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- Antibody Data
- Antigen structure
- References [3]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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- Product number
- ABIN1449670 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 5 (Double-Strand-Break Rejoining) (XRCC5) (C-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide from C-terminal region of Human Ku70/80
- Description
- Immunoaffinity Chromatography
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- C-Term
- Isotype
- IgG
- Vial size
- 50 μg
- Concentration
- 1.0 mg/mL
- Storage
- Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Biochemical evidence for Ku-independent backup pathways of NHEJ.
Ku stimulation of DNA ligase IV-dependent ligation requires inward movement along the DNA molecule.
Ku antigen-DNA conformation determines the activation of DNA-dependent protein kinase and DNA sequence-directed repression of mouse mammary tumor virus transcription.
Wang H, Perrault AR, Takeda Y, Qin W, Wang H, Iliakis G
Nucleic acids research 2003 Sep 15;31(18):5377-88
Nucleic acids research 2003 Sep 15;31(18):5377-88
Ku stimulation of DNA ligase IV-dependent ligation requires inward movement along the DNA molecule.
Kysela B, Doherty AJ, Chovanec M, Stiff T, Ameer-Beg SM, Vojnovic B, Girard PM, Jeggo PA
The Journal of biological chemistry 2003 Jun 20;278(25):22466-74
The Journal of biological chemistry 2003 Jun 20;278(25):22466-74
Ku antigen-DNA conformation determines the activation of DNA-dependent protein kinase and DNA sequence-directed repression of mouse mammary tumor virus transcription.
Giffin W, Gong W, Schild-Poulter C, Haché RJ
Molecular and cellular biology 1999 Jun;19(6):4065-78
Molecular and cellular biology 1999 Jun;19(6):4065-78
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of extracts from LOVO cells, using Ku70/80 Antibody Cat.-No AP32239PU-N. The lane on the right is treated with the synthesized peptide.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Immunofluorescence analysis of A549 cells, using Ku70/80 Antibody Cat.-No AP32239PU-N. The picture on the right is treated with the synthesized peptide.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
