M00706

antibody from Boster Biological Technology
Targeting: NTRK1 MTC, TRK, TRKA
Provider product page for M00706
Western blot
Immunocytochemistry

Antibody data

Product number
M00706 - Provider product page
Provider
Boster Biological Technology
Product name
Anti-TrkA+B+C NTRK1 Rabbit Monoclonal Antibody
Antibody type
Monoclonal
Description
Monoclonal antibody for TrkA/NTRK1 detection. Host: Rabbit.Size: 100ug/vial. Tested applications: IF, IHC, ICC, WB. Reactive species: Human, Mouse, Rat TrkA/NTRK1 information: Molecular Weight: 87497 MW; Subcellular Localization: Cell membrane ; Single-pass type I membrane protein . Early endosome membrane ; Single-pass type I membrane protein . Late endosome membrane ; Single-pass type I membrane protein . Internalized to endosomes upon binding of NGF or NTF3 and further transported to the cell body via a retrograde axonal transport. Localized at cell membrane and early endosomes before nerve growth factor (NGF) stimulation. Recruited to late endosomes after NGF stimulation. Colocalized with RAPGEF2 at late endosomes (By similarity); Tissue Specificity: Isoform TrkA-I is found in most non-neuronal tissues. Isoform TrkA-II is primarily expressed in neuronal cells. TrkA-III is specifically expressed by pluripotent neural stem and neural crest progenitors.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Antibody clone number
HHH-14
Vial size
100ug/vial
Concentration
0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Storage
At -20°C for one year. Avoid repeated freezing and thawing.
NTRK1 protein structure - M00706 shown in red.