Tissue expression
Cell line expression
Protein structure
IL1A
Interleukin 1 alphaIL-1A, IL1, IL1-ALPHA, IL1F1
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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R&D Systems | ![]() |
14 references | Monoclonal |
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Invitrogen Antibodies | ![]() |
1 references | Polyclonal |
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Novus Biologicals | ![]() |
12 references | Polyclonal |
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LSBio | ![]() |
Monoclonal |
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Proteintech Group | ![]() |
36 references | Polyclonal |
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