2022 Jun 16;25:276-287
Pro-efferocytic macrophage membrane biomimetic nanoparticles for the synergistic treatment of atherosclerosis via competition effect.
Sha X, Dai Y, Chong L, Wei M, Xing M, Zhang C, Li J
Journal of nanobiotechnology 2022 Dec 1;20(1):506
Journal of nanobiotechnology 2022 Dec 1;20(1):506
Interferon-γ resistance and immune evasion in glioma develop via Notch-regulated co-evolution of malignant and immune cells.
Parmigiani E, Ivanek R, Rolando C, Hafen K, Turchinovich G, Lehmann FM, Gerber A, Brkic S, Frank S, Meyer SC, Wakimoto H, Günel M, Louvi A, Mariani L, Finke D, Holländer G, Hutter G, Tussiwand R, Taylor V, Giachino C
Developmental cell 2022 Aug 8;57(15):1847-1865.e9
Developmental cell 2022 Aug 8;57(15):1847-1865.e9
DENR controls JAK2 translation to induce PD-L1 expression for tumor immune evasion.
Chen B, Hu J, Hu X, Chen H, Bao R, Zhou Y, Ye Y, Zhan M, Cai W, Li H, Li HB
Nature communications 2022 Apr 19;13(1):2059
Nature communications 2022 Apr 19;13(1):2059
Loss of Optineurin Drives Cancer Immune Evasion via Palmitoylation-Dependent IFNGR1 Lysosomal Sorting and Degradation.
Du W, Hua F, Li X, Zhang J, Li S, Wang W, Zhou J, Wang W, Liao P, Yan Y, Li G, Wei S, Grove S, Vatan L, Zgodziński W, Majewski M, Wallner G, Chen H, Kryczek I, Fang JY, Zou W
Cancer discovery 2021 Jul;11(7):1826-1843
Cancer discovery 2021 Jul;11(7):1826-1843
Impact of adipose tissue or umbilical cord derived mesenchymal stem cells on the immunogenicity of human cord blood derived endothelial progenitor cells.
Tan K, Zheng K, Li D, Lu H, Wang S, Sun X
PloS one 2017;12(5):e0178624
PloS one 2017;12(5):e0178624
Central Regulatory Role for SIN1 in Interferon γ (IFNγ) Signaling and Generation of Biological Responses.
Kroczynska B, Blyth GT, Rafidi RL, Majchrzak-Kita B, Xu L, Saleiro D, Kosciuczuk EM, Jemielity J, Su B, Altman JK, Eklund EA, Fish EN, Platanias LC
The Journal of biological chemistry 2017 Mar 17;292(11):4743-4752
The Journal of biological chemistry 2017 Mar 17;292(11):4743-4752
Gene expression profiling of NF-1-associated and sporadic pilocytic astrocytoma identifies aldehyde dehydrogenase 1 family member L1 (ALDH1L1) as an underexpressed candidate biomarker in aggressive subtypes.
Rodriguez FJ, Giannini C, Asmann YW, Sharma MK, Perry A, Tibbetts KM, Jenkins RB, Scheithauer BW, Anant S, Jenkins S, Eberhart CG, Sarkaria JN, Gutmann DH
Journal of neuropathology and experimental neurology 2008 Dec;67(12):1194-204
Journal of neuropathology and experimental neurology 2008 Dec;67(12):1194-204
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HepG2 cells were subjected to SDS PAGE followed by western blot with 10808-1-AP(IFNGR1 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The IFNGR1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human IFNGR1. This antibody recognizes human antigen. The IFNGR1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
