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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- PAB4736 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB4736, RRID:AB_1576883
- Product name
- LRP6 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of LRP6.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references A novel mechanism for Wnt activation of canonical signaling through the LRP6 receptor.
LDL-receptor-related proteins in Wnt signal transduction.
Isolation and characterization of LRP6, a novel member of the low density lipoprotein receptor gene family.
Liu G, Bafico A, Harris VK, Aaronson SA
Molecular and cellular biology 2003 Aug;23(16):5825-35
Molecular and cellular biology 2003 Aug;23(16):5825-35
LDL-receptor-related proteins in Wnt signal transduction.
Tamai K, Semenov M, Kato Y, Spokony R, Liu C, Katsuyama Y, Hess F, Saint-Jeannet JP, He X
Nature 2000 Sep 28;407(6803):530-5
Nature 2000 Sep 28;407(6803):530-5
Isolation and characterization of LRP6, a novel member of the low density lipoprotein receptor gene family.
Brown SD, Twells RC, Hey PJ, Cox RD, Levy ER, Soderman AR, Metzker ML, Caskey CT, Todd JA, Hess JF
Biochemical and biophysical research communications 1998 Jul 30;248(3):879-88
Biochemical and biophysical research communications 1998 Jul 30;248(3):879-88
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of LRP6 (arrow) using rabbit LRP6 polyclonal antibody (Cat # PAB4736). 293 cell lysate (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the LRP6 gene (Lane 2) (Origene Technologies).
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with LRP6 polyclonal antibody (Cat # PAB4736) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
