VDR

gene product
NR1I1, PPP1R163
This gene encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding different proteins. [provided by RefSeq, Feb 2011]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

  or   Clear
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Validated within AVI
Eligible for validation within AVI
725 antibodies from 39 providers.

Antibody properties

General

Applications

or Cancel
AntibodyRefsTypeWBELICCIPIHCFC
Invitrogen Antibodies
9 antibodies
Novus Biologicals
8 antibodies
R&D Systems
1 antibody
Santa Cruz Biotechnology
1 antibody
antibodies-online
216 antibodies
Acris Antibodies GmbH
12 antibodies
Enzo Life Sciences
1 antibody
Aviva Systems Biology
14 antibodies
Biorbyt
33 antibodies
GeneTex
10 antibodies
Affinity Biosciences
3 antibodies
LifeSpan BioSciences, Inc.
162 antibodies
NovoPro Bioscience Inc.
9 antibodies
Abnova Corporation
9 antibodies
Cell Signaling Technology, Inc
1 antibody
Bioworld Technology, Inc
4 antibodies
St John's Laboratory
8 antibodies
OriGene
18 antibodies
NSJ Bioreagents
6 antibodies
Abgent
10 antibodies
Arigo
3 antibodies
Abbkine Scientific Co.Ltd.
4 antibodies
Creative Diagnostics
8 antibodies
Boster Biological Technology
3 antibodies
Antibodies.com
1 antibody
Everest Biotech
1 antibody
Creative Biolabs
17 antibodies
ProSci
6 antibodies
RabMAbs
3 antibodies
RayBiotech, Inc.
4 antibodies
Atlas Antibodies
1 antibody
Proteintech Group
1 antibody
United States Biological
104 antibodies
MyBioSource
13 antibodies
Bethyl Laboratories
2 antibodies
EMD Millipore
1 antibody
Sigma-Aldrich
4 antibodies
GenWay
2 antibodies