Antibody data
- Antibody Data
- Antigen structure
- References [5]
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- Validations
- Western blot [3]
- ELISA [1]
- Immunohistochemistry [1]
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- Product number
- ABIN393709 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 5 (Double-Strand-Break Rejoining) (XRCC5) (AA 1-733) antibody
- Antibody type
- Monoclonal
- Description
- This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Mouse
- Epitope
- AA 1-733
- Isotype
- IgG
- Antibody clone number
- 3D8
- Vial size
- 100 μg
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Submitted references Comprehensive screen of genetic variation in DNA repair pathway genes and postmenopausal breast cancer risk.
A large-scale candidate gene approach identifies SNPs in SOD2 and IL13 as predictive markers of response to preoperative chemoradiation in rectal cancer.
Gamma-radiation sensitivity and polymorphisms in RAD51L1 modulate glioma risk.
The role of common variants of non-homologous end-joining repair genes XRCC4, LIG4 and Ku80 in thyroid cancer risk.
Variation within DNA repair pathway genes and risk of multiple sclerosis.
Monsees GM, Kraft P, Chanock SJ, Hunter DJ, Han J
Breast cancer research and treatment 2011 Jan;125(1):207-14
Breast cancer research and treatment 2011 Jan;125(1):207-14
A large-scale candidate gene approach identifies SNPs in SOD2 and IL13 as predictive markers of response to preoperative chemoradiation in rectal cancer.
Ho-Pun-Cheung A, Assenat E, Bascoul-Mollevi C, Bibeau F, Boissière-Michot F, Thezenas S, Cellier D, Azria D, Rouanet P, Senesse P, Ychou M, Lopez-Crapez E
The pharmacogenomics journal 2011 Dec;11(6):437-43
The pharmacogenomics journal 2011 Dec;11(6):437-43
Gamma-radiation sensitivity and polymorphisms in RAD51L1 modulate glioma risk.
Liu Y, Shete S, Wang LE, El-Zein R, Etzel CJ, Liang FW, Armstrong G, Tsavachidis S, Gilbert MR, Aldape KD, Xing J, Wu X, Wei Q, Bondy ML
Carcinogenesis 2010 Oct;31(10):1762-9
Carcinogenesis 2010 Oct;31(10):1762-9
The role of common variants of non-homologous end-joining repair genes XRCC4, LIG4 and Ku80 in thyroid cancer risk.
Gomes BC, Silva SN, Azevedo AP, Manita I, Gil OM, Ferreira TC, Limbert E, Rueff J, Gaspar JF
Oncology reports 2010 Oct;24(4):1079-85
Oncology reports 2010 Oct;24(4):1079-85
Variation within DNA repair pathway genes and risk of multiple sclerosis.
Briggs FB, Goldstein BA, McCauley JL, Zuvich RL, De Jager PL, Rioux JD, Ivinson AJ, Compston A, Hafler DA, Hauser SL, Oksenberg JR, Sawcer SJ, Pericak-Vance MA, Haines JL, Barcellos LF, International Multiple Sclerosis Genetics Consortium.
American journal of epidemiology 2010 Jul 15;172(2):217-24
American journal of epidemiology 2010 Jul 15;172(2):217-24
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Supportive validation
- Submitted by
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- IHC