BAF400

antibody from R&D Systems

Targeting: IL1A IL-1A, IL1, IL1-ALPHA, IL1F1

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Antibody Data

Product number

BAF400

Provider

R&D Systems

Product name

Mouse IL-1 alpha/IL-1F1 Biotinylated Antibody

Antibody type

Polyclonal

Description

Antigen Affinity-purified. Detects mouse IL-1 alpha in ELISAs and Western blots. In sandwich immunoassays, less than 4% cross-reactivity with recombinant rat (rr) IL-1 alpha is observed and less than 0.5% cross-reactivity with rpIL-1 alpha and rhIL-1 alpha is observed.

Reactivity

Mouse

Host

Goat

Conjugate

Biotin

Antigen sequence

Q62161


Isotype

IgG

Vial size

50 ug

Concentration

LYOPH

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

References

Submitted references

A20 prevents inflammasome-dependent arthritis by inhibiting macrophage necroptosis through its ZnF7 ubiquitin-binding domain.

Polykratis A, Martens A, Eren RO, Shirasaki Y, Yamagishi M, Yamaguchi Y, Uemura S, Miura M, Holzmann B, Kollias G, Armaka M, van Loo G, Pasparakis M
Nature cell biology 2019 Jun;21(6):731-742

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Increased cytokine production in interleukin-18 receptor alpha-deficient cells is associated with dysregulation of suppressors of cytokine signaling.

Nold-Petry CA, Nold MF, Nielsen JW, Bustamante A, Zepp JA, Storm KA, Hong JW, Kim SH, Dinarello CA
The Journal of biological chemistry 2009 Sep 18;284(38):25900-11

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Resistance of human alveolar macrophages to Bacillus anthracis lethal toxin.

Wu W, Mehta H, Chakrabarty K, Booth JL, Duggan ES, Patel KB, Ballard JD, Coggeshall KM, Metcalf JP
Journal of immunology (Baltimore, Md. : 1950) 2009 Nov 1;183(9):5799-806