Tissue expression
Cell line expression
Protein structure
XRCC5
X-ray repair cross complementing 5KARP-1, KU80, Ku86, KUB2
The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008]
Top validated antibodies |
|||||
Invitrogen Antibodies | MA5-12933 | 72 references | Monoclonal |
WB
ICC
IP
FC
OA
|
|
Proteintech Group | 16389-1-AP | 16 references | Polyclonal |
WB
EL
ICC
IP
IHC
|
|
antibodies-online | ABIN969463 | 2 references | Monoclonal |
WB
EL
ICC
IHC
FC
|
|
GeneTex | GTX109935 | 4 references | Polyclonal |
WB
ICC
IP
IHC |
|
Novus Biologicals | H00007520-M02 | 3 references | Monoclonal |
WB
EL
ICC
IHC |
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Supportive data in Antibodypedia
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Recommended by provider