Antibody data
- Antibody Data
- Antigen structure
- References [55]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunoprecipitation [1]
- Immunohistochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 11117-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11117-1-AP, RRID:AB_2210113
- Product name
- TXNRD1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated TXNRD1 antibody (Cat. #11117-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references A new gold(I) phosphine complex induces apoptosis in prostate cancer cells by increasing reactive oxygen species.
Development and validation of a disulfidptosis and disulfide metabolism-related risk index for predicting prognosis in lung adenocarcinoma.
Melatonin antagonizes oxidative stress-induced apoptosis in retinal ganglion cells through activating the thioredoxin-1 pathway.
Arginase 2 attenuates ulcerative colitis by antioxidant effects of spermidine.
Ferroptosis in the colon epithelial cells as a therapeutic target for ulcerative colitis.
Tremella fuciformis polysaccharides alleviates UV-provoked skin cell damage via regulation of thioredoxin interacting protein and thioredoxin reductase 2.
Hypoxia-Induced Changes in L-Cysteine Metabolism and Antioxidative Processes in Melanoma Cells.
A prognostic risk model, tumor immune environment modulation, and drug prediction of ferroptosis and amino acid metabolism-related genes in hepatocellular carcinoma.
Nuclear Translocation of LDHA Promotes the Catabolism of BCAAs to Sustain GBM Cell Proliferation through the TxN Antioxidant Pathway.
An mRNA processing pathway suppresses metastasis by governing translational control from the nucleus.
Discovery of novel hydroxyamidine based indoleamine 2,3-dioxygenase 1 (IDO1) and thioredoxin reductase 1 (TrxR1) dual inhibitors.
The organic arsenical-derived thioredoxin and glutathione system inhibitor ACZ2 induces apoptosis and autophagy in gastric cancer via ROS-dependent ER stress.
TrxR/Trx inhibitor butaselen ameliorates pulmonary fibrosis by suppressing NF-κB/TGF-β1/Smads signaling.
Seven oxidative stress-related genes predict the prognosis of hepatocellular carcinoma.
Elovanoid-N34 modulates TXNRD1 key in protection against oxidative stress-related diseases.
SERD-NHC-Au(I) complexes for dual targeting ER and TrxR to induce ICD in breast cancer.
Metabolism-Related Gene TXNRD1 Regulates Inflammation and Oxidative Stress Induced by Cigarette Smoke through the Nrf2/HO-1 Pathway in the Small Airway Epithelium.
Fast regulation of the NF-κB signalling pathway in human skeletal muscle revealed by high-intensity exercise and ischaemia at exhaustion: Role of oxygenation and metabolite accumulation.
Selenium Deficiency Leads to Changes in Renal Fibrosis Marker Proteins and Wnt/β-Catenin Signaling Pathway Components.
Nanoparticle delivery of miR-21-3p sensitizes melanoma to anti-PD-1 immunotherapy by promoting ferroptosis.
Anti-Inflammatory Effect of Dimethyl Fumarate Associates with the Inhibition of Thioredoxin Reductase 1 in RAW 264.7 Cells.
The role of selenoproteins in neutrophils during inflammation.
Menadione Potentiates Auranofin-Induced Glioblastoma Cell Death.
Therapeutic Effects of an Inhibitor of Thioredoxin Reductase on Liver Fibrosis by Inhibiting the Transforming Growth Factor-β1/Smads Pathway.
Helenalin Facilitates Reactive Oxygen Species-Mediated Apoptosis and Cell Cycle Arrest by Targeting Thioredoxin Reductase-1 in Human Prostate Cancer Cells.
Mechanistic Analysis of an Extracellular Signal-Regulated Kinase 2-Interacting Compound that Inhibits Mutant BRAF-Expressing Melanoma Cells by Inducing Oxidative Stress.
Libertellenone H, a Natural Pimarane Diterpenoid, Inhibits Thioredoxin System and Induces ROS-Mediated Apoptosis in Human Pancreatic Cancer Cells.
Discovery of hydroxytyrosol as thioredoxin reductase 1 inhibitor to induce apoptosis and G(1)/S cell cycle arrest in human colorectal cancer cells via ROS generation.
Fasting Induces Hepatocellular Carcinoma Cell Apoptosis by Inhibiting SET8 Expression.
WHSC1 Promotes Cell Proliferation, Migration, and Invasion in Hepatocellular Carcinoma by Activating mTORC1 Signaling.
Synthesis and biological evaluation of gold(III) Schiff base complexes for the treatment of hepatocellular carcinoma through attenuating TrxR activity.
Synthesis and biological evaluation of myricetin-pentadienone hybrids as potential anti-inflammatory agents in vitro and in vivo.
A Gold(I) Complex Containing an Oleanolic Acid Derivative as a Potential Anti-Ovarian-Cancer Agent by Inhibiting TrxR and Activating ROS-Mediated ERS.
Targeting the MAPK/ERK and PI3K/AKT Signaling Pathways Affects NRF2, Trx and GSH Antioxidant Systems in Leukemia Cells.
The novel thioredoxin reductase inhibitor A-Z2 triggers intrinsic apoptosis and shows efficacy in the treatment of acute myeloid leukemia.
Design, synthesis, and biological evaluation of a novel indoleamine 2,3-dioxigenase 1 (IDO1) and thioredoxin reductase (TrxR) dual inhibitor.
miR-125b-5p inhibits cell proliferation, migration, and invasion in hepatocellular carcinoma via targeting TXNRD1.
Effects of KEAP1 Silencing on the Regulation of NRF2 Activity in Neuroendocrine Lung Tumors.
A novel iron(II) phenanthroline complex exhibits anticancer activity against TFR1-overexpressing esophageal squamous cell carcinoma cells through ROS accumulation and DNA damage.
Proscillaridin A Promotes Oxidative Stress and ER Stress, Inhibits STAT3 Activation, and Induces Apoptosis in A549 Lung Adenocarcinoma Cells.
Golgi stress mediates redox imbalance and ferroptosis in human cells.
Knockdown of Trnau1ap inhibits the proliferation and migration of NIH3T3, JEG-3 and Bewo cells via the PI3K/Akt signaling pathway.
Inhibition of NRF2 signaling and increased reactive oxygen species during embryogenesis in a rat model of retinoic acid-induced neural tube defects.
Aberrant expression of redox regulatory proteins in patients with concomitant primary Sclerosing cholangitis/inflammatory bowel disease.
Butaselen prevents hepatocarcinogenesis and progression through inhibiting thioredoxin reductase activity.
Santamarine Inhibits NF-кB and STAT3 Activation and Induces Apoptosis in HepG2 Liver Cancer Cells via Oxidative Stress.
Alantolactone induces apoptosis, promotes STAT3 glutathionylation and enhances chemosensitivity of A549 lung adenocarcinoma cells to doxorubicin via oxidative stress.
The role of sodium hydrosulfide in attenuating the aging process via PI3K/AKT and CaMKKβ/AMPK pathways.
Ruthenium(II) Complexes with 2-Phenylimidazo[4,5-f][1,10]phenanthroline Derivatives that Strongly Combat Cisplatin-Resistant Tumor Cells.
Translational regulation of GPx-1 and GPx-4 by the mTOR pathway.
Altered dietary methionine differentially impacts glutathione and methionine metabolism in long-living growth hormone-deficient Ames dwarf and wild-type mice.
Natural allelic variations in glutathione peroxidase-1 affect its subcellular localization and function.
Upregulation of thioredoxin reductase 1 in human oral squamous cell carcinoma.
Overexpression of thioredoxin system proteins predicts poor prognosis in patients with squamous cell carcinoma of the tongue.
Nucleolin binds to a subset of selenoprotein mRNAs and regulates their expression.
Wang Y, Yuan H, Fang R, Lu J, Duo J, Li G, Wang WJ
Molecular and cellular biochemistry 2024 May 24;
Molecular and cellular biochemistry 2024 May 24;
Development and validation of a disulfidptosis and disulfide metabolism-related risk index for predicting prognosis in lung adenocarcinoma.
Zhong L, Chang W, Luo B, Gao W, He H, Fang M, Li H, Wen Z, Chen Y
Cancer cell international 2024 Jan 2;24(1):2
Cancer cell international 2024 Jan 2;24(1):2
Melatonin antagonizes oxidative stress-induced apoptosis in retinal ganglion cells through activating the thioredoxin-1 pathway.
Gao S, Cheng Q, Hu Y, Fan X, Liang C, Niu C, Kang Q, Wei T
Molecular and cellular biochemistry 2024 Feb 14;
Molecular and cellular biochemistry 2024 Feb 14;
Arginase 2 attenuates ulcerative colitis by antioxidant effects of spermidine.
Imazu N, Torisu T, Yokote A, Umeno J, Kawasaki K, Fujioka S, Matsuno Y, Nagasue T, Kawatoko S, Moriyama T, Nitahata T, Uchida Y, Aihara S, Taniguchi Y, Oda Y, Kitazono T
Journal of gastroenterology 2024 Aug;59(8):682-698
Journal of gastroenterology 2024 Aug;59(8):682-698
Ferroptosis in the colon epithelial cells as a therapeutic target for ulcerative colitis.
Yokote A, Imazu N, Umeno J, Kawasaki K, Fujioka S, Fuyuno Y, Matsuno Y, Moriyama T, Miyawaki K, Akashi K, Kitazono T, Torisu T
Journal of gastroenterology 2023 Sep;58(9):868-882
Journal of gastroenterology 2023 Sep;58(9):868-882
Tremella fuciformis polysaccharides alleviates UV-provoked skin cell damage via regulation of thioredoxin interacting protein and thioredoxin reductase 2.
Lin M, Bao C, Chen L, Geng S, Wang H, Xiao Z, Gong T, Ji C, Cheng B
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 2023 Oct;22(10):2285-2296
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 2023 Oct;22(10):2285-2296
Hypoxia-Induced Changes in L-Cysteine Metabolism and Antioxidative Processes in Melanoma Cells.
Rydz L, Wróbel M, Janik K, Jurkowska H
Biomolecules 2023 Oct 7;13(10)
Biomolecules 2023 Oct 7;13(10)
A prognostic risk model, tumor immune environment modulation, and drug prediction of ferroptosis and amino acid metabolism-related genes in hepatocellular carcinoma.
Ji L, Zhang Q, Cao Y, Liu L
Human cell 2023 May;36(3):1173-1189
Human cell 2023 May;36(3):1173-1189
Nuclear Translocation of LDHA Promotes the Catabolism of BCAAs to Sustain GBM Cell Proliferation through the TxN Antioxidant Pathway.
Li Z, Gu Z, Wang L, Guan Y, Lyu Y, Zhang J, Wang Y, Wang X, Xiong J, Liu Y
International journal of molecular sciences 2023 May 27;24(11)
International journal of molecular sciences 2023 May 27;24(11)
An mRNA processing pathway suppresses metastasis by governing translational control from the nucleus.
Navickas A, Asgharian H, Winkler J, Fish L, Garcia K, Markett D, Dodel M, Culbertson B, Miglani S, Joshi T, Yin K, Nguyen P, Zhang S, Stevers N, Hwang HW, Mardakheh F, Goga A, Goodarzi H
Nature cell biology 2023 Jun;25(6):892-903
Nature cell biology 2023 Jun;25(6):892-903
Discovery of novel hydroxyamidine based indoleamine 2,3-dioxygenase 1 (IDO1) and thioredoxin reductase 1 (TrxR1) dual inhibitors.
Zhou J, Yu LZ, Fan YL, Guo CH, Lv XM, Zhou ZY, Huang HD, Miao DD, Zhang SP, Li XY, Zhao PP, Liu XP, Hu WH, Zhang C
European journal of medicinal chemistry 2023 Jan 5;245(Pt 1):114860
European journal of medicinal chemistry 2023 Jan 5;245(Pt 1):114860
The organic arsenical-derived thioredoxin and glutathione system inhibitor ACZ2 induces apoptosis and autophagy in gastric cancer via ROS-dependent ER stress.
Li Y, She W, Guo T, Huang T, Liu Y, Liu P, Xu X, Wang X, Wang M, Yu C, Liu Y, Wei Y
Biochemical pharmacology 2023 Feb;208:115404
Biochemical pharmacology 2023 Feb;208:115404
TrxR/Trx inhibitor butaselen ameliorates pulmonary fibrosis by suppressing NF-κB/TGF-β1/Smads signaling.
Chen Y, Yin H, Sun J, Zhang G, Zhang Y, Zeng H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec 31;169:115822
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec 31;169:115822
Seven oxidative stress-related genes predict the prognosis of hepatocellular carcinoma.
Miao C, He X, Chen G, Kahlert UD, Yao C, Shi W, Su D, Hu L, Zhang Z
Aging 2023 Dec 14;15(24):15050-15063
Aging 2023 Dec 14;15(24):15050-15063
Elovanoid-N34 modulates TXNRD1 key in protection against oxidative stress-related diseases.
Calandria JM, Bhattacharjee S, Kala-Bhattacharjee S, Mukherjee PK, Feng Y, Vowinckel J, Treiber T, Bazan NG
Cell death & disease 2023 Dec 13;14(12):819
Cell death & disease 2023 Dec 13;14(12):819
SERD-NHC-Au(I) complexes for dual targeting ER and TrxR to induce ICD in breast cancer.
Lu Y, Sheng X, Liu C, Liang Z, Wang X, Liu L, Wen Z, Yang Z, Du Q, Liu W
Pharmacological research 2023 Apr;190:106731
Pharmacological research 2023 Apr;190:106731
Metabolism-Related Gene TXNRD1 Regulates Inflammation and Oxidative Stress Induced by Cigarette Smoke through the Nrf2/HO-1 Pathway in the Small Airway Epithelium.
Huang Q, Peng M, Gu Y, Wu J, Zhan Y, Deng Z, Chen S, Yang R, Chen J, Xie J
Oxidative medicine and cellular longevity 2022;2022:7067623
Oxidative medicine and cellular longevity 2022;2022:7067623
Fast regulation of the NF-κB signalling pathway in human skeletal muscle revealed by high-intensity exercise and ischaemia at exhaustion: Role of oxygenation and metabolite accumulation.
Gallego-Selles A, Galvan-Alvarez V, Martinez-Canton M, Garcia-Gonzalez E, Morales-Alamo D, Santana A, Gonzalez-Henriquez JJ, Dorado C, Calbet JAL, Martin-Rincon M
Redox biology 2022 Sep;55:102398
Redox biology 2022 Sep;55:102398
Selenium Deficiency Leads to Changes in Renal Fibrosis Marker Proteins and Wnt/β-Catenin Signaling Pathway Components.
Lin T, Tao J, Chen Y, Zhang Y, Li F, Zhang Y, Han X, Zhao Z, Liu G, Li H
Biological trace element research 2022 Mar;200(3):1127-1139
Biological trace element research 2022 Mar;200(3):1127-1139
Nanoparticle delivery of miR-21-3p sensitizes melanoma to anti-PD-1 immunotherapy by promoting ferroptosis.
Guo W, Wu Z, Chen J, Guo S, You W, Wang S, Ma J, Wang H, Wang X, Wang H, Ma J, Yang Y, Tian Y, Shi Q, Gao T, Yi X, Li C
Journal for immunotherapy of cancer 2022 Jun;10(6)
Journal for immunotherapy of cancer 2022 Jun;10(6)
Anti-Inflammatory Effect of Dimethyl Fumarate Associates with the Inhibition of Thioredoxin Reductase 1 in RAW 264.7 Cells.
Yang R, Sun S, Guo Y, Meng Y, Liu H, Shi M, Guan S, Xu J
Molecules (Basel, Switzerland) 2022 Dec 23;28(1)
Molecules (Basel, Switzerland) 2022 Dec 23;28(1)
The role of selenoproteins in neutrophils during inflammation.
Lee TJ, Nettleford SK, McGlynn A, Carlson BA, Kirimanjeswara GS, Prabhu KS
Archives of biochemistry and biophysics 2022 Dec 15;732:109452
Archives of biochemistry and biophysics 2022 Dec 15;732:109452
Menadione Potentiates Auranofin-Induced Glioblastoma Cell Death.
Szeliga M, Rola R
International journal of molecular sciences 2022 Dec 11;23(24)
International journal of molecular sciences 2022 Dec 11;23(24)
Therapeutic Effects of an Inhibitor of Thioredoxin Reductase on Liver Fibrosis by Inhibiting the Transforming Growth Factor-β1/Smads Pathway.
Jiao W, Bai M, Yin H, Liu J, Sun J, Su X, Zeng H, Wen J
Frontiers in molecular biosciences 2021;8:690170
Frontiers in molecular biosciences 2021;8:690170
Helenalin Facilitates Reactive Oxygen Species-Mediated Apoptosis and Cell Cycle Arrest by Targeting Thioredoxin Reductase-1 in Human Prostate Cancer Cells.
Yang M, Zhang W, Yu X, Wang F, Li Y, Zhang Y, Yang Y
Medical science monitor : international medical journal of experimental and clinical research 2021 Jun 14;27:e930083
Medical science monitor : international medical journal of experimental and clinical research 2021 Jun 14;27:e930083
Mechanistic Analysis of an Extracellular Signal-Regulated Kinase 2-Interacting Compound that Inhibits Mutant BRAF-Expressing Melanoma Cells by Inducing Oxidative Stress.
Martinez R 3rd, Huang W, Samadani R, Mackowiak B, Centola G, Chen L, Conlon IL, Hom K, Kane MA, Fletcher S, Shapiro P
The Journal of pharmacology and experimental therapeutics 2021 Jan;376(1):84-97
The Journal of pharmacology and experimental therapeutics 2021 Jan;376(1):84-97
Libertellenone H, a Natural Pimarane Diterpenoid, Inhibits Thioredoxin System and Induces ROS-Mediated Apoptosis in Human Pancreatic Cancer Cells.
Zhang W, Zhu Y, Yu H, Liu X, Jiao B, Lu X
Molecules (Basel, Switzerland) 2021 Jan 9;26(2)
Molecules (Basel, Switzerland) 2021 Jan 9;26(2)
Discovery of hydroxytyrosol as thioredoxin reductase 1 inhibitor to induce apoptosis and G(1)/S cell cycle arrest in human colorectal cancer cells via ROS generation.
Zhang SP, Zhou J, Fan QZ, Lv XM, Wang T, Wang F, Chen Y, Hong SY, Liu XP, Xu BS, Hu L, Zhang C, Zhang YM
Experimental and therapeutic medicine 2021 Aug;22(2):829
Experimental and therapeutic medicine 2021 Aug;22(2):829
Fasting Induces Hepatocellular Carcinoma Cell Apoptosis by Inhibiting SET8 Expression.
Qi J, Chen X, Wu Q, Wang J, Zhang H, Mao A, Zhu M, Miao C
Oxidative medicine and cellular longevity 2020;2020:3985089
Oxidative medicine and cellular longevity 2020;2020:3985089
WHSC1 Promotes Cell Proliferation, Migration, and Invasion in Hepatocellular Carcinoma by Activating mTORC1 Signaling.
Dai J, Jiang L, Qiu L, Shao Y, Shi P, Li J
OncoTargets and therapy 2020;13:7033-7044
OncoTargets and therapy 2020;13:7033-7044
Synthesis and biological evaluation of gold(III) Schiff base complexes for the treatment of hepatocellular carcinoma through attenuating TrxR activity.
Bian M, Wang X, Sun Y, Liu W
European journal of medicinal chemistry 2020 May 1;193:112234
European journal of medicinal chemistry 2020 May 1;193:112234
Synthesis and biological evaluation of myricetin-pentadienone hybrids as potential anti-inflammatory agents in vitro and in vivo.
Liu C, Han X, Yu PJ, Chen LZ, Xue W, Liu XH
Bioorganic chemistry 2020 Mar;96:103597
Bioorganic chemistry 2020 Mar;96:103597
A Gold(I) Complex Containing an Oleanolic Acid Derivative as a Potential Anti-Ovarian-Cancer Agent by Inhibiting TrxR and Activating ROS-Mediated ERS.
Bian M, Sun Y, Liu Y, Xu Z, Fan R, Liu Z, Liu W
Chemistry (Weinheim an der Bergstrasse, Germany) 2020 Jun 2;26(31):7092-7108
Chemistry (Weinheim an der Bergstrasse, Germany) 2020 Jun 2;26(31):7092-7108
Targeting the MAPK/ERK and PI3K/AKT Signaling Pathways Affects NRF2, Trx and GSH Antioxidant Systems in Leukemia Cells.
Jasek-Gajda E, Jurkowska H, Jasińska M, Lis GJ
Antioxidants (Basel, Switzerland) 2020 Jul 17;9(7)
Antioxidants (Basel, Switzerland) 2020 Jul 17;9(7)
The novel thioredoxin reductase inhibitor A-Z2 triggers intrinsic apoptosis and shows efficacy in the treatment of acute myeloid leukemia.
Zhang D, Liu Y, Luo Z, Chen Y, Xu A, Liang Y, Wu B, Tong X, Liu X, Shen H, Liu L, Wei Y, Zhou H, Liu Y, Zhou F
Free radical biology & medicine 2020 Jan;146:275-286
Free radical biology & medicine 2020 Jan;146:275-286
Design, synthesis, and biological evaluation of a novel indoleamine 2,3-dioxigenase 1 (IDO1) and thioredoxin reductase (TrxR) dual inhibitor.
Fan QZ, Zhou J, Zhu YB, He LJ, Miao DD, Zhang SP, Liu XP, Zhang C
Bioorganic chemistry 2020 Dec;105:104401
Bioorganic chemistry 2020 Dec;105:104401
miR-125b-5p inhibits cell proliferation, migration, and invasion in hepatocellular carcinoma via targeting TXNRD1.
Hua S, Quan Y, Zhan M, Liao H, Li Y, Lu L
Cancer cell international 2019;19:203
Cancer cell international 2019;19:203
Effects of KEAP1 Silencing on the Regulation of NRF2 Activity in Neuroendocrine Lung Tumors.
Sparaneo A, Fabrizio FP, la Torre A, Graziano P, Di Maio M, Fontana A, Bisceglia M, Rossi A, Pizzolitto S, De Maglio G, Tancredi A, Grimaldi F, Balsamo T, Centra F, Manzorra MC, Trombetta D, Pantalone A, Bonfitto A, Maiello E, Fazio VM, Muscarella LA
International journal of molecular sciences 2019 May 23;20(10)
International journal of molecular sciences 2019 May 23;20(10)
A novel iron(II) phenanthroline complex exhibits anticancer activity against TFR1-overexpressing esophageal squamous cell carcinoma cells through ROS accumulation and DNA damage.
Ye J, Ma J, Liu C, Huang J, Wang L, Zhong X
Biochemical pharmacology 2019 Aug;166:93-107
Biochemical pharmacology 2019 Aug;166:93-107
Proscillaridin A Promotes Oxidative Stress and ER Stress, Inhibits STAT3 Activation, and Induces Apoptosis in A549 Lung Adenocarcinoma Cells.
Maryam A, Mehmood T, Yan Q, Li Y, Khan M, Ma T
Oxidative medicine and cellular longevity 2018;2018:3853409
Oxidative medicine and cellular longevity 2018;2018:3853409
Golgi stress mediates redox imbalance and ferroptosis in human cells.
Alborzinia H, Ignashkova TI, Dejure FR, Gendarme M, Theobald J, Wölfl S, Lindemann RK, Reiling JH
Communications biology 2018;1:210
Communications biology 2018;1:210
Knockdown of Trnau1ap inhibits the proliferation and migration of NIH3T3, JEG-3 and Bewo cells via the PI3K/Akt signaling pathway.
Hu X, Luo J, Lai H, Li M, Zheng X, Nie T, Li F, Li H
Biochemical and biophysical research communications 2018 Sep 5;503(2):521-527
Biochemical and biophysical research communications 2018 Sep 5;503(2):521-527
Inhibition of NRF2 signaling and increased reactive oxygen species during embryogenesis in a rat model of retinoic acid-induced neural tube defects.
Liu D, Xue J, Liu Y, Gu H, Wei X, Ma W, Luo W, Ma L, Jia S, Dong N, Huang J, Wang Y, Yuan Z
Neurotoxicology 2018 Dec;69:84-92
Neurotoxicology 2018 Dec;69:84-92
Aberrant expression of redox regulatory proteins in patients with concomitant primary Sclerosing cholangitis/inflammatory bowel disease.
Petersen DR, Orlicky DJ, Roede JR, Shearn CT
Experimental and molecular pathology 2018 Aug;105(1):32-36
Experimental and molecular pathology 2018 Aug;105(1):32-36
Butaselen prevents hepatocarcinogenesis and progression through inhibiting thioredoxin reductase activity.
Zheng X, Ma W, Sun R, Yin H, Lin F, Liu Y, Xu W, Zeng H
Redox biology 2018 Apr;14:237-249
Redox biology 2018 Apr;14:237-249
Santamarine Inhibits NF-кB and STAT3 Activation and Induces Apoptosis in HepG2 Liver Cancer Cells via Oxidative Stress.
Mehmood T, Maryam A, Tian X, Khan M, Ma T
Journal of Cancer 2017;8(18):3707-3717
Journal of Cancer 2017;8(18):3707-3717
Alantolactone induces apoptosis, promotes STAT3 glutathionylation and enhances chemosensitivity of A549 lung adenocarcinoma cells to doxorubicin via oxidative stress.
Maryam A, Mehmood T, Zhang H, Li Y, Khan M, Ma T
Scientific reports 2017 Jul 24;7(1):6242
Scientific reports 2017 Jul 24;7(1):6242
The role of sodium hydrosulfide in attenuating the aging process via PI3K/AKT and CaMKKβ/AMPK pathways.
Chen X, Zhao X, Cai H, Sun H, Hu Y, Huang X, Kong W, Kong W
Redox biology 2017 Aug;12:987-1003
Redox biology 2017 Aug;12:987-1003
Ruthenium(II) Complexes with 2-Phenylimidazo[4,5-f][1,10]phenanthroline Derivatives that Strongly Combat Cisplatin-Resistant Tumor Cells.
Zeng L, Chen Y, Liu J, Huang H, Guan R, Ji L, Chao H
Scientific reports 2016 Jan 14;6:19449
Scientific reports 2016 Jan 14;6:19449
Translational regulation of GPx-1 and GPx-4 by the mTOR pathway.
Reinke EN, Ekoue DN, Bera S, Mahmud N, Diamond AM
PloS one 2014;9(4):e93472
PloS one 2014;9(4):e93472
Altered dietary methionine differentially impacts glutathione and methionine metabolism in long-living growth hormone-deficient Ames dwarf and wild-type mice.
Brown-Borg HM, Rakoczy S, Wonderlich JA, Armstrong V, Rojanathammanee L
Longevity & healthspan 2014;3(1):10
Longevity & healthspan 2014;3(1):10
Natural allelic variations in glutathione peroxidase-1 affect its subcellular localization and function.
Bera S, Weinberg F, Ekoue DN, Ansenberger-Fricano K, Mao M, Bonini MG, Diamond AM
Cancer research 2014 Sep 15;74(18):5118-26
Cancer research 2014 Sep 15;74(18):5118-26
Upregulation of thioredoxin reductase 1 in human oral squamous cell carcinoma.
Iwasawa S, Yamano Y, Takiguchi Y, Tanzawa H, Tatsumi K, Uzawa K
Oncology reports 2011 Mar;25(3):637-44
Oncology reports 2011 Mar;25(3):637-44
Overexpression of thioredoxin system proteins predicts poor prognosis in patients with squamous cell carcinoma of the tongue.
Zhu X, Huang C, Peng B
Oral oncology 2011 Jul;47(7):609-14
Oral oncology 2011 Jul;47(7):609-14
Nucleolin binds to a subset of selenoprotein mRNAs and regulates their expression.
Miniard AC, Middleton LM, Budiman ME, Gerber CA, Driscoll DM
Nucleic acids research 2010 Aug;38(14):4807-20
Nucleic acids research 2010 Aug;38(14):4807-20
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Jurkat cells were subjected to SDS PAGE followed by western blot with 11117-1-AP(TXNRD1 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of MCF-7 cells, using TXNRD1 antibody 11117-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-TXNRD1 (IP:11117-1-AP, 3ug; Detection:11117-1-AP 1:500) with Jurkat cells lysate 1500ug.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human breast cancer using 11117-1-AP(TXNRD1 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue