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- Antibody Data
- Antigen structure
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- Product number
- abx032705 - Provider product page
- Provider
- Abbexa
- Product name
- Low Density Lipoprotein Receptor Related Protein 6 (LRP6) Antibody
- Antibody type
- Polyclonal
- Description
- LRP6 is essential for the Wnt/beta catenin signaling pathway, probably by acting as a coreceptor together with Frizzled for Wnt. It is a specific, high-affinity receptor for DKK1 and DKK2, but not DKK3. The interaction with DKK1 blocks LRP6-mediated Wnt/beta catenin signaling via LRP6 removal via Kremen proteins-mediated endocytosis.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 80 µl
- Concentration
- 1.2 mg/ml
- Storage
- Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
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