308703

antibody from BioLegend
Targeting: IFNGR1 CD119, IFNGR
Provider product page for 308703

Antibody data

Product number
308703 - Provider product page
Provider
BioLegend
Proper citation
BioLegend Cat#308703, RRID:AB_2121591
Product name
PE anti-human CD119 (IFN-‹ R ‡ chain)
Antibody type
Monoclonal
Antigen
Human IFN-γRα, purified from human placenta
Description
CDw119 is a 90-100 kD type I transmembrane protein, also known as IFN-γ R α chain or IFN-γRI. The IFN-γ receptor is a complex of a high affinity IFN-γ-binding chain (aka, IFN-γ R α chain) and a second accessory protein required for signal transduction known as IFN-γ R β chain. The IFN-γ R α chain is a member of the class II cytokine receptor family. Binding of IFN-γ induces receptor dimerization and internalization. Signal transduction involves Jak1 and Jak2 protein kinases and involves STAT1 activation. The IFN-γ receptor is expressed at moderate levels on virtually every cell with the exception of erythrocytes.
Reactivity
Human
Host
Mouse
Conjugate
Yellow dye
Isotype
IgG
Vial size
25 tests
Storage
The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
IFNGR1 protein structure - 308703 shown in red.