66546-1-Ig

antibody from Proteintech Group

Targeting: XRCC5 KARP-1, KU80, Ku86, KUB2

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Immunoprecipitation (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

66546-1-Ig

Provider

Proteintech Group

Product name

XRCC5 antibody

Antibody type

Monoclonal

Description

XRCC5 antibody (Cat. #66546-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB, ELISA.

Reactivity

Human, Mouse, Rat

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

2G5E7

Vial size

20ul, 150ul

References

Submitted references

PCDHGB7 inhibits the progression of triple-negative breast cancer by suppressing XRCC5/MYC-mediated ribosome biogenesis.

Shan M, Bi H, Sun H, Li Y, Li Z, Wang Z, Dong J, Sang S, Ren L, Ye Y, Wang T, Volarević S, Su R, Zhang L, Zhang M, He Y, Zhang G, Li J, Li X
Clinical and translational medicine 2025 Sep;15(9):e70437

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Establishment and biological characterization of radioresistant colorectal cancer cell lines.

Qu TY, Dai Q, Leng J, Fang L, Ma JJ, Chen R, Chen C, Ran PF, Zhou WW, Liu C, Yu HF
FEBS open bio 2025 Jun;15(6):1009-1021

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Nuclear VPS35 attenuates NHEJ repair by sequestering Ku protein.

Zhang L, Nie Y, Tang T, Lu Y, Li W, Hong X, Li Q, Zheng A, Li Y, Zhou J, Fan L, Wang T, Deng Z
Molecular medicine (Cambridge, Mass.) 2025 Jun 9;31(1):222

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FAM21 interacts with Ku to promote the localization of WASH to DNA double strand break sites.

Wang T, Zheng AX, Li P, Tang T, Zhang LP, Hong Y, Hong X, Deng ZH
DNA repair 2024 Jan;133:103603

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Ku70 silencing aggravates oxygen-glucose deprivation/reperfusion-induced injury by activation of the p53 apoptotic pathway in rat cortical astrocytes.

Xie X, Liu J
Histochemistry and cell biology 2024 Dec 23;163(1):20

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Radiosensitization effect of quinoline-indole-schiff base derivative 10E on non-small cell lung cancer cells in vitro and in tumor xenografts.

Liu H, Wang Q, Lan W, Liu D, Huang J, Yao J
Investigational new drugs 2024 Aug;42(4):405-417

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Single nucleotide polymorphisms rs148582811 regulates its host gene ARVCF expression to affect nicotine-associated hippocampus-dependent memory.

Yang Z, Chen J, Han H, Wang Y, Shi X, Zhang B, Mao Y, Li AN, Yuan W, Yao J, Li MD
iScience 2023 Dec 15;26(12):108335

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Comparison of DNA stability and its related genes of neurons derived from induced pluripotent stem cells and primary retinal neurons.

Yu N, Qiu J, Li K, Luo Q, Liu X, Yang Y, Jiang Z, He S, He A, Chen S, Chen X, Li Y, Ge J, Zhuang J, Yu K
Cell biology international 2022 Oct;46(10):1625-1636

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ITGA2 overexpression inhibits DNA repair and confers sensitivity to radiotherapies in pancreatic cancer.

Zhou C, Li S, Bin K, Qin G, Pan P, Ren D, Zhao Y, Xia W, Chen J, Liu J, Wu H, Zhou Y
Cancer letters 2022 Oct 28;547:215855

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WASH interacts with Ku to regulate DNA double-stranded break repair.

Wang T, Du XH, Hong Y, Hong X, Fan L, Zhou JW, Sun H, Ge J, Billadeau DD, Deng ZH
iScience 2022 Jan 21;25(1):103676