IFNGR1

This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection. [provided by RefSeq, Jul 2008]

Description

interferon gamma receptor 1

Protein family

CD markers, Disease related genes, FDA approved drug targets, Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Predicted intracellular proteins, Predicted membrane proteins, Protein evidence (Peptideatlas)

Chromosome

6:q23.3 (137197484 - 137219449)

Ensembl ID

ENSG00000027697  (ver. 98.38)

Orthologs

Mouse Ifngr1: ENSMUSG00000020009

UniProt

P15260

neXtProt

NX_P15260

Human splice variants
Mouse splice variants