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Cell line expression
Protein structure
NTRK1
Neurotrophic receptor tyrosine kinase 1MTC, TRK, TRKA
This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, cognitive disability and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Novus Biologicals |  AF175 |
11 references | Polyclonal |
WB
IHC
FC
BN
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| R&D Systems | AF175 |
9 references | Polyclonal |
WB
IHC
FC
BN
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| Boster Biological Technology | M00706-1 |
2 references | Monoclonal |
WB
ICC
IP
IHC
FC
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| LSBio | LS-C368452 |
Polyclonal |
WB
ICC
IHC
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| Invitrogen Antibodies | PA5-109216 |
1 references | Polyclonal |
WB
ICC
IHC
FC
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