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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [7]
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- Product number
- ABIN351063 - Provider product page
- Provider
- antibodies-online
- Proper citation
- Antibodies-Online Cat#ABIN351063, RRID:AB_10785427
- Product name
- anti-Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) (Extracellular Domain) antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide from the extracellular domain of human TrkA (High affinity nerve growth factor receptor, NTRK1, p140-TrkA, Trk-A) conjugated to an immunogenic carrier protein was used as the immunogen.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- Extracellular Domain
- Isotype
- IgG
- Vial size
- 500 μg
- Storage
- Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
- Handling
- Avoid freeze and thaw cycles.
Submitted references Methylation adjacent to negatively regulating AP-1 site reactivates TrkA gene expression during cancer progression.
Structure and organization of the human TRKA gene encoding a high affinity receptor for nerve growth factor.
A Trk nerve growth factor (NGF) receptor point mutation affecting interaction with phospholipase C-gamma 1 abolishes NGF-promoted peripherin induction but not neurite outgrowth.
The trk proto-oncogene encodes a receptor for nerve growth factor.
High-affinity NGF binding requires coexpression of the trk proto-oncogene and the low-affinity NGF receptor.
Molecular and biochemical characterization of the human trk proto-oncogene.
A human oncogene formed by the fusion of truncated tropomyosin and protein tyrosine kinase sequences.
Fujimoto M, Kitazawa R, Maeda S, Kitazawa S
Oncogene 2005 Jul 28;24(32):5108-18
Oncogene 2005 Jul 28;24(32):5108-18
Structure and organization of the human TRKA gene encoding a high affinity receptor for nerve growth factor.
Indo Y, Mardy S, Tsuruta M, Karim MA, Matsuda I
The Japanese journal of human genetics 1997 Jun;42(2):343-51
The Japanese journal of human genetics 1997 Jun;42(2):343-51
A Trk nerve growth factor (NGF) receptor point mutation affecting interaction with phospholipase C-gamma 1 abolishes NGF-promoted peripherin induction but not neurite outgrowth.
Loeb DM, Stephens RM, Copeland T, Kaplan DR, Greene LA
The Journal of biological chemistry 1994 Mar 25;269(12):8901-10
The Journal of biological chemistry 1994 Mar 25;269(12):8901-10
The trk proto-oncogene encodes a receptor for nerve growth factor.
Klein R, Jing SQ, Nanduri V, O'Rourke E, Barbacid M
Cell 1991 Apr 5;65(1):189-97
Cell 1991 Apr 5;65(1):189-97
High-affinity NGF binding requires coexpression of the trk proto-oncogene and the low-affinity NGF receptor.
Hempstead BL, Martin-Zanca D, Kaplan DR, Parada LF, Chao MV
Nature 1991 Apr 25;350(6320):678-83
Nature 1991 Apr 25;350(6320):678-83
Molecular and biochemical characterization of the human trk proto-oncogene.
Martin-Zanca D, Oskam R, Mitra G, Copeland T, Barbacid M
Molecular and cellular biology 1989 Jan;9(1):24-33
Molecular and cellular biology 1989 Jan;9(1):24-33
A human oncogene formed by the fusion of truncated tropomyosin and protein tyrosine kinase sequences.
Martin-Zanca D, Hughes SH, Barbacid M
Nature 1986 Feb 27-Mar 5;319(6056):743-8
Nature 1986 Feb 27-Mar 5;319(6056):743-8
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