Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations [0]
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- Product number
- ABIN358251 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-WEE1 Homolog (S. Pombe) (WEE1) (pSer123) antibody
- Antibody type
- Polyclonal
- Description
- Protein G Affinity Chromatography. Then, the antibody fraction is peptide affinity purified in a 2-step procedure with control and phosphorylated peptides. The phospho-specific antibody is eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- pSer123
- Vial size
- 0.4 mL
- Storage
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references M-phase kinases induce phospho-dependent ubiquitination of somatic Wee1 by SCFbeta-TrCP.
Keratinocyte G2/M growth arrest by 1,25-dihydroxyvitamin D3 is caused by Cdc2 phosphorylation through Wee1 and Myt1 regulation.
The clinical significance of Cyclin B1 and Wee1 expression in non-small-cell lung cancer.
Human wee1 kinase is directly transactivated by and increased in association with c-Fos/AP-1: rheumatoid synovial cells overexpressing these genes go into aberrant mitosis.
Depletion of Wee-1 kinase is necessary for both human immunodeficiency virus type 1 Vpr- and gamma irradiation-induced apoptosis.
Watanabe N, Arai H, Nishihara Y, Taniguchi M, Watanabe N, Hunter T, Osada H
Proceedings of the National Academy of Sciences of the United States of America 2004 Mar 30;101(13):4419-24
Proceedings of the National Academy of Sciences of the United States of America 2004 Mar 30;101(13):4419-24
Keratinocyte G2/M growth arrest by 1,25-dihydroxyvitamin D3 is caused by Cdc2 phosphorylation through Wee1 and Myt1 regulation.
Dai X, Yamasaki K, Yang L, Sayama K, Shirakata Y, Tokumara S, Yahata Y, Tohyama M, Hashimoto K
The Journal of investigative dermatology 2004 Jun;122(6):1356-64
The Journal of investigative dermatology 2004 Jun;122(6):1356-64
The clinical significance of Cyclin B1 and Wee1 expression in non-small-cell lung cancer.
Yoshida T, Tanaka S, Mogi A, Shitara Y, Kuwano H
Annals of oncology : official journal of the European Society for Medical Oncology 2004 Feb;15(2):252-6
Annals of oncology : official journal of the European Society for Medical Oncology 2004 Feb;15(2):252-6
Human wee1 kinase is directly transactivated by and increased in association with c-Fos/AP-1: rheumatoid synovial cells overexpressing these genes go into aberrant mitosis.
Kawasaki H, Komai K, Nakamura M, Yamamoto E, Ouyang Z, Nakashima T, Morisawa T, Hashiramoto A, Shiozawa K, Ishikawa H, Kurosaka M, Shiozawa S
Oncogene 2003 Oct 9;22(44):6839-44
Oncogene 2003 Oct 9;22(44):6839-44
Depletion of Wee-1 kinase is necessary for both human immunodeficiency virus type 1 Vpr- and gamma irradiation-induced apoptosis.
Yuan H, Xie YM, Chen IS
Journal of virology 2003 Feb;77(3):2063-70
Journal of virology 2003 Feb;77(3):2063-70
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