500107

antibody from BioLegend

Targeting: IL1A IL-1A, IL1, IL1-ALPHA, IL1F1

Flow cytometry (Supportive data in Antibodypedia)

Antibody Data

Product number

500107

Provider

BioLegend

Proper citation

BioLegend Cat#500107, RRID:AB_315086

Product name

PE anti-human IL-1‡

Antibody type

Monoclonal

Antigen

Recombinant human IL-1α

Description

IL-1 refers to two proteins, IL-1α and IL-1β which are the products of distinct genes, but which are recognized by the same cell surface receptors. IL-1α is a potent immuno-modulator which mediates a wide range of immune and inflammatory responses. The 364-3B3-14 antibody reacts with human interleukin-1α (IL-1α). The 364-3B3-14 antibody is a non-neutralizing antibody.

Reactivity

Human, Simian

Host

Mouse

Conjugate

Yellow dye

Isotype

IgG

Vial size

50 µg

Concentration

0.2 mg/ml

Storage

The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

References

Submitted references

Rationale and efficacy of interleukin-1 targeting in Erdheim-Chester disease.

Aouba A, Georgin-Lavialle S, Pagnoux C, Martin Silva N, Renand A, Galateau-Salle F, Le Toquin S, Bensadoun H, Larousserie F, Silvera S, Provost N, Candon S, Seror R, de Menthon M, Hermine O, Guillevin L, Bienvenu B
Blood 2010 Nov 18;116(20):4070-6

Flow cytometry

Supportive validation

Submitted by

BioLegend (provider)

Main image

Experimental details

LPS-stimulated (6 hours) human peripheral blood monocytes surface stained with CD14 APC and intracellular stained with 364-3B3-14 PE

Conjugate

Yellow dye