AP0353

antibody from Bioworld Technology, Inc
Targeting: VDR NR1I1, PPP1R163
Provider product page for AP0353

Antibody data

Product number
AP0353 - Provider product page
Provider
Bioworld Technology, Inc
Product name
VDR (phospho S208) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic phosphopeptide derived from human VDR around the phosphorylation site of Serine 208.
Description
The vitamin D receptor (VDR), also known as the calcitriol receptor, and also known as NR1I1 (nuclear receptor subfamily 1, group I, member 1), is a member of the nuclear receptor family of transcription factors. Upon activation by vitamin D, the VDR forms a heterodimer with the retinoid-X receptor and binds to hormone response elements on DNA resulting in expression or trans-repression of specific gene products.It is an intracellular hormone receptor that specifically binds 1,25(OH)2D3 and mediates its effects. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer.
Reactivity
Human, Mouse
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
VDR protein structure - AP0353 shown in red.