Tissue expression
Cell line expression
Protein structure

IL4R

Interleukin 4 receptor
CD124 
This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2012]
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869 antibodies from 41 providers.

Antibody properties

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AntibodyRefsTypeWBELICCIPIHCFC
R&D Systems
21 antibodies
Novus Biologicals
79 antibodies
Invitrogen Antibodies
33 antibodies
OriGene
7 antibodies
antibodies-online
161 antibodies
Biorbyt
129 antibodies
GeneTex
4 antibodies
Cusabio Biotech Co., Ltd
4 antibodies
Proteintech Group
3 antibodies
Boster Biological Technology
3 antibodies
Affinity Biosciences
1 antibody
NSJ Bioreagents
2 antibodies
St John's Laboratory
6 antibodies
Aviva Systems Biology
3 antibodies
Wuhan Fine Biotech Co., Ltd.
1 antibody
Abnova Corporation
17 antibodies
Acris Antibodies GmbH
6 antibodies
Atlas Antibodies
1 antibody
Bioworld Technology, Inc
3 antibodies
PeproTech Inc.
6 antibodies
Abbkine Scientific Co.Ltd.
4 antibodies
Creative Biolabs
130 antibodies
BioLegend
13 antibodies
MyBioSource
7 antibodies
Abbexa
5 antibodies
Creative Diagnostics
3 antibodies
Abgent
1 antibody
ProSci
1 antibody
Santa Cruz Biotechnology
1 antibody
Miltenyi Biotec
6 antibodies
Abiocode, Inc.
3 antibodies
MilliporeSigma / Merck KGaA
7 antibodies
EMD Millipore
1 antibody
United States Biological
78 antibodies
eBioscience, An Affymetrix Company
3 antibodies
Leading Biology
1 antibody
Sino Biological Inc.
4 antibodies
RayBiotech, Inc.
2 antibodies
DIMA
1 antibody