Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Flow cytometry [1]
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Validation data
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- Product number
- FAB230P-100 - Provider product page
- Provider
- R&D Systems
- Product name
- Human IL-4R alpha PE-conjugated Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from ascites. Detects human IL-4 R alpha in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) IL-9 R, recombinant mouse IL-4 R, rhIL-5 R alpha , rhIL-5 R beta , rhIL-13 R alpha 1, or rhIL-13 R alpha 2 is observed.
- Reactivity
- Human
- Host
- Mouse
- Antigen sequence
P24394
- Isotype
- IgG
- Antibody clone number
- 25463
- Vial size
- 100 Tests
- Storage
- Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied.
Submitted references Chimeric rat/human HER2 efficiently circumvents HER2 tolerance in cancer patients.
IL4Ralpha+ myeloid-derived suppressor cell expansion in cancer patients.
MEK1/2 induces STAT5-mediated germline transcription of the TCRgamma locus in response to IL-7R signaling.
Occhipinti S, Sponton L, Rolla S, Caorsi C, Novarino A, Donadio M, Bustreo S, Satolli MA, Pecchioni C, Marchini C, Amici A, Cavallo F, Cappello P, Pierobon D, Novelli F, Giovarelli M
Clinical cancer research : an official journal of the American Association for Cancer Research 2014 Jun 1;20(11):2910-21
Clinical cancer research : an official journal of the American Association for Cancer Research 2014 Jun 1;20(11):2910-21
IL4Ralpha+ myeloid-derived suppressor cell expansion in cancer patients.
Mandruzzato S, Solito S, Falisi E, Francescato S, Chiarion-Sileni V, Mocellin S, Zanon A, Rossi CR, Nitti D, Bronte V, Zanovello P
Journal of immunology (Baltimore, Md. : 1950) 2009 May 15;182(10):6562-8
Journal of immunology (Baltimore, Md. : 1950) 2009 May 15;182(10):6562-8
MEK1/2 induces STAT5-mediated germline transcription of the TCRgamma locus in response to IL-7R signaling.
Maki K, Ikuta K
Journal of immunology (Baltimore, Md. : 1950) 2008 Jul 1;181(1):494-502
Journal of immunology (Baltimore, Md. : 1950) 2008 Jul 1;181(1):494-502
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Supportive validation
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- R&D Systems (provider)
- Main image
- Experimental details
- Detection of IL-4 R alpha in Daudi Human Cell Line by Flow Cytometry. Daudi human Burkitt's lymphoma cell line was stained with Mouse Anti-Human IL-4 R alpha PE-conjugated Monoclonal Antibody (Catalog # FAB230P, filled histogram) or isotype control antibody (Catalog # IC003P, open histogram). View our protocol for Staining Membrane-associated Proteins.