Antibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations
- Flow cytometry [1]
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Validation data
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- Product number
- 500107 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#500107, RRID:AB_315086
- Product name
- PE anti-human IL-1
- Antibody type
- Monoclonal
- Antigen
- Recombinant human IL-1α
- Description
- IL-1 refers to two proteins, IL-1α and IL-1β which are the products of distinct genes, but which are recognized by the same cell surface receptors. IL-1α is a potent immuno-modulator which mediates a wide range of immune and inflammatory responses. The 364-3B3-14 antibody reacts with human interleukin-1α (IL-1α). The 364-3B3-14 antibody is a non-neutralizing antibody.
- Reactivity
- Human, Simian
- Host
- Mouse
- Conjugate
- Yellow dye
- Isotype
- IgG
- Vial size
- 50 µg
- Concentration
- 0.2 mg/ml
- Storage
- The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Submitted references Rationale and efficacy of interleukin-1 targeting in Erdheim-Chester disease.
Aouba A, Georgin-Lavialle S, Pagnoux C, Martin Silva N, Renand A, Galateau-Salle F, Le Toquin S, Bensadoun H, Larousserie F, Silvera S, Provost N, Candon S, Seror R, de Menthon M, Hermine O, Guillevin L, Bienvenu B
Blood 2010 Nov 18;116(20):4070-6
Blood 2010 Nov 18;116(20):4070-6
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Supportive validation
- Submitted by
- BioLegend (provider)
- Main image
- Experimental details
- LPS-stimulated (6 hours) human peripheral blood monocytes surface stained with CD14 APC and intracellular stained with 364-3B3-14 PE
- Conjugate
- Yellow dye