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- Antibody Data
- Antigen structure
- References [863]
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- Western blot [1]
- Immunocytochemistry [1]
- Immunoprecipitation [1]
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- Product number
- 11587-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11587-1-AP, RRID:AB_2119855
- Product name
- GRP78/BIP antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated GRP78/BIP antibody (Cat. #11587-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Hsph1 alleviates hypoxia-glucose deprivation-induced cardiomyocyte damage by regulating endoplasmic reticulum stress.
After Traumatic Brain Injury, EPHA4 Enhances Endoplasmic Reticulum Stress to Promote M1 Microglial Polarization Through the MAPK Signaling Pathway.
Electroacupuncture reduces calcium influx and inhibits endoplasmic reticulum stress by inhibiting the PKCδ-TRPA1 pathway to promote motor function recovery after spinal cord injury.
RNF26 regulating tumor immunogenicity of hepatocellular carcinoma by degrading GRP78 and instigating ER stress.
Nur77 attenuates Paneth cell necroptosis-induced intestinal inflammation through regulating endoplasmic reticulum homeostasis in sepsis.
PRAS40 activates the IRE1α-XBP-1-mediated unfolded protein response to exacerbate colorectal cancer by enhancing ST6Gal1-dependent α-2, 6 sialylation of GRP78.
ATF3 links endoplasmic reticulum stress to ferroptosis via transcriptional activation of ALOX12 in benzene-induced hematotoxicity.
SIRT3 promotes oxaliplatin sensitivity in hepatocellular carcinoma by promoting ferroptosis through endoplasmic reticulum stress response.
Increased FICD-mediated protein AMPylation triggers conserved endoplasmic reticulum stress signaling across species.
The sphingolipid metabolite sphingosine protects against hypertension by targeting metabolic-inflammatory crosstalk via the NLRP3 inflammasome.
ENDOU-1-induced cytoplasmic HnRNPA3 recognizes m6A methylation on the upstream reading frame of human CHOP transcripts to achieve maximal CHOP translation.
Investigating PKD2 deficiency-associated cardiomyopathies using hESC-cardiomyocytes and bioengineered 3D ventricular cardiac tissue strips.
Ferulic Acid Alleviates Chemotherapy-Induced POI by Targeting the Grp78 and Perk-eIF2α-ATF4-CHOP Pathway to Attenuate Endoplasmic Reticulum Stress.
Modulating GRP75 to restore calcium homeostasis: a novel neuroprotective strategy of CRSE6(#) in Parkinson's disease models.
LCN2 aggravates sepsis-induced ALI by inhibiting MUC1 to activate ER-stress-autophagy induced ferroptosis via lactate/MCT1/AMPK/mTOR axis.
African swine fever virus MGF_110-8L promotes host cell autophagy and suppresses interferon signaling by activating the unfolded protein response.
Truncated N-glycans destabilize POMT1 and POMT2 but do not limit cellular O-mannosylation in HEK293 cells.
Leveraging ANXA1 to enhance recombinant protein yields in CHO cells: A UPR-Mediated bioprocessing approach.
Tetramethylpyrazine mitigates ER-stress-driven ATF4/CHOP apoptosis to protect dopaminergic neurons in cellular and MPTP models of Parkinson's disease.
CAMKMT knockdown delays myopia progression by reducing calcium Ion-mediated ER Stress-induced apoptosis.
PDIA6 as a novel pharmacological target for metabolic dysfunction-associated steatohepatitis via alleviating endoplasmic reticulum stress.
Single-cell transcriptomic atlas of shrimp hepatopancreas reveals an endoplasmic reticulum stress-dependent immune response to Vibrio parahaemolyticus infection.
The lamin A/C-P4HB interaction axis regulates endoplasmic reticulum stress and apoptosis in myocardial ischemia-reperfusion injury via a calreticulin-associated mechanism.
LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells.
Sennoside A ameliorates cognitive impairment by inhibiting USP14/ERK1/2 pathway in a mouse model of type 2 diabetes mellitus.
SRSF3 promotes the generation of XBP1s to stabilize autophagy and enhance hypoxia adaptation in glioma.
Differential Toxicity of Water-Soluble Versus Water-Insoluble Components of Cowshed PM2.5 on Ovarian Granulosa Cells and the Regulatory Role of Txnip in Overall Toxicity.
Ginseng Polysaccharides Protect Against Endoplasmic Reticulum Stress-Induced Damage via PI3K/Akt Signalling Pathway in Bovine Ovarian Granulosa Cells.
Quantitative proteomic analysis identifies the unfolded protein response as a host pathway co-opted by ASFV to promote replication.
Detection of factors related to ROS and ERS in the reproductive organs of hibernating Daurian ground squirrels (Spermophilus dauricus)†.
AhR/ROS-mediated endoplasmic reticulum stress contributes to PFOSA-induced cardiac defects.
GNB2 promotes breast cancer progression by up-regulating HSPA5/GPX4 and inhibiting ferroptosis.
Helicobacter mastomyrinus Cytolethal Distending Toxin Induces Calcium Dyshomeostasis and Liver Injury via Endoplasmic Reticulum Stress.
HSPA5 promotes YAP/TAZ stability independently of the Hippo pathway and induces proneural-to-mesenchymal transition in glioblastoma.
Mazdutide Ameliorates Metabolic Dysfunction-Associated Steatotic Liver Disease by Modulating Endoplasmic Reticulum Stress, Improving Lipid Metabolism and Alleviating Inflammation.
Inhibiting HSP27 activates the XBP1s/CerS1 interplay, which triggers DRP1-driven mitophagy, thereby protecting against cell death and promoting the KSHV lytic cycle in primary effusion lymphoma cells.
NEAT1 drives SARS-CoV-2 N protein-induced inflammation, metabolic reprogramming, and mitochondria-ER stress crosstalk.
Role of Sigma-1 Receptors in the Paraventricular Nucleus and Myocardium during Cirrhotic Cardiomyopathy in Rats.
VAMP7-dependent late endosomal secretion of ER and mitochondrial proteins impacts the tumor microenvironment and macrophage engagement.
LncRNA SLC16A1-AS1 cooperates with NSUN2 to stabilize GRP78 mRNA via m5C modification in gastric cancer.
TAZ (Wwtr1) deficiency leads to ER stress and mitochondrial dysfunction in a mouse model of Fuchs' endothelial corneal dystrophy.
CLCC1 governs ER bilayer equilibration to maintain lipid homeostasis.
Brucella Omp25 activates the unfolded protein response to promote intracellular proliferation and inflammation.
Tetrastigma Hemsleyanum Polysaccharide Suppresses Triple-Negative Breast Cancer by Disrupting the Hippo-YAP/TEAD4-PDIA4 Axis and Endoplasmic Reticulum Stress Adaptation.
Advanced oxidation protein products exacerbate osteoarthritis progression by disrupting stress granules assembly via endoplasmic reticulum stress.
Cardiac and brain pathological alterations with potential biomarker screening in stress-related fatalities.
Qizhi Kebitong Formula Ameliorates Sciatic Nerve Injury in Streptozocin-induced Diabetic Mice through PERK/ATF4/CHOP Endoplasmic Reticulum Stress Signaling Pathway.
Decoding Endoplasmic Reticulum Stress on Chondrocyte Driving Osteoarthritis Development through Integrating Single-Cell and Transcriptomic Profiling.
FKBP10 Promotes the Muscle Invasion of Bladder Cancer via Lamin A Dysregulation.
The lncRNA SENCR knockdown alleviates vascular calcification via miR-4731-5p by suppressing endoplasmic reticulum stress.
Thyroid Stimulating Hormone May Facilitates Adipose Tissue Insulin Resistance by Inducing M1 Macrophage Polarization.
Huanglian Jiedu Decoction Alleviates Myocardial Ischemia-Reperfusion Injury via AKT-Mediated Regulation of Endoplasmic Reticulum Stress.
Volatile Oil From Acorus Gramineus Rhizoma Synergizes with Crebanine to Alleviate Oxidative Stress and Endoplasmic Reticulum Stress in Myocardial Ischemia-Reperfusion Injury by Suppressing GRP78-PERK/ATF6-CHOP and MAPK-NF-κB-TNF-α Signaling Pathways.
Liangfang Wenjing decoction regulates endoplasmic reticulum stress-mediated apoptosis to alleviate uterine microvascular injury in cold-stressed rats.
Targeting the self-amplifying loop between ATF6 and SNAI1 to inhibit epithelial‒mesenchymal transition in fibrotic lesions.
Screening and identification of protein interacting with goose astrovirus.
Impaired stemness in aging periodontal ligament stem cells is mediated by the progerin/endoplasmic reticulum stress/p53 axis.
Dimethyloxalylglycine improves functional recovery through inhibiting cell apoptosis and enhancing blood-spinal cord barrier repair after spinal cord injury.
Quercetin diminishes scleral ER stress and protein misfolding: High throughput transcriptome analysis in form-deprivation myopia of Guinea pigs.
Zinc Transporter 9 (ZnT9) Improves Obesity-Induced Asthenospermia by Attenuating Endoplasmic Reticulum Stress (ERS).
hsa_circ_0004771-Targeted Adsorption of miR-429 Mediates ATP2A2 Expression to Attenuate Endoplasmic Reticulum Stress and Mitochondrial Dysfunction During Myocardial Infarction.
Catestatin attenuates cerebral ischemia/reperfusion injury and suppresses endoplasmic reticulum stress.
Propylparaben disrupts early embryonic development by causing oxidative stress-induced organelle dysfunction and actin zipper abnormality.
PMAIP1 mediates endoplasmic reticulum stress in human dental pulp stem cells during pulpitis pathogenesis.
Mechanistic insights into fluoride-induced reproductive toxicity in female ovine animals: Mitochondrial dysfunction and ER stress-driven apoptosis in ovine granulosa cells.
Nickel exposure induced endoplasmic reticulum stress by disturbing calcium homeostasis and triggered mitochondrial autophagy in domestic animal oocytes.
Protective role of RGS2 in PM2.5-induced ovarian injury in rats: Modulation of Gq/11 signaling to maintain granulosa cell [Ca(2 +) ]i stability.
Investigation of the effects of umbilical cord and adipose-derived mesenchymal stem cells on endoplasmic reticulum stress in cadmium-induced rat kidney.
cZFP609 Tethering BiP Alleviates Cartilage Degradation in Osteoarthritis via Remedying Aberrant ER-Mitochondrial Contacts.
Baicalin inhibits LPS-induced apoptosis and inflammation in WI- 38 cells by promoting FOXA2/TRIM27 Interaction: Implications for pediatric pneumonia mechanisms.
Quercetin induces immunogenic cell death against gastric cancer by targeting NR3C1.
Perfluorohexane sulfonate (PFHxS) induces liver cytotoxicity by activating autophagy and endoplasmic reticulum stress-regulated mitochondrial pathway apoptosis.
Activation of Lysosomal Retrograde Transport Triggers TPC1-IP3R1 Ca(2+) Crosstalk at Lysosome-ER MCSs Leading to Lethal Depleting of ER Calcium.
Intestinal Epithelial-Derived USP13 Alleviates Colonic Inflammation by Suppressing GRP78-mediated Endoplasmic Reticulum Stress.
Legionella pneumophila Effector Protein LegU1 Mediates the Ubiquitination of Endoplasmic Reticulum Chaperone BiP.
Endoplasmic reticulum-resident protein DNAJC10 inhibits glioblastoma metastasis by suppressing XBP-1s-driven EGFR transcription.
DNAJC5 promotes cisplatin resistance in epithelial ovarian cancer by autophagy induced by the BiP/IRE1α/XBP1 endoplasmic reticulum stress pathway.
Changes of N(6)-methyladenosine modification and unfolded protein response in renal cell injury induced by cadmium.
Tumor-resident probiotic Clostridium butyricum improves aPD-1 efficacy in colorectal cancer models by inhibiting IL-6-mediated immunosuppression.
Malate targets pyruvate kinase M2 to promote colorectal cancer cell cycle arrest and tumor suppression.
Hypericin photoactivation induces triple-negative breast cancer cells pyroptosis by targeting the ROS/CALR/Caspase-3/GSDME pathway.
Aerobic Exercise Training Exerts Neuroprotective Effects in Alzheimer's Disease Mice by Regulating Endoplasmic Reticulum Stress-Autophagy Pathway-Mediated Pyroptosis.
Astragalin induces immunogenic cell death in liver cancer by targeting NQO2 to promote ROS-mediated endoplasmic reticulum stress pathway.
Hydrogen sulfide alleviates vascular smooth muscle cell senescence by inhibiting endoplasmic reticulum stress.
Regulatory role of sirtuin-1 by targeting MDM2 to mitochondria-associated membranes formation in the treatment of NAFLD.
RNF186 controls glucose metabolism in metabolic dysfunction-associated fatty liver disease.
Thymoquinone inhibited the chondrogenic differentiation of tendon-derived stem cells caused by tendon injury.
Sec14L6 is a phosphoinositide transporter that regulates phosphoinositide homeostasis and biogenesis of lipid droplets.
ER protein CLCC1 promotes nuclear envelope fusion in herpesviral and host processes.
Crucial roles of GALNT6-mediated O-glycosylation of GRP78/Bip in proliferation of breast cancer cells.
Quercetin alleviated cadmium-induced oxidative stress, endoplasmic reticulum stress, and autophagy in chicken kidneys.
SIRT1 Alleviates Oxidative Stress-Induced Mitochondrial Dysfunction and Mitochondria-Associated Membrane Dysregulation in Stress Urinary Incontinence.
Simulated microgravity activates autophagy expression in the rat retina.
The selenocysteine-containing protein SELENOT maintains dopamine signaling in the midbrain to protect mice from hyperactivity disorder.
FAM134B-mediated ER-phagy alleviates alcohol-related liver fibrosis by reducing endoplasmic reticulum stress.
SIRT5 modulates mitochondria function via mitophagy and antioxidant mechanisms to facilitate oocyte maturation in mice.
Grafting of syringic acid onto fucoidan: Enhanced functional properties and therapeutic potential in histamine-induced liver injury.
Discovery of a potent inhibitor of chaperone-mediated autophagy that targets the HSC70-LAMP2A interaction in non-small cell lung cancer cells.
USP51/GRP78/ABCB1 axis confers chemoresistance through decreasing doxorubicin accumulation in triple-negative breast cancer cells.
GRP78 Nanobody-Directed Immunotoxin Activates Innate Immunity Through STING Pathway to Synergize Tumor Immunotherapy.
USP18 attenuates endoplasmic reticulum stress via the PERK-eIF2α-ATF4 axis to reduce apoptosis in hepatocellular carcinoma cells.
Endoplasmic Reticulum Stress Inhibition Promotes Mitophagy via Miro1 Reduction to Rescue Mitochondrial Dysfunction and Protect Dopamine Neurons in Parkinson's Disease.
Potential mechanisms by which Jiawei Lianpu Yin inhibits Helicobacter pylori colonization and alleviates gastric mucosal inflammation and damage: Integrated transcriptomics, network pharmacology, and experimental validation.
Lipid droplet accumulation impairs osseointegration by disturbing the osteogenesis-osteoclasis balance on titanium implant surface in hyperlipidemia.
TRx0237 induces apoptosis and enhances anti-PD-1 immunotherapeutic efficacy in anaplastic thyroid Cancer.
Aldehyde dehydrogenase 2 attenuates renal injury through inhibiting CYP4A expression.
Aerobic exercise improves energy and glucose homeostasis through hypothalamic Mitofusion 2-rescued endoplasmic reticulum stress in diet-induced obese mice.
Age‑related changes in endoplasmic reticulum stress response‑associated protein expression in rat tibial nerves.
Boric Acid Alleviates Lipopolysaccharide-Induced Acute Lung Injury in Mice.
Andrographolide ameliorates sepsis-induced acute liver injury by attenuating endoplasmic reticulum stress through the FKBP1A-mediated NOTCH1/AK2 pathway.
Clemastine fumarate alleviates endoplasmic reticulum stress through the Nur77/GFPT2/CHOP pathway after ischemia/reperfusion in rat hearts.
Citrinin-Induced Intestinal Onset of Pyroptosis via the IP3R1-GRP75-VDAC1 Complex-Mediated Mitochondrial Oxidative Stress.
Triclosan Caused Oocyte Meiotic Arrest by Modulating Oxidative Stress, Organelle Dysfunctions, Autophagy, and Apoptosis in Pigs.
Exogenous hydrogen sulfide improves non-alcoholic fatty liver disease by inhibiting endoplasmic reticulum stress/NLRP3 inflammasome pathway.
Endoplasmic Reticulum Stress and NLRP3 Inflammasome Activation Underlie Silver Nanoparticles-Induced Neurologic Deficits in Adult Mice.
Quercetin-loaded exosomes delivery system prevents myopia progression by targeting endoplasmic reticulum stress and ferroptosis in scleral fibroblasts.
Polygonatum cyrtonema polysaccharide alleviates dopaminergic neuron apoptosis in Parkinson's disease mouse model via inhibiting oxidative stress and endoplasmic reticulum stress.
Lycopene regulates Nrf2 to Ameliorate Sulfamethoxazole -induced renal injury and apoptosis via inhibiting oxidative stress and Endoplasmic Reticulum stress.
Ultrasound-responsive taurine lipid nanoparticles attenuate oxidative stress and promote macrophage polarization for diabetic wound healing.
Reduced store operated calcium entry contributes to autophagy mediated escape of prostate cancer to oxaliplatin treatment.
Endoplasmic reticulum stress induces trophoblast pyroptosis via regulating CYLD during labor initiation.
The Role of Endoplasmic Reticulum Stress in Fine Particulate Matter-Induced Phenotype Switching of Vascular Smooth Muscle Cells.
SREBF1 mediates immunoparalysis of dendritic cells in sepsis by regulating lipid metabolism and endoplasmic reticulum stress.
Regulatory Role of Tubulin Beta 1 in Oocyte Endoplasmic Reticulum Stress and Mitochondrial Integrity via Transforming Growth Factor-β1 Signaling Pathway in Mice.
Carfilzomib promotes Iodine-125 seed radiation-induced apoptosis, paraptosis, and ferroptosis in esophageal squamous cell carcinoma by aggravating endoplasmic reticulum stress.
Effect of Voluntary Wheel Running on Anxiety- and Depression-Like Behaviors in Fluoride-Exposed Mice.
Constitutive Hepatic mTORC1 Activation Aggravates Alcohol-Induced Liver Injury via Endoplasmic Reticulum Stress-Mediated Ferroptosis.
Koumine mediates the generation of mtROS through the IP3R1-GRP75-VDAC1 complex to improve Citrinin induced intestinal inflammation.
Icaritin induces paraptosis in hepatocellular carcinoma cells by targeting BHLHE40 via endoplasmic reticulum stress and mitochondrial dysfunction.
COP I vesicles facilitate classical swine fever virus proliferation by transporting fatty acid synthase from the Golgi apparatus to the endoplasmic reticulum.
ROS-Dependent Endoplasmic Reticulum Stress Is Involved in Silica-Induced Pulmonary Fibrosis through the GRP78/CHOP/TXNIP/NLRP3 Signaling Pathway in Rats.
A Diet Rich in Essential Amino Acids Inhibits the Growth of HCT116 Human Colon Cancer Cell In Vitro and In Vivo.
The interaction between COX-2 and endoplasmic reticulum stress is involved in liver ischemia-reperfusion injury in mice.
Mechanisms underlying the estradiol mediated protection of yak oviduct epithelial cells against ER-Ca(2+) imbalance.
E3 ubiquitination ligase XIAP lightens diabetes-induced cognitive impairment by inactivating TXNIP-ERS-mediated neuronal injury.
Anti-lung cancer synergy of low-dose doxorubicin and PD-L1 blocker co-delivered via mild photothermia-responsive black phosphorus.
Toosendanin alleviates acute lung injury by reducing pulmonary vascular barrier dysfunction mediated by endoplasmic reticulum stress through mTOR.
Hypoxia Induced Lnc191 Upregulation Dictates the Progression of Esophageal Squamous Cell Carcinoma by Activating GRP78/ERK Pathway.
Caveolin 1 in bovine liver is associated with fatty acid-induced lipid accumulation and the endoplasmic reticulum unfolded protein response: Role in fatty liver development.
Peach Gum Polysaccharide Prevents Chemotherapy-Induced Intestinal Injury and Degenerative Behavior.
IL-17A exacerbates synovial inflammation in osteoarthritis via activation of endoplasmic reticulum stress.
Hypoxia-induced circPLOD2a/b promotes the aggressiveness of glioblastoma by suppressing XIRP1 through binding to HuR.
The Differential Expressions and Associations of Intracellular and Extracellular GRP78/Bip with Disease Activity and Progression in Rheumatoid Arthritis.
Daphnetin ameliorates diabetic cardiomyopathy by regulating inflammation and endoplasmic reticulum stress-induced apoptosis.
Perfluorooctane sulfonate causes HK-2 cell injury through ferroptosis and endoplasmic reticulum stress pathways.
HSP90 stabilizes visual cycle retinol dehydrogenase 5 in the endoplasmic reticulum by inhibiting its degradation during autophagy.
Role of MFN2 in bovine embryonic development and the mitigation of ER stress.
Taurine mechanism in preventing retinal cell damage from acute ocular hypertension through GTPBP3 regulation.
Hydrogen Sulfide Promotes TAM-M1 Polarization through Activating IRE-1α Pathway via GRP78 S-Sulfhydrylation to against Breast Cancer.
Targeting ceramide transfer protein sensitizes AML to FLT3 inhibitors via a GRP78-ATF6-CHOP axis.
Effect of Dync1h1 on Phototransduction Protein Transport and the Development and Maintenance of Photoreceptor Cells in Zebrafish.
Mesalazine alleviated the symptoms of spontaneous colitis in interleukin-10 knockout mice by regulating the STAT3/NF-κB signaling pathway.
TIM8 Deficiency in Yeast Induces Endoplasmic Reticulum Stress and Shortens the Chronological Lifespan.
Yinchen-Gancao decoction ameliorated NASH in mice by reducing hepatic lipid accumulation, inhibiting hepatic inflammatory and endoplasmic reticulum stress.
SIRT6 inhibits endoplasmic reticulum stress-mediated ferroptosis by activating Nrf2/HO-1 signaling to alleviate osteoarthritis.
Xuebijing injection alleviates septic acute kidney injury by modulating inflammation, mitochondrial dysfunction, and endoplasmic reticulum stress.
Study on the effect of HMGB1 on immune cells isolated from SLE mice.
Glabridin Alleviates Metabolic Disorders in Diet-Induced Diabetic Mice.
The T-type voltage-gated Ca(2+) channel Ca(V)3.1 involves in the disruption of respiratory epithelial barrier induced by Pasteurella multocida toxin.
Carvacrol alleviates endoplasmic reticulum stress and inflammation induced by lipopolysaccharide by enhancing endoplasmic reticulum autophagy in dairy mammary epithelial cells.
DDRGK1 preserves intervertebral disc development through ufmylation.
An Enhanced Cancer Immunogenic Cell Death Strategy: Fibrate-Oxaliplatin(IV) Conjugates with Modulating Tumor Immune Microenvironment.
Knockdown of FXYD2 inhibits mepivacaine-induced cardiomyocyte injury by activating the PI3K/AKT signaling pathway.
A combination of ethanol and arachidonic acid promotes steatosis and endoplasmic reticulum stress and impairs mitochondrial respiration in H9c2 cardiomyoblasts.
FUT3 mediated GRP78 fucosylation promotes colorectal cancer survival and proliferation under glucose restriction via PERK/ATF4/STC2 axis.
Cross-Species Insights into In Vitro Maturation Defects of the Oocyte and Identification of Crucial Regulators for Sheep Oocyte Maturation.
A study on the mechanism by which BCAT1 influences the formation of intracranial aneurysms by regulating autophagy through endoplasmic reticulum stress.
KLF10-IN-1 Attenuates RPE Cell Apoptosis and Experimental Diabetic Retinopathy Via the KLF10/PERK/eIF2α/ATF4/CHOP Pathway.
Pathology-oriented multiplexing enables integrative disease mapping.
Berberine Enhances the Sensitivity of Colorectal Cancer Cells to 5-FU Through Smoothing Endoplasmic Reticulum Stress-Mediated Autophagic Flux.
Yinchenhao Decoction Combined with Praziquantel Ameliorates Inflammation and Hepatic Fibrosis in Schistosoma japonicum-Infected Mice.
Combined downregulation of TGF-β1 and GRP78 is responsible for overcoming acquired sorafenib resistance, which is initiated by rewiring the cell surface CD44-GRP78-IGF-1R signaling circuit.
Protective effect of β-carotene against lipopolysaccharide-induced meiotic maturation defects in porcine cumulus-oocytes complexes.
Cadmium induces autophagy via IRE1 signaling pathway activated by Ca(2 +) in GC-2spd cells.
HSP90 deficiency promotes cholesteryl ester accumulation in lipid droplets via endocytosis of low-density lipoprotein.
Cardiopulmonary Bypass-Induced IL-17A Aggravates Caspase-12-Dependent Neuronal Apoptosis Through the Act1-IRE1-JNK1 Pathway.
Heat shock proteins related signature characterizes immune status and predicts prognosis of gliomas.
Dimethyl fumarate improves non-alcoholic fatty liver disease by regulating SIRT1 signal to inhibit MAMs over-enrichment.
FICD (FIC Domain Protein Adenylyl Transferase) Deficiency Protects Mice From Hypertrophy-Induced Heart Failure and Promotes BiP (Binding Immunoglobulin Protein) -Mediated Activation of the Unfolded Protein Response and Endoplasmic Reticulum-Selective Autophagy in Cardiomyocytes.
Functionally deficient UBOX5 variants and primary angle-closure glaucoma.
Glia maturation factor-β in hepatocytes enhances liver regeneration and mitigates steatosis and ballooning in zebrafish.
Klotho improves Der p1-induced bronchial epithelial cell damage by inhibiting endoplasmic reticulum stress to regulate mitochondrial function.
ETS1 promotes cisplatin resistance of NSCLC cells by promoting GRP78 transcription.
The long noncoding RNA APR attenuates PPRV infection-induced accumulation of intracellular iron to inhibit membrane lipid peroxidation and viral replication.
Small-Molecule FICD Inhibitors Suppress Endogenous and Pathologic FICD-Mediated Protein AMPylation.
PERK/Sestrin2 Signaling Pathway Mediated Autophagy Regulates Human Cardiomyocytes Apoptosis Induced by Traffic-Related PM(2.5) and Diverse Constituents.
TLR4-mediated endoplasmic reticulum stress regulates pyroptosis in macrophages infected with the Bacillus Calmette-Guérin mycobacterial.
Luteolin Modulate Endoplasmic Reticulum Stress by Targeting SIRT1 to Ameliorate DSS-Induced Ulcerative Colitis in Mice.
Effect of 1-DNJ on Oxidative Stress-Induced Apoptosis in Porcine Ovarian GCs Through Modulation of the PERK-ATF4/MFN2 Signaling Pathway.
Dissection of the potential mechanism of polystyrene microplastic exposure on cardiomyocytes.
SIGMAR1 screened by a GPCR-related classifier regulates endoplasmic reticulum stress in bladder cancer.
Mutant p53 upregulates HDAC6 to resist ER stress and facilitates Ku70 deacetylation, which prevents its degradation and mitigates DNA damage in colon cancer cells.
ITGB1 Alleviates High Glucose-Induced Myocardial Cell Injury by Inhibiting Endoplasmic Reticulum Stress and Cell Apoptosis.
Knocking-down annexin A3 suppresses inflammation, oxidative stress, apoptosis, and endoplasmic reticulum stress to attenuate sepsis-induced acute kidney injury in HK2 cells.
CRISPR/CasRx-Mediated Knockdown of Rab7B Restores Incomplete Cell Shape Induced by Pelizaeus-Merzbacher Disease-Associated PLP1 p.Ala243Val.
SIRT1 inhibits apoptosis of human lens epithelial cells through suppressing endoplasmic reticulum stress in vitro and in vivo.
Maresin-1 Attenuates Sepsis-Associated Acute Kidney Injury via Suppressing Inflammation, Endoplasmic Reticulum Stress and Pyroptosis by Activating the AMPK/SIRT3 Pathway.
Puerarin attenuates myocardial ischemic injury and endoplasmic reticulum stress by upregulating the Mzb1 signal pathway.
Protective effect of naringenin on cadmium chloride-induced renal injury via alleviating oxidative stress, endoplasmic reticulum stress, and autophagy in chickens.
Azoramide ameliorates cadmium-induced cytotoxicity by inhibiting endoplasmic reticulum stress and suppressing oxidative stress.
PKD regulates mitophagy to prevent oxidative stress and mitochondrial dysfunction during mouse oocyte maturation.
Irisflorentin improves functional recovery after spinal cord injury by protecting the blood-spinal cord barrier and promoting axonal growth.
UFL1 regulates cellular homeostasis by targeting endoplasmic reticulum and mitochondria in NEFA-stimulated bovine mammary epithelial cells via the IRE1α/XBP1 pathway.
Zinc-Mediated Endoplasmic Reticulum Stress and Metallothionein Alleviate Arsenic-Induced Cardiotoxicity in Cyprinus Carpio.
The RhoB p.S73F mutation leads to cerebral palsy through dysregulation of lipid homeostasis.
A 700 nm LED Light Activated Ru(II) Complex Destroys Tumor Cytoskeleton via Photosensitization and Photocatalysis.
Attenuation of PM2.5-Induced Lung Injury by 4-Phenylbutyric Acid: Maintenance of [Ca(2+)]i Stability between Endoplasmic Reticulum and Mitochondria.
GRP78/IRE1 and cGAS/STING pathway crosstalk through CHOP facilitates iodoacetic acid-mediated testosterone decline.
Discovery of novel quinoline scaffold selective estrogen receptor degraders (SERDs) for treatment of ER positive breast cancer with enhanced antiproliferative bioactivity through immunogenic cell death (ICD) effects.
CLCC1 promotes membrane fusion during herpesvirus nuclear egress.
Strategically engineered Au(I) complexes for orchestrated tumor eradication via chemo-phototherapy and induced immunogenic cell death.
Cepharanthine triggers ferroptosis through inhibition of NRF2 for robust ER stress against lung cancer.
TMC7 deficiency causes acrosome biogenesis defects and male infertility in mice.
DMDD, isolated from Averrhoa carambola L., ameliorates diabetic nephropathy by regulating endoplasmic reticulum stress-autophagy crosstalk.
Endoplasmic reticulum stress is attenuated by glycolysis in lymphatic malformations.
Nimbolide protects against diabetic cardiomyopathy by regulating endoplasmic reticulum stress and mitochondrial function via the Akt/mTOR pathway.
Astragaloside IV ameliorated neuroinflammation and improved neurological functions in mice exposed to traumatic brain injury by modulating the PERK-eIF2α-ATF4 signaling pathway.
Inhibiting endoplasmic reticulum stress alleviates perioperative neurocognitive disorders by reducing neuroinflammation mediated by NLRP3 inflammasome activation.
CaMKII suppresses proteotoxicity by phosphorylating BAG3 in response to proteasomal dysfunction.
Quantitative proteomics reveals the mechanism of endoplasmic reticulum stress-mediated pulmonary fibrosis in mice.
Taohong Siwu decoction alleviates cognitive impairment by suppressing endoplasmic reticulum stress and apoptosis signaling pathway in vascular dementia rats.
An atlas of the aging mouse proteome reveals the features of age-related post-transcriptional dysregulation.
Endoplasmic reticulum stress promotes oxidative stress, inflammation, and apoptosis: A novel mechanism of citrinin-induced renal injury and dysfunction.
Apoptosis mediated by crosstalk between mitochondria and endoplasmic reticulum: A possible cause of citrinin disruption of the intestinal barrier.
Liquiritigenin inhibits the migration, invasion, and EMT of prostate cancer through activating ER stress.
NUS1 Variants Cause Lennox-Gastaut Syndrome Related to Unfolded Protein Reaction Activation.
OBHSA, a novel selective estrogen receptor degrader, overcomes tamoxifen resistance through cell cycle arrest and unfolded protein response-mediated apoptosis in breast cancer.
Role of PERK-Mediated Endoplasmic Reticulum Stress in Ferroptosis Caused by Hexavalent Chromium in Chicken Hepatocytes.
Involvement of spinal NADPH oxidase 4 and endoplasmic reticulum stress in morphine-tolerant rats.
Endo-Lysosomal Network Disorder Reprograms Energy Metabolism in SorL1-Null Rat Hippocampus.
GLCCI1 alleviates GRP78-initiated endoplasmic reticulum stress-induced apoptosis of retinal ganglion cells in diabetic retinopathy by upregulating and interacting with HSP90AB1.
MIF promotes Th17 cell differentiation in rheumatoid arthritis through ATF6 signal pathway.
HNF-1β alleviates podocyte injury in lupus nephritis by maintaining endoplasmic reticulum homeostasis.
DEPTOR attenuates asthma progression by suppressing endoplasmic reticulum stress through SOD1.
SIRT1-Dependent Neuroprotection by Resveratrol in TOCP-Induced Spinal Cord Injury: Modulation of ER Stress and Autophagic Flux.
Fucoxanthin ameliorates endoplasmic reticulum stress and inhibits apoptosis and alleviates intervertebral disc degeneration in rats by upregulating Sirt1.
4-PBA exerts brain-protective effects against sepsis-associated encephalopathy in a mouse model of sepsis.
Mechanism of Qili Qiangxin Capsule for Heart Failure Based on miR133a-Endoplasmic Reticulum Stress.
Apelin‑13 reduces high glucose‑induced mitochondrial dysfunction in cochlear hair cells by inhibiting endoplasmic reticulum stress.
p20BAP31 Induces Autophagy in Colorectal Cancer Cells by Promoting PERK-Mediated ER Stress.
AGR2-mediated unconventional secretion of 14-3-3ε and α-actinin-4, responsive to ER stress and autophagy, drives chemotaxis in canine mammary tumor cells.
LY86 facilitates ox-LDL-induced lipid accumulation in macrophages by upregulating SREBP2/HMGCR expression.
Urolithin A's Role in Alleviating Severe Acute Pancreatitis via Endoplasmic Reticulum-Mitochondrial Calcium Channel Modulation.
Therapeutic Potential of Fucoidan in Alleviating Histamine-Induced Liver Injury: Insights from Mice Studies.
Juan-tong-yin potentially impacts endometriosis pathophysiology by enhancing autophagy of endometrial stromal cells via unfolded protein reaction-triggered endoplasmic reticulum stress.
Esculin suppresses the PERK-eIF2α-CHOP pathway by enhancing SIRT1 expression in oxidative stress-induced rat chondrocytes, mitigating osteoarthritis progression in a rat model.
Edaravone counteracts redox and metabolic disruptions in an emerging zebrafish model of sporadic ALS.
The down-regulation of STC2 mRNA may serve as a biomarker for death from mechanical asphyxia.
D-pinitol alleviates diabetic cardiomyopathy by inhibiting the optineurin-mediated endoplasmic reticulum stress and glycophagy signaling pathway.
A combination of PD-L1-targeted IL-15 mRNA nanotherapy and ultrasound-targeted microbubble destruction for tumor immunotherapy.
Prolyl isomerase Pin1 sculpts the immune microenvironment of colorectal cancer.
Curculigoside Attenuates Endoplasmic Reticulum Stress-Induced Epithelial Cell and Fibroblast Senescence by Regulating the SIRT1-P300 Signaling Pathway.
Rolapitant treats lung cancer by targeting deubiquitinase OTUD3.
Iron overload in hypothalamic AgRP neurons contributes to obesity and related metabolic disorders.
FBXO22 promotes glioblastoma malignant progression by mediating VHL ubiquitination and degradation.
The Effects of Endoplasmic Reticulum Stress via Intratracheal Instillation of Water-Soluble Acrylic Acid Polymer on the Lungs of Rats.
Brain transcriptomic, metabolic and mitohormesis properties associated with N-propargylglycine treatment: A prevention strategy against neurodegeneration.
DNAJC10 maintains survival and self-renewal of leukemia stem cells through PERK branch of the unfolded protein response.
Inhibition of HDAC6 with CAY10603 alleviates acute and chronic kidney injury by suppressing the ATF6 branch of UPR.
CircRNA_0088196 Regulates Trophoblast Proliferation and Apoptosis in Preeclampsia Through the miR-379-5p/HSPA5 Axis.
Melatonin alleviates endoplasmic reticulum stress and follicular granulosa cell apoptosis by regulating ATF4 to activate mTOR signaling pathway in chickens.
Deacetylated MDH1 and IDH1 aggravates PANoptosis in acute liver failure through endoplasmic reticulum stress signaling.
Using an ER-specific optogenetic mechanostimulator to understand the mechanosensitivity of the endoplasmic reticulum.
TSWIFT, a novel method for iterative staining of embedded and mounted human brain sections.
p97 inhibits integrated stress response-induced neuronal apoptosis after subarachnoid hemorrhage in mice by enhancing proteasome function.
Dietary α-Ketoglutarate Alleviates Escherichia coli LPS-Induced Intestinal Barrier Injury by Modulating the Endoplasmic Reticulum-Mitochondrial System Pathway in Piglets.
Enterovirus 3A protein disrupts endoplasmic reticulum homeostasis through interaction with GBF1.
Deubiquitylase OTUD3 regulates integrated stress response to suppress progression and sorafenib resistance of liver cancer.
Intake of Special Amino Acids Mixture Leads to Blunted Murine Colon Cancer Growth In Vitro and In Vivo.
Small molecule FICD inhibitors suppress endogenous and pathologic FICD-mediated protein AMPylation.
Copper exposure induces mitochondrial dysfunction and hepatotoxicity via the induction of oxidative stress and PERK/ATF4 -mediated endoplasmic reticulum stress.
Suppression of endoplasmic reticulum stress by 4-PBA enhanced atherosclerotic plaque stability via up-regulating CLOCK expression.
Maternal obstructive sleep apnea aggravates metabolic dysfunction-associated fatty liver disease via HMGB1-TLR4 signaling-mediated endoplasmic reticulum stress in male offspring rats.
Dietary xylo-oligosaccharides alleviates LPS-induced intestinal injury via endoplasmic reticulum-mitochondrial system pathway in piglets.
Endoplasmic reticulum stress caused by traumatic injury promotes cardiomyocyte apoptosis through acetylation modification of GRP78.
Selenium-SelK-GPX4 axis protects nucleus pulposus cells against mechanical overloading-induced ferroptosis and attenuates senescence of intervertebral disc.
Mic19 depletion impairs endoplasmic reticulum-mitochondrial contacts and mitochondrial lipid metabolism and triggers liver disease.
Cell surface GRP78: A potential therapeutic target for high glucose-induced endothelial injury.
Patulin induces ROS-dependent cardiac cell toxicity by inducing DNA damage and activating endoplasmic reticulum stress apoptotic pathway.
Methane-Rich Saline Suppresses ER-Mitochondria Contact and Activation of the NLRP3 Inflammasome by Regulating the PERK Signaling Pathway to Ameliorate Intestinal Ischemia‒Reperfusion Injury.
Pentapeptide PYRAE triggers ER stress-mediated apoptosis of breast cancer cells in mice by targeting RHBDF1-BiP interaction.
The role and mechanism of RIPK1 in vascular endothelial dysfunction in chronic kidney disease.
Lysine demethylase KDM3A alleviates hyperoxia-induced bronchopulmonary dysplasia in mice by promoting ETS1 expression.
Bile acids metabolism in the gut-liver axis mediates liver injury during lactation.
BRD4 absence inactivates endoplasmic reticulum stress to retard dehydroepiandrosterone-triggered ovarian granular cell apoptosis in polycystic ovary syndrome via GRP78.
Particulate matter induced cognitive impairments via endoplasmic reticulum stress-mediated damage to mitochondria-associated endoplasmic reticulum membranes in immature rats.
Perfluorooctane sulfonate causes damage to L-02 cells via Wnt/β-catenin signal path and endoplasmic reticulum stress pathway.
Pachymic acid ameliorates bleomycin-induced pulmonary fibrosis through inhibiting endoplasmic reticulum stress in rats.
Gelsolin alleviates rheumatoid arthritis by negatively regulating NLRP3 inflammasome activation.
Endoplasmic reticulum stress induces renal fibrosis in high‑fat diet mice via the TGF‑β/SMAD pathway.
Selenium participates in the formation of kidney stones by alleviating endoplasmic reticulum stress and apoptosis of renal tubular epithelial cells.
Sigma-1 receptor exerts protective effects on ameliorating nephrolithiasis by modulating endoplasmic reticulum-mitochondrion association and inhibiting endoplasmic reticulum stress-induced apoptosis in renal tubular epithelial cells.
TMAO induces pyroptosis of vascular endothelial cells and atherosclerosis in ApoE(-/-) mice via MBOAT2-mediated endoplasmic reticulum stress.
Grass Carp Reovirus (GCRV) infection activates the PERK-eIF2α pathway to promote the viral replication.
Cepharanthine-mediated endoplasmic reticulum stress inhibits Notch1 via binding GRP78 for suppressing hepatocellular carcinoma metastasis.
Corilagin alleviated intestinal ischemia-reperfusion injury by modulating endoplasmic reticulum stress via bonding with Bip.
TUDCA inhibits EV71 replication by regulating ER stress signaling pathway and suppressing autophagy.
Ginkgolide A enhances FoxO1 expression and reduces endoplasmic reticulum stress to mitigate osteoarthritis in mice.
Endoplasmic reticulum stress-MMRN1 positive feedback contributes to cisplatin resistance in small cell lung cancer.
Guilu Erxian glue reduces endoplasmic reticulum stress-mediated apoptosis and restores the balance of extracellular matrix synthesis and degradation in chondrocytes by inhibiting the ATF6/GRP78/CHOP signaling pathway.
SUCNR 1 promotes atherosclerosis by inducing endoplasmic reticulum stress mediated ER-mito crosstalk.
Possible Involvement of X-Box Binding Protein-1 in the Onset of Pulpitis.
miR-421-mediated suppression of FGF13 as a novel mechanism ameliorates cardiac hypertrophy by inhibiting endoplasmic reticulum stress.
Neuritin attenuates neuroinflammation and apoptosis in early brain injury after subarachnoid hemorrhage via endoplasmic reticulum stress-related inflammatory pathways.
Puerarin Attenuates Insulin Resistance by Inhibiting Endoplasmic Reticulum Stress and Suppresses Inflammation by Modulating the JNK and IKKβ/NF-κB Pathways in Epididymal White Adipose Tissue of Mice on a High-Fat Diet.
Benzo[a]pyrene exposure disrupts the organelle distribution and function of mouse oocytes.
Sex-related differences in SIRT3-mediated mitochondrial dynamics in renal ischemia/reperfusion injury.
ATF6 supports lysosomal function in tumor cells to enable ER stress-activated macroautophagy and CMA: impact on mutant TP53 expression.
Maltol Improves Peripheral Nerve Function by Inhibiting Schwann Cell Apoptosis via the PERK/eIF2α/CHOP Pathway and MME Upregulation in Diabetic Peripheral Neuropathy.
Knockdown of Rab9 Recovers Defective Morphological Differentiation Induced by Chemical ER Stress Inducer or PMD-Associated PLP1 Mutant Protein in FBD-102b Cells.
TFG regulates inner COPII coat recruitment to facilitate anterograde secretory protein transport.
Phenylbutyric acid inhibits hypoxia-induced trophoblast apoptosis and autophagy in preeclampsia via the PERK/ATF-4/CHOP pathway.
GDI2 deletion alleviates neurodegeneration and memory loss in the 5xFAD mice model of Alzheimer's disease.
Low-Intensity Extracorporeal Shock Wave Therapy Ameliorates Detrusor Hyperactivity with Impaired Contractility via Transient Potential Vanilloid Channels: A Rat Model for Ovarian Hormone Deficiency.
Up-regulation of HSP90α in HDM-induced asthma causes pyroptosis of airway epithelial cells by activating the cGAS-STING-ER stress pathway.
Ketogenic diet ameliorates high-fat diet-induced insulin resistance in mouse skeletal muscle by alleviating endoplasmic reticulum stress.
Xbp1 promotes odontoblastic differentiation through modulating mitochondrial homeostasis.
TDCPP and TiO(2) NPs aggregates synergistically induce SH-SY5Y cell neurotoxicity by excessive mitochondrial fission and mitophagy inhibition.
Triptolide induces apoptosis and cytoprotective autophagy by ROS accumulation via directly targeting peroxiredoxin 2 in gastric cancer cells.
Systems crosstalk between antiviral response and cancerous pathways via extracellular vesicles in HIV-1-associated colorectal cancer.
Mesenchymal Stem Cells Inhibit Epithelial-to-Mesenchymal Transition by Modulating the IRE1α Branch of the Endoplasmic Reticulum Stress Response.
Resveratrol Suppresses Bupivacaine-Induced Spinal Neurotoxicity in Rats by Inhibiting Endoplasmic Reticulum Stress via SIRT1 Modulation.
Quantitative Measurement of Transthyretin Mistargeting by Proximity Labeling and Parallel Reaction Monitoring.
ER translocon inhibitor ipomoeassin F inhibits triple-negative breast cancer growth via blocking ER molecular chaperones.
miR-199a-5p inhibits aortic valve calcification by targeting ATF6 and GRP78 in valve interstitial cells.
Exogenous Hydrogen Sulfide Induces A375 Melanoma Cell Apoptosis Through Overactivation of the Unfolded Protein Response.
Direct interaction of the molecular chaperone GRP78/BiP with the Newcastle disease virus hemagglutinin-neuraminidase protein plays a vital role in viral attachment to and infection of culture cells.
Heterologous DNA-prime/protein-boost immunization with a monomeric SARS-CoV-2 spike antigen redundantizes the trimeric receptor-binding domain structure to induce neutralizing antibodies in old mice.
Chrysin ameliorates synovitis and fibrosis of osteoarthritic fibroblast-like synoviocytes in rats through PERK/TXNIP/NLRP3 signaling.
Transcriptomics reveals the effects of NTRK1 on endoplasmic reticulum stress response-associated genes in human neuronal cell lines.
HMMR alleviates endoplasmic reticulum stress by promoting autophagolysosomal activity during endoplasmic reticulum stress-driven hepatocellular carcinoma progression.
Resveratrol‑mediated activation of SIRT1 inhibits the PERK‑eIF2α‑ATF4 pathway and mitigates bupivacaine‑induced neurotoxicity in PC12 cells.
Estrogens drive the endoplasmic reticulum-associated degradation and promote proto-oncogene c-Myc expression in prostate cancer cells by androgen receptor/estrogen receptor signaling.
Deubiquitinase USP19 modulates apoptotic calcium release and endoplasmic reticulum stress by deubiquitinating BAG6 in triple negative breast cancer.
Triiodothyronine positively regulates endoplasmic reticulum-associated degradation (ERAD) and promotes androgenic signaling in androgen-dependent prostate cancer cells.
Large HBV Surface Protein-Induced Unfolded Protein Response Dynamically Regulates p27 Degradation in Hepatocellular Carcinoma Progression.
Down-regulation of Hrd1 protects against myocardial ischemia-reperfusion injury by regulating PPARα to prevent oxidative stress, endoplasmic reticulum stress, and cellular apoptosis.
Exogenous spermidine alleviates diabetic cardiomyopathy via suppressing reactive oxygen species, endoplasmic reticulum stress, and Pannexin-1-mediated ferroptosis.
CD44 correlates with longevity and enhances basal ATF6 activity and ER stress resistance.
TSWIFT, a novel method for iterative staining of embedded and mounted human brain sections.
EP300 promotes ferroptosis via HSPA5 acetylation in pancreatic cancer.
Activation of endoplasmic reticulum stress by harmine suppresses the growth of esophageal squamous cell carcinoma.
Cucurbitacin B induces apoptosis in colorectal cells through reactive oxygen species generation and endoplasmic reticulum stress pathways.
SARS-COV-2 spike protein promotes RPE cell senescence via the ROS/P53/P21 pathway.
Exposure to nonylphenol in early life causes behavioural deficits related with autism spectrum disorders in rats.
Ginsenoside F4 Alleviates Skeletal Muscle Insulin Resistance by Regulating PTP1B in Type II Diabetes Mellitus.
Afzelin induces immunogenic cell death against lung cancer by targeting NQO2.
Acute Endoplasmic Reticulum Stress Suppresses Hepatic Gluconeogenesis by Stimulating MAPK Phosphatase 3 Degradation.
Metformin inhibits inflammatory response and endoplasmic reticulum stress to improve hypothalamic aging in obese mice.
MANF stimulates autophagy and restores mitochondrial homeostasis to treat autosomal dominant tubulointerstitial kidney disease in mice.
Combination therapy with HSP90 inhibitors and piperlongumine promotes ROS-mediated ER stress in colon cancer cells.
Role of SIRT2 in intestinal barrier under cold exposure.
Key Subdomains of Cerebral Dopamine Neurotrophic Factor Regulate Its Protective Function in 6-Hydroxydopamine-Lesioned PC12 Cells.
Fusaric acid inhibits proliferation and induces apoptosis through triggering endoplasmic reticulum stress in MCF-7 human breast cancer cells.
LIMK1 m(6)A-RNA methylation recognized by YTHDC2 induces 5-FU chemoresistance in colorectal cancer via endoplasmic reticulum stress and stress granule formation.
Cryptotanshinone induces apoptosis of activated hepatic stellate cells via modulating endoplasmic reticulum stress.
Vitamin K-dependent carboxylation regulates Ca(2+) flux and adaptation to metabolic stress in β cells.
Salvianolic acid A attenuates inflammation-mediated atherosclerosis by suppressing GRP78 secretion of endothelial cells.
Role of selenoprotein M knockdown in the melatonin antagonism of nickel-induced apoptosis and endoplasmic reticulum stress in mouse heart.
Pathological convergence of APP and SNCA deficiency in hippocampal degeneration of young rats.
Vitamin D receptor attenuate ischemia-reperfusion kidney injury via inhibiting ATF4.
Endoplasmic reticulum stress promotes sepsis-induced muscle atrophy via activation of STAT3 and Smad3.
Porcine reproductive and respiratory syndrome virus infection triggers autophagy via ER stress-induced calcium signaling to facilitate virus replication.
1,25(OH)(2) D(3) induced vitamin D receptor signaling negatively regulates endoplasmic reticulum-associated degradation (ERAD) and androgen receptor signaling in human prostate cancer cells.
JQ-1/bortezomib combination strongly impairs MM and PEL survival by inhibiting c-Myc and mTOR despite the activation of prosurvival mechanisms.
HSPA5 Promotes the Proliferation, Metastasis and Regulates Ferroptosis of Bladder Cancer.
Porcine Epidemic Diarrhea Virus and Its nsp14 Suppress ER Stress Induced GRP78.
Potent carotenoid astaxanthin expands the anti-cancer activity of cisplatin in human prostate cancer cells.
Atorvastatin prevents endoplasmic reticulum stress-mediated apoptosis via the Nrf2/HO-1 signaling pathway in TBI mice.
Naringin regulates endoplasmic reticulum stress and mitophagy through the ATF3/PINK1 signaling axis to alleviate pulmonary fibrosis.
Developmental growth plate cartilage formation suppressed by artificial light at night via inhibiting BMAL1-driven collagen hydroxylation.
Excessive ER-phagy contributes to ochratoxin A-induced apoptosis.
HSPA5 Promotes Attachment and Internalization of Porcine Epidemic Diarrhea Virus through Interaction with the Spike Protein and the Endo-/Lysosomal Pathway.
Discovery of an OTUD3 inhibitor for the treatment of non-small cell lung cancer.
Disturbance of neuron-microglia crosstalk mediated by GRP78 in Neuropsychiatric systemic lupus erythematosus mice.
[Cordycepin, a metabolite of Cordyceps militaris, inhibits xenograft tumor growth of tongue squamous cell carcinoma in nude mice].
HSF4 Transcriptionally Activates Autophagy by Regulating ATG9a During Lens Terminal Differentiation.
Dexamethasone-stimulated glucocorticoid receptor signaling positively regulates the endoplasmic reticulum-associated degradation (ERAD) mechanism in hepatocellular carcinoma cells.
Betulinic acid mitigates zearalenone-induced liver injury by ERS/MAPK/Nrf2 signaling pathways in mice.
Coffee prevents IQ-induced liver damage by regulating oxidative stress, inflammation, endoplasmic reticulum stress, autophagy, apoptosis, and the MAPK/NF-κB signaling pathway in zebrafish.
Xylanase improves the intestinal barrier function of Nile tilapia (Oreochromis niloticus) fed with soybean (Glycine max) meal.
Extracellular HSPA5 is autocrinally involved in the regulation of neuronal process elongation.
Marchf6 E3 ubiquitin ligase critically regulates endoplasmic reticulum stress, ferroptosis, and metabolic homeostasis in POMC neurons.
Therapeutic hyperthermia regulates complement C3 activation and suppresses tumor development through HSPA5/NFκB/CD55 pathway in nasopharyngeal carcinoma.
Endoplasmic Reticulum Stress Mediated NLRP3 Inflammasome Activation and Pyroptosis in THP-1 Macrophages Infected with Bacillus Calmette-Guérin.
Quantitative Measurement of Secretory Protein Mistargeting by Proximity Labeling and Parallel Reaction Monitoring.
Hypothermic oxygenated perfusion attenuates DCD liver ischemia-reperfusion injury by activating the JAK2/STAT3/HAX1 pathway to regulate endoplasmic reticulum stress.
AGO4 suppresses tumor growth by modulating autophagy and apoptosis via enhancing TRIM21-mediated ubiquitination of GRP78 in a p53-independent manner.
Treponema pallidum lipoprotein Tp0768 promotes the migration and adhesion of THP-1 cells to vascular endothelial cells through stress of the endoplasmic reticulum and the NF-κB/HIF-1α pathway.
Glucotropaeolin Promotes Apoptosis by Calcium Dysregulation and Attenuates Cell Migration with FOXM1 Suppression in Pancreatic Cancer Cells.
Signal sequences encode information for protein folding in the endoplasmic reticulum.
Discovery of rafoxanide as a novel agent for the treatment of non-small cell lung cancer.
Silica nanoparticles aggravated the metabolic associated fatty liver disease through disturbed amino acid and lipid metabolisms-mediated oxidative stress.
Progesterone regulates the endoplasmic reticulum-associated degradation and Unfolded Protein Response axis by mimicking the androgenic stimulation in prostate cancer cells.
ADP-ribose transferase PARP16 mediated-unfolded protein response contributes to neuronal cell damage in cerebral ischemia/reperfusion.
Jianpi-Qingchang decoction alleviates ulcerative colitis by modulating endoplasmic reticulum stress-related autophagy in intestinal epithelial cells.
Citrus peel ameliorates mucus barrier damage in HFD-fed mice.
A quantitative proteomic analyses of primary myocardial cell injury induced by heat stress in chicken embryo.
Non-Lethal Concentrations of CdCl(2) Cause Marked Alternations in Cellular Stress Responses within Exposed Sertoli Cell Line.
Methyltransferase-like 3 aggravates endoplasmic reticulum stress in preeclampsia by targeting TMBIM6 in YTHDF2-dependent manner.
Tunicamycin induces depression-like behaviors in male rats, accompanied by initiated chaperon-mediated autophagy and decreased synaptic protein expression in the hippocampus.
Mitochondrial SENP2 regulates the assembly of SDH complex under metabolic stress.
Polystyrene Microplastics Induced Ovarian Toxicity in Juvenile Rats Associated with Oxidative Stress and Activation of the PERK-eIF2α-ATF4-CHOP Signaling Pathway.
NRF2 and Bip Interconnection Mediates Resistance to the Organometallic Ruthenium-Cymene Bisdemethoxycurcumin Complex Cytotoxicity in Colon Cancer Cells.
Decreased syntaxin17 expression contributes to the pathogenesis of acute pancreatitis in murine models by impairing autophagic degradation.
Lithium chloride induces apoptosis by activating endoplasmic reticulum stress in pancreatic cancer.
EIF2α/ATF4 pathway enhances proliferation of mesangial cell via cyclin D1 during endoplasmic reticulum stress in IgA nephropathy.
Exogenous H(2) S promotes ubiquitin-mediated degradation of SREBP1 to alleviate diabetic cardiomyopathy via SYVN1 S-sulfhydration.
An investigation of the endoplasmic reticulum stress in obesity exposure in the prenatal period.
Lead and cadmium co-exposure modified PC12 viability and ER stress: study from a 3 × 3 factorial design.
Nutrient deprivation alters the rate of COPII subunit recruitment at ER subdomains to tune secretory protein transport.
NTRK1-mediated protection against manganese-induced neurotoxicity and cell apoptosis via IGF2 in SH-SY5Y cells.
Role of SYVN1 in the control of airway remodeling in asthma protection by promoting SIRT2 ubiquitination and degradation.
Corilagin enhances the anti-tumor activity of 5-FU by downregulating the expression of GRP 78.
ER Stress-Perturbed Intracellular Protein O-GlcNAcylation Aggravates Podocyte Injury in Diabetes Nephropathy.
Glycyrrhetinic acid attenuates endoplasmic reticulum stress-induced hepatocyte apoptosis via CHOP/DR5/Caspase 8 pathway in cholestasis.
Reduced Proteolipid Protein 2 promotes endoplasmic reticulum stress-related apoptosis and increases drug sensitivity in acute myeloid leukemia.
XBP1s gene of endoplasmic reticulum stress enhances proliferation and osteogenesis of human periodontal ligament cells.
The therapeutic effect of tanshinone IIA in mouse astrocytes after treatment with Angiostrongylus cantonensis fifth-stage larval excretory-secretory products.
Dipyridamole enhances the anti-cancer ability of aspirin against colorectal cancer by inducing apoptosis in an unfolded protein response-dependent manner.
RCN2 promotes Nasopharyngeal carcinoma progression by curbing Calcium flow and Mitochondrial apoptosis.
LINC00355 Mediates CTNNBIP1 Promoter Methylation and Promotes Endoplasmic Reticulum Stress-Induced Podocyte Injury in Diabetic Nephropathy.
Exogenous hydrogen sulfide alleviates hepatic endoplasmic reticulum stress via SIRT1/FoxO1/PCSK9 pathway in NAFLD.
Tanshinone IIA ameliorates experimental diabetic cardiomyopathy by inhibiting endoplasmic reticulum stress in cardiomyocytes via SIRT1.
Fluoride-Induced Cortical Toxicity in Rats: the Role of Excessive Endoplasmic Reticulum Stress and Its Mediated Defective Autophagy.
Zinc deficiency causes oxidative stress, endoplasmic reticulum stress, apoptosis and inflammation in hepatocytes in grass carp.
Salidroside ameliorates acetaminophen-induced acute liver injury through the inhibition of endoplasmic reticulum stress-mediated ferroptosis by activating the AMPK/SIRT1 pathway.
4-phenylbutyric acid re-trafficking hERG/G572R channel protein by modulating the endoplasmic reticulum stress-associated chaperones and endoplasmic reticulum-associated degradation gene.
Advanced oxidation protein products induce Paneth cells defects by endoplasmic reticulum stress in Crohn's disease.
PARP1-catalyzed PARylation of YY1 mediates endoplasmic reticulum stress in granulosa cells to determine primordial follicle activation.
Interaction of Bmal1 and eIF2α/ATF4 pathway was involved in Shuxie compound alleviation of circadian rhythm disturbance-induced hepatic endoplasmic reticulum stress.
PARP16-Mediated Stabilization of Amyloid Precursor Protein mRNA Exacerbates Alzheimer's Disease Pathogenesis.
Cannabidiol Protects Striatal Neurons by Attenuating Endoplasmic Reticulum Stress.
FUT2-dependent fucosylation of HYOU1 protects intestinal stem cells against inflammatory injury by regulating unfolded protein response.
Low temperature plasma protects against inflammatory agents-mediated dysfunction of theca cells via enhancing MANF expression.
cFLIP(L) Alleviates Myocardial Ischemia-Reperfusion Injury by Inhibiting Endoplasmic Reticulum Stress.
Dihydroartemisinin elicits immunogenic death through ferroptosis-triggered ER stress and DNA damage for lung cancer immunotherapy.
Apurinic/apyrimidinic endonuclease 1 regulates palmitic acid-mediated apoptosis in cardiomyocytes via endoplasmic reticulum stress.
Antitumoral effects of Bortezomib in malignant mesothelioma: evidence of mild endoplasmic reticulum stress in vitro and activation of T cell response in vivo.
Citrinin Exposure Induced Testicular Damage and Spermatogenesis Disorder by Triggering Endoplasmic Reticulum Stress.
The cervical lymph node contributes to peripheral inflammation related to Parkinson's disease.
The Mechanism of Lipopolysaccharide Escaping the Intestinal Barrier in Megalobrama amblycephala Fed a High-Fat Diet.
Effects of folic acid on oxidative damage of kidney in lead-exposed rats.
Jianpi Qingchang Decoction Ameliorates Chronic Colitis in Piroxicam-Induced IL-10 Knockout Mice by Inhibiting Endoplasmic Reticulum Stress.
HSPA5 Inhibitor Meliorate DSS-Induced Colitis through HSPA1A/CHIP.
EGCG Enhances the Chemosensitivity of Colorectal Cancer to Irinotecan through GRP78-MediatedEndoplasmic Reticulum Stress.
Naringenin Alleviates Renal Ischemia Reperfusion Injury by Suppressing ER Stress-Induced Pyroptosis and Apoptosis through Activating Nrf2/HO-1 Signaling Pathway.
LARS2 Regulates Apoptosis via ROS-Mediated Mitochondrial Dysfunction and Endoplasmic Reticulum Stress in Ovarian Granulosa Cells.
Saikosaponin D Inducing Apoptosis and Autophagy through the Activation of Endoplasmic Reticulum Stress in Glioblastoma.
Deletion of ACLY Disrupts Histone Acetylation and IL-10 Secretion in Trophoblasts, Which Inhibits M2 Polarization of Macrophages: A Possible Role in Recurrent Spontaneous Abortion.
Negative Feedback of the cAMP/PKA Pathway Regulates the Effects of Endoplasmic Reticulum Stress-Induced NLRP3 Inflammasome Activation on Type II Alveolar Epithelial Cell Pyroptosis as a Novel Mechanism of BLM-Induced Pulmonary Fibrosis.
Oleoylethanolamide Alleviates Hepatic Ischemia-Reperfusion Injury via Inhibiting Endoplasmic Reticulum Stress-Associated Apoptosis.
Ursolic Acid Derivative UA232 Promotes Tumor Cell Apoptosis by Inducing Endoplasmic Reticulum Stress and Lysosomal Dysfunction.
A Novel ER Stress Mediator TMTC3 Promotes Squamous Cell Carcinoma Progression by Activating GRP78/PERK Signaling Pathway.
Didymin Ameliorates Liver Fibrosis by Alleviating Endoplasmic Reticulum Stress and Glycerophospholipid Metabolism: Based on Transcriptomics and Metabolomics.
Pitavastatin protects against neomycin-induced ototoxicity through inhibition of endoplasmic reticulum stress.
Cryptotanshinone alleviates myocardial ischemia and reperfusion injury in rats to mitigate ER stress-dependent apoptosis by modulating the JAK1/STAT3 axis.
TM9SF4 Is a Crucial Regulator of Inflammation and ER Stress in Inflammatory Bowel Disease.
PERK Regulates the Sensitivity of Hepatocellular Carcinoma Cells to High-LET Carbon Ions via either Apoptosis or Ferroptosis.
Endoplasmic reticulum stress promoted acinar cell necroptosis in acute pancreatitis through cathepsinB-mediated AP-1 activation.
Melatonin promotes sirtuin 1 expression and inhibits IRE1α-XBP1S-CHOP to reduce endoplasmic reticulum stress-mediated apoptosis in chondrocytes.
EspF of Enterohemorrhagic Escherichia coli Enhances Apoptosis via Endoplasmic Reticulum Stress in Intestinal Epithelial Cells: An Isobaric Tags for Relative and Absolute Quantitation-Based Comparative Proteomic Analysis.
Cold Exposure Induces Intestinal Barrier Damage and Endoplasmic Reticulum Stress in the Colon via the SIRT1/Nrf2 Signaling Pathway.
C9orf72 regulates the unfolded protein response and stress granule formation by interacting with eIF2α.
Protection of catalpol against triptolide-induced hepatotoxicity by inhibiting excessive autophagy via the PERK-ATF4-CHOP pathway.
COG4 mutation in Saul-Wilson syndrome selectively affects secretion of proteins involved in chondrogenesis in chondrocyte-like cells.
Adenosine Kinase Inhibition Prevents Severe Acute Pancreatitis via Suppressing Inflammation and Acinar Cell Necroptosis.
Endoplasmic Reticulum Stress Is Involved in Muscular Pathogenesis in Idiopathic Inflammatory Myopathies.
HSPA5 repressed ferroptosis to promote colorectal cancer development by maintaining GPX4 stability.
Substitution of SERCA2 Cys(674) accelerates aortic aneurysm by inducing endoplasmic reticulum stress and promoting cell apoptosis.
Zearalenone Promotes LPS-Induced Oxidative Stress, Endoplasmic Reticulum Stress, and Accelerates Bovine Mammary Epithelial Cell Apoptosis.
LncRNA-SUSAJ1 Activates the ER Stress Pathway Inhibiting JEV Proliferation by Promoting PK15 Cells Apoptosis.
Elaiophylin triggers paraptosis and preferentially kills ovarian cancer drug-resistant cells by inducing MAPK hyperactivation.
Bortezomib prodrug catalytic nanoreactor for chemo/chemodynamic therapy and macrophage re-education.
Cold exposure-induced endoplasmic reticulum stress regulates autophagy through the SIRT2/FoxO1 signaling pathway.
Substitution of the SERCA2 Cys(674) reactive thiol accelerates atherosclerosis by inducing endoplasmic reticulum stress and inflammation.
Severe congenital myasthenic syndromes caused by agrin mutations affecting secretion by motoneurons.
Sodium butyrate reduces overnutrition-induced microglial activation and hypothalamic inflammation.
Targeting A-kinase anchoring protein 12 phosphorylation in hepatic stellate cells regulates liver injury and fibrosis in mouse models.
SYNJ2BP Improves the Production of Lentiviral Envelope Protein by Facilitating the Formation of Mitochondrion-Associated Endoplasmic Reticulum Membrane.
Exploring the molecular mechanisms underlie the endoplasmic reticulum stress-mediated methylmercury-induced neuronal developmental damage.
Melatonin alleviates PM(2.5) -induced glucose metabolism disorder and lipidome alteration by regulating endoplasmic reticulum stress.
Galectin‑1 binds GRP78 to promote the proliferation and metastasis of gastric cancer.
Vitamin C modulates the levels of several proteins of the mitochondrial complex III and its activity in the mouse liver.
OL-FS13 alleviates experimental cerebral ischemia-reperfusion injury.
Pterostilbene attenuates intrauterine growth retardation-induced colon inflammation in piglets by modulating endoplasmic reticulum stress and autophagy.
CircZXDC Promotes Vascular Smooth Muscle Cell Transdifferentiation via Regulating miRNA-125a-3p/ABCC6 in Moyamoya Disease.
Aging Impairs Adaptive Unfolded Protein Response and Drives Beta Cell Dedifferentiation in Humans.
Hydrogen Sulfide Regulates SERCA2a Ubiquitylation via Muscle RING Finger-1 S-Sulfhydration to Affect Cardiac Contractility in db/db Mice.
Autophagy Mediates Escherichia Coli-Induced Cellular Inflammatory Injury by Regulating Calcium Mobilization, Mitochondrial Dysfunction, and Endoplasmic Reticulum Stress.
Inhibition of human peptide deformylase by actinonin sensitizes glioblastoma cells to temozolomide chemotherapy.
Zinc Alleviates Arsenic-Induced Inflammation and Apoptosis in the Head Kidney of Common Carp by Inhibiting Oxidative Stress and Endoplasmic Reticulum Stress.
Manganese Mitigates Heat Stress-Induced Apoptosis by Alleviating Endoplasmic Reticulum Stress and Activating the NRF2/SOD2 Pathway in Primary Chick Embryonic Myocardial Cells.
Dihydroartemisinin alleviates steatosis and inflammation in nonalcoholic steatohepatitis by decreasing endoplasmic reticulum stress and oxidative stress.
Azithromycin alleviates the severity of rheumatoid arthritis by targeting the unfolded protein response component of glucose-regulated protein 78 (GRP78).
Fucoidan protects the pancreas and improves glucose metabolism through inhibiting inflammation and endoplasmic reticulum stress in T2DM rats.
Endoplasmic reticulum chaperone genes encode effectors of long-term memory.
Estrogen inhibits endoplasmic reticulum stress and ameliorates myocardial ischemia/reperfusion injury in rats by upregulating SERCA2a.
Pathogenic Role of Endoplasmic Reticulum Stress in Diabetic Corneal Endothelial Dysfunction.
Gestational exposure to BDE-209 induces placental injury via the endoplasmic reticulum stress-mediated PERK/ATF4/CHOP signaling pathway.
Protective Effects of Taraxasterol against Deoxynivalenol-Induced Damage to Bovine Mammary Epithelial Cells.
A rapid and simple procedure for the isolation and cultivation of fibroblast-like cells from medaka and zebrafish embryos and fin clip biopsies.
Contribution of Endoplasmic Reticulum Stress to the Clinical Instability of Carotid Plaques in Human Carotid Stenosis.
Recombinant ACE2 protein protects against acute lung injury induced by SARS-CoV-2 spike RBD protein.
ATF6 prevents DNA damage and cell death in colon cancer cells undergoing ER stress.
Intravenously transplanted mesenchymal stromal cells: a new endocrine reservoir for cardioprotection.
Exposure of mouse oocytes to N,N-dimethylformamide impairs mitochondrial functions and reduces oocyte quality.
The cardiotoxicity of asthmatic rats after traffic-related PM(2.5) and water-soluble components exposure mediated by endoplasmic reticulum stress and autophagy.
Peste des petits ruminants virus induces ERS-mediated autophagy to promote virus replication.
ER stress-related protein, CHOP, may serve as a biomarker of mechanical asphyxia: a primary study.
Glyphosate exposure deteriorates oocyte meiotic maturation via induction of organelle dysfunctions in pigs.
The Role of Ferroptosis in the Damage of Human Proximal Tubule Epithelial Cells Caused by Perfluorooctane Sulfonate.
COVID-19 lung disease shares driver AT2 cytopathic features with Idiopathic pulmonary fibrosis.
Monitoring Protein Import into the Endoplasmic Reticulum in Living Cells with Proximity Labeling.
TSG-6 released from adipose stem cells-derived small extracellular vesicle protects against spinal cord ischemia reperfusion injury by inhibiting endoplasmic reticulum stress.
The impairment of DDR reduces XBP1s, further increasing DNA damage, and triggers autophagy via PERK/eIF2alpha in MM and IRE1alpha/JNK1/2 in PEL cells.
TRPV4 contributes to ER stress and inflammation: implications for Parkinson's disease.
Down-regulating GRP78 reverses pirarubicin resistance of triple negative breast cancer by miR-495-3p mimics and involves the p-AKT/mTOR pathway.
Nrf2 loss of function exacerbates endoplasmic reticulum stress-induced apoptosis in TBI mice.
Zinc Supplementation Enhances the Pro-Death Function of UPR in Lymphoma Cells Exposed to Radiation.
The PERK/PKR-eIF2α Pathway Negatively Regulates Porcine Hemagglutinating Encephalomyelitis Virus Replication by Attenuating Global Protein Translation and Facilitating Stress Granule Formation.
Glucose consumption of vascular cell types in culture: toward optimization of experimental conditions.
Inhibition of the miR-193b-3p protects against oxidized low-density lipoprotein-induced HUVECs injury by upregulating ALDH2.
Sigma-1 receptor activity in primary sensory neurons is a critical driver of neuropathic pain.
Therapeutic effect and mechanism of 4-phenyl butyric acid on renal ischemia-reperfusion injury in mice.
Zinc Protects against Heat Stress-Induced Apoptosis via the Inhibition of Endoplasmic Reticulum Stress in TM3 Leydig Cells.
ATF6-Mediated Unfolded Protein Response Facilitates Adeno-associated Virus 2 (AAV2) Transduction by Releasing the Suppression of the AAV Receptor on Endoplasmic Reticulum Stress.
Changes of flavin-containing monooxygenases and trimethylamine-N-oxide may be involved in the promotion of non-alcoholic fatty liver disease by intestinal microbiota metabolite trimethylamine.
Perfluorooctanoic acid induces hepatocellular endoplasmic reticulum stress and mitochondrial-mediated apoptosis in vitro via endoplasmic reticulum-mitochondria communication.
A missing piece of the puzzle in pulmonary fibrosis: anoikis resistance promotes fibroblast activation.
Transketolase promotes colorectal cancer metastasis through regulating AKT phosphorylation.
African Swine Fever Virus K205R Induces ER Stress and Consequently Activates Autophagy and the NF-κB Signaling Pathway.
Endoplasmic reticulum stress mediates parathyroid hormone-induced apoptosis in vascular smooth muscle cells.
The Mechano-Ubiquitinome of Articular Cartilage: Differential Ubiquitination and Activation of a Group of ER-Associated DUBs and ER Stress Regulators.
Exosome modification to better alleviates endoplasmic reticulum stress induced chondrocyte apoptosis and osteoarthritis.
PRDX6 inhibits hepatic stellate cells activation and fibrosis via promoting MANF secretion.
Corynoxine suppresses pancreatic cancer growth primarily via ROS-p38 mediated cytostatic effects.
Gut dysbacteriosis attenuates resistance to Mycobacterium bovis infection by decreasing cyclooxygenase 2 to inhibit endoplasmic reticulum stress.
Endoplasmic Reticulum Chemical Chaperone 3-Hydroxy-2-Naphthoic Acid Reduces Angiotensin II-Induced Vascular Remodeling and Hypertension In Vivo and Protein Synthesis In Vitro.
Deficiency of CFB attenuates renal tubulointerstitial damage by inhibiting ceramide synthesis in diabetic kidney disease.
Endosomal lipid signaling reshapes the endoplasmic reticulum to control mitochondrial function.
Enhanced tumor targeting and timely viral release of mesenchymal stem cells/oncolytic virus complex due to GRP78 and inducible E1B55K expressions greatly increase the antitumor effect of systemic treatment.
Translational control by maternal Nanog promotes oogenesis and early embryonic development.
COVID-19 lung disease shares driver AT2 cytopathic features with Idiopathic pulmonary fibrosis.
Sodium selenite attenuates zearalenone-induced apoptosis through inhibition of endoplasmic reticulum stress in goat trophoblast cells.
A novel 8-hydroxyquinoline derivative induces breast cancer cell death through paraptosis and apoptosis.
Inhibition of USP14 influences alphaherpesvirus proliferation by degrading viral VP16 protein via ER stress-triggered selective autophagy.
Non-Esterified Fatty Acid Induces ER Stress-Mediated Apoptosis via ROS/MAPK Signaling Pathway in Bovine Mammary Epithelial Cells.
Interleukin-33 regulates the endoplasmic reticulum stress of human myometrium via an influx of calcium during initiation of labor.
Lysyl hydroxylase 2 mediated collagen post-translational modifications and functional outcomes.
Si-Wu Water Extracts Protect against Colonic Mucus Barrier Damage by Regulating Muc2 Mucin Expression in Mice Fed a High-Fat Diet.
Concomitant Inhibition of IRE1α/XBP1 Axis of UPR and PARP: A Promising Therapeutic Approach against c-Myc and Gammaherpesvirus-Driven B-Cell Lymphomas.
TIMP2 mediates endoplasmic reticulum stress contributing to sepsis-induced acute kidney injury.
Endoplasmic reticulum stress affects mouse salivary protein secretion induced by chronic administration of an α(1)-adrenergic agonist.
ZBM-H-induced activation of GRP78 ATPase promotes apoptosis via annexin A7 in A549 lung cancer cells.
Citrinin-Induced Hepatotoxicity in Mice Is Regulated by the Ca(2+)/Endoplasmic Reticulum Stress Signaling Pathway.
Dietary Tryptophan Supplementation Improves Antioxidant Status and Alleviates Inflammation, Endoplasmic Reticulum Stress, Apoptosis, and Pyroptosis in the Intestine of Piglets after Lipopolysaccharide Challenge.
Exercise activates autophagy and regulates endoplasmic reticulum stress in muscle of high-fat diet mice to alleviate insulin resistance.
Chlorogenic acid improves the intestinal barrier by relieving endoplasmic reticulum stress and inhibiting ROCK/MLCK signaling pathways.
Nicotinamide mononucleotide alleviates heat stress-induced oxidative stress and apoptosis in BMECs through reducing mitochondrial damage and endoplasmic reticulum stress.
Long noncoding RNA SH3PXD2A-AS1 promotes NSCLC proliferation and accelerates cell cycle progression by interacting with DHX9.
GPX4 degradation via chaperone-mediated autophagy contributes to antimony-triggered neuronal ferroptosis.
Eicosapentaenoic Acid-Induced Autophagy Attenuates Intervertebral Disc Degeneration by Suppressing Endoplasmic Reticulum Stress, Extracellular Matrix Degradation, and Apoptosis.
Plasma Purification Treatment Relieves the Damage of Hyperlipidemia to PBMCs.
Pharmacological Activating Transcription Factor 6 Activation Is Beneficial for Liver Retrieval With ex vivo Normothermic Mechanical Perfusion From Cardiac Dead Donor Rats.
Curcumin Alleviates Palmitic Acid-Induced LOX-1 Upregulation by Suppressing Endoplasmic Reticulum Stress in HUVECs.
Mechanosensitive Ion Channel Piezo1 Activated by Matrix Stiffness Regulates Oxidative Stress-Induced Senescence and Apoptosis in Human Intervertebral Disc Degeneration.
Wenxin Granules Regulate Endoplasmic Reticulum Stress Unfolded Protein Response and Improve Ventricular Remodeling on Rats with Myocardial Infarction.
Ginkgo Biloba Extract EGB761 Ameliorates the Extracellular Matrix Accumulation and Mesenchymal Transformation of Renal Tubules in Diabetic Kidney Disease by Inhibiting Endoplasmic Reticulum Stress.
The Dietary Supplement γ-Oryzanol Attenuates Hepatic Ischemia Reperfusion Injury via Inhibiting Endoplasmic Reticulum Stress and HMGB1/NLRP3 Inflammasome.
Endophilin A2-mediated alleviation of endoplasmic reticulum stress-induced cardiac injury involves the suppression of ERO1α/IP(3)R signaling pathway.
Sini San Inhibits Chronic Psychological Stress-Induced Breast Cancer Stemness by Suppressing Cortisol-Mediated GRP78 Activation.
Autophagy Blockade by Ai Du Qing Formula Promotes Chemosensitivity of Breast Cancer Stem Cells Via GRP78/β-Catenin/ABCG2 Axis.
Dl-3-n-Butylphthalide Ameliorates Diabetic Nephropathy by Ameliorating Excessive Fibrosis and Podocyte Apoptosis.
Hypothermic oxygenated perfusion with defatting cocktail further improves steatotic liver grafts in a transplantation rat model.
Exosomal ERp44 derived from ER-stressed cells strengthens cisplatin resistance of nasopharyngeal carcinoma.
Role of UPR Sensor Activation in Cell Death-Survival Decision of Colon Cancer Cells Stressed by DPE Treatment.
Autophagy protein NRBF2 attenuates endoplasmic reticulum stress-associated neuroinflammation and oxidative stress via promoting autophagosome maturation by interacting with Rab7 after SAH.
Hydrogen sulphide reduced the accumulation of lipid droplets in cardiac tissues of db/db mice via Hrd1 S-sulfhydration.
Osthole induces apoptosis of the HT-29 cells via endoplasmic reticulum stress and autophagy.
GnRHa protects the ovarian reserve by reducing endoplasmic reticulum stress during cyclophosphamide-based chemotherapy.
Naringenin attenuates endoplasmic reticulum stress, reduces apoptosis, and improves functional recovery in experimental traumatic brain injury.
Targeting GRP78 enhances the sensitivity of HOS osteosarcoma cells to pyropheophorbide-α methyl ester-mediated photodynamic therapy via the Wnt/β-catenin signaling pathway.
Cytotoxic BODIPY-Appended Half-Sandwich Iridium(III) Complex Forms Protein Adducts and Induces ER Stress.
2-Amino-3-Methylimidazo[4,5-f]quinoline Triggering Liver Damage by Inhibiting Autophagy and Inducing Endoplasmic Reticulum Stress in Zebrafish (Danio rerio).
SAA1 is transcriptionally activated by STAT3 and accelerates renal interstitial fibrosis by inducing endoplasmic reticulum stress.
The seed oil of Paeonia ludlowii ameliorates Aβ25-35-induced Alzheimer's disease in rats.
Macrophage-derived exosomes mediate silica-induced pulmonary fibrosis by activating fibroblast in an endoplasmic reticulum stress-dependent manner.
Roles of endoplasmic reticulum stress in 2,2',4,4'-tetrabromodiphenylether-induced thyroid cell apoptosis and autophagy.
PGE2 Released by Pancreatic Cancer Cells Undergoing ER Stress Transfers the Stress to DCs Impairing Their Immune Function.
SMYD3-PARP16 axis accelerates unfolded protein response and mediates neointima formation.
Heme cytotoxicity is the consequence of endoplasmic reticulum stress in atherosclerotic plaque progression.
The role of ATF6 in Cr(VI)-induced apoptosis in DF-1 cells.
Sirtuin 6 ameliorates alcohol-induced liver injury by reducing endoplasmic reticulum stress in mice.
Ubiquitin-proteasome System Is a Promising Target for Killing Cisplatin-resistant Bladder Cancer Cells.
Lipotoxicity suppresses the synthesis of growth hormone in pituitary somatotrophs via endoplasmic reticulum stress.
Characterization of a complex phenotype (fever-dependent recurrent acute liver failure and osteogenesis imperfecta) due to NBAS and P4HB variants.
Endoplasmic reticulum stress manipulates autophagic response that antagonizes polybrominated diphenyl ethers quinone induced cytotoxicity in microglial BV2 cells.
Trim21-mediated HIF-1α degradation attenuates aerobic glycolysis to inhibit renal cancer tumorigenesis and metastasis.
Neutrophil extracellular traps impair intestinal barrier functions in sepsis by regulating TLR9-mediated endoplasmic reticulum stress pathway.
The mechanism of 5-aminolevulinic acid photodynamic therapy in promoting endoplasmic reticulum stress in the treatment of HR-HPV-infected HeLa cells.
Polybrominated diphenyl ethers quinone-induced intracellular protein oxidative damage triggers ubiquitin-proteasome and autophagy-lysosomal system activation in LO2 cells.
Choline attenuates heat stress-induced oxidative injury and apoptosis in bovine mammary epithelial cells by modulating PERK/Nrf-2 signaling pathway.
Untargeted metabolomics and transcriptomics identified glutathione metabolism disturbance and PCS and TMAO as potential biomarkers for ER stress in lung.
Thrombospondin 1-induced exosomal proteins attenuate hypoxia-induced paraptosis in corneal epithelial cells and promote wound healing.
Autophagy impairment as a key feature for acetaminophen-induced ototoxicity.
Bioactivation of clozapine by mitochondria of the murine heart: Possible cause of cardiotoxicity.
MicroRNA-150 affects endoplasmic reticulum stress via MALAT1-miR-150 axis-mediated NF-κB pathway in LPS-challenged HUVECs and septic mice.
Microcystin-leucine arginine induced the apoptosis of GnRH neurons by activating the endoplasmic reticulum stress resulting in a decrease of serum testosterone level in mice.
Activation of the G Protein-Coupled Estrogen Receptor Prevented the Development of Acute Colitis by Protecting the Crypt Cell.
Boron Attenuates Heat Stress-Induced Apoptosis by Inhibiting Endoplasmic Reticulum Stress in Mouse Granulosa Cells.
Central role of TRAP1 in the ameliorative effect of oleanolic acid on the mitochondrial-mediated and endoplasmic reticulum stress-excitated apoptosis induced by ochratoxin A.
Receptor-Mediated ER Export of Lipoproteins Controls Lipid Homeostasis in Mice and Humans.
A point mutation in the Pdia6 gene results in loss of pancreatic β-cell identity causing overt diabetes.
Endoplasmic reticulum stress pathway mediates T-2 toxin-induced chondrocyte apoptosis.
The Dual Histone Deacetylase-Proteasome Inhibitor RTS-V5 Acts Synergistically With Ritonavir to Induce Endoplasmic Reticulum Stress in Bladder Cancer Cells.
Non-canonical activation of the ER stress sensor ATF6 by Legionella pneumophila effectors.
ChREBP deficiency alleviates apoptosis by inhibiting TXNIP/oxidative stress in diabetic nephropathy.
GJB1 mutations c.212T>G and c.311A>C induce apoptosis and inwardly rectifying potassium current changes in X-linked Charcot-Marie-Tooth type 1.
Sulforaphane protects against oxidative stress‑induced apoptosis via activating SIRT1 in mouse osteoarthritis.
The ameliorative effect of terpinen-4-ol on ER stress-induced vascular calcification depends on SIRT1-mediated regulation of PERK acetylation.
Integration of Metabolomics and Transcriptomics Reveals Ketone Body and Lipid Metabolism Disturbance Related to ER Stress in the Liver.
TMEM41B acts as an ER scramblase required for lipoprotein biogenesis and lipid homeostasis.
Ultrabright plasmonic fluor nanolabel-enabled detection of a urinary ER stress biomarker in autosomal dominant tubulointerstitial kidney disease.
ARFGAP1 binds to classical swine fever virus NS5A protein and enhances CSFV replication in PK-15 cells.
Changes in hepatic triglyceride content with the activation of ER stress and increased FGF21 secretion during pregnancy.
Glutamate-Cysteine Ligase Catalytic Subunit Attenuated Hepatitis C Virus-Related Liver Fibrosis and Suppressed Endoplasmic Reticulum Stress.
Methane-Rich Saline Alleviates CA/CPR Brain Injury by Inhibiting Oxidative Stress, Microglial Activation-Induced Inflammatory Responses, and ER Stress-Mediated Apoptosis.
Therapeutic Role of Protein Tyrosine Phosphatase 1B in Parkinson's Disease via Antineuroinflammation and Neuroprotection In Vitro and In Vivo.
Diazoxide Protects against Myocardial Ischemia/Reperfusion Injury by Moderating ERS via Regulation of the miR-10a/IRE1 Pathway.
Salvianolic Acid B Improves Chronic Mild Stress-Induced Depressive Behaviors in Rats: Involvement of AMPK/SIRT1 Signaling Pathway.
Chlorin A-mediated photodynamic therapy induced apoptosis in human cholangiocarcinoma cells via impaired autophagy flux.
Role of Endoplasmic Reticulum Stress in Otitis Media.
ANKS4B Restricts Replication of Zika Virus by Downregulating the Autophagy.
Maimendong Decoction Improves Pulmonary Function in Rats With Idiopathic Pulmonary Fibrosis by Inhibiting Endoplasmic Reticulum Stress in AECIIs.
A paralog-specific role of COPI vesicles in the neuronal differentiation of mouse pluripotent cells.
Asiatic acid ameliorates acute hepatic injury by reducing endoplasmic reticulum stress and triggering hepatocyte autophagy.
Reactive oxygen species mediate anlotinib-induced apoptosis via activation of endoplasmic reticulum stress in pancreatic cancer.
Liraglutide Up-regulation Thioredoxin Attenuated Müller Cells Apoptosis in High Glucose by Regulating Oxidative Stress and Endoplasmic Reticulum Stress.
ROS-mediated PERK-eIF2α-ATF4 pathway plays an important role in arsenite-induced L-02 cells apoptosis via regulating CHOP-DR5 signaling.
Melatonin inhibits oxalate-induced endoplasmic reticulum stress and apoptosis in HK-2 cells by activating the AMPK pathway.
Neuroprotective mechanism of L-cysteine after subarachnoid hemorrhage.
T-type calcium channel blockade induces apoptosis in C2C12 myotubes and skeletal muscle via endoplasmic reticulum stress activation.
IL-32 induces epithelial-mesenchymal transition by triggering endoplasmic reticulum stress in A549 cells.
Design, synthesis, and biological evaluation of 5-((8-methoxy-2-methylquinolin-4-yl)amino)-1H-indole-2-carbohydrazide derivatives as novel Nur77 modulators.
Protective effects of pterostilbene against hepatic damage, redox imbalance, mitochondrial dysfunction, and endoplasmic reticulum stress in weanling piglets.
Aging is associated with increased TRB3, ER stress, and hepatic glucose production in the liver of rats.
Ubiquitin ligase CHIP regulates OTUD3 stability and suppresses tumour metastasis in lung cancer.
CDK5RAP3, a Novel Nucleoplasmic Shuttle, Deeply Regulates HSF1-Mediated Heat Stress Response and Protects Mammary Epithelial Cells from Heat Injury.
TRPV4 contributes to ER stress: Relation to apoptosis in the MPP(+)-induced cell model of Parkinson's disease.
Acupuncture protects against cerebral ischemia-reperfusion injury via suppressing endoplasmic reticulum stress-mediated autophagy and apoptosis.
Cleavage of cyclic AMP-responsive element-binding protein H aggravates myocardial hypoxia reperfusion injury in a hepatocyte-myocardial cell co-culture system.
Exogenous spermine attenuates rat diabetic cardiomyopathy via suppressing ROS-p53 mediated downregulation of calcium-sensitive receptor.
Pyruvate alleviates high glucose-induced endoplasmic reticulum stress and apoptosis in HK-2 cells.
miR-384-5p promotes spinal cord injury recovery in rats through suppressing of autophagy and endoplasmic reticulum stress.
Knockout of DNase1l1l abrogates lens denucleation process and causes cataract in zebrafish.
Xanthatin induces glioma cell apoptosis and inhibits tumor growth via activating endoplasmic reticulum stress-dependent CHOP pathway.
Blockade of HSP70 by VER-155008 synergistically enhances bortezomib-induced cytotoxicity in multiple myeloma.
Intrabody against prolyl hydroxylase 2 ameliorates acetaminophen-induced acute liver injury in mice via concomitant promotion of angiogenesis and redox homeostasis.
A novel splice site indel alteration in the EIF2AK3 gene is responsible for the first cases of Wolcott-Rallison syndrome in Hungary.
A light-triggered self-reinforced nanoagent for targeted chemo-photodynamic therapy of breast cancer bone metastases via ER stress and mitochondria mediated apoptotic pathways.
Endoplasmic Reticulum Stress Signalling Induces Casein Kinase 1-Dependent Formation of Cytosolic TDP-43 Inclusions in Motor Neuron-Like Cells.
Iodine‑125 seed radiation induces ROS‑mediated apoptosis, autophagy and paraptosis in human esophageal squamous cell carcinoma cells.
Sulforaphane attenuates apoptosis of hippocampal neurons induced by high glucose via regulating endoplasmic reticulum.
Ubiquitin C-terminal hydrolase L1 (UCHL1) regulates post-myocardial infarction cardiac fibrosis through glucose-regulated protein of 78 kDa (GRP78).
UBE2T promotes glioblastoma invasion and migration via stabilizing GRP78 and regulating EMT.
Excretory/secretory products of Angiostrongylus cantonensis fifth-stage larvae induce endoplasmic reticulum stress via the Sonic hedgehog pathway in mouse astrocytes.
Perinatal low-dose PBDE-47 exposure hampered thyroglobulin turnover and induced thyroid cell apoptosis by triggering ER stress and lysosomal destabilization contributing to thyroid toxicity in adult female rats.
Polychlorinated Biphenyl Quinone Promotes Atherosclerosis through Lipid Accumulation and Endoplasmic Reticulum Stress via CD36.
Non-Esterified Fatty Acid-Induced Reactive Oxygen Species Mediated Granulosa Cells Apoptosis Is Regulated by Nrf2/p53 Signaling Pathway.
SHQ1 is an ER stress response gene that facilitates chemotherapeutics-induced apoptosis via sensitizing ER-stress response.
Circulating Exosomes From Lipopolysaccharide-Induced Ards Mice Trigger Endoplasmic Reticulum Stress in Lung Tissue.
Extracellular Vesicles Isolated from Human Induced Pluripotent Stem Cell-Derived Neurons Contain a Transcriptional Network.
Endosulfan induces endothelial inflammation and dysfunction via IRE1α/NF-κB signaling pathway.
78 kDa Glucose-Regulated Protein Attenuates Protein Aggregation and Monocyte Adhesion Induced by Angiotensin II in Vascular Cells.
Liraglutide protects pancreatic β cells from endoplasmic reticulum stress by upregulating MANF to promote autophagy turnover.
Withaferin A triggers G2/M arrest and intrinsic apoptosis in glioblastoma cells via ATF4-ATF3-CHOP axis.
Selenium Attenuates Chronic Heat Stress-Induced Apoptosis via the Inhibition of Endoplasmic Reticulum Stress in Mouse Granulosa Cells.
MCP-1 mediates ischemia-reperfusion-induced cardiomyocyte apoptosis via MCPIP1 and CaSR.
Hydrogen sulfide regulates muscle RING finger-1 protein S-sulfhydration at Cys(44) to prevent cardiac structural damage in diabetic cardiomyopathy.
Protective effect of Liraglutide on diabetic retinal neurodegeneration via inhibiting oxidative stress and endoplasmic reticulum stress.
Clinicopathological significance of endoplasmic reticulum stress proteins in ovarian carcinoma.
Oxidative Stress and Endoplasmic Reticulum Stress Are Involved in the Protective Effect of Alpha Lipoic Acid Against Heat Damage in Chicken Testes.
Protection of retinal function and morphology in MNU-induced retinitis pigmentosa rats by ALDH2: an in-vivo study.
Hepatic DNAJB9 Drives Anabolic Biasing to Reduce Steatosis and Obesity.
Fengbaisan suppresses endoplasmic reticulum stress by up-regulating SIRT1 expression to protect rats with chronic obstructive pulmonary diseases.
NLRP3 inflammasome and endoplasmic reticulum stress in the epileptogenic zone in temporal lobe epilepsy: molecular insights into their interdependence.
Zinc application alleviates the adverse renal effects of arsenic stress in a protein quality control way in common carp.
Exogenous hydrogen sulfide inhibits apoptosis by regulating endoplasmic reticulum stress-autophagy axis and improves myocardial reconstruction after acute myocardial infarction.
ALDH2 protects naturally aged mouse retina via inhibiting oxidative stress-related apoptosis and enhancing unfolded protein response in endoplasmic reticulum.
Cell cycle exit during bortezomib-induced osteogenic differentiation of mesenchymal stem cells was mediated by Xbp1s-upregulated p21(Cip1) and p27(Kip1).
Hydrogen sulphide ameliorating skeletal muscle atrophy in db/db mice via Muscle RING finger 1 S-sulfhydration.
Proteomic Analysis Reveals Proteins and Pathways Associated with Lactation in Bovine Mammary Epithelial Cell-Derived Exosomes.
FGF21 mitigates atherosclerosis via inhibition of NLRP3 inflammasome-mediated vascular endothelial cells pyroptosis.
LncRNA GUARDIN suppresses cellular senescence through a LRP130-PGC1α-FOXO4-p21-dependent signaling axis.
CACNA1H downregulation induces skeletal muscle atrophy involving endoplasmic reticulum stress activation and autophagy flux blockade.
Exosomes from mesenchymal stem cells modulate endoplasmic reticulum stress to protect against nucleus pulposus cell death and ameliorate intervertebral disc degeneration in vivo.
GRP78 regulates milk biosynthesis and the proliferation of bovinemammaryepithelial cells through the mTOR signaling pathway.
Unfolded Protein Response Pathways Correlatively Modulate Endoplasmic Reticulum Stress Responses in Rat Retinal Müller Cells.
Betulinic Acid Suppresses Breast Cancer Metastasis by Targeting GRP78-Mediated Glycolysis and ER Stress Apoptotic Pathway.
UFL1 Alleviates Lipopolysaccharide-Induced Cell Damage and Inflammation via Regulation of the TLR4/NF-κB Pathway in Bovine Mammary Epithelial Cells.
ZYZ-803 Mitigates Endoplasmic Reticulum Stress-Related Necroptosis after Acute Myocardial Infarction through Downregulating the RIP3-CaMKII Signaling Pathway.
Alpha-mangostin induces endoplasmic reticulum stress and autophagy which count against fatty acid synthase inhibition mediated apoptosis in human breast cancer cells.
The IRE1α-XBP1 pathway function in hypoxia-induced pulmonary vascular remodeling, is upregulated by quercetin, inhibits apoptosis and partially reverses the effect of quercetin in PASMCs.
Antimetastatic Effect of Fucoidan-Sargassum against Liver Cancer Cell Invadopodia Formation via Targeting Integrin αVβ3 and Mediating αVβ3/Src/E2F1 Signaling.
Abnormal Glucose Metabolism and Insulin Resistance Are Induced via the IRE1α/XBP-1 Pathway in Subclinical Hypothyroidism.
Vildagliptin Reduces Stenosis of Injured Carotid Artery in Diabetic Mouse Through Inhibiting Vascular Smooth Muscle Cell Proliferation via ER Stress/NF-κB Pathway.
Correction to: Protective effects of dioscin against alcohol‑induced liver injury.
Regulatory role of Golgi brefeldin A resistance factor-1 in amyloid precursor protein trafficking, cleavage and Aβ formation.
Mechanisms of IFNalpha-1a-Induced Apoptosis in a Laryngeal Cancer Cell Line.
BDE-209 induces autophagy and apoptosis via IRE1α/Akt/mTOR signaling pathway in human umbilical vein endothelial cells.
Resveratrol reduces brain injury after subarachnoid hemorrhage by inhibiting oxidative stress and endoplasmic reticulum stress.
Suhuang antitussive capsule inhibits NLRP3 inflammasome activation and ameliorates pulmonary dysfunction via suppression of endoplasmic reticulum stress in cough variant asthma.
Niban protein regulates apoptosis in HK-2 cells via caspase-dependent pathway.
Lopinavir-Ritonavir Combination Induces Endoplasmic Reticulum Stress and Kills Urological Cancer Cells.
Impaired calcium homeostasis via advanced glycation end products promotes apoptosis through endoplasmic reticulum stress in human nucleus pulposus cells and exacerbates intervertebral disc degeneration in rats.
Sevoflurane modulates AQPs (1,5) expression and endoplasmic reticulum stress in mice lung with allergic airway inflammation.
Inhibiting lysine 353 oxidation of GRP78 by a hypochlorous probe targeting endoplasmic reticulum promotes autophagy in cancer cells.
ER stress activation impairs the expression of circadian clock and clock-controlled genes in NIH3T3 cells via an ATF4-dependent mechanism.
Quantitative interaction proteomics reveals differences in the interactomes of amyloid precursor protein isoforms.
Flaccidoxide-13-Acetate-Induced Apoptosis in Human Bladder Cancer Cells is through Activation of p38/JNK, Mitochondrial Dysfunction, and Endoplasmic Reticulum Stress Regulated Pathway.
ERp29 counteracts the suppression of malignancy mediated by endoplasmic reticulum stress and promotes the metastasis of colorectal cancer.
High-fat diet induces aberrant hepatic lipid secretion in blunt snout bream by activating endoplasmic reticulum stress-associated IRE1/XBP1 pathway.
Pharmacological preconditioning with the cellular stress inducer thapsigargin protects against experimental sepsis.
Low-concentration HCP1 inhibits apoptosis in vascular endothelial cells.
Quantitative proteomic analysis of deer antler stem cells as a model of mammalian organ regeneration.
A Legionella pneumophila Kinase Phosphorylates the Hsp70 Chaperone Family to Inhibit Eukaryotic Protein Synthesis.
Cyclophilin B control of lysine post-translational modifications of skin type I collagen.
Exosomes from Microglia Attenuate Photoreceptor Injury and Neovascularization in an Animal Model of Retinopathy of Prematurity.
APS could potentially activate hepatic insulin signaling in HFD-induced IR mice.
Metformin induces TPC-1 cell apoptosis through endoplasmic reticulum stress-associated pathways in vitro and in vivo.
Knockdown of TM9SF4 boosts ER stress to trigger cell death of chemoresistant breast cancer cells.
Ranolazine prevents pressure overload-induced cardiac hypertrophy and heart failure by restoring aberrant Na(+) and Ca(2+) handling.
c‑Jun N‑terminal kinase/transforming growth factor‑β/Smad3 pathway: Is it associated with endoplasmic reticulum stress‑mediated renal interstitial fibrosis?
Paneth cell ablation increases the small intestinal injury during acute necrotizing pancreatitis in rats.
The deubiquitylase OTUD3 stabilizes GRP78 and promotes lung tumorigenesis.
Induction of Endoplasmic Reticulum Stress by Cadmium and Its Regulation on Nrf2 Signaling Pathway in Kidneys of Rats.
Co-downregulation of GRP78 and GRP94 Induces Apoptosis and Inhibits Migration in Prostate Cancer Cells.
Autophagy activation alleviates nonylphenol-induced apoptosis in cultured cortical neurons.
Pterostilbene exerts a protective effect via regulating tunicamycin-induced endoplasmic reticulum stress in mouse preimplantation embryos.
MiR-451a suppressing BAP31 can inhibit proliferation and increase apoptosis through inducing ER stress in colorectal cancer.
Mesencephalic astrocyte-derived neurotrophic factor (MANF) protects against Aβ toxicity via attenuating Aβ-induced endoplasmic reticulum stress.
Chronic intermittent hypoxia accelerates liver fibrosis in rats with combined hypoxia and nonalcoholic steatohepatitis via angiogenesis rather than endoplasmic reticulum stress.
Induction of the unfolded protein response (UPR) during pseudorabies virus infection.
Inhibition of CACNA1H attenuates doxorubicin-induced acute cardiotoxicity by affecting endoplasmic reticulum stress.
Signaling from mTOR to eIF2α mediates cell migration in response to the chemotherapeutic doxorubicin.
Human placenta-derived mesenchymal stem cells inhibit apoptosis of granulosa cells induced by IRE1α pathway in autoimmune POF mice.
Bone marrow mesenchymal stem cells could reduce the toxic effects of hexavalent chromium on the liver by decreasing endoplasmic reticulum stress-mediated apoptosis via SIRT1/HIF-1α signaling pathway in rats.
Proteomic analysis of retinal pigment epithelium cells after exposure to UVA radiation.
The IRE1 signaling pathway is involved in the protective effect of low-dose LPS on myocardial ischemia-reperfusion injury.
Protective effect of curcumin against irinotecan‑induced intestinal mucosal injury via attenuation of NF‑κB activation, oxidative stress and endoplasmic reticulum stress.
Prion Protein Protects Cancer Cells against Endoplasmic Reticulum Stress Induced Apoptosis.
Porcine Circovirus Type 2 Induces ORF3-Independent Mitochondrial Apoptosis via PERK Activation and Elevation of Cytosolic Calcium.
Differentially expressed genes of HepG2 cells treated with gecko polypeptide mixture.
Heme Induces Endoplasmic Reticulum Stress (HIER Stress) in Human Aortic Smooth Muscle Cells.
Salvianolic Acid A Attenuates Endoplasmic Reticulum Stress and Protects Against Cholestasis-Induced Liver Fibrosis via the SIRT1/HSF1 Pathway.
Impact of GADD34 on Apoptosis of Tonsillar Mononuclear Cells from IgA Nephropathy Patients by Regulating Eif2α Phosphorylation.
MnTMPyP inhibits paraquat-induced pulmonary epithelial-like cell injury by inhibiting oxidative stress.
Neuroprotective Effects of dl-3-n-Butylphthalide against Doxorubicin-Induced Neuroinflammation, Oxidative Stress, Endoplasmic Reticulum Stress, and Behavioral Changes.
Methane-Rich Saline Ameliorates Sepsis-Induced Acute Kidney Injury through Anti-Inflammation, Antioxidative, and Antiapoptosis Effects by Regulating Endoplasmic Reticulum Stress.
Palmitic Acid Downregulates Thyroglobulin (Tg), Sodium Iodide Symporter (NIS), and Thyroperoxidase (TPO) in Human Primary Thyrocytes: A Potential Mechanism by Which Lipotoxicity Affects Thyroid?
Proscillaridin A Promotes Oxidative Stress and ER Stress, Inhibits STAT3 Activation, and Induces Apoptosis in A549 Lung Adenocarcinoma Cells.
Glucagon-Like Peptide-1 Mediates the Protective Effect of the Dipeptidyl Peptidase IV Inhibitor on Renal Fibrosis via Reducing the Phenotypic Conversion of Renal Microvascular Cells in Monocrotaline-Treated Rats.
Vitamin C alters the amount of specific endoplasmic reticulum associated proteins involved in lipid metabolism in the liver of mice synthesizing a nonfunctional Werner syndrome (Wrn) mutant protein.
UBIAD1 protects against oxygen-glucose deprivation/reperfusion-induced multiple subcellular organelles injury through PI3K/AKT pathway in N2A cells.
Amyotrophic lateral sclerosis (ALS) and Alzheimer's disease (AD) are characterised by differential activation of ER stress pathways: focus on UPR target genes.
Ticagrelor protects against AngII-induced endothelial dysfunction by alleviating endoplasmic reticulum stress.
Selenoprotein S protects against adipocyte death through mediation of the IRE1α-sXBP1 pathway.
Phosphoglucomutase 1 inhibits hepatocellular carcinoma progression by regulating glucose trafficking.
GanDouLing combined with Penicillamine improves cerebrovascular injury via PERK/eIF2α/CHOP endoplasmic reticulum stress pathway in the mouse model of Wilson's disease.
Tetrachlorobenzoquinone-Induced Nrf2 Confers Neuron-like PC12 Cells Resistance to Endoplasmic Reticulum Stress via Regulating Glutathione Synthesis and Protein Thiol Homeostasis.
Botulinum toxin B suppresses the pressure ulcer formation in cutaneous ischemia-reperfusion injury mouse model: Possible regulation of oxidative and endoplasmic reticulum stress.
A Novel Cx50 Insert Mutation from a Chinese Congenital Cataract Family Impairs Its Cellular Membrane Localization and Function.
Autophagy is a major mechanism for the dual effects of curcumin on renal cell carcinoma cells.
Bcl-2 overexpression reduces cisplatin cytotoxicity by decreasing ER-mitochondrial Ca2+ signaling in SKOV3 cells.
Effects of sevoflurane pretreatment on the apoptosis of rat H9c2 cardiomyocytes and the expression of GRP78.
Epigallocatechin-3-gallate alleviates bladder overactivity in a rat model with metabolic syndrome and ovarian hormone deficiency through mitochondria apoptosis pathways.
Advanced oxidation protein products aggravate cardiac remodeling via cardiomyocyte apoptosis in chronic kidney disease.
Serum vitamin C levels modulate the lifespan and endoplasmic reticulum stress response pathways in mice synthesizing a nonfunctional mutant WRN protein.
TRPV6 protects ER stress-induced apoptosis via ATF6α-TRPV6-JNK pathway in human embryonic stem cell-derived cardiomyocytes.
ER-localized protein-Herpud1 is a new mediator of IL-4-induced macrophage polarization and migration.
PGK1 and GRP78 overexpression correlates with clinical significance and poor prognosis in Chinese endometrial cancer patients.
Brucella induces unfolded protein response and inflammatory response via GntR in alveolar macrophages.
Excessive ER stress and the resulting autophagic flux dysfunction contribute to fluoride-induced neurotoxicity.
Young plasma reverses age-dependent alterations in hepatic function through the restoration of autophagy.
Protective Effects of Olive Leaf Extract on Acrolein-Exacerbated Myocardial Infarction via an Endoplasmic Reticulum Stress Pathway.
Asiatic acid from Potentilla chinensis alleviates non-alcoholic fatty liver by regulating endoplasmic reticulum stress and lipid metabolism.
Hepatic Mitochondrial Defects in a Nonalcoholic Fatty Liver Disease Mouse Model Are Associated with Increased Degradation of Oxidative Phosphorylation Subunits.
Perigestational exposure to low doses of PBDE-47 induces excessive ER stress, defective autophagy and the resultant apoptosis contributing to maternal thyroid toxicity.
Mini-peptide RPL41 attenuated retinal neovascularization by inducing degradation of ATF4 in oxygen-induced retinopathy mice.
CHOP induces apoptosis by affecting brain iron metabolism in rats with subarachnoid hemorrhage.
Downregulation of reticulocalbin-1 differentially facilitates apoptosis and necroptosis in human prostate cancer cells.
Hepatic loss of Lissencephaly 1 (Lis1) induces fatty liver and accelerates liver tumorigenesis in mice.
Exogenous H(2)S restores ischemic post-conditioning-induced cardioprotection through inhibiting endoplasmic reticulum stress in the aged cardiomyocytes.
Hydrogen Gas Attenuates Myocardial Ischemia Reperfusion Injury Independent of Postconditioning in Rats by Attenuating Endoplasmic Reticulum Stress-Induced Autophagy.
Endoplasmic Reticulum Stress Is Involved in Cochlear Cell Apoptosis in a Cisplatin-Induced Ototoxicity Rat Model.
TBHQ Alleviated Endoplasmic Reticulum Stress-Apoptosis and Oxidative Stress by PERK-Nrf2 Crosstalk in Methamphetamine-Induced Chronic Pulmonary Toxicity.
Involvement of endoplasmic reticulum stress in formalin-induced pain is attenuated by 4-phenylbutyric acid.
GRP78 plays an integral role in tumor cell inflammation-related migration induced by M2 macrophages.
The meta and bioinformatics analysis of GRP78 expression in gastric cancer.
Inhibition of Endoplasmic Reticulum Stress Alleviates Lung Injury Induced by Brain Death.
CNPY2 is a key initiator of the PERK-CHOP pathway of the unfolded protein response.
Therapeutic effects of L-Cysteine in newborn mice subjected to hypoxia-ischemia brain injury via the CBS/H(2)S system: Role of oxidative stress and endoplasmic reticulum stress.
Thioredoxin is implicated in the anti‑apoptotic effects of grape seed proanthocyanidin extract during hyperglycemia.
Hepatitis B virus X protein inhibits apoptosis by modulating endoplasmic reticulum stress response.
PCSK9 regulates apoptosis in human lung adenocarcinoma A549 cells via endoplasmic reticulum stress and mitochondrial signaling pathways.
Renin-angiotensin system activation accelerates atherosclerosis in experimental renal failure by promoting endoplasmic reticulum stress-related inflammation.
Calcium release induced by 2-pyridinecarboxaldehyde thiosemicarbazone and its copper complex contributes to tumor cell death.
Identification of Novel SCIRR69-Interacting Proteins During ER Stress Using SILAC-Immunoprecipitation Quantitative Proteomics Approach.
Exogenous H(2)S regulates endoplasmic reticulum-mitochondria cross-talk to inhibit apoptotic pathways in STZ-induced type I diabetes.
Cr(VI) induces cytotoxicity in vitro through activation of ROS-mediated endoplasmic reticulum stress and mitochondrial dysfunction via the PI3K/Akt signaling pathway.
Curcumin enhances the effects of irinotecan on colorectal cancer cells through the generation of reactive oxygen species and activation of the endoplasmic reticulum stress pathway.
Cell surface GRP78 facilitates hepatoma cells proliferation and migration by activating IGF-IR.
Endoplasmic reticulum stress and apoptosis via PERK-eIF2α-CHOP signaling in the methamphetamine-induced chronic pulmonary injury.
GALNT6 Stabilizes GRP78 Protein by O-glycosylation and Enhances its Activity to Suppress Apoptosis Under Stress Condition.
Knockdown of histidine-rich calcium-binding protein (HRC) suppresses liver fibrosis by inhibiting the activation of hepatic stellate cells.
A positive feedback loop between GRP78 and VPS34 is critical for GRP78-mediated autophagy in cancer cells.
Protective effect of mesenchymal stem cells on the pressure ulcer formation by the regulation of oxidative and endoplasmic reticulum stress.
Elevated urinary CRELD2 is associated with endoplasmic reticulum stress-mediated kidney disease.
Autoantibodies against glucose-regulated protein 78 as serological biomarkers in metastatic and recurrent hepatocellular carcinoma.
Quantitative Proteomic Profiling the Molecular Signatures of Annexin A5 in Lung Squamous Carcinoma Cells.
A Health Threat to Bystanders Living in the Homes of Smokers: How Smoke Toxins Deposited on Surfaces Can Cause Insulin Resistance.
Dysfunctional tubular endoplasmic reticulum constitutes a pathological feature of Alzheimer's disease.
Activating Transcription Factor 4 (ATF4)-ATF3-C/EBP Homologous Protein (CHOP) Cascade Shows an Essential Role in the ER Stress-Induced Sensitization of Tetrachlorobenzoquinone-Challenged PC12 Cells to ROS-Mediated Apoptosis via Death Receptor 5 (DR5) Signaling.
Hydrogen-rich saline mediates neuroprotection through the regulation of endoplasmic reticulum stress and autophagy under hypoxia-ischemia neonatal brain injury in mice.
Design, purification and assessment of GRP78 binding peptide-linked Subunit A of Subtilase cytotoxic for targeting cancer cells.
Palmitic acid aggravates inflammation of pancreatic acinar cells by enhancing unfolded protein response induced CCAAT-enhancer-binding protein β-CCAAT-enhancer-binding protein α activation.
Chronic alpha-linolenic acid treatment alleviates age-associated neuropathology: Roles of PERK/eIF2α signaling pathway.
Rifampicin-induced injury in L02 cells is alleviated by 4-PBA via inhibition of the PERK-ATF4-CHOP pathway.
Cytotoxicity of 11-epi-Sinulariolide Acetate Isolated from Cultured Soft Corals on HA22T Cells through the Endoplasmic Reticulum Stress Pathway and Mitochondrial Dysfunction.
Alpha-lipoic acid defends homocysteine-induced endoplasmic reticulum and oxidative stress in HAECs.
Cyanidin 3-O-β-Glucoside Ameliorates Ethanol-Induced Acute Liver Injury by Attenuating Oxidative Stress and Apoptosis: The Role of SIRT1/FOXO1 Signaling.
Japanese encephalitis virus induces apoptosis by the IRE1/JNK pathway of ER stress response in BHK-21 cells.
Translation from the 5' untranslated region shapes the integrated stress response.
The ATF6 pathway of the ER stress response contributes to enhanced viability in glioblastoma.
Effects of Placental Ischemia Are Attenuated by 1,25-Dihydroxyvitamin D Treatment and Associated with Reduced Apoptosis and Increased Autophagy.
ABT737 reverses cisplatin resistance by regulating ER-mitochondria Ca2+ signal transduction in human ovarian cancer cells.
Resveratrol Induces Cancer Cell Apoptosis through MiR-326/PKM2-Mediated ER Stress and Mitochondrial Fission.
Cathelicidin PR-39 peptide inhibits hypoxia/reperfusion-induced kidney cell apoptosis by suppression of the endoplasmic reticulum-stress pathway.
Endoplasmic Reticulum Stress May Play a Pivotal Role in Lipid Metabolic Disorders in a Novel Mouse Model of Subclinical Hypothyroidism.
PACE4 regulates apoptosis in human prostate cancer cells via endoplasmic reticulum stress and mitochondrial signaling pathways.
Metabolic and Phenotypic Differences between Mice Producing a Werner Syndrome Helicase Mutant Protein and Wrn Null Mice.
Impaired unfolded protein response in the degeneration of cochlea cells in a mouse model of age-related hearing loss.
IRE1 prevents endoplasmic reticulum membrane permeabilization and cell death under pathological conditions.
Polychlorinated biphenyl quinone induces endoplasmic reticulum stress, unfolded protein response, and calcium release.
Legionella suppresses the host unfolded protein response via multiple mechanisms.
Knockdown of glucose-regulated protein 78/binding immunoglobulin heavy chain protein expression by asymmetric small interfering RNA induces apoptosis in prostate cancer cells and attenuates migratory capability.
Potent effects of the total saponins from Dioscorea nipponica Makino against streptozotocin-induced type 2 diabetes mellitus in rats.
Impact of vitamin C on the cardiometabolic and inflammatory profiles of mice lacking a functional Werner syndrome protein helicase.
Ketamine-induced ulcerative cystitis and bladder apoptosis involve oxidative stress mediated by mitochondria and the endoplasmic reticulum.
Protective effects of dioscin against alcohol-induced liver injury.
The resveratrol attenuates ethanol-induced hepatocyte apoptosis via inhibiting ER-related caspase-12 activation and PDE activity in vitro.
Exposure to tributyltin induces endoplasmic reticulum stress and the unfolded protein response in zebrafish.
ABCG1 deficiency promotes endothelial apoptosis by endoplasmic reticulum stress-dependent pathway.
Protein kinase RNA-like endoplasmic reticulum kinase (PERK) signaling pathway plays a major role in reactive oxygen species (ROS)-mediated endoplasmic reticulum stress-induced apoptosis in diabetic cardiomyopathy.
The alteration of protein profile induced by cigarette smoking via oxidative stress in mice epididymis.
Upregulation of phosphorylated HSP27, PRDX2, GRP75, GRP78 and GRP94 in acquired middle ear cholesteatoma growth.
Protective effects of the total saponins from Rosa laevigata Michx fruit against carbon tetrachloride-induced acute liver injury in mice.
Selenium deficiency is associated with endoplasmic reticulum stress in a rat model of cardiac malfunction.
Cell intrinsic role of COX-2 in pancreatic cancer development.
Profiling of differentially expressed proteins in stage IV colorectal cancers with good and poor outcomes.
Proteomic analysis of anti-tumor effects of 11-dehydrosinulariolide on CAL-27 cells.
Co-chaperone HSJ1a dually regulates the proteasomal degradation of ataxin-3.
Lei Y, Chen Y, Pan Y
Folia morphologica 2026;85:e01726044
Folia morphologica 2026;85:e01726044
After Traumatic Brain Injury, EPHA4 Enhances Endoplasmic Reticulum Stress to Promote M1 Microglial Polarization Through the MAPK Signaling Pathway.
Tan Y, Xia J, Liu M, Deng S, Wu H, Qian C
Mediators of inflammation 2026;2026:5595023
Mediators of inflammation 2026;2026:5595023
Electroacupuncture reduces calcium influx and inhibits endoplasmic reticulum stress by inhibiting the PKCδ-TRPA1 pathway to promote motor function recovery after spinal cord injury.
Zhang Y, Liang C, Huang Z, Hu Y, Mo Y, Ning S, Li Z, Wu Y, Zhang J, Li X, Wang Z
Burns & trauma 2026;14:tkaf066
Burns & trauma 2026;14:tkaf066
RNF26 regulating tumor immunogenicity of hepatocellular carcinoma by degrading GRP78 and instigating ER stress.
Luo J, Zhuo H, Zheng M, Fang Y, Wang X, Jin Y, Li Y, Du S, Wang J, Xue C, Jiang R, Li G
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2026 May;86:101375
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2026 May;86:101375
Nur77 attenuates Paneth cell necroptosis-induced intestinal inflammation through regulating endoplasmic reticulum homeostasis in sepsis.
Cui C, Huo Q, Ran S, Wang W, Wei H, Peng J
Journal of advanced research 2026 May;83:269-285
Journal of advanced research 2026 May;83:269-285
PRAS40 activates the IRE1α-XBP-1-mediated unfolded protein response to exacerbate colorectal cancer by enhancing ST6Gal1-dependent α-2, 6 sialylation of GRP78.
Teng H, Guo Y, Chen X, Fan A, Zhang C, Zhang T, Luo Y, Huang L
Neoplasia (New York, N.Y.) 2026 May;75:101297
Neoplasia (New York, N.Y.) 2026 May;75:101297
ATF3 links endoplasmic reticulum stress to ferroptosis via transcriptional activation of ALOX12 in benzene-induced hematotoxicity.
Zeng H, Li Y, Zhao H, Chen L, Xu L, Wang S, Zhang Y, Wang H, Huang S, Xu Y, You C, Sun L, Cui F, Tang H
Ecotoxicology and environmental safety 2026 May;316:120130
Ecotoxicology and environmental safety 2026 May;316:120130
SIRT3 promotes oxaliplatin sensitivity in hepatocellular carcinoma by promoting ferroptosis through endoplasmic reticulum stress response.
Xu Y, Ma C, Xu X, Tu J, Chen X, Yang X, Sun D, Liu S, Wan Y, Qin L, Gu W, Qian H
Pathology, research and practice 2026 May;281:156400
Pathology, research and practice 2026 May;281:156400
Increased FICD-mediated protein AMPylation triggers conserved endoplasmic reticulum stress signaling across species.
Hernandez-Lima MA, Mariner BL, Giblin W, McCormick MA, Truttmann MC
Cell stress & chaperones 2026 Mar;31(2):100149
Cell stress & chaperones 2026 Mar;31(2):100149
The sphingolipid metabolite sphingosine protects against hypertension by targeting metabolic-inflammatory crosstalk via the NLRP3 inflammasome.
Li W, Zhou D, Ji Y, Yang M, Yang Y, Dao M, He X, Jin X
International journal of cardiology. Cardiovascular risk and prevention 2026 Mar;28:200562
International journal of cardiology. Cardiovascular risk and prevention 2026 Mar;28:200562
ENDOU-1-induced cytoplasmic HnRNPA3 recognizes m6A methylation on the upstream reading frame of human CHOP transcripts to achieve maximal CHOP translation.
Lee HC, Huang YH, Hsieh CC, Ke YN, Tsai HJ
Cellular and molecular life sciences : CMLS 2026 Mar 28;83(1)
Cellular and molecular life sciences : CMLS 2026 Mar 28;83(1)
Investigating PKD2 deficiency-associated cardiomyopathies using hESC-cardiomyocytes and bioengineered 3D ventricular cardiac tissue strips.
Li J, Peng W, Kwok M, Ding H, Zhuo D, Gurung B, Lakhani IR, Yu H, Poon EN, Li RA, Yao X
Cell death & disease 2026 Mar 25;17(1)
Cell death & disease 2026 Mar 25;17(1)
Ferulic Acid Alleviates Chemotherapy-Induced POI by Targeting the Grp78 and Perk-eIF2α-ATF4-CHOP Pathway to Attenuate Endoplasmic Reticulum Stress.
Li F, Huang Y, Liu Z, Geng Y, Hu R, Song Y, Xu L, Zhang M
Biomedicines 2026 Mar 19;14(3)
Biomedicines 2026 Mar 19;14(3)
Modulating GRP75 to restore calcium homeostasis: a novel neuroprotective strategy of CRSE6(#) in Parkinson's disease models.
Wang X, Li S, Xiang X, Zhang X, Yu C, Qing D, Law BY, Tang Y
Journal of advanced research 2026 Mar 19;
Journal of advanced research 2026 Mar 19;
LCN2 aggravates sepsis-induced ALI by inhibiting MUC1 to activate ER-stress-autophagy induced ferroptosis via lactate/MCT1/AMPK/mTOR axis.
Chen SX, Qi X, Zheng XT, Bi ZM, Zhang Y, Wang YM
Apoptosis : an international journal on programmed cell death 2026 Mar 15;31(3)
Apoptosis : an international journal on programmed cell death 2026 Mar 15;31(3)
African swine fever virus MGF_110-8L promotes host cell autophagy and suppresses interferon signaling by activating the unfolded protein response.
Hou YP, Yang JK, Wang Y, Xia T, Wu X
Veterinary microbiology 2026 Jun;317:111013
Veterinary microbiology 2026 Jun;317:111013
Truncated N-glycans destabilize POMT1 and POMT2 but do not limit cellular O-mannosylation in HEK293 cells.
Sturm D, Hölscher C, Martínez IA, Harst A, Konstantinidi A, Alam S, Burock R, Vakhrushev SY, Hoffmann M, Ruppert T, Rapp E, Halim A, Thiel C, Strahl S
Molecular genetics and metabolism 2026 Jun;148(2):110115
Molecular genetics and metabolism 2026 Jun;148(2):110115
Leveraging ANXA1 to enhance recombinant protein yields in CHO cells: A UPR-Mediated bioprocessing approach.
Zhao Q, Zhang HJ, Han MM, Abiti J, Dong YJ, Wang JN, Lu JT, Wang W, Zhang X, Geng SL, Qiu LL, Wang XY, Hua ZC, Wang TY, Jia YL
Synthetic and systems biotechnology 2026 Jun;12:197-208
Synthetic and systems biotechnology 2026 Jun;12:197-208
Tetramethylpyrazine mitigates ER-stress-driven ATF4/CHOP apoptosis to protect dopaminergic neurons in cellular and MPTP models of Parkinson's disease.
Zhan S, Wen S, Wu L, Zhang X, Liu J, Zhang G, Liu H
Neuropharmacology 2026 Jun 1;290:110899
Neuropharmacology 2026 Jun 1;290:110899
CAMKMT knockdown delays myopia progression by reducing calcium Ion-mediated ER Stress-induced apoptosis.
Hao J, Ma Z, Yang Z, Zhang R, Zhang Y, Yin X, Liu J, Bao B, Liao X, Bi H, Guo D
Methods (San Diego, Calif.) 2026 Jul;251:126-137
Methods (San Diego, Calif.) 2026 Jul;251:126-137
PDIA6 as a novel pharmacological target for metabolic dysfunction-associated steatohepatitis via alleviating endoplasmic reticulum stress.
Hu H, Liao J, Yang S, Li W, Feng S, Zhang Y, Lin Q, Huang J, He W, Liu D, Gao L, Zhang Q, Luo P, Wang J
Free radical biology & medicine 2026 Jul;250:258-273
Free radical biology & medicine 2026 Jul;250:258-273
Single-cell transcriptomic atlas of shrimp hepatopancreas reveals an endoplasmic reticulum stress-dependent immune response to Vibrio parahaemolyticus infection.
Lu L, Lei Y, Ao C, Wan B, Li Q, Wang W
Fish & shellfish immunology 2026 Jul;174:111364
Fish & shellfish immunology 2026 Jul;174:111364
The lamin A/C-P4HB interaction axis regulates endoplasmic reticulum stress and apoptosis in myocardial ischemia-reperfusion injury via a calreticulin-associated mechanism.
Zhou J, Li X, Li N, Wang M, Sun G
Cellular signalling 2026 Jul;143:112479
Cellular signalling 2026 Jul;143:112479
LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells.
Hou X, Wang Y, Chen Y, Zhong P, Wang G, Li B, Lu B, Jiang H, Ning S
Oncology reports 2026 Jan;55(1)
Oncology reports 2026 Jan;55(1)
Sennoside A ameliorates cognitive impairment by inhibiting USP14/ERK1/2 pathway in a mouse model of type 2 diabetes mellitus.
Wang L, He ZQ, Xu ZY, Qi YK, Sun YN
Behavioural brain research 2026 Jan 5;496:115853
Behavioural brain research 2026 Jan 5;496:115853
SRSF3 promotes the generation of XBP1s to stabilize autophagy and enhance hypoxia adaptation in glioma.
Liu B, Zhang X, Tian J, Huang X, Li X, Zhao J, Xu Z, Pu J
European journal of histochemistry : EJH 2026 Jan 26;70(1)
European journal of histochemistry : EJH 2026 Jan 26;70(1)
Differential Toxicity of Water-Soluble Versus Water-Insoluble Components of Cowshed PM2.5 on Ovarian Granulosa Cells and the Regulatory Role of Txnip in Overall Toxicity.
Ma Z, Zhang X, Du X, Zhao C, Jia Y, Wang Y, Li X, Yu X, Gao Y
Antioxidants (Basel, Switzerland) 2026 Jan 21;15(1)
Antioxidants (Basel, Switzerland) 2026 Jan 21;15(1)
Ginseng Polysaccharides Protect Against Endoplasmic Reticulum Stress-Induced Damage via PI3K/Akt Signalling Pathway in Bovine Ovarian Granulosa Cells.
Wang H, Fang Y, Huang L, Yang X, Ma X, Lyu Y, Jing G, Ding H, Liu H, Lyu W
Cells 2026 Jan 17;15(2)
Cells 2026 Jan 17;15(2)
Quantitative proteomic analysis identifies the unfolded protein response as a host pathway co-opted by ASFV to promote replication.
Zhang D, Liu B, Liu H, Mao R, Cao W, Zhang X, Yang F, Wang Y, Shen C, Zhang S, Zhu Z, Zheng H
mBio 2026 Jan 14;17(1):e0324225
mBio 2026 Jan 14;17(1):e0324225
Detection of factors related to ROS and ERS in the reproductive organs of hibernating Daurian ground squirrels (Spermophilus dauricus)†.
Wang MD, Dong JY, Chen L, Li LF, Xi YF, Wang JC, Hu LJ, Xu JH, Wang Z
Biology of reproduction 2026 Jan 11;114(1):310-324
Biology of reproduction 2026 Jan 11;114(1):310-324
AhR/ROS-mediated endoplasmic reticulum stress contributes to PFOSA-induced cardiac defects.
Wang K, Chen H, Chen P, Wu L, Jiang Y, Chen T
Toxicology 2026 Feb;520:154363
Toxicology 2026 Feb;520:154363
GNB2 promotes breast cancer progression by up-regulating HSPA5/GPX4 and inhibiting ferroptosis.
Wang Y, Liu R, Tian C, Kang Z, Xu Z, Wang Z, Xu S, Zhong J
Molecular and cellular biochemistry 2026 Feb;481(2):871-884
Molecular and cellular biochemistry 2026 Feb;481(2):871-884
Helicobacter mastomyrinus Cytolethal Distending Toxin Induces Calcium Dyshomeostasis and Liver Injury via Endoplasmic Reticulum Stress.
Bao R, Jin S, Zhuang T, Hu M, Yang L, Wang T, Zhu L, Zhang Q
Annals of the New York Academy of Sciences 2026 Feb;1556(1):e70159
Annals of the New York Academy of Sciences 2026 Feb;1556(1):e70159
HSPA5 promotes YAP/TAZ stability independently of the Hippo pathway and induces proneural-to-mesenchymal transition in glioblastoma.
Gui S, Yu W, Song Z, Peng L, Luo H, Huang K, Xiao J, Xie J, Cai S, Yuan S, Tao Z, Cheng Z
Cell death & disease 2026 Feb 7;17(1):208
Cell death & disease 2026 Feb 7;17(1):208
Mazdutide Ameliorates Metabolic Dysfunction-Associated Steatotic Liver Disease by Modulating Endoplasmic Reticulum Stress, Improving Lipid Metabolism and Alleviating Inflammation.
Gan L, Duan L, Zheng X
Pharmaceuticals (Basel, Switzerland) 2026 Feb 26;19(3)
Pharmaceuticals (Basel, Switzerland) 2026 Feb 26;19(3)
Inhibiting HSP27 activates the XBP1s/CerS1 interplay, which triggers DRP1-driven mitophagy, thereby protecting against cell death and promoting the KSHV lytic cycle in primary effusion lymphoma cells.
Gonnella R, Corrado V, Scaffidi GF, Benedetti R, Di Crosta M, Zarrella R, Gilardini Montani MS, Santarelli R, Cirone M
Cell death discovery 2026 Feb 26;12(1)
Cell death discovery 2026 Feb 26;12(1)
NEAT1 drives SARS-CoV-2 N protein-induced inflammation, metabolic reprogramming, and mitochondria-ER stress crosstalk.
Qing C, Chen H, Huang S, Zhang J, Zhou C, Zhang S, Luo K, Wang C, Hu Z, Yang Y, Zhou J, Zeng Z
Scientific reports 2026 Feb 25;16(1)
Scientific reports 2026 Feb 25;16(1)
Role of Sigma-1 Receptors in the Paraventricular Nucleus and Myocardium during Cirrhotic Cardiomyopathy in Rats.
Yu A, Li Y, Li J, Deng S
Molecular neurobiology 2026 Feb 21;63(1)
Molecular neurobiology 2026 Feb 21;63(1)
VAMP7-dependent late endosomal secretion of ER and mitochondrial proteins impacts the tumor microenvironment and macrophage engagement.
Vats S, Dionisio P, Lemercier Q, Pineau R, Therreau L, Lipecka J, Cholley B, Moog JB, Wojnacki J, Keime C, Zala D, Bun P, Freire S, Domingues N, Danglot L, Guerrera IC, Delevoye C, Chevet E, Raimundo N, Galli T
Nature communications 2026 Feb 21;17(1)
Nature communications 2026 Feb 21;17(1)
LncRNA SLC16A1-AS1 cooperates with NSUN2 to stabilize GRP78 mRNA via m5C modification in gastric cancer.
Zheng B, Zhao W, Jin Y, Sun W, Li Y, Zhang Q, Li Y, Wang J, Chen D, Ren K, Zhang W, Chen Y, Yuan L, Wang XJ, Yang F, Chen J
iScience 2026 Feb 20;29(2):114614
iScience 2026 Feb 20;29(2):114614
TAZ (Wwtr1) deficiency leads to ER stress and mitochondrial dysfunction in a mouse model of Fuchs' endothelial corneal dystrophy.
Park S, Ramarapu R, Lim J, Khan S, Khan MJ, Stoehr WR, Leonard BC, Thomasy SM
bioRxiv : the preprint server for biology 2026 Feb 19;
bioRxiv : the preprint server for biology 2026 Feb 19;
CLCC1 governs ER bilayer equilibration to maintain lipid homeostasis.
Wu L, Wang J, Wang Y, Yang J, Yao Y, Wang Y, Huang D, Hu Y, Xu X, Wang R, Du W, Shi Y, Li Q, Liu L, Zhu Y, Li S, Chen FJ, Zhang X, Wang X, Guo Q, Xu L, Li P, Chen XW
Nature 2026 Apr;652(8109):471-480
Nature 2026 Apr;652(8109):471-480
Brucella Omp25 activates the unfolded protein response to promote intracellular proliferation and inflammation.
Yang JK, Huang S, Hou YP, Yuan HF, Wang Y, Li M, Cao LB, Xia T, Shu HB, Wu X
The Journal of biological chemistry 2026 Apr;302(4):111333
The Journal of biological chemistry 2026 Apr;302(4):111333
Tetrastigma Hemsleyanum Polysaccharide Suppresses Triple-Negative Breast Cancer by Disrupting the Hippo-YAP/TEAD4-PDIA4 Axis and Endoplasmic Reticulum Stress Adaptation.
Shang Y, Si W, Zhang Y, Liu J, Zhang H, Li Y, Su H, Jiang W, Ding Z, Wang L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr 2;:e19006
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr 2;:e19006
Advanced oxidation protein products exacerbate osteoarthritis progression by disrupting stress granules assembly via endoplasmic reticulum stress.
Jiang W, Wang Q, Zhang X, Qi B, Liang Y, Li D, Yi C
Free radical biology & medicine 2026 Apr 18;251:440-453
Free radical biology & medicine 2026 Apr 18;251:440-453
Cardiac and brain pathological alterations with potential biomarker screening in stress-related fatalities.
Cong J, Wang L, Wang Y, Ji X, Xin H, Cong L, Zhang G, Zhu W, Cong B, Shi W
Journal of forensic and legal medicine 2026 Apr 16;120:103132
Journal of forensic and legal medicine 2026 Apr 16;120:103132
Qizhi Kebitong Formula Ameliorates Sciatic Nerve Injury in Streptozocin-induced Diabetic Mice through PERK/ATF4/CHOP Endoplasmic Reticulum Stress Signaling Pathway.
Yu H, Yang C, Wang G, Lv J, Li X, Qi W, Wang X
Current pharmaceutical design 2025;31(29):2370-2384
Current pharmaceutical design 2025;31(29):2370-2384
Decoding Endoplasmic Reticulum Stress on Chondrocyte Driving Osteoarthritis Development through Integrating Single-Cell and Transcriptomic Profiling.
Zhang Z, Cheng D, Dang J, Wang X, Fan H, Liu D
International journal of medical sciences 2025;22(15):3906-3923
International journal of medical sciences 2025;22(15):3906-3923
FKBP10 Promotes the Muscle Invasion of Bladder Cancer via Lamin A Dysregulation.
Zhao X, Wang J, Tian S, Tang L, Cao S, Ye J, Cai T, Xuan Y, Zhang X, Li X, Li H
International journal of biological sciences 2025;21(2):758-771
International journal of biological sciences 2025;21(2):758-771
The lncRNA SENCR knockdown alleviates vascular calcification via miR-4731-5p by suppressing endoplasmic reticulum stress.
Huang Y, Zhan W, Song C, Tan M, Wu L, Wu S
PloS one 2025;20(5):e0323058
PloS one 2025;20(5):e0323058
Thyroid Stimulating Hormone May Facilitates Adipose Tissue Insulin Resistance by Inducing M1 Macrophage Polarization.
Fu M, Wang H, Zhang Y, Yang L, Chen Y, Chen X, Wang Z, Sun H
Journal of inflammation research 2025;18:8331-8343
Journal of inflammation research 2025;18:8331-8343
Huanglian Jiedu Decoction Alleviates Myocardial Ischemia-Reperfusion Injury via AKT-Mediated Regulation of Endoplasmic Reticulum Stress.
Gu M, Xu J, Liao Z, Lin J, Li R, Wu W, Qiu Y
Journal of inflammation research 2025;18:17025-17044
Journal of inflammation research 2025;18:17025-17044
Volatile Oil From Acorus Gramineus Rhizoma Synergizes with Crebanine to Alleviate Oxidative Stress and Endoplasmic Reticulum Stress in Myocardial Ischemia-Reperfusion Injury by Suppressing GRP78-PERK/ATF6-CHOP and MAPK-NF-κB-TNF-α Signaling Pathways.
Zha L, Cui L, Mei J, Pu J, Hao J, Fan X, Wang H, Fang H, Ma Y
Journal of inflammation research 2025;18:12929-12948
Journal of inflammation research 2025;18:12929-12948
Liangfang Wenjing decoction regulates endoplasmic reticulum stress-mediated apoptosis to alleviate uterine microvascular injury in cold-stressed rats.
Lv T, Hu Y, Ma X, Feng L, Wang D, Song X, Xue S, Lu S, Cheng X
Frontiers in pharmacology 2025;16:1649924
Frontiers in pharmacology 2025;16:1649924
Targeting the self-amplifying loop between ATF6 and SNAI1 to inhibit epithelial‒mesenchymal transition in fibrotic lesions.
Wu T, Liu Y, Ma J, Lu L, Wang L, He M, Hao Z, Liu X, Zhang L, Zhao C, Tao M, Zheng C, Zhou J
Theranostics 2025;15(16):7940-7955
Theranostics 2025;15(16):7940-7955
Screening and identification of protein interacting with goose astrovirus.
Qian L, Liu Y, Wang X, Yang S, Ji L, Sun X, Wang J, Shan T, Zhang W, Shen Q
Frontiers in cellular and infection microbiology 2025;15:1595736
Frontiers in cellular and infection microbiology 2025;15:1595736
Impaired stemness in aging periodontal ligament stem cells is mediated by the progerin/endoplasmic reticulum stress/p53 axis.
Zhang X, Wang Y, Wang J, Zhang Y, Li R, Wang X, Ge X, Ye Q, Ji J, Fei D, Wang Q
Journal of advanced research 2025 Sep;75:377-388
Journal of advanced research 2025 Sep;75:377-388
Dimethyloxalylglycine improves functional recovery through inhibiting cell apoptosis and enhancing blood-spinal cord barrier repair after spinal cord injury.
Han W, Ding CC, Wei J, Dai DD, Wang N, Ren JM, Chen HL, Xie L
Chinese journal of traumatology = Zhonghua chuang shang za zhi 2025 Sep;28(5):361-369
Chinese journal of traumatology = Zhonghua chuang shang za zhi 2025 Sep;28(5):361-369
Quercetin diminishes scleral ER stress and protein misfolding: High throughput transcriptome analysis in form-deprivation myopia of Guinea pigs.
Lv L, Che D, Zhang Z, Zhang W, Zhou Q, Li F, Zhou J
Experimental eye research 2025 Sep;258:110485
Experimental eye research 2025 Sep;258:110485
Zinc Transporter 9 (ZnT9) Improves Obesity-Induced Asthenospermia by Attenuating Endoplasmic Reticulum Stress (ERS).
Liang C, Chen M, Mu Z, Tian X, Zhao W, Hu Y, Su J
Biological trace element research 2025 Sep;203(9):4648-4658
Biological trace element research 2025 Sep;203(9):4648-4658
hsa_circ_0004771-Targeted Adsorption of miR-429 Mediates ATP2A2 Expression to Attenuate Endoplasmic Reticulum Stress and Mitochondrial Dysfunction During Myocardial Infarction.
Deng Y, Wu Y, Liu S, Hou Y
Applied biochemistry and biotechnology 2025 Sep;197(9):6095-6119
Applied biochemistry and biotechnology 2025 Sep;197(9):6095-6119
Catestatin attenuates cerebral ischemia/reperfusion injury and suppresses endoplasmic reticulum stress.
Zhang X, Fan J, Ma S, Zhang N, Shi K, Chen M, Duan M, Yao Q, Cheng Y, Du S, Qu H, Yang H, Gao T, Zhan S
Neuropeptides 2025 Sep;113:102550
Neuropeptides 2025 Sep;113:102550
Propylparaben disrupts early embryonic development by causing oxidative stress-induced organelle dysfunction and actin zipper abnormality.
Pan ZN, Zhuang LL, Zhao HS, Yin SY, Chu M, Liu XY, Bao HC
Toxicology and applied pharmacology 2025 Sep 27;505:117581
Toxicology and applied pharmacology 2025 Sep 27;505:117581
PMAIP1 mediates endoplasmic reticulum stress in human dental pulp stem cells during pulpitis pathogenesis.
Zhou C, Zhang J, Chen L, Yu Y, Sun Y, Pan Y, Cai S, Zhong P
BMC oral health 2025 Sep 26;25(1):1472
BMC oral health 2025 Sep 26;25(1):1472
Mechanistic insights into fluoride-induced reproductive toxicity in female ovine animals: Mitochondrial dysfunction and ER stress-driven apoptosis in ovine granulosa cells.
Ma T, Jiang D, Liu W, Li Z, Gao K, Zhang Y
Ecotoxicology and environmental safety 2025 Sep 15;303:118830
Ecotoxicology and environmental safety 2025 Sep 15;303:118830
Nickel exposure induced endoplasmic reticulum stress by disturbing calcium homeostasis and triggered mitochondrial autophagy in domestic animal oocytes.
Zhong C, Hou S, Guo J, Zhao J, Wang J, Fang Y, Liu H, Ding H, Ma X, Lyu W
Ecotoxicology and environmental safety 2025 Sep 1;302:118668
Ecotoxicology and environmental safety 2025 Sep 1;302:118668
Protective role of RGS2 in PM2.5-induced ovarian injury in rats: Modulation of Gq/11 signaling to maintain granulosa cell [Ca(2 +) ]i stability.
Ma Z, Du X, Zhao C, Sun Y, Jia Y, Liang X, Yu X, Gao Y
Ecotoxicology and environmental safety 2025 Sep 1;302:118537
Ecotoxicology and environmental safety 2025 Sep 1;302:118537
Investigation of the effects of umbilical cord and adipose-derived mesenchymal stem cells on endoplasmic reticulum stress in cadmium-induced rat kidney.
Kartal B, Saçik U, Erbil G
Advances in medical sciences 2025 Oct;70(2):284-290
Advances in medical sciences 2025 Oct;70(2):284-290
cZFP609 Tethering BiP Alleviates Cartilage Degradation in Osteoarthritis via Remedying Aberrant ER-Mitochondrial Contacts.
Song Y, Luo JL, Zhang F, Shi J, Du S, Jiang HB, Zhang WD, Chen SY, Zhang DD, Kong P, Gao Y, Han M, Li H
MedComm 2025 Oct;6(10):e70405
MedComm 2025 Oct;6(10):e70405
Baicalin inhibits LPS-induced apoptosis and inflammation in WI- 38 cells by promoting FOXA2/TRIM27 Interaction: Implications for pediatric pneumonia mechanisms.
Gao L, Zeng X, Huang Y, Huang L
Naunyn-Schmiedeberg's archives of pharmacology 2025 Oct;398(10):14131-14142
Naunyn-Schmiedeberg's archives of pharmacology 2025 Oct;398(10):14131-14142
Quercetin induces immunogenic cell death against gastric cancer by targeting NR3C1.
Liu T, Wang Y, Peng M, Qi F, Liu Y, Ding H, Chen F
Toxicon : official journal of the International Society on Toxinology 2025 Oct;265:108477
Toxicon : official journal of the International Society on Toxinology 2025 Oct;265:108477
Perfluorohexane sulfonate (PFHxS) induces liver cytotoxicity by activating autophagy and endoplasmic reticulum stress-regulated mitochondrial pathway apoptosis.
Chen W, Liu S, Zhou Y, Liu B, Wang W, Chen C, Lou Z, Shen XL
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Oct;204:115657
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Oct;204:115657
Activation of Lysosomal Retrograde Transport Triggers TPC1-IP3R1 Ca(2+) Crosstalk at Lysosome-ER MCSs Leading to Lethal Depleting of ER Calcium.
Zhu MY, Guo YJ, Zhu YQ, Wang HZ, Wang HD, Chen HY, Jiang YX, Li H, Hui H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(39):e15313
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(39):e15313
Intestinal Epithelial-Derived USP13 Alleviates Colonic Inflammation by Suppressing GRP78-mediated Endoplasmic Reticulum Stress.
Qian C, Hu C, Xu Y, Xu W, Wang Z, Gan W, Tang W, Huang L, Samorodov AV, Wang Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(38):e00741
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(38):e00741
Legionella pneumophila Effector Protein LegU1 Mediates the Ubiquitination of Endoplasmic Reticulum Chaperone BiP.
Zhao B, He S, Huang M, Lu Y, Ge Z
Journal of microbiology and biotechnology 2025 Oct 28;35:e2507056
Journal of microbiology and biotechnology 2025 Oct 28;35:e2507056
Endoplasmic reticulum-resident protein DNAJC10 inhibits glioblastoma metastasis by suppressing XBP-1s-driven EGFR transcription.
Zhao E, Yu Y, Gao Y, Li T, Hao S, Chen M, Xu M, Arjun S, Yang C, Yin Y, Li M
Molecular biomedicine 2025 Oct 24;6(1):84
Molecular biomedicine 2025 Oct 24;6(1):84
DNAJC5 promotes cisplatin resistance in epithelial ovarian cancer by autophagy induced by the BiP/IRE1α/XBP1 endoplasmic reticulum stress pathway.
Huang S, Chen L, Chen Y, Lu S, Yang B, Chen Y, Zhao W, Zhao S
Scientific reports 2025 Oct 2;15(1):34323
Scientific reports 2025 Oct 2;15(1):34323
Changes of N(6)-methyladenosine modification and unfolded protein response in renal cell injury induced by cadmium.
Wang N, Dai J, Li R, Li W, Liu D, Liu X, Mei Z, Lu H, He Z, Gu S
Ecotoxicology and environmental safety 2025 Oct 15;305:119228
Ecotoxicology and environmental safety 2025 Oct 15;305:119228
Tumor-resident probiotic Clostridium butyricum improves aPD-1 efficacy in colorectal cancer models by inhibiting IL-6-mediated immunosuppression.
Xie M, Yuan K, Zhang Y, Zhang Y, Zhang R, Gao J, Wei W, Jiang L, Li T, Ding Y, Wang L, Lin Y, Wong CC, Yu J
Cancer cell 2025 Oct 13;43(10):1885-1901.e10
Cancer cell 2025 Oct 13;43(10):1885-1901.e10
Malate targets pyruvate kinase M2 to promote colorectal cancer cell cycle arrest and tumor suppression.
Zhao K, Zhang F, Qin Q, Zhang D, Yang F, Huang Y, Deng R, Jing H, Xiao W, Miao H, Shi R
Molecular biomedicine 2025 Oct 11;6(1):79
Molecular biomedicine 2025 Oct 11;6(1):79
Hypericin photoactivation induces triple-negative breast cancer cells pyroptosis by targeting the ROS/CALR/Caspase-3/GSDME pathway.
Liang C, Liu X, Yu J, Shi L, Wei W, Zhu Y, Feng M, Tang T, Li D, Yang T, Zheng J, Ma B, Wei L
Journal of advanced research 2025 Nov;77:669-688
Journal of advanced research 2025 Nov;77:669-688
Aerobic Exercise Training Exerts Neuroprotective Effects in Alzheimer's Disease Mice by Regulating Endoplasmic Reticulum Stress-Autophagy Pathway-Mediated Pyroptosis.
Wang Y, Sun X, He B, Yu S, Yu Y
CNS neuroscience & therapeutics 2025 Nov;31(11):e70620
CNS neuroscience & therapeutics 2025 Nov;31(11):e70620
Astragalin induces immunogenic cell death in liver cancer by targeting NQO2 to promote ROS-mediated endoplasmic reticulum stress pathway.
Zheng L, Zhao Z, Chen L, Yang W, Ercolani G, Qin P, Lin B, Han M, Weng Q, Zhang Y, Wu B, Chen M, Yao Z, Fang S, Ji J
Free radical biology & medicine 2025 Nov;239:317-335
Free radical biology & medicine 2025 Nov;239:317-335
Hydrogen sulfide alleviates vascular smooth muscle cell senescence by inhibiting endoplasmic reticulum stress.
Jiao L, Yan Q, Yang J, Wu R, Wei Z, Ruan J, Yan G, Chen X, Li H
Cellular signalling 2025 Nov;135:112075
Cellular signalling 2025 Nov;135:112075
Regulatory role of sirtuin-1 by targeting MDM2 to mitochondria-associated membranes formation in the treatment of NAFLD.
Zhang R, Zhang Q, Cui Z, Huang B, Li M, Ma H
Cell communication and signaling : CCS 2025 Nov 28;23(1):514
Cell communication and signaling : CCS 2025 Nov 28;23(1):514
RNF186 controls glucose metabolism in metabolic dysfunction-associated fatty liver disease.
Du J, Du Q, Zhang Y, Gao J, Wang C, Kou B, Jiang Y, Zhao D, Lin J
Cell & bioscience 2025 Nov 28;15(1):164
Cell & bioscience 2025 Nov 28;15(1):164
Thymoquinone inhibited the chondrogenic differentiation of tendon-derived stem cells caused by tendon injury.
Tu YJ, Liu YQ, Pan YY, Cai HY, Liu C
World journal of stem cells 2025 Nov 26;17(11):112393
World journal of stem cells 2025 Nov 26;17(11):112393
Sec14L6 is a phosphoinositide transporter that regulates phosphoinositide homeostasis and biogenesis of lipid droplets.
Zhou T, Xiong J, Hu X, Du Y, Shi A, Chang W, Qin J, Deng L, Ji WK
Nature communications 2025 Nov 26;16(1):10518
Nature communications 2025 Nov 26;16(1):10518
ER protein CLCC1 promotes nuclear envelope fusion in herpesviral and host processes.
Dai B, Sperl AW, Polack L, Mejia I, Dame H, Huynh T, Deveney C, Lavoie N, Lee C, Doench JG, Daugherty MD, Heldwein EE
Nature communications 2025 Nov 21;16(1):10256
Nature communications 2025 Nov 21;16(1):10256
Crucial roles of GALNT6-mediated O-glycosylation of GRP78/Bip in proliferation of breast cancer cells.
Uchiyama K, Hagiwara K, Matsushita Y, Yoshimaru T, Ono M, Sasa M, Katagiri T
Biochemical and biophysical research communications 2025 Nov 19;790:152868
Biochemical and biophysical research communications 2025 Nov 19;790:152868
Quercetin alleviated cadmium-induced oxidative stress, endoplasmic reticulum stress, and autophagy in chicken kidneys.
Shi Y, Yan B, Huang R, Yu W, Xu B, Mao J, Liu Z, Wang J
Environmental pollution (Barking, Essex : 1987) 2025 Nov 15;385:127058
Environmental pollution (Barking, Essex : 1987) 2025 Nov 15;385:127058
SIRT1 Alleviates Oxidative Stress-Induced Mitochondrial Dysfunction and Mitochondria-Associated Membrane Dysregulation in Stress Urinary Incontinence.
Chen L, Tang J, Zuo X, Li B, Liu C, Hong S, Min J, Hu M, Li S, Zhou M, Chen M, He Y, Xiao Y, Huang X, Hong L
Cell proliferation 2025 May;58(5):e70009
Cell proliferation 2025 May;58(5):e70009
Simulated microgravity activates autophagy expression in the rat retina.
Liu M, Wang Y, Ren F, Zhang W, Zheng H, Zhang R, Gao C, Luo L, Nie C, Gu J
Life sciences in space research 2025 May;45:107-116
Life sciences in space research 2025 May;45:107-116
The selenocysteine-containing protein SELENOT maintains dopamine signaling in the midbrain to protect mice from hyperactivity disorder.
Guo Q, Li ZF, Hu DY, Li PJ, Wu KN, Fan HH, Deng J, Wu HM, Zhang X, Zhu JH
The EMBO journal 2025 May;44(10):2906-2927
The EMBO journal 2025 May;44(10):2906-2927
FAM134B-mediated ER-phagy alleviates alcohol-related liver fibrosis by reducing endoplasmic reticulum stress.
Wang T, Li X, Xia G, Gong M, Lv X
International journal of biological macromolecules 2025 May;308(Pt 2):142395
International journal of biological macromolecules 2025 May;308(Pt 2):142395
SIRT5 modulates mitochondria function via mitophagy and antioxidant mechanisms to facilitate oocyte maturation in mice.
Yan JJ, Wang YY, Shi ZY, Ding YY, Wen HQ, Wu MP, Sun SC, Cai YF, Zhang Y
International journal of biological macromolecules 2025 May;306(Pt 2):141488
International journal of biological macromolecules 2025 May;306(Pt 2):141488
Grafting of syringic acid onto fucoidan: Enhanced functional properties and therapeutic potential in histamine-induced liver injury.
Zhang M, Tang J, Wang J, Qi C, Chen G, Chen W, Wang C
Food research international (Ottawa, Ont.) 2025 May;208:116161
Food research international (Ottawa, Ont.) 2025 May;208:116161
Discovery of a potent inhibitor of chaperone-mediated autophagy that targets the HSC70-LAMP2A interaction in non-small cell lung cancer cells.
Dong RF, Qin CJ, Yin Y, Han LL, Xiao CM, Wang KD, Wei RY, Xia YZ, Kong LY
British journal of pharmacology 2025 May;182(10):2287-2309
British journal of pharmacology 2025 May;182(10):2287-2309
USP51/GRP78/ABCB1 axis confers chemoresistance through decreasing doxorubicin accumulation in triple-negative breast cancer cells.
Ou Y, Zhang K, Shuai Q, Wang C, Hu H, Cao L, Qi C, Guo M, Li Z, Shi J, Liu Y, Zuo S, Chen X, Wang Y, Feng M, Wang H, Sun P, Shi Y, Yang G, Yang S
Acta pharmaceutica Sinica. B 2025 May;15(5):2593-2611
Acta pharmaceutica Sinica. B 2025 May;15(5):2593-2611
GRP78 Nanobody-Directed Immunotoxin Activates Innate Immunity Through STING Pathway to Synergize Tumor Immunotherapy.
Wang H, Zhou R, Xu C, Dai L, Hou R, Zheng L, Fu C, Shi G, Wang J, Li Y, Cen J, Xu X, Yu L, Li Y, Wang J, Du Q, Li Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 May;12(19):e2408086
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 May;12(19):e2408086
USP18 attenuates endoplasmic reticulum stress via the PERK-eIF2α-ATF4 axis to reduce apoptosis in hepatocellular carcinoma cells.
Li L, Liu N, Yang P, Rao C, Kong L, Huang Y, Lei Q, Liu H
Scientific reports 2025 May 5;15(1):15659
Scientific reports 2025 May 5;15(1):15659
Endoplasmic Reticulum Stress Inhibition Promotes Mitophagy via Miro1 Reduction to Rescue Mitochondrial Dysfunction and Protect Dopamine Neurons in Parkinson's Disease.
Wen Y, Han Z, Wang B, Feng C, Ding X, Li Y, Lv Y, Wang X, Gao L
Cellular and molecular neurobiology 2025 May 29;45(1):53
Cellular and molecular neurobiology 2025 May 29;45(1):53
Potential mechanisms by which Jiawei Lianpu Yin inhibits Helicobacter pylori colonization and alleviates gastric mucosal inflammation and damage: Integrated transcriptomics, network pharmacology, and experimental validation.
Zhang X, Wang L, Huang L, Cao G, Huang C, Duan Y, Lyu W
Journal of ethnopharmacology 2025 May 28;348:119793
Journal of ethnopharmacology 2025 May 28;348:119793
Lipid droplet accumulation impairs osseointegration by disturbing the osteogenesis-osteoclasis balance on titanium implant surface in hyperlipidemia.
Wang YN, Liu S
BMC oral health 2025 May 28;25(1):823
BMC oral health 2025 May 28;25(1):823
TRx0237 induces apoptosis and enhances anti-PD-1 immunotherapeutic efficacy in anaplastic thyroid Cancer.
Ning Q, Liu J, Liu S, Zou Q, Li K, Li Z
International immunopharmacology 2025 May 16;155:114610
International immunopharmacology 2025 May 16;155:114610
Aldehyde dehydrogenase 2 attenuates renal injury through inhibiting CYP4A expression.
Chen H, Hu Q, Lu Z, Zhao J, Liu A, Liu Z, Luo J, Ye Q, Zhong Z
Translational research : the journal of laboratory and clinical medicine 2025 Mar;277:1-12
Translational research : the journal of laboratory and clinical medicine 2025 Mar;277:1-12
Aerobic exercise improves energy and glucose homeostasis through hypothalamic Mitofusion 2-rescued endoplasmic reticulum stress in diet-induced obese mice.
Zhang S, Chen Y, Yang R, Ye L, Chen H, Jiang L, Bai D, Wu D
Diabetes, obesity & metabolism 2025 Mar;27(3):1251-1264
Diabetes, obesity & metabolism 2025 Mar;27(3):1251-1264
Age‑related changes in endoplasmic reticulum stress response‑associated protein expression in rat tibial nerves.
Sakita M, Isobe W, Nonaka K, Murakami S, Miyachi R, Sakane K, Sugimoto S, Yamaguchi A, Yamamoto K
Biomedical reports 2025 Mar;22(3):50
Biomedical reports 2025 Mar;22(3):50
Boric Acid Alleviates Lipopolysaccharide-Induced Acute Lung Injury in Mice.
Zhang X, Wang G, Chen S
Biological trace element research 2025 Mar;203(3):1494-1501
Biological trace element research 2025 Mar;203(3):1494-1501
Andrographolide ameliorates sepsis-induced acute liver injury by attenuating endoplasmic reticulum stress through the FKBP1A-mediated NOTCH1/AK2 pathway.
He J, Huang Z, Zou R
Cell biology and toxicology 2025 Mar 7;41(1):56
Cell biology and toxicology 2025 Mar 7;41(1):56
Clemastine fumarate alleviates endoplasmic reticulum stress through the Nur77/GFPT2/CHOP pathway after ischemia/reperfusion in rat hearts.
He Y, Sun F, Song C, Liu Y, Wang R, Wang Y, Sun X, Juan Z, Wang Y
International immunopharmacology 2025 Mar 6;149:114242
International immunopharmacology 2025 Mar 6;149:114242
Citrinin-Induced Intestinal Onset of Pyroptosis via the IP3R1-GRP75-VDAC1 Complex-Mediated Mitochondrial Oxidative Stress.
Li Y, Zhang Q, Liu X, Wang Y, Yang C, Wu Y, Xiao B, Feng Y, Wu A, Yi J, Wu J, Liang Z, Yuan Z
Journal of agricultural and food chemistry 2025 Mar 12;73(10):5803-5815
Journal of agricultural and food chemistry 2025 Mar 12;73(10):5803-5815
Triclosan Caused Oocyte Meiotic Arrest by Modulating Oxidative Stress, Organelle Dysfunctions, Autophagy, and Apoptosis in Pigs.
Zhao N, Xu A, Yang J, Zhao J, Xie J, Li B, Duan J, Cao G
Animals : an open access journal from MDPI 2025 Mar 12;15(6)
Animals : an open access journal from MDPI 2025 Mar 12;15(6)
Exogenous hydrogen sulfide improves non-alcoholic fatty liver disease by inhibiting endoplasmic reticulum stress/NLRP3 inflammasome pathway.
Fu X, Zhang Q, Chen Y, Li Y, Wang H
Molecular and cellular biochemistry 2025 Jun;480(6):3813-3839
Molecular and cellular biochemistry 2025 Jun;480(6):3813-3839
Endoplasmic Reticulum Stress and NLRP3 Inflammasome Activation Underlie Silver Nanoparticles-Induced Neurologic Deficits in Adult Mice.
Zhang W, Zhai M, Wu M, Yuan Y, Su X, Yang M, Ba Y, Deng Q, Zhang Y, Han L, Gao L, Huang H
Journal of biochemical and molecular toxicology 2025 Jun;39(6):e70289
Journal of biochemical and molecular toxicology 2025 Jun;39(6):e70289
Quercetin-loaded exosomes delivery system prevents myopia progression by targeting endoplasmic reticulum stress and ferroptosis in scleral fibroblasts.
Zhao L, Dong X, Guo B, Song J, Bi H
Materials today. Bio 2025 Jun;32:101896
Materials today. Bio 2025 Jun;32:101896
Polygonatum cyrtonema polysaccharide alleviates dopaminergic neuron apoptosis in Parkinson's disease mouse model via inhibiting oxidative stress and endoplasmic reticulum stress.
Li QM, Xu H, Zha XQ, Zhang FY, Luo JP
International journal of biological macromolecules 2025 Jun;311(Pt 3):143986
International journal of biological macromolecules 2025 Jun;311(Pt 3):143986
Lycopene regulates Nrf2 to Ameliorate Sulfamethoxazole -induced renal injury and apoptosis via inhibiting oxidative stress and Endoplasmic Reticulum stress.
Zhao H, Zhang Y, Cao Y, Zhou B, Xing M, Wang Y
Aquatic toxicology (Amsterdam, Netherlands) 2025 Jun;283:107348
Aquatic toxicology (Amsterdam, Netherlands) 2025 Jun;283:107348
Ultrasound-responsive taurine lipid nanoparticles attenuate oxidative stress and promote macrophage polarization for diabetic wound healing.
Luo Z, Zheng S, Hu Z, Li P, Zeng J, Lu Y, Ali M, Chen Z, Wang Q, Qi F
Free radical biology & medicine 2025 Jun;233:302-316
Free radical biology & medicine 2025 Jun;233:302-316
Reduced store operated calcium entry contributes to autophagy mediated escape of prostate cancer to oxaliplatin treatment.
Kannancheri Puthooru D, Yassine M, Gordienko D, Ziental-Gelus N, Desruelles E, Farfariello V, Lemonnier L, Prevarskaya N
Biochimica et biophysica acta. Molecular cell research 2025 Jun;1872(5):119953
Biochimica et biophysica acta. Molecular cell research 2025 Jun;1872(5):119953
Endoplasmic reticulum stress induces trophoblast pyroptosis via regulating CYLD during labor initiation.
Zhang X, Yang M, Lv D, Zhang Y, Xie Y, He M, Fan Y, Li X, Jallow F, Li F, Deng D
Placenta 2025 Jun 26;167:204-215
Placenta 2025 Jun 26;167:204-215
The Role of Endoplasmic Reticulum Stress in Fine Particulate Matter-Induced Phenotype Switching of Vascular Smooth Muscle Cells.
Huang L, Ding R, Yan K, Duan J, Sun Z
Chemical research in toxicology 2025 Jun 16;38(6):1072-1081
Chemical research in toxicology 2025 Jun 16;38(6):1072-1081
SREBF1 mediates immunoparalysis of dendritic cells in sepsis by regulating lipid metabolism and endoplasmic reticulum stress.
Zhang Y, Wu F, Li Y, Liu J, Zhu L, Zhang M, Lu Z
Cell communication and signaling : CCS 2025 Jun 16;23(1):286
Cell communication and signaling : CCS 2025 Jun 16;23(1):286
Regulatory Role of Tubulin Beta 1 in Oocyte Endoplasmic Reticulum Stress and Mitochondrial Integrity via Transforming Growth Factor-β1 Signaling Pathway in Mice.
Li Y, Dong Y, Lin X, Zhou X, Ma L, Jin H
Molecular reproduction and development 2025 Jul;92(7):e70042
Molecular reproduction and development 2025 Jul;92(7):e70042
Carfilzomib promotes Iodine-125 seed radiation-induced apoptosis, paraptosis, and ferroptosis in esophageal squamous cell carcinoma by aggravating endoplasmic reticulum stress.
Wang C, Zha YL, Wang H, Sun B, Qiang WG, Yuan Y, Shi HB, Hu WW
Translational oncology 2025 Jul;57:102393
Translational oncology 2025 Jul;57:102393
Effect of Voluntary Wheel Running on Anxiety- and Depression-Like Behaviors in Fluoride-Exposed Mice.
Qi M, Wu Y, Shi H, Liu J, Zhu R, Wang J, Rafique A, Yang B, Niu R, Zhang D, Sun Z
Biological trace element research 2025 Jul;203(7):3724-3741
Biological trace element research 2025 Jul;203(7):3724-3741
Constitutive Hepatic mTORC1 Activation Aggravates Alcohol-Induced Liver Injury via Endoplasmic Reticulum Stress-Mediated Ferroptosis.
Xu L, Zhao Y, Yang Y, Qi E, Liu B, Zhuang P, Song S, Chang T, Chen Z, Kang X, Xiong X
The American journal of pathology 2025 Jul;195(7):1209-1222
The American journal of pathology 2025 Jul;195(7):1209-1222
Koumine mediates the generation of mtROS through the IP3R1-GRP75-VDAC1 complex to improve Citrinin induced intestinal inflammation.
Li Y, Liu X, Zhang Q, Jiang Z, Zhang W, Yang C, Ni J, Deng S, Yi J, Wu J, Sun Z, Liang Z, Yuan Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul;142:156803
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul;142:156803
Icaritin induces paraptosis in hepatocellular carcinoma cells by targeting BHLHE40 via endoplasmic reticulum stress and mitochondrial dysfunction.
Wei W, Wang H, Fu L, Liu H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156870
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156870
COP I vesicles facilitate classical swine fever virus proliferation by transporting fatty acid synthase from the Golgi apparatus to the endoplasmic reticulum.
Zhang L, Wang T, Chen C, Song M, Li N, Luo B, Quan Y, Guo K, Zhang Y
Journal of virology 2025 Jul 22;99(7):e0030525
Journal of virology 2025 Jul 22;99(7):e0030525
ROS-Dependent Endoplasmic Reticulum Stress Is Involved in Silica-Induced Pulmonary Fibrosis through the GRP78/CHOP/TXNIP/NLRP3 Signaling Pathway in Rats.
Han GZ, Li S, Cui YY, Shao B, Song Y, Jiang SL, Zhang ZQ
Chemical research in toxicology 2025 Jul 21;38(7):1257-1265
Chemical research in toxicology 2025 Jul 21;38(7):1257-1265
A Diet Rich in Essential Amino Acids Inhibits the Growth of HCT116 Human Colon Cancer Cell In Vitro and In Vivo.
Corsetti G, Romano C, Codenotti S, Pasini E, Fanzani A, Scarabelli T, Dioguardi FS
International journal of molecular sciences 2025 Jul 21;26(14)
International journal of molecular sciences 2025 Jul 21;26(14)
The interaction between COX-2 and endoplasmic reticulum stress is involved in liver ischemia-reperfusion injury in mice.
Liang C, Guo L, Tian X, Mu Z, Chen M, Hu Y, Su J
Molecular biology reports 2025 Jul 15;52(1):710
Molecular biology reports 2025 Jul 15;52(1):710
Mechanisms underlying the estradiol mediated protection of yak oviduct epithelial cells against ER-Ca(2+) imbalance.
Ye X, Wang M, Pan Y, Li T, Wang J, Zhao L, Zhang R, Cui Y, Yu S
BMC genomics 2025 Jul 1;26(1):613
BMC genomics 2025 Jul 1;26(1):613
E3 ubiquitination ligase XIAP lightens diabetes-induced cognitive impairment by inactivating TXNIP-ERS-mediated neuronal injury.
Zhang Q, Huang HJ, Zhang JL, Tian Y, Hu Y
The Kaohsiung journal of medical sciences 2025 Jan;41(1):e12913
The Kaohsiung journal of medical sciences 2025 Jan;41(1):e12913
Anti-lung cancer synergy of low-dose doxorubicin and PD-L1 blocker co-delivered via mild photothermia-responsive black phosphorus.
Xu HZ, Chen FX, Li K, Zhang Q, Han N, Li TF, Xu YH, Chen Y, Chen X
Drug delivery and translational research 2025 Jan;15(1):269-290
Drug delivery and translational research 2025 Jan;15(1):269-290
Toosendanin alleviates acute lung injury by reducing pulmonary vascular barrier dysfunction mediated by endoplasmic reticulum stress through mTOR.
Mao X, Wang C, Tang H, Liu X, Wei C, Yin F, Fu T, Fang Y, Yu K, Zhang Z, Wu C, Liu H, Le A
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156277
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156277
Hypoxia Induced Lnc191 Upregulation Dictates the Progression of Esophageal Squamous Cell Carcinoma by Activating GRP78/ERK Pathway.
Wei S, Fan X, Li X, Zhou W, Zhang Z, Dai S, Lv H, Liu Y, Shan B, Zhao L, Zhan Q, Song Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jan;12(4):e2406674
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jan;12(4):e2406674
Caveolin 1 in bovine liver is associated with fatty acid-induced lipid accumulation and the endoplasmic reticulum unfolded protein response: Role in fatty liver development.
Li M, Zhao B, Wang J, Zhang H, Yang Y, Song S, Psifidi A, Wu W, Loor JJ, Xu C
Journal of dairy science 2025 Jan;108(1):1007-1021
Journal of dairy science 2025 Jan;108(1):1007-1021
Peach Gum Polysaccharide Prevents Chemotherapy-Induced Intestinal Injury and Degenerative Behavior.
Cui J, Wang W, Yi Z, Tian H, Wang H, Jiang C, Chen Y, Pi D, Chen Q, Wu Y
Integrative cancer therapies 2025 Jan-Dec;24:15347354251368410
Integrative cancer therapies 2025 Jan-Dec;24:15347354251368410
IL-17A exacerbates synovial inflammation in osteoarthritis via activation of endoplasmic reticulum stress.
Sun W, Li X, Zhang L, Zhang Y, Shi Y, Tao H, Zhou J, Hao Y, Chen G, Gu C, Yang X
International immunopharmacology 2025 Jan 3;145:113733
International immunopharmacology 2025 Jan 3;145:113733
Hypoxia-induced circPLOD2a/b promotes the aggressiveness of glioblastoma by suppressing XIRP1 through binding to HuR.
Yu A, Wang Y, Duan C, Qin J, Liao M, Zhu H, Lei J, Liu J, Yang Z, Yu L, Gui H, Xin J, Tao W, Bao W, Dong Z
Communications biology 2025 Jan 17;8(1):71
Communications biology 2025 Jan 17;8(1):71
The Differential Expressions and Associations of Intracellular and Extracellular GRP78/Bip with Disease Activity and Progression in Rheumatoid Arthritis.
Liu G, Wu J, Wang Y, Xu Y, Xu C, Fang G, Li X, Chen J
Bioengineering (Basel, Switzerland) 2025 Jan 13;12(1)
Bioengineering (Basel, Switzerland) 2025 Jan 13;12(1)
Daphnetin ameliorates diabetic cardiomyopathy by regulating inflammation and endoplasmic reticulum stress-induced apoptosis.
Zhao X, Shang L, Shen C
Experimental animals 2025 Jan 10;74(1):49-57
Experimental animals 2025 Jan 10;74(1):49-57
Perfluorooctane sulfonate causes HK-2 cell injury through ferroptosis and endoplasmic reticulum stress pathways.
Yan S, Ma H, Ren Y, Wang P, Liu D, Ding N, Liu Y, Chen Q, Ren S, Mou Y
Toxicology and industrial health 2025 Feb;41(2):73-82
Toxicology and industrial health 2025 Feb;41(2):73-82
HSP90 stabilizes visual cycle retinol dehydrogenase 5 in the endoplasmic reticulum by inhibiting its degradation during autophagy.
Jia X, Wang Y, Jiang M, Chen DD, Shang G, Liu B, Xue M, Lang Y, Zhou G, Dong Y, Zhang F, Peng X, Hu Y
The Journal of biological chemistry 2025 Feb;301(2):108126
The Journal of biological chemistry 2025 Feb;301(2):108126
Role of MFN2 in bovine embryonic development and the mitigation of ER stress.
Shi SM, Hu B, Chi ZC, Qu LY, Liu LY, He YY, Jia GL, Li JH, Kong I, Jin YX, Yu XF
Animal reproduction science 2025 Feb;273:107664
Animal reproduction science 2025 Feb;273:107664
Taurine mechanism in preventing retinal cell damage from acute ocular hypertension through GTPBP3 regulation.
Lu W, Yang Y, Gao S, Wu J, Sun X
Experimental eye research 2025 Feb;251:110222
Experimental eye research 2025 Feb;251:110222
Hydrogen Sulfide Promotes TAM-M1 Polarization through Activating IRE-1α Pathway via GRP78 S-Sulfhydrylation to against Breast Cancer.
Ju M, Tong W, Bi J, Zeng X, Qi A, Sun M, Wen J, Zhao L, Wei M
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(8):e2413607
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(8):e2413607
Targeting ceramide transfer protein sensitizes AML to FLT3 inhibitors via a GRP78-ATF6-CHOP axis.
Sun X, Li Y, Du J, Liu F, Wu C, Xiao W, Yu G, Chen X, Gale RP, Zeng H
Nature communications 2025 Feb 4;16(1):1358
Nature communications 2025 Feb 4;16(1):1358
Effect of Dync1h1 on Phototransduction Protein Transport and the Development and Maintenance of Photoreceptor Cells in Zebrafish.
Zhou X, Cao J, Xie J, Tong W, Jia B, Fu J
Investigative ophthalmology & visual science 2025 Feb 3;66(2):38
Investigative ophthalmology & visual science 2025 Feb 3;66(2):38
Mesalazine alleviated the symptoms of spontaneous colitis in interleukin-10 knockout mice by regulating the STAT3/NF-κB signaling pathway.
Chen Q, Zhang YL, Shi YQ, Zheng L
World journal of gastroenterology 2025 Feb 21;31(7):96459
World journal of gastroenterology 2025 Feb 21;31(7):96459
TIM8 Deficiency in Yeast Induces Endoplasmic Reticulum Stress and Shortens the Chronological Lifespan.
Tang D, Guan W, Yang X, Li Z, Zhao W, Liu X
Biomolecules 2025 Feb 12;15(2)
Biomolecules 2025 Feb 12;15(2)
Yinchen-Gancao decoction ameliorated NASH in mice by reducing hepatic lipid accumulation, inhibiting hepatic inflammatory and endoplasmic reticulum stress.
Zhao J, Jin J, Li Y, Zhang S, Li F, Cui J, Wang Z, Yan D, Qiu F
Journal of ethnopharmacology 2025 Feb 11;341:119318
Journal of ethnopharmacology 2025 Feb 11;341:119318
SIRT6 inhibits endoplasmic reticulum stress-mediated ferroptosis by activating Nrf2/HO-1 signaling to alleviate osteoarthritis.
Shi J, Chen L, Wang X, Ma X
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2025 Feb 10;74(1):35
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2025 Feb 10;74(1):35
Xuebijing injection alleviates septic acute kidney injury by modulating inflammation, mitochondrial dysfunction, and endoplasmic reticulum stress.
Zhang L, Zhang G, Mao W, Sun S, Tao S, Gao Y, Zhang N, Jiang G, Chen M, Lu X, Chen S
Renal failure 2025 Dec;47(1):2483986
Renal failure 2025 Dec;47(1):2483986
Study on the effect of HMGB1 on immune cells isolated from SLE mice.
Qin X, Gao J, Liu X, Chen J, Song X
Biochemistry and biophysics reports 2025 Dec;44:102262
Biochemistry and biophysics reports 2025 Dec;44:102262
Glabridin Alleviates Metabolic Disorders in Diet-Induced Diabetic Mice.
Yang X, Lai K, Zhang J, Chen Z, Ding W, Jiang Y, Liu Y
Phytotherapy research : PTR 2025 Dec;39(12):5551-5566
Phytotherapy research : PTR 2025 Dec;39(12):5551-5566
The T-type voltage-gated Ca(2+) channel Ca(V)3.1 involves in the disruption of respiratory epithelial barrier induced by Pasteurella multocida toxin.
Bi H, Wang F, Lin L, Zhang D, Chen M, Shang Y, Hua L, Chen H, Wu B, Peng Z
Virulence 2025 Dec;16(1):2466482
Virulence 2025 Dec;16(1):2466482
Carvacrol alleviates endoplasmic reticulum stress and inflammation induced by lipopolysaccharide by enhancing endoplasmic reticulum autophagy in dairy mammary epithelial cells.
Yang Y, Li M, Wang J, Zhang H, Chang R, Zhao B, Aernouts B, Huang Q, Xu C
Journal of dairy science 2025 Dec;108(12):13919-13937
Journal of dairy science 2025 Dec;108(12):13919-13937
DDRGK1 preserves intervertebral disc development through ufmylation.
Lu M, Zhou T, Yang X, Liu K, Rong K, Ma P, Qin A, Zhao J
Cellular and molecular life sciences : CMLS 2025 Dec 29;83(1):47
Cellular and molecular life sciences : CMLS 2025 Dec 29;83(1):47
An Enhanced Cancer Immunogenic Cell Death Strategy: Fibrate-Oxaliplatin(IV) Conjugates with Modulating Tumor Immune Microenvironment.
Liang XJ, Guo X, Zhu PH, Zhao ZH, You Z, Yang K, Song Y, Li L, Song XQ
Journal of medicinal chemistry 2025 Dec 25;68(24):26328-26347
Journal of medicinal chemistry 2025 Dec 25;68(24):26328-26347
Knockdown of FXYD2 inhibits mepivacaine-induced cardiomyocyte injury by activating the PI3K/AKT signaling pathway.
Cheng L, Wang B, Chen J, Qiao X, Jiang J, Sun Y
European journal of medical research 2025 Dec 18;31(1):121
European journal of medical research 2025 Dec 18;31(1):121
A combination of ethanol and arachidonic acid promotes steatosis and endoplasmic reticulum stress and impairs mitochondrial respiration in H9c2 cardiomyoblasts.
Ai W, New E, Casey CA, Saraswathi V
Lipids in health and disease 2025 Dec 16;24(1):385
Lipids in health and disease 2025 Dec 16;24(1):385
FUT3 mediated GRP78 fucosylation promotes colorectal cancer survival and proliferation under glucose restriction via PERK/ATF4/STC2 axis.
Qin K, Zhang H, Shi Y, Wu R, Wu C, Wu Y, He C, Han Z, Luo Y, Fang Y, Yan X, Wang X, Li M, Li A, Liu S, Li Q
NPJ precision oncology 2025 Dec 14;10(1):19
NPJ precision oncology 2025 Dec 14;10(1):19
Cross-Species Insights into In Vitro Maturation Defects of the Oocyte and Identification of Crucial Regulators for Sheep Oocyte Maturation.
Cui J, Zhao X, Hao J, Liu X, Wang W, He L, Wang Y, Rong J, Qiu C, Chen D, Cheng L, Tian J, Zhang J, Xi G
Antioxidants (Basel, Switzerland) 2025 Dec 13;14(12)
Antioxidants (Basel, Switzerland) 2025 Dec 13;14(12)
A study on the mechanism by which BCAT1 influences the formation of intracranial aneurysms by regulating autophagy through endoplasmic reticulum stress.
Liu S, Guan H, Wang F
International immunopharmacology 2025 Dec 10;167:115667
International immunopharmacology 2025 Dec 10;167:115667
KLF10-IN-1 Attenuates RPE Cell Apoptosis and Experimental Diabetic Retinopathy Via the KLF10/PERK/eIF2α/ATF4/CHOP Pathway.
Hu W, Yang H, Zhu Q, Zheng G, Tan J, Lin Y, Wang Y, Tu Y, Zhou Q
Investigative ophthalmology & visual science 2025 Dec 1;66(15):25
Investigative ophthalmology & visual science 2025 Dec 1;66(15):25
Pathology-oriented multiplexing enables integrative disease mapping.
Kuehl M, Okabayashi Y, Wong MN, Gernhold L, Gut G, Kaiser N, Schwerk M, Gräfe SK, Ma FY, Tanevski J, Schäfer PSL, Mezher S, Sarabia Del Castillo J, Goldbeck-Strieder T, Zolotareva O, Hartung M, Delgado Chaves FM, Klinkert L, Gnirck AC, Spehr M, Fleck D, Joodaki M, Parra V, Shaigan M, Diebold M, Prinz M, Kranz J, Kux JM, Braun F, Kretz O, Wu H, Grahammer F, Heins S, Zimmermann M, Haas F, Kylies D, Wanner N, Czogalla J, Dumoulin B, Zolotarev N, Lindenmeyer M, Karlson P, Nyengaard JR, Sebode M, Weidemann S, Wiech T, Groene HJ, Tomas NM, Meyer-Schwesinger C, Kuppe C, Kramann R, Karras A, Bruneval P, Tharaux PL, Pastene D, Yard B, Schaub JA, McCown PJ, Pyle L, Choi YJ, Yokoo T, Baumbach J, Sáez PJ, Costa I, Turner JE, Hodgin JB, Saez-Rodriguez J, Huber TB, Bjornstad P, Kretzler M, Lenoir O, Nikolic-Paterson DJ, Pelkmans L, Bonn S, Puelles VG
Nature 2025 Aug;644(8076):516-526
Nature 2025 Aug;644(8076):516-526
Berberine Enhances the Sensitivity of Colorectal Cancer Cells to 5-FU Through Smoothing Endoplasmic Reticulum Stress-Mediated Autophagic Flux.
Xu J, Hu M, Li Y, Gong H, Zhang X, He Z, Xiao C, Yang C, Zeng J
Cell biology international 2025 Aug;49(8):1042-1055
Cell biology international 2025 Aug;49(8):1042-1055
Yinchenhao Decoction Combined with Praziquantel Ameliorates Inflammation and Hepatic Fibrosis in Schistosoma japonicum-Infected Mice.
Liu JH, Peng M, Chen F, Song QY, Zhang LC, Liao Y, Song LG, Wu ZD
Current medical science 2025 Aug;45(4):944-956
Current medical science 2025 Aug;45(4):944-956
Combined downregulation of TGF-β1 and GRP78 is responsible for overcoming acquired sorafenib resistance, which is initiated by rewiring the cell surface CD44-GRP78-IGF-1R signaling circuit.
Li S, Oh GH, Hong JA, Choi S, Kim M, Kwon H, Ko SK, Park SJ, Kim HK, Choi HJ, Song JJ
Cancer gene therapy 2025 Aug;32(8):884-898
Cancer gene therapy 2025 Aug;32(8):884-898
Protective effect of β-carotene against lipopolysaccharide-induced meiotic maturation defects in porcine cumulus-oocytes complexes.
Chen M, Li J, He Y, Wang W, Ju S, Li Q
Animal reproduction science 2025 Aug;279:107947
Animal reproduction science 2025 Aug;279:107947
Cadmium induces autophagy via IRE1 signaling pathway activated by Ca(2 +) in GC-2spd cells.
Han Y, Dai J, Cheng J, He Y, Zhao C, Li R, Zhang Y, Zhang L, Zhou T, Shi Y
Reproductive toxicology (Elmsford, N.Y.) 2025 Aug;135:108950
Reproductive toxicology (Elmsford, N.Y.) 2025 Aug;135:108950
HSP90 deficiency promotes cholesteryl ester accumulation in lipid droplets via endocytosis of low-density lipoprotein.
Ma C, Che X, Liang Y, Li J, Yu K, Zhao TJ, Li P, Chen FJ
Communications biology 2025 Aug 6;8(1):1169
Communications biology 2025 Aug 6;8(1):1169
Cardiopulmonary Bypass-Induced IL-17A Aggravates Caspase-12-Dependent Neuronal Apoptosis Through the Act1-IRE1-JNK1 Pathway.
Zhao R, Ma Y, Li S, Li J
Biomolecules 2025 Aug 6;15(8)
Biomolecules 2025 Aug 6;15(8)
Heat shock proteins related signature characterizes immune status and predicts prognosis of gliomas.
Sun Z, Wan H, Du M, Guo Y, Tao R, Zhao X, Zhang Y, Yang P, Zhou D
Scientific reports 2025 Aug 5;15(1):28652
Scientific reports 2025 Aug 5;15(1):28652
Dimethyl fumarate improves non-alcoholic fatty liver disease by regulating SIRT1 signal to inhibit MAMs over-enrichment.
Zhang R, Zhang Q, Cui Z, Huang B, Wang Y, Ma H
European journal of pharmacology 2025 Aug 5;1000:177693
European journal of pharmacology 2025 Aug 5;1000:177693
FICD (FIC Domain Protein Adenylyl Transferase) Deficiency Protects Mice From Hypertrophy-Induced Heart Failure and Promotes BiP (Binding Immunoglobulin Protein) -Mediated Activation of the Unfolded Protein Response and Endoplasmic Reticulum-Selective Autophagy in Cardiomyocytes.
Lacy SM, Taubitz RJ, Urban ND, Turowski SN, Primack EN, Smith ED, Helms AS, Michele DE, Truttmann MC
Journal of the American Heart Association 2025 Aug 19;14(16):e040192
Journal of the American Heart Association 2025 Aug 19;14(16):e040192
Functionally deficient UBOX5 variants and primary angle-closure glaucoma.
Li Z, Chng WL, Liu Z, Do T, Nakano M, Chen LJ, Loo Y, Chan ASY, Topouzis F, Nongpiur ME, Ozaki M, Nakano S, Kubota T, Perera SA, Husain R, Wong TTL, Cheng CY, Ho CL, Abu-Amero K, Wong HT, Melo MB, Hien NDTN, Van Trinh N, Huong NTT, Azhany Y, Perez-Grossmann R, Chan PP, Stuart KV, Biradar MI, Szabo A, Anastasopoulos E, Giannoulis DA, Ntonti P, Papakonstantinou E, Lambropoulos A, Chatzikyriakidou A, Kilintzis V, Ayub H, Micheal S, Aung YY, Leuenberger EU, Fea A, Mon NN, Anajao A, Bi X, Kok YJ, Chong RS, Boey PY, Tan DZJ, Sin WWL, Chowbay B, Khaing CC, Aung YM, Reyes RD, Panagiotou ES, Mikropoulos DG, Voudouragkaki IC, Panos GD, Xie Z, Chen XY, Lim YT, Meah WY, Lee YS, Ho CEH, Yeo PMX, Ikeda Y, Tokuda Y, Tanaka M, Omi N, Ueno M, de Vasconcellos JPC, Costa VP, Abe RY, de Souza BB, Fong GB, Castro VV, Fujita R, Guevara-Fujita ML, Akhtar F, Ali M, Catacutan MAT, Felarca IR, Liao CS, Lavia C, Than HM, Oo KT, Soe-Kyaw PP, Frezzotti P, Pasutto F, Quino R, Minn-Din Z, Oo NL, Dallorto L, Set SH, Doan VH, Qamar R, Neto JM, Al-Obeidan S, Tham CC, Mori K, Sotozono C, Kinoshita S, Konstas AG, Liza-Sharmini AT, Zenteno JC, Do NH, Foster PJ, Tashiro K, Pang CP, Khawaja AP, Aung T, Wang Z, Khor CC
Nature communications 2025 Aug 15;16(1):7620
Nature communications 2025 Aug 15;16(1):7620
Glia maturation factor-β in hepatocytes enhances liver regeneration and mitigates steatosis and ballooning in zebrafish.
Li HY, Zeng WL, Ye YW, Chen X, Zhang MM, Chen YS, Liu CT, Zhong ZQ, Li J, Wang Y
American journal of physiology. Gastrointestinal and liver physiology 2025 Aug 1;329(2):G291-G306
American journal of physiology. Gastrointestinal and liver physiology 2025 Aug 1;329(2):G291-G306
Klotho improves Der p1-induced bronchial epithelial cell damage by inhibiting endoplasmic reticulum stress to regulate mitochondrial function.
Wang C, Liu Z, Xie X, Li Y, Sun L
Tissue & cell 2025 Apr;93:102646
Tissue & cell 2025 Apr;93:102646
ETS1 promotes cisplatin resistance of NSCLC cells by promoting GRP78 transcription.
Liu C, Jiang J, Luo J, Zhang Y, Yang C, Shi J
Naunyn-Schmiedeberg's archives of pharmacology 2025 Apr;398(4):4633-4643
Naunyn-Schmiedeberg's archives of pharmacology 2025 Apr;398(4):4633-4643
The long noncoding RNA APR attenuates PPRV infection-induced accumulation of intracellular iron to inhibit membrane lipid peroxidation and viral replication.
Wen B, Chang W, Yang L, Lv D, Wang L, Wang L, Xu Y, Hu J, Ding K, Xue Q, Qi X, Yang B, Wang J
mBio 2025 Apr 9;16(4):e0012725
mBio 2025 Apr 9;16(4):e0012725
Small-Molecule FICD Inhibitors Suppress Endogenous and Pathologic FICD-Mediated Protein AMPylation.
Chatterjee BK, Alam M, Chakravorty A, Lacy SM, Giblin W, Rech J, Brooks CL 3rd, Arvan P, Truttmann MC
ACS chemical biology 2025 Apr 18;20(4):880-895
ACS chemical biology 2025 Apr 18;20(4):880-895
PERK/Sestrin2 Signaling Pathway Mediated Autophagy Regulates Human Cardiomyocytes Apoptosis Induced by Traffic-Related PM(2.5) and Diverse Constituents.
Tian J, Niu Z, Yang H, Wang C, Guan L, Zhao L, Shi D, Zhang Z
International journal of molecular sciences 2025 Apr 17;26(8)
International journal of molecular sciences 2025 Apr 17;26(8)
TLR4-mediated endoplasmic reticulum stress regulates pyroptosis in macrophages infected with the Bacillus Calmette-Guérin mycobacterial.
Nie X, Miao S, Hou Y, Ma Y, Li M, Liu Y, Yang Y, Xu J, Wang Y
International immunopharmacology 2025 Apr 16;152:114346
International immunopharmacology 2025 Apr 16;152:114346
Luteolin Modulate Endoplasmic Reticulum Stress by Targeting SIRT1 to Ameliorate DSS-Induced Ulcerative Colitis in Mice.
Guo HX, Ji ZH, Wang BB, Xiao Y, Hu JP, Zheng Y, Gao W, Yuan B
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Apr 15;39(7):e70529
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Apr 15;39(7):e70529
Effect of 1-DNJ on Oxidative Stress-Induced Apoptosis in Porcine Ovarian GCs Through Modulation of the PERK-ATF4/MFN2 Signaling Pathway.
Xing W, Li M, Wang B, Huo L, Tian W, Ge F, Shen M, Sun L, Liu J, Yu S
Antioxidants (Basel, Switzerland) 2025 Apr 11;14(4)
Antioxidants (Basel, Switzerland) 2025 Apr 11;14(4)
Dissection of the potential mechanism of polystyrene microplastic exposure on cardiomyocytes.
Xue D, Huang J, Sun X, Zhang W, Ma H, Yin D, Wang Y, Wang J, Yang C, Geng Q
The Science of the total environment 2025 Apr 10;973:179048
The Science of the total environment 2025 Apr 10;973:179048
SIGMAR1 screened by a GPCR-related classifier regulates endoplasmic reticulum stress in bladder cancer.
Zhuang J, Wang Y, Wu X, Peng Z, Huang Z, Zhao C, Shen B
Journal of translational medicine 2025 Apr 10;23(1):417
Journal of translational medicine 2025 Apr 10;23(1):417
Mutant p53 upregulates HDAC6 to resist ER stress and facilitates Ku70 deacetylation, which prevents its degradation and mitigates DNA damage in colon cancer cells.
Benedetti R, Di Crosta M, Gilardini Montani MS, D'Orazi G, Cirone M
Cell death discovery 2025 Apr 10;11(1):162
Cell death discovery 2025 Apr 10;11(1):162
ITGB1 Alleviates High Glucose-Induced Myocardial Cell Injury by Inhibiting Endoplasmic Reticulum Stress and Cell Apoptosis.
Cheng C, Li J, Zhang D, Xu D, Yu W
International heart journal 2024;65(6):1137-1143
International heart journal 2024;65(6):1137-1143
Knocking-down annexin A3 suppresses inflammation, oxidative stress, apoptosis, and endoplasmic reticulum stress to attenuate sepsis-induced acute kidney injury in HK2 cells.
Su J, Wang L, Guan X, Li N, Sun L
CytoJournal 2024;21:75
CytoJournal 2024;21:75
CRISPR/CasRx-Mediated Knockdown of Rab7B Restores Incomplete Cell Shape Induced by Pelizaeus-Merzbacher Disease-Associated PLP1 p.Ala243Val.
Fukushima N, Miyamoto Y, Yamauchi J
Neuroscience insights 2024;19:26331055241276873
Neuroscience insights 2024;19:26331055241276873
SIRT1 inhibits apoptosis of human lens epithelial cells through suppressing endoplasmic reticulum stress in vitro and in vivo.
Cui H, Sun D, Meng S, Ma TJ, Ye Z, Li ZH
International journal of ophthalmology 2024;17(7):1205-1216
International journal of ophthalmology 2024;17(7):1205-1216
Maresin-1 Attenuates Sepsis-Associated Acute Kidney Injury via Suppressing Inflammation, Endoplasmic Reticulum Stress and Pyroptosis by Activating the AMPK/SIRT3 Pathway.
Sun M, Wang F, Li H, Li M, Wang Y, Wang C, Zhang Y, Zhang D, Li J, Yao S
Journal of inflammation research 2024;17:1349-1364
Journal of inflammation research 2024;17:1349-1364
Puerarin attenuates myocardial ischemic injury and endoplasmic reticulum stress by upregulating the Mzb1 signal pathway.
Xue J, Ren H, Zhang Q, Gu J, Xu Q, Sun J, Zhang L, Zhou MS
Frontiers in pharmacology 2024;15:1442831
Frontiers in pharmacology 2024;15:1442831
Protective effect of naringenin on cadmium chloride-induced renal injury via alleviating oxidative stress, endoplasmic reticulum stress, and autophagy in chickens.
Shi Y, Gao Z, Xu B, Mao J, Wang Y, Liu Z, Wang J
Frontiers in pharmacology 2024;15:1440877
Frontiers in pharmacology 2024;15:1440877
Azoramide ameliorates cadmium-induced cytotoxicity by inhibiting endoplasmic reticulum stress and suppressing oxidative stress.
Zhang L, Zhang J, Zhou Y, Xia Q, Xie J, Zhu B, Wang Y, Yang Z, Li J
PeerJ 2024;12:e16844
PeerJ 2024;12:e16844
PKD regulates mitophagy to prevent oxidative stress and mitochondrial dysfunction during mouse oocyte maturation.
Liu YP, He B, Wang WX, Pan WL, Jiao L, Yan JJ, Sun SC, Zhang Y
Mitochondrion 2024 Sep;78:101946
Mitochondrion 2024 Sep;78:101946
Irisflorentin improves functional recovery after spinal cord injury by protecting the blood-spinal cord barrier and promoting axonal growth.
Hu Z, Tan H, Zhang Y, Qi T, Li Y, Li N, Zhou Z, Wang Y, Wang H, Zhang H, Wang Q
Experimental neurology 2024 Sep;379:114886
Experimental neurology 2024 Sep;379:114886
UFL1 regulates cellular homeostasis by targeting endoplasmic reticulum and mitochondria in NEFA-stimulated bovine mammary epithelial cells via the IRE1α/XBP1 pathway.
Yan Y, Huang J, Chen X, Li Y, Zhao W, Li C
Free radical biology & medicine 2024 Sep;222:16-26
Free radical biology & medicine 2024 Sep;222:16-26
Zinc-Mediated Endoplasmic Reticulum Stress and Metallothionein Alleviate Arsenic-Induced Cardiotoxicity in Cyprinus Carpio.
Dong H, Song H, Liu Y, Zou H
Biological trace element research 2024 Sep;202(9):4203-4215
Biological trace element research 2024 Sep;202(9):4203-4215
The RhoB p.S73F mutation leads to cerebral palsy through dysregulation of lipid homeostasis.
Wu X, Liu R, Zhang Z, Yang J, Liu X, Jiang L, Fang M, Wang S, Lai L, Song Y, Li Z
EMBO molecular medicine 2024 Sep;16(9):2002-2023
EMBO molecular medicine 2024 Sep;16(9):2002-2023
A 700 nm LED Light Activated Ru(II) Complex Destroys Tumor Cytoskeleton via Photosensitization and Photocatalysis.
Dao A, Chen S, Pan L, Ren Q, Wang X, Wu H, Gong Q, Chen Z, Ji S, Ru J, Zhu H, Liang C, Zhang P, Xia H, Huang H
Advanced healthcare materials 2024 Sep;13(23):e2400956
Advanced healthcare materials 2024 Sep;13(23):e2400956
Attenuation of PM2.5-Induced Lung Injury by 4-Phenylbutyric Acid: Maintenance of [Ca(2+)]i Stability between Endoplasmic Reticulum and Mitochondria.
Ma Z, Du X, Sun Y, Jia Y, Liang X, Gao Y
Biomolecules 2024 Sep 8;14(9)
Biomolecules 2024 Sep 8;14(9)
GRP78/IRE1 and cGAS/STING pathway crosstalk through CHOP facilitates iodoacetic acid-mediated testosterone decline.
Mou L, Sun D, Qu J, Tan X, Wang S, Zeng Q, Liu C
Journal of hazardous materials 2024 Sep 5;476:135101
Journal of hazardous materials 2024 Sep 5;476:135101
Discovery of novel quinoline scaffold selective estrogen receptor degraders (SERDs) for treatment of ER positive breast cancer with enhanced antiproliferative bioactivity through immunogenic cell death (ICD) effects.
Lu Y, Liang Z, Liu L, Zhou Y, Liu C, Zhao Z, Zheng T, Du Q, Liu W
European journal of medicinal chemistry 2024 Sep 5;275:116534
European journal of medicinal chemistry 2024 Sep 5;275:116534
CLCC1 promotes membrane fusion during herpesvirus nuclear egress.
Dai B, Polack L, Sperl A, Dame H, Huynh T, Deveney C, Lee C, Doench JG, Heldwein EE
bioRxiv : the preprint server for biology 2024 Sep 23;
bioRxiv : the preprint server for biology 2024 Sep 23;
Strategically engineered Au(I) complexes for orchestrated tumor eradication via chemo-phototherapy and induced immunogenic cell death.
Feng N, Peng Z, Zhang X, Lin Y, Hu L, Zheng L, Tang BZ, Zhang J
Nature communications 2024 Sep 18;15(1):8187
Nature communications 2024 Sep 18;15(1):8187
Cepharanthine triggers ferroptosis through inhibition of NRF2 for robust ER stress against lung cancer.
Bai XF, Hu J, Wang MF, Li LG, Han N, Wang H, Chen NN, Gao YJ, You H, Wang X, Xu X, Yu TT, Li TF, Ren T
European journal of pharmacology 2024 Sep 15;979:176839
European journal of pharmacology 2024 Sep 15;979:176839
TMC7 deficiency causes acrosome biogenesis defects and male infertility in mice.
Wang J, Yin Y, Yang L, Qin J, Wang Z, Qiu C, Gao Y, Lu G, Gao F, Chen ZJ, Zhang X, Liu H, Liu Z
eLife 2024 Sep 13;13
eLife 2024 Sep 13;13
DMDD, isolated from Averrhoa carambola L., ameliorates diabetic nephropathy by regulating endoplasmic reticulum stress-autophagy crosstalk.
Shi J, Wang Y, Liang T, Wang X, Xie J, Huang R, Xu X, Wei X
Chinese medicine 2024 Sep 12;19(1):125
Chinese medicine 2024 Sep 12;19(1):125
Endoplasmic reticulum stress is attenuated by glycolysis in lymphatic malformations.
Li X, Zhong W, Jiang H, Wang P, Chai M, Zhu T, Liu J, Huang C, Yang S, Mou D, Zhou X, Cai Y
Pediatric research 2024 Oct;96(5):1210-1219
Pediatric research 2024 Oct;96(5):1210-1219
Nimbolide protects against diabetic cardiomyopathy by regulating endoplasmic reticulum stress and mitochondrial function via the Akt/mTOR pathway.
Zhang H, Zhao X, Wei W, Shen C
Tissue & cell 2024 Oct;90:102478
Tissue & cell 2024 Oct;90:102478
Astragaloside IV ameliorated neuroinflammation and improved neurological functions in mice exposed to traumatic brain injury by modulating the PERK-eIF2α-ATF4 signaling pathway.
Zhao J, Zhao G, Lang J, Sun B, Feng S, Li D, Sun G
Journal of investigative medicine : the official publication of the American Federation for Clinical Research 2024 Oct;72(7):747-762
Journal of investigative medicine : the official publication of the American Federation for Clinical Research 2024 Oct;72(7):747-762
Inhibiting endoplasmic reticulum stress alleviates perioperative neurocognitive disorders by reducing neuroinflammation mediated by NLRP3 inflammasome activation.
Meng F, Song J, Huang X, Zhang M, Sun X, Jing Q, Cao S, Xie Z, Liu Q, Zhang H, Li C
CNS neuroscience & therapeutics 2024 Oct;30(10):e70049
CNS neuroscience & therapeutics 2024 Oct;30(10):e70049
CaMKII suppresses proteotoxicity by phosphorylating BAG3 in response to proteasomal dysfunction.
Zhang C, Xu H, Tang Q, Duan Y, Xia H, Huang H, Ye D, Bi F
EMBO reports 2024 Oct;25(10):4488-4514
EMBO reports 2024 Oct;25(10):4488-4514
Quantitative proteomics reveals the mechanism of endoplasmic reticulum stress-mediated pulmonary fibrosis in mice.
Li H, Wang J, Li Z, Wu Z, Zhang Y, Kong L, Yang Q, Wang D, Shi H, Shen G, Zou S, Zhu W, Fan K, Xu Z
Heliyon 2024 Oct 30;10(20):e39150
Heliyon 2024 Oct 30;10(20):e39150
Taohong Siwu decoction alleviates cognitive impairment by suppressing endoplasmic reticulum stress and apoptosis signaling pathway in vascular dementia rats.
Fan LL, Fang H, Zheng JY, Qiu YH, Wu GL, Cai YF, Chen YB, Zhang SJ
Journal of ethnopharmacology 2024 Oct 28;333:118407
Journal of ethnopharmacology 2024 Oct 28;333:118407
An atlas of the aging mouse proteome reveals the features of age-related post-transcriptional dysregulation.
Takasugi M, Nonaka Y, Takemura K, Yoshida Y, Stein F, Schwarz JJ, Adachi J, Satoh J, Ito S, Tombline G, Biashad SA, Seluanov A, Gorbunova V, Ohtani N
Nature communications 2024 Oct 2;15(1):8520
Nature communications 2024 Oct 2;15(1):8520
Endoplasmic reticulum stress promotes oxidative stress, inflammation, and apoptosis: A novel mechanism of citrinin-induced renal injury and dysfunction.
Wang Y, Li Y, Wu Y, Wu A, Xiao B, Liu X, Zhang Q, Feng Y, Yuan Z, Yi J, Wu J, Yang C
Ecotoxicology and environmental safety 2024 Oct 1;284:116946
Ecotoxicology and environmental safety 2024 Oct 1;284:116946
Apoptosis mediated by crosstalk between mitochondria and endoplasmic reticulum: A possible cause of citrinin disruption of the intestinal barrier.
Li Y, Wang Y, Jiang Z, Yang C, Wu Y, Wu A, Zhang Q, Liu X, Xiao B, Feng Y, Wu J, Liang Z, Yuan Z
Ecotoxicology and environmental safety 2024 Oct 1;284:116877
Ecotoxicology and environmental safety 2024 Oct 1;284:116877
Liquiritigenin inhibits the migration, invasion, and EMT of prostate cancer through activating ER stress.
Wang C, Liu B, Dan W, Wei Y, Li M, Guo C, Zhang Y, Xie H
Archives of biochemistry and biophysics 2024 Nov;761:110184
Archives of biochemistry and biophysics 2024 Nov;761:110184
NUS1 Variants Cause Lennox-Gastaut Syndrome Related to Unfolded Protein Reaction Activation.
Shen NX, Qu XC, Yu J, Fan CX, Min FL, Li LY, Zhang MR, Li BM, Wang J, He N, Liao WP, Shi YW, Li WB
Molecular neurobiology 2024 Nov;61(11):8518-8530
Molecular neurobiology 2024 Nov;61(11):8518-8530
OBHSA, a novel selective estrogen receptor degrader, overcomes tamoxifen resistance through cell cycle arrest and unfolded protein response-mediated apoptosis in breast cancer.
Shen R, Zhou J, Xin L, Zhou HB, Huang J
The Journal of steroid biochemistry and molecular biology 2024 Nov;244:106599
The Journal of steroid biochemistry and molecular biology 2024 Nov;244:106599
Role of PERK-Mediated Endoplasmic Reticulum Stress in Ferroptosis Caused by Hexavalent Chromium in Chicken Hepatocytes.
Cui Y, Zhang P, Song K, Qi C, Liu Y, Liu J
Biological trace element research 2024 Nov;202(11):5208-5218
Biological trace element research 2024 Nov;202(11):5208-5218
Involvement of spinal NADPH oxidase 4 and endoplasmic reticulum stress in morphine-tolerant rats.
Xiao X, Yang J, Bai Q, Wang Z, Chen Y, Si Y, Xu Y, Li Z, Bu H
Journal of neurochemistry 2024 Nov;168(11):3745-3759
Journal of neurochemistry 2024 Nov;168(11):3745-3759
Endo-Lysosomal Network Disorder Reprograms Energy Metabolism in SorL1-Null Rat Hippocampus.
Wang Y, Yang Y, Cai Y, Aobulikasimu A, Wang Y, Hu C, Miao Z, Shao Y, Zhao M, Hu Y, Xu C, Chen X, Li Z, Chen J, Wang L, Chen S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Nov;11(41):e2407709
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Nov;11(41):e2407709
GLCCI1 alleviates GRP78-initiated endoplasmic reticulum stress-induced apoptosis of retinal ganglion cells in diabetic retinopathy by upregulating and interacting with HSP90AB1.
Liu J, Yu H, Yu S, Liu M, Chen X, Wang Y, Li J, Shi C, Liu W, Zuo Z, Liu X
Scientific reports 2024 Nov 4;14(1):26665
Scientific reports 2024 Nov 4;14(1):26665
MIF promotes Th17 cell differentiation in rheumatoid arthritis through ATF6 signal pathway.
Yan G, Song R, Zhang J, Li Z, Lu Z, Liu Z, Zeng X, Yao J
Molecular medicine (Cambridge, Mass.) 2024 Nov 29;30(1):237
Molecular medicine (Cambridge, Mass.) 2024 Nov 29;30(1):237
HNF-1β alleviates podocyte injury in lupus nephritis by maintaining endoplasmic reticulum homeostasis.
Zou HM, Yu J, Ruan YY, Xie Y, An XM, Chen PL, Luo YQ, Shi MJ, Liu M, Xu LF, Liu J, Guo B, Zhang F
Lupus science & medicine 2024 Nov 27;11(2)
Lupus science & medicine 2024 Nov 27;11(2)
DEPTOR attenuates asthma progression by suppressing endoplasmic reticulum stress through SOD1.
Wang H, Zhang L, Shang Y
Biology direct 2024 Nov 12;19(1):114
Biology direct 2024 Nov 12;19(1):114
SIRT1-Dependent Neuroprotection by Resveratrol in TOCP-Induced Spinal Cord Injury: Modulation of ER Stress and Autophagic Flux.
Tian X, Ou Y, Shi S, Zhou Q, Long S, Xiang Y, Zhao W, Long D
Toxics 2024 Nov 11;12(11)
Toxics 2024 Nov 11;12(11)
Fucoxanthin ameliorates endoplasmic reticulum stress and inhibits apoptosis and alleviates intervertebral disc degeneration in rats by upregulating Sirt1.
Teng C, Wu J, Zhang Z, Wang J, Yang Y, Dong C, Wu L, Lin Z, Hu Y, Wang J, Zhang X, Lin Z
Phytotherapy research : PTR 2024 May;38(5):2114-2127
Phytotherapy research : PTR 2024 May;38(5):2114-2127
4-PBA exerts brain-protective effects against sepsis-associated encephalopathy in a mouse model of sepsis.
Xiong F, Wang C, Lu J, Bai G, Zhou D, Ling J
Experimental neurology 2024 May;375:114738
Experimental neurology 2024 May;375:114738
Mechanism of Qili Qiangxin Capsule for Heart Failure Based on miR133a-Endoplasmic Reticulum Stress.
Ji XD, Yang D, Cui XY, Lou LX, Nie B, Zhao JL, Zhao MJ, Wu AM
Chinese journal of integrative medicine 2024 May;30(5):398-407
Chinese journal of integrative medicine 2024 May;30(5):398-407
Apelin‑13 reduces high glucose‑induced mitochondrial dysfunction in cochlear hair cells by inhibiting endoplasmic reticulum stress.
Huo Z, Gu J, He T
Experimental and therapeutic medicine 2024 May;27(5):226
Experimental and therapeutic medicine 2024 May;27(5):226
p20BAP31 Induces Autophagy in Colorectal Cancer Cells by Promoting PERK-Mediated ER Stress.
Jiang X, Li G, Zhu B, Yang J, Cui S, Jiang R, Wang B
International journal of molecular sciences 2024 May 7;25(10)
International journal of molecular sciences 2024 May 7;25(10)
AGR2-mediated unconventional secretion of 14-3-3ε and α-actinin-4, responsive to ER stress and autophagy, drives chemotaxis in canine mammary tumor cells.
Yuan SH, Wu CC, Wang YC, Chan XY, Chu HW, Yang Y, Liu HP
Cellular & molecular biology letters 2024 May 31;29(1):84
Cellular & molecular biology letters 2024 May 31;29(1):84
LY86 facilitates ox-LDL-induced lipid accumulation in macrophages by upregulating SREBP2/HMGCR expression.
Jiang G, Li J, Niu S, Dong R, Chen Y, Bi W
BMC cardiovascular disorders 2024 May 31;24(1):289
BMC cardiovascular disorders 2024 May 31;24(1):289
Urolithin A's Role in Alleviating Severe Acute Pancreatitis via Endoplasmic Reticulum-Mitochondrial Calcium Channel Modulation.
Kang H, Hu Q, Yang Y, Huang G, Li J, Zhao X, Zhu L, Su H, Tang W, Wan M
ACS nano 2024 May 28;18(21):13885-13898
ACS nano 2024 May 28;18(21):13885-13898
Therapeutic Potential of Fucoidan in Alleviating Histamine-Induced Liver Injury: Insights from Mice Studies.
Zhang M, Liu H, Xu L, Zhang X, Chen W, Wang C
Foods (Basel, Switzerland) 2024 May 14;13(10)
Foods (Basel, Switzerland) 2024 May 14;13(10)
Juan-tong-yin potentially impacts endometriosis pathophysiology by enhancing autophagy of endometrial stromal cells via unfolded protein reaction-triggered endoplasmic reticulum stress.
Meng F, Li J, Dong K, Bai R, Liu Q, Lu S, Liu Y, Wu D, Jiang C, Li W
Journal of ethnopharmacology 2024 May 10;325:117859
Journal of ethnopharmacology 2024 May 10;325:117859
Esculin suppresses the PERK-eIF2α-CHOP pathway by enhancing SIRT1 expression in oxidative stress-induced rat chondrocytes, mitigating osteoarthritis progression in a rat model.
Cheng Z, Liu Z, Liu C, Yang A, Miao H, Bai X
International immunopharmacology 2024 May 10;132:112061
International immunopharmacology 2024 May 10;132:112061
Edaravone counteracts redox and metabolic disruptions in an emerging zebrafish model of sporadic ALS.
Oliveira NAS, Pinho BR, Pinto J, Guedes de Pinho P, Oliveira JMA
Free radical biology & medicine 2024 May 1;217:126-140
Free radical biology & medicine 2024 May 1;217:126-140
The down-regulation of STC2 mRNA may serve as a biomarker for death from mechanical asphyxia.
Hu Y, Han L, Zhang H, Li W, Wu T, Ma J, Zhang D, Ma K, Xiao B, Yu Y, Xu H, Tian L, Liao X, Chen L
Legal medicine (Tokyo, Japan) 2024 Mar;67:102382
Legal medicine (Tokyo, Japan) 2024 Mar;67:102382
D-pinitol alleviates diabetic cardiomyopathy by inhibiting the optineurin-mediated endoplasmic reticulum stress and glycophagy signaling pathway.
Li X, Yu X, Yu F, Fu C, Zhao W, Liu X, Dai C, Gao H, Cheng M, Li B
Phytotherapy research : PTR 2024 Mar;38(3):1681-1694
Phytotherapy research : PTR 2024 Mar;38(3):1681-1694
A combination of PD-L1-targeted IL-15 mRNA nanotherapy and ultrasound-targeted microbubble destruction for tumor immunotherapy.
Wang X, Li F, Zhang J, Guo L, Shang M, Sun X, Xiao S, Shi D, Meng D, Zhao Y, Jiang C, Li J
Journal of controlled release : official journal of the Controlled Release Society 2024 Mar;367:45-60
Journal of controlled release : official journal of the Controlled Release Society 2024 Mar;367:45-60
Prolyl isomerase Pin1 sculpts the immune microenvironment of colorectal cancer.
Li Y, Yuan Z, Wang L, Yang J, Pu P, Le Y, Chen X, Wang C, Gao Y, Liu Y, Wang J, Gao X, Li Y, Wang H, Zou C
Cellular signalling 2024 Mar;115:111041
Cellular signalling 2024 Mar;115:111041
Curculigoside Attenuates Endoplasmic Reticulum Stress-Induced Epithelial Cell and Fibroblast Senescence by Regulating the SIRT1-P300 Signaling Pathway.
Xie W, Deng L, Qian R, Huang X, Liu W, Tang S
Antioxidants (Basel, Switzerland) 2024 Mar 29;13(4)
Antioxidants (Basel, Switzerland) 2024 Mar 29;13(4)
Rolapitant treats lung cancer by targeting deubiquitinase OTUD3.
Du T, Gu Q, Zhang Y, Gan Y, Liang R, Yang W, Lu Y, Xu C, Wu J, Ma R, Cao H, Jiang J, Wang J, Feng J
Cell communication and signaling : CCS 2024 Mar 27;22(1):195
Cell communication and signaling : CCS 2024 Mar 27;22(1):195
Iron overload in hypothalamic AgRP neurons contributes to obesity and related metabolic disorders.
Zhang Y, Chen L, Xuan Y, Zhang L, Tian W, Zhu Y, Wang J, Wang X, Qiu J, Yu J, Tang M, He Z, Zhang H, Chen S, Shen Y, Wang S, Zhang R, Xu L, Ma X, Liao Y, Hu C
Cell reports 2024 Mar 26;43(3):113900
Cell reports 2024 Mar 26;43(3):113900
FBXO22 promotes glioblastoma malignant progression by mediating VHL ubiquitination and degradation.
Shen Z, Dong T, Yong H, Deng C, Chen C, Chen X, Chen M, Chu S, Zheng J, Li Z, Bai J
Cell death discovery 2024 Mar 23;10(1):151
Cell death discovery 2024 Mar 23;10(1):151
The Effects of Endoplasmic Reticulum Stress via Intratracheal Instillation of Water-Soluble Acrylic Acid Polymer on the Lungs of Rats.
Morimoto T, Izumi H, Tomonaga T, Nishida C, Kawai N, Higashi Y, Wang KY, Ono R, Sumiya K, Sakurai K, Moriyama A, Takeshita JI, Yamasaki K, Yatera K, Morimoto Y
International journal of molecular sciences 2024 Mar 22;25(7)
International journal of molecular sciences 2024 Mar 22;25(7)
Brain transcriptomic, metabolic and mitohormesis properties associated with N-propargylglycine treatment: A prevention strategy against neurodegeneration.
Teramayi F, Bons J, Scott M, Scott GK, Loureiro A, Lopez-Ramirez A, Schilling B, Ellerby LM, Benz CC
Brain research 2024 Mar 1;1826:148733
Brain research 2024 Mar 1;1826:148733
DNAJC10 maintains survival and self-renewal of leukemia stem cells through PERK branch of the unfolded protein response.
Li M, Wu X, Chen M, Hao S, Yu Y, Li X, Zhao E, Xu M, Yu Z, Wang Z, Xu N, Jin C, Yin Y
Haematologica 2024 Mar 1;109(3):751-764
Haematologica 2024 Mar 1;109(3):751-764
Inhibition of HDAC6 with CAY10603 alleviates acute and chronic kidney injury by suppressing the ATF6 branch of UPR.
Kan S, Hou Q, Yang R, Yang F, Zhang M, Liu Z, Jiang S
Archives of biochemistry and biophysics 2024 Jun;756:110009
Archives of biochemistry and biophysics 2024 Jun;756:110009
CircRNA_0088196 Regulates Trophoblast Proliferation and Apoptosis in Preeclampsia Through the miR-379-5p/HSPA5 Axis.
Xiong Z, Wang Q, Pei S, Zheng H, Wang W
Biochemical genetics 2024 Jun;62(3):1742-1761
Biochemical genetics 2024 Jun;62(3):1742-1761
Melatonin alleviates endoplasmic reticulum stress and follicular granulosa cell apoptosis by regulating ATF4 to activate mTOR signaling pathway in chickens.
Hao EY, Liu XL, Chen XY, Xue H, Su BF, Chen YF, Wang DH, Shi L, Bai K, Hou F, Hou JK, Bao HL, Chen H
Poultry science 2024 Jun;103(6):103656
Poultry science 2024 Jun;103(6):103656
Deacetylated MDH1 and IDH1 aggravates PANoptosis in acute liver failure through endoplasmic reticulum stress signaling.
Shi C, Wang Y, Guo J, Zhang D, Zhang Y, Gong Z
Cell death discovery 2024 Jun 8;10(1):275
Cell death discovery 2024 Jun 8;10(1):275
Using an ER-specific optogenetic mechanostimulator to understand the mechanosensitivity of the endoplasmic reticulum.
Song Y, Zhao Z, Xu L, Huang P, Gao J, Li J, Wang X, Zhou Y, Wang J, Zhao W, Wang L, Zheng C, Gao B, Jiang L, Liu K, Guo Y, Yao X, Duan L
Developmental cell 2024 Jun 3;59(11):1396-1409.e5
Developmental cell 2024 Jun 3;59(11):1396-1409.e5
TSWIFT, a novel method for iterative staining of embedded and mounted human brain sections.
Porter CM, Tabler S, Choi S, Truttmann MC
Scientific reports 2024 Jun 3;14(1):12688
Scientific reports 2024 Jun 3;14(1):12688
p97 inhibits integrated stress response-induced neuronal apoptosis after subarachnoid hemorrhage in mice by enhancing proteasome function.
Cheng W, Wei B, Liu W, Jin L, Guo S, Ding M, Liu Y, Fan H, Li R, Zhang X, He X, Li X, Duan C
Experimental neurology 2024 Jul;377:114778
Experimental neurology 2024 Jul;377:114778
Dietary α-Ketoglutarate Alleviates Escherichia coli LPS-Induced Intestinal Barrier Injury by Modulating the Endoplasmic Reticulum-Mitochondrial System Pathway in Piglets.
Lu J, Liu G, Sun W, Jia G, Zhao H, Chen X, Wang J
The Journal of nutrition 2024 Jul;154(7):2087-2096
The Journal of nutrition 2024 Jul;154(7):2087-2096
Enterovirus 3A protein disrupts endoplasmic reticulum homeostasis through interaction with GBF1.
Hirano J, Hayashi T, Kitamura K, Nishimura Y, Shimizu H, Okamoto T, Okada K, Uemura K, Yeh MT, Ono C, Taguwa S, Muramatsu M, Matsuura Y
Journal of virology 2024 Jul 23;98(7):e0081324
Journal of virology 2024 Jul 23;98(7):e0081324
Deubiquitylase OTUD3 regulates integrated stress response to suppress progression and sorafenib resistance of liver cancer.
Dai H, Wu B, Ge Y, Hao Y, Zhou L, Hong R, Zhang J, Jiang W, Zhang Y, Li H, Zhang L
Cell reports 2024 Jul 23;43(7):114487
Cell reports 2024 Jul 23;43(7):114487
Intake of Special Amino Acids Mixture Leads to Blunted Murine Colon Cancer Growth In Vitro and In Vivo.
Corsetti G, Romano C, Codenotti S, Giugno L, Pasini E, Fanzani A, Scarabelli T, Dioguardi FS
Cells 2024 Jul 18;13(14)
Cells 2024 Jul 18;13(14)
Small molecule FICD inhibitors suppress endogenous and pathologic FICD-mediated protein AMPylation.
Chatterjee BK, Alam M, Chakravorty A, Lacy SM, Rech J, Brooks CL 3rd, Arvan PD, Truttmann MC
bioRxiv : the preprint server for biology 2024 Jul 16;
bioRxiv : the preprint server for biology 2024 Jul 16;
Copper exposure induces mitochondrial dysfunction and hepatotoxicity via the induction of oxidative stress and PERK/ATF4 -mediated endoplasmic reticulum stress.
Li M, Tang S, Velkov T, Shen J, Dai C
Environmental pollution (Barking, Essex : 1987) 2024 Jul 1;352:124145
Environmental pollution (Barking, Essex : 1987) 2024 Jul 1;352:124145
Suppression of endoplasmic reticulum stress by 4-PBA enhanced atherosclerotic plaque stability via up-regulating CLOCK expression.
Zhu G, Gao H, Li Y, Li X, Yang X, Wang C, Guo Z, Fan H, Fan L
Pathology, research and practice 2024 Jan;253:154969
Pathology, research and practice 2024 Jan;253:154969
Maternal obstructive sleep apnea aggravates metabolic dysfunction-associated fatty liver disease via HMGB1-TLR4 signaling-mediated endoplasmic reticulum stress in male offspring rats.
Wang R, Feng W, Wang Y, Jiang Y, Lin Y, Chen X
Biochimica et biophysica acta. Molecular basis of disease 2024 Jan;1870(1):166889
Biochimica et biophysica acta. Molecular basis of disease 2024 Jan;1870(1):166889
Dietary xylo-oligosaccharides alleviates LPS-induced intestinal injury via endoplasmic reticulum-mitochondrial system pathway in piglets.
Liu G, Sun W, Zhang R, Shen F, Jia G, Zhao H, Chen X, Wang J
Journal of animal science 2024 Jan 3;102
Journal of animal science 2024 Jan 3;102
Endoplasmic reticulum stress caused by traumatic injury promotes cardiomyocyte apoptosis through acetylation modification of GRP78.
Yan Z, Liu Y, Yang B, Zhao W, Wang Y, Wang D, Li J, Jiao X, Cao J
Acta biochimica et biophysica Sinica 2024 Jan 25;56(1):96-105
Acta biochimica et biophysica Sinica 2024 Jan 25;56(1):96-105
Selenium-SelK-GPX4 axis protects nucleus pulposus cells against mechanical overloading-induced ferroptosis and attenuates senescence of intervertebral disc.
Jia C, Xiang Z, Zhang P, Liu L, Zhu X, Yu R, Liu Z, Wang S, Liu K, Wang Z, Vasilev K, Zhou S, Geng Z, Liu X, Zhao Y, Gao Y, Cheng L, Li Y
Cellular and molecular life sciences : CMLS 2024 Jan 22;81(1):49
Cellular and molecular life sciences : CMLS 2024 Jan 22;81(1):49
Mic19 depletion impairs endoplasmic reticulum-mitochondrial contacts and mitochondrial lipid metabolism and triggers liver disease.
Dong J, Chen L, Ye F, Tang J, Liu B, Lin J, Zhou PH, Lu B, Wu M, Lu JH, He JJ, Engelender S, Meng Q, Song Z, He H
Nature communications 2024 Jan 2;15(1):168
Nature communications 2024 Jan 2;15(1):168
Cell surface GRP78: A potential therapeutic target for high glucose-induced endothelial injury.
Wang B, He X, Zhang J, Zhang Y
Biochemical and biophysical research communications 2024 Jan 15;692:149347
Biochemical and biophysical research communications 2024 Jan 15;692:149347
Patulin induces ROS-dependent cardiac cell toxicity by inducing DNA damage and activating endoplasmic reticulum stress apoptotic pathway.
Zhang B, Huang C, Xu D, Huang K, Li Y, Jiao L, Fu B, Li S, Li Y
Ecotoxicology and environmental safety 2024 Jan 1;269:115784
Ecotoxicology and environmental safety 2024 Jan 1;269:115784
Methane-Rich Saline Suppresses ER-Mitochondria Contact and Activation of the NLRP3 Inflammasome by Regulating the PERK Signaling Pathway to Ameliorate Intestinal Ischemia‒Reperfusion Injury.
Li Z, Wang B, Tian L, Zheng B, Zhao X, Liu R
Inflammation 2024 Feb;47(1):376-389
Inflammation 2024 Feb;47(1):376-389
Pentapeptide PYRAE triggers ER stress-mediated apoptosis of breast cancer cells in mice by targeting RHBDF1-BiP interaction.
Ryu S, Long H, Zheng XL, Song YY, Wang Y, Zhou YJ, Quan XJ, Li LY, Zhang ZS
Acta pharmacologica Sinica 2024 Feb;45(2):378-390
Acta pharmacologica Sinica 2024 Feb;45(2):378-390
The role and mechanism of RIPK1 in vascular endothelial dysfunction in chronic kidney disease.
Wang C, Chen H, Su H, Sheng Q, Lang Y, Yu Q, Lv Z, Wang R
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Feb;38(2):e23446
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Feb;38(2):e23446
Lysine demethylase KDM3A alleviates hyperoxia-induced bronchopulmonary dysplasia in mice by promoting ETS1 expression.
Yang M, Chen Y, Huang X, Shen F, Meng Y
Experimental cell research 2024 Feb 15;435(2):113945
Experimental cell research 2024 Feb 15;435(2):113945
Bile acids metabolism in the gut-liver axis mediates liver injury during lactation.
Huang L, Li Y, Tang R, Yang P, Zhuo Y, Jiang X, Che L, Lin Y, Xu S, Li J, Fang Z, Zhao X, Li H, Yang M, Feng B, Wu D, Hua L
Life sciences 2024 Feb 1;338:122380
Life sciences 2024 Feb 1;338:122380
BRD4 absence inactivates endoplasmic reticulum stress to retard dehydroepiandrosterone-triggered ovarian granular cell apoptosis in polycystic ovary syndrome via GRP78.
Zhang Y, Wang J
Tissue & cell 2024 Dec;91:102531
Tissue & cell 2024 Dec;91:102531
Particulate matter induced cognitive impairments via endoplasmic reticulum stress-mediated damage to mitochondria-associated endoplasmic reticulum membranes in immature rats.
Wang L, Gui J, Tian B, Ding R, Wang W, Jiang C, Zhang S, Zhang X, Liu J, Jiang L
Toxicology 2024 Dec;509:153979
Toxicology 2024 Dec;509:153979
Perfluorooctane sulfonate causes damage to L-02 cells via Wnt/β-catenin signal path and endoplasmic reticulum stress pathway.
Jiajing C, Shuqi Y, Haoyan M, Pingwei W, Dongge L, Yanping L, Qianqian C, Saleh F, Shuping R
Toxicology and industrial health 2024 Dec;40(12):653-666
Toxicology and industrial health 2024 Dec;40(12):653-666
Pachymic acid ameliorates bleomycin-induced pulmonary fibrosis through inhibiting endoplasmic reticulum stress in rats.
Li L, Jin RJ, Ji L
Environmental toxicology 2024 Dec;39(12):5382-5390
Environmental toxicology 2024 Dec;39(12):5382-5390
Gelsolin alleviates rheumatoid arthritis by negatively regulating NLRP3 inflammasome activation.
Lee J, Sasaki F, Koike E, Cho M, Lee Y, Dho SH, Lee J, Lee E, Toyohara E, Sunakawa M, Ishibashi M, Hung HH, Nishioka S, Komine R, Okura C, Shimizu M, Ikawa M, Yoshimura A, Morita R, Kim LK
Cell death and differentiation 2024 Dec;31(12):1679-1694
Cell death and differentiation 2024 Dec;31(12):1679-1694
Endoplasmic reticulum stress induces renal fibrosis in high‑fat diet mice via the TGF‑β/SMAD pathway.
Mu Z, Li B, Chen M, Liang C, Gu W, Su J
Molecular medicine reports 2024 Dec;30(6)
Molecular medicine reports 2024 Dec;30(6)
Selenium participates in the formation of kidney stones by alleviating endoplasmic reticulum stress and apoptosis of renal tubular epithelial cells.
Su X, Chen H, Xiang H, Ke H, Dong C, Song Q, Zhou J, Jiang Q, Wang Y, Chen L, Yang S
Redox report : communications in free radical research 2024 Dec;29(1):2416825
Redox report : communications in free radical research 2024 Dec;29(1):2416825
Sigma-1 receptor exerts protective effects on ameliorating nephrolithiasis by modulating endoplasmic reticulum-mitochondrion association and inhibiting endoplasmic reticulum stress-induced apoptosis in renal tubular epithelial cells.
Ke H, Su X, Dong C, He Z, Song Q, Song C, Zhou J, Liao W, Wang C, Yang S, Xiong Y
Redox report : communications in free radical research 2024 Dec;29(1):2391139
Redox report : communications in free radical research 2024 Dec;29(1):2391139
TMAO induces pyroptosis of vascular endothelial cells and atherosclerosis in ApoE(-/-) mice via MBOAT2-mediated endoplasmic reticulum stress.
Yu B, Yuan C, Chen J, Zhou Z, Zhang Y, Su M, Wei D, Wu P
Biochimica et biophysica acta. Molecular and cell biology of lipids 2024 Dec;1869(8):159559
Biochimica et biophysica acta. Molecular and cell biology of lipids 2024 Dec;1869(8):159559
Grass Carp Reovirus (GCRV) infection activates the PERK-eIF2α pathway to promote the viral replication.
Shen Z, Qi Y, Yu W, Li S, Liu Z, Li L, Zhu M, Gong C, Hu X
Fish & shellfish immunology 2024 Dec;155:110020
Fish & shellfish immunology 2024 Dec;155:110020
Cepharanthine-mediated endoplasmic reticulum stress inhibits Notch1 via binding GRP78 for suppressing hepatocellular carcinoma metastasis.
Hu J, Chen NN, Li LG, Yu TT, Qin Y, Peng XC, Li HT, Li XY, Ma TQ, Lu YH, Han N, Xu Z, Hui YJ, Li TF
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156162
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156162
Corilagin alleviated intestinal ischemia-reperfusion injury by modulating endoplasmic reticulum stress via bonding with Bip.
Wang Y, Liu G, Qiu F, Li X, Diao Y, Yang M, Yang S, Li B, Han Q, Liu J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156011
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156011
TUDCA inhibits EV71 replication by regulating ER stress signaling pathway and suppressing autophagy.
Wang S, Liu R, Zhou Y, Xu J, Su A, Zheng D
Diagnostic microbiology and infectious disease 2024 Dec;110(4):116500
Diagnostic microbiology and infectious disease 2024 Dec;110(4):116500
Ginkgolide A enhances FoxO1 expression and reduces endoplasmic reticulum stress to mitigate osteoarthritis in mice.
Yu H, Liang J, Bao Y, Chen K, Jin Y, Li X, Chen H, Gou Y, Lu K, Lin Z
International immunopharmacology 2024 Dec 5;142(Pt B):113116
International immunopharmacology 2024 Dec 5;142(Pt B):113116
Endoplasmic reticulum stress-MMRN1 positive feedback contributes to cisplatin resistance in small cell lung cancer.
Liu M, Hu P, Tang B, Yang Q, Xiang R, Liu Y, Li J, Wu B, Wu H, Tian B, Xu C, Li Q
Journal of thoracic disease 2024 Dec 31;16(12):8363-8378
Journal of thoracic disease 2024 Dec 31;16(12):8363-8378
Guilu Erxian glue reduces endoplasmic reticulum stress-mediated apoptosis and restores the balance of extracellular matrix synthesis and degradation in chondrocytes by inhibiting the ATF6/GRP78/CHOP signaling pathway.
Geng Q, Wu W, Yang M, Gu F, Cai W, Qin Y, Wei L, Wang H, Li N
Heliyon 2024 Dec 30;10(24):e39987
Heliyon 2024 Dec 30;10(24):e39987
SUCNR 1 promotes atherosclerosis by inducing endoplasmic reticulum stress mediated ER-mito crosstalk.
Yuan C, Yu B, Li L, Chen J, Qin W, Zhou Z, Su M, Wang D, Zhang Y, Wu Q, He C, Wei D
International immunopharmacology 2024 Dec 25;143(Pt 3):113510
International immunopharmacology 2024 Dec 25;143(Pt 3):113510
Possible Involvement of X-Box Binding Protein-1 in the Onset of Pulpitis.
Naruse T, Takeda K, Yoshida K, Sasaki S, Kumagai T, Takahashi Y, Kawai R, Nakanishi J, Shiba H
European endodontic journal 2024 Dec 20;9(4):335-343
European endodontic journal 2024 Dec 20;9(4):335-343
miR-421-mediated suppression of FGF13 as a novel mechanism ameliorates cardiac hypertrophy by inhibiting endoplasmic reticulum stress.
Zhi Y, Duan Y, Zhang Y, Hu H, Hu F, Wang P, Liu B, Wang C, Liu D, Gu G
European journal of pharmacology 2024 Dec 15;985:177085
European journal of pharmacology 2024 Dec 15;985:177085
Neuritin attenuates neuroinflammation and apoptosis in early brain injury after subarachnoid hemorrhage via endoplasmic reticulum stress-related inflammatory pathways.
Ren K, Dai L, Zhang H, He Y, Liu B, Hu Y, Ma K, Tian W, Zhao D
Brain research 2024 Dec 15;1845:149293
Brain research 2024 Dec 15;1845:149293
Puerarin Attenuates Insulin Resistance by Inhibiting Endoplasmic Reticulum Stress and Suppresses Inflammation by Modulating the JNK and IKKβ/NF-κB Pathways in Epididymal White Adipose Tissue of Mice on a High-Fat Diet.
Sun J, Liu Y, Zhang J, Shi H, Jiang R, Guo M, Liu Y, Liu B, Wang N, Ma R, Zhang D, Zhang F, Wang S, Wu Y
Molecular nutrition & food research 2024 Aug;68(16):e2400003
Molecular nutrition & food research 2024 Aug;68(16):e2400003
Benzo[a]pyrene exposure disrupts the organelle distribution and function of mouse oocytes.
Wang PX, Wu SL, Ju JQ, Jiao L, Zou YJ, Zhang KH, Sun SC, Hu LL, Zheng XB
Ecotoxicology and environmental safety 2024 Aug;281:116630
Ecotoxicology and environmental safety 2024 Aug;281:116630
Sex-related differences in SIRT3-mediated mitochondrial dynamics in renal ischemia/reperfusion injury.
Yao H, Zhao H, Du Y, Zhang Y, Li Y, Zhu H
Translational research : the journal of laboratory and clinical medicine 2024 Aug;270:1-12
Translational research : the journal of laboratory and clinical medicine 2024 Aug;270:1-12
ATF6 supports lysosomal function in tumor cells to enable ER stress-activated macroautophagy and CMA: impact on mutant TP53 expression.
Benedetti R, Romeo MA, Arena A, Gilardini Montani MS, D'Orazi G, Cirone M
Autophagy 2024 Aug;20(8):1854-1867
Autophagy 2024 Aug;20(8):1854-1867
Maltol Improves Peripheral Nerve Function by Inhibiting Schwann Cell Apoptosis via the PERK/eIF2α/CHOP Pathway and MME Upregulation in Diabetic Peripheral Neuropathy.
Li J, Liu Q, Liu S, Xin H, Zhang X, Guo N
Pharmaceuticals (Basel, Switzerland) 2024 Aug 29;17(9)
Pharmaceuticals (Basel, Switzerland) 2024 Aug 29;17(9)
Knockdown of Rab9 Recovers Defective Morphological Differentiation Induced by Chemical ER Stress Inducer or PMD-Associated PLP1 Mutant Protein in FBD-102b Cells.
Fukushima N, Miyamoto Y, Yamauchi J
Pathophysiology : the official journal of the International Society for Pathophysiology 2024 Aug 26;31(3):420-435
Pathophysiology : the official journal of the International Society for Pathophysiology 2024 Aug 26;31(3):420-435
TFG regulates inner COPII coat recruitment to facilitate anterograde secretory protein transport.
Kasberg W, Luong P, Minushkin K, Pustova I, Swift KA, Zhao M, Audhya A
Molecular biology of the cell 2024 Aug 1;35(8):ar113
Molecular biology of the cell 2024 Aug 1;35(8):ar113
Phenylbutyric acid inhibits hypoxia-induced trophoblast apoptosis and autophagy in preeclampsia via the PERK/ATF-4/CHOP pathway.
Li Y, Guo Y, Wu D, Ai L, Wu R, Ping Z, Zhu K
Molecular reproduction and development 2024 Apr;91(4):e23742
Molecular reproduction and development 2024 Apr;91(4):e23742
GDI2 deletion alleviates neurodegeneration and memory loss in the 5xFAD mice model of Alzheimer's disease.
Wang M, He X, Li J, Han D, You P, Yu H, Wang L, Su B
Biochimica et biophysica acta. Molecular basis of disease 2024 Apr;1870(4):167093
Biochimica et biophysica acta. Molecular basis of disease 2024 Apr;1870(4):167093
Low-Intensity Extracorporeal Shock Wave Therapy Ameliorates Detrusor Hyperactivity with Impaired Contractility via Transient Potential Vanilloid Channels: A Rat Model for Ovarian Hormone Deficiency.
Chueh KS, Juan TJ, Lu JH, Wu BN, Lin RJ, Mao JW, Lin HY, Chuang SM, Chang CY, Shen MC, Sun TW, Juan YS
International journal of molecular sciences 2024 Apr 30;25(9)
International journal of molecular sciences 2024 Apr 30;25(9)
Up-regulation of HSP90α in HDM-induced asthma causes pyroptosis of airway epithelial cells by activating the cGAS-STING-ER stress pathway.
Huang H, Qiao Y, Chu L, Ye C, Lin L, Liao H, Meng X, Zou F, Zhao H, Zou M, Cai S, Dong H
International immunopharmacology 2024 Apr 20;131:111917
International immunopharmacology 2024 Apr 20;131:111917
Ketogenic diet ameliorates high-fat diet-induced insulin resistance in mouse skeletal muscle by alleviating endoplasmic reticulum stress.
Ma Q, Jiang L, You Y, Ni H, Ma L, Lin X, Wang Z, Yan W, Xiao X, Li X, Li J
Biochemical and biophysical research communications 2024 Apr 2;702:149559
Biochemical and biophysical research communications 2024 Apr 2;702:149559
Xbp1 promotes odontoblastic differentiation through modulating mitochondrial homeostasis.
Huang D, Li Y, Han J, Zuo H, Liu H, Chen Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Apr 15;38(7):e23600
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Apr 15;38(7):e23600
TDCPP and TiO(2) NPs aggregates synergistically induce SH-SY5Y cell neurotoxicity by excessive mitochondrial fission and mitophagy inhibition.
Wang L, Wang B, Zhang X, Yang Z, Zhang X, Gong H, Song Y, Zhang K, Sun M
Environmental pollution (Barking, Essex : 1987) 2024 Apr 15;347:123740
Environmental pollution (Barking, Essex : 1987) 2024 Apr 15;347:123740
Triptolide induces apoptosis and cytoprotective autophagy by ROS accumulation via directly targeting peroxiredoxin 2 in gastric cancer cells.
Chen P, Zhong X, Song Y, Zhong W, Wang S, Wang J, Huang P, Niu Y, Yang W, Ding Z, Luo Q, Yang C, Wang J, Zhang W
Cancer letters 2024 Apr 10;587:216622
Cancer letters 2024 Apr 10;587:216622
Systems crosstalk between antiviral response and cancerous pathways via extracellular vesicles in HIV-1-associated colorectal cancer.
Chen Z, Yang K, Zhang J, Ren S, Chen H, Guo J, Cui Y, Wang T, Wang M
Computational and structural biotechnology journal 2023;21:3369-3382
Computational and structural biotechnology journal 2023;21:3369-3382
Mesenchymal Stem Cells Inhibit Epithelial-to-Mesenchymal Transition by Modulating the IRE1α Branch of the Endoplasmic Reticulum Stress Response.
Luo R, Wei Y, Chen P, Zhang J, Wang L, Wang W, Wang P, Tian W
Stem cells international 2023;2023:4483776
Stem cells international 2023;2023:4483776
Resveratrol Suppresses Bupivacaine-Induced Spinal Neurotoxicity in Rats by Inhibiting Endoplasmic Reticulum Stress via SIRT1 Modulation.
Luo Y, Zhao Y, Lai J, Wei L, Zhou G, Yu Y, Liu J
BioMed research international 2023;2023:1176232
BioMed research international 2023;2023:1176232
Quantitative Measurement of Transthyretin Mistargeting by Proximity Labeling and Parallel Reaction Monitoring.
Lyu Z, Genereux JC
Frontiers in chemical biology 2023;2
Frontiers in chemical biology 2023;2
ER translocon inhibitor ipomoeassin F inhibits triple-negative breast cancer growth via blocking ER molecular chaperones.
Tao S, Yang EJ, Zong G, Mou PK, Ren G, Pu Y, Chen L, Kwon HJ, Zhou J, Hu Z, Khosravi A, Zhang Q, Du Y, Shi WQ, Shim JS
International journal of biological sciences 2023;19(13):4020-4035
International journal of biological sciences 2023;19(13):4020-4035
miR-199a-5p inhibits aortic valve calcification by targeting ATF6 and GRP78 in valve interstitial cells.
Chu H, Fan X, Zhang Z, Han L
Open medicine (Warsaw, Poland) 2023;18(1):20230777
Open medicine (Warsaw, Poland) 2023;18(1):20230777
Exogenous Hydrogen Sulfide Induces A375 Melanoma Cell Apoptosis Through Overactivation of the Unfolded Protein Response.
Ma W, Zhang X, Zhuang L
Clinical, cosmetic and investigational dermatology 2023;16:1641-1651
Clinical, cosmetic and investigational dermatology 2023;16:1641-1651
Direct interaction of the molecular chaperone GRP78/BiP with the Newcastle disease virus hemagglutinin-neuraminidase protein plays a vital role in viral attachment to and infection of culture cells.
Han C, Xie Z, Lv Y, Liu D, Chen R
Frontiers in immunology 2023;14:1259237
Frontiers in immunology 2023;14:1259237
Heterologous DNA-prime/protein-boost immunization with a monomeric SARS-CoV-2 spike antigen redundantizes the trimeric receptor-binding domain structure to induce neutralizing antibodies in old mice.
Pflumm D, Seidel A, Klein F, Groß R, Krutzke L, Kochanek S, Kroschel J, Münch J, Stifter K, Schirmbeck R
Frontiers in immunology 2023;14:1231274
Frontiers in immunology 2023;14:1231274
Chrysin ameliorates synovitis and fibrosis of osteoarthritic fibroblast-like synoviocytes in rats through PERK/TXNIP/NLRP3 signaling.
Ding L, Liao T, Yang N, Wei Y, Xing R, Wu P, Li X, Mao J, Wang P
Frontiers in pharmacology 2023;14:1170243
Frontiers in pharmacology 2023;14:1170243
Transcriptomics reveals the effects of NTRK1 on endoplasmic reticulum stress response-associated genes in human neuronal cell lines.
Jiao B, Zhang M, Zhang C, Cao X, Liu B, Li N, Sun J, Zhang X
PeerJ 2023;11:e15219
PeerJ 2023;11:e15219
HMMR alleviates endoplasmic reticulum stress by promoting autophagolysosomal activity during endoplasmic reticulum stress-driven hepatocellular carcinoma progression.
He L, Li H, Li C, Liu ZK, Lu M, Zhang RY, Wu D, Wei D, Shao J, Liu M, Wei HL, Zhang C, Wang Z, Kong LM, Chen ZN, Bian H
Cancer communications (London, England) 2023 Sep;43(9):981-1002
Cancer communications (London, England) 2023 Sep;43(9):981-1002
Resveratrol‑mediated activation of SIRT1 inhibits the PERK‑eIF2α‑ATF4 pathway and mitigates bupivacaine‑induced neurotoxicity in PC12 cells.
Luo Y, Hu N, Zhao Y, Lai J, Luo X, Liu J
Experimental and therapeutic medicine 2023 Sep;26(3):433
Experimental and therapeutic medicine 2023 Sep;26(3):433
Estrogens drive the endoplasmic reticulum-associated degradation and promote proto-oncogene c-Myc expression in prostate cancer cells by androgen receptor/estrogen receptor signaling.
Erzurumlu Y, Dogan HK, Catakli D, Aydogdu E, Muhammed MT
Journal of cell communication and signaling 2023 Sep;17(3):793-811
Journal of cell communication and signaling 2023 Sep;17(3):793-811
Deubiquitinase USP19 modulates apoptotic calcium release and endoplasmic reticulum stress by deubiquitinating BAG6 in triple negative breast cancer.
Zhang X, Chen X, Qian F, Zhu Y, He G, Yang J, Wu X, Zhang H, Yu X, Liu X
Clinical and translational medicine 2023 Sep;13(9):e1398
Clinical and translational medicine 2023 Sep;13(9):e1398
Triiodothyronine positively regulates endoplasmic reticulum-associated degradation (ERAD) and promotes androgenic signaling in androgen-dependent prostate cancer cells.
Erzurumlu Y, Muhammed MT
Cellular signalling 2023 Sep;109:110745
Cellular signalling 2023 Sep;109:110745
Large HBV Surface Protein-Induced Unfolded Protein Response Dynamically Regulates p27 Degradation in Hepatocellular Carcinoma Progression.
Guo Y, Shao J, Zhang R, Han M, Kong L, Liu Z, Li H, Wei D, Lu M, Zhang S, Zhang C, Wei H, Chen Z, Bian H
International journal of molecular sciences 2023 Sep 7;24(18)
International journal of molecular sciences 2023 Sep 7;24(18)
Down-regulation of Hrd1 protects against myocardial ischemia-reperfusion injury by regulating PPARα to prevent oxidative stress, endoplasmic reticulum stress, and cellular apoptosis.
Xia B, Li Q, Zheng K, Wu J, Huang C, Liu K, You Q, Yuan X
European journal of pharmacology 2023 Sep 5;954:175864
European journal of pharmacology 2023 Sep 5;954:175864
Exogenous spermidine alleviates diabetic cardiomyopathy via suppressing reactive oxygen species, endoplasmic reticulum stress, and Pannexin-1-mediated ferroptosis.
Sun J, Xu J, Liu Y, Lin Y, Wang F, Han Y, Zhang S, Gao X, Xu C, Yuan H
Biomolecules & biomedicine 2023 Sep 4;23(5):825-837
Biomolecules & biomedicine 2023 Sep 4;23(5):825-837
CD44 correlates with longevity and enhances basal ATF6 activity and ER stress resistance.
Takasugi M, Ohtani N, Takemura K, Emmrich S, Zakusilo FT, Yoshida Y, Kutsukake N, Mariani JN, Windrem MS, Chandler-Militello D, Goldman SA, Satoh J, Ito S, Seluanov A, Gorbunova V
Cell reports 2023 Sep 26;42(9):113130
Cell reports 2023 Sep 26;42(9):113130
TSWIFT, a novel method for iterative staining of embedded and mounted human brain sections.
Porter CM, Truttmann MC
bioRxiv : the preprint server for biology 2023 Sep 22;
bioRxiv : the preprint server for biology 2023 Sep 22;
EP300 promotes ferroptosis via HSPA5 acetylation in pancreatic cancer.
Wang Y, Liu Y, Wang C, Kang R, Tang D, Liu J
Scientific reports 2023 Sep 11;13(1):15004
Scientific reports 2023 Sep 11;13(1):15004
Activation of endoplasmic reticulum stress by harmine suppresses the growth of esophageal squamous cell carcinoma.
Fan R, Wang S, Wu Y, Feng Y, Gao M, Cao Y, Ma X, Xie S, Wang C, Gao L, Wang Y, Dai F
Phytotherapy research : PTR 2023 Oct;37(10):4655-4673
Phytotherapy research : PTR 2023 Oct;37(10):4655-4673
Cucurbitacin B induces apoptosis in colorectal cells through reactive oxygen species generation and endoplasmic reticulum stress pathways.
Huang JL, Liang L, Xie PE, Sun WL, Wang L, Cai ZW
Experimental and therapeutic medicine 2023 Oct;26(4):484
Experimental and therapeutic medicine 2023 Oct;26(4):484
SARS-COV-2 spike protein promotes RPE cell senescence via the ROS/P53/P21 pathway.
Zhang Y, Peng X, Xue M, Liu J, Shang G, Jiang M, Chen D, Liu B, Wang Y, Jia X, Xu J, Zhang F, Hu Y
Biogerontology 2023 Oct;24(5):813-827
Biogerontology 2023 Oct;24(5):813-827
Exposure to nonylphenol in early life causes behavioural deficits related with autism spectrum disorders in rats.
You M, Li S, Yan S, Yao D, Wang T, Wang Y
Environment international 2023 Oct;180:108228
Environment international 2023 Oct;180:108228
Ginsenoside F4 Alleviates Skeletal Muscle Insulin Resistance by Regulating PTP1B in Type II Diabetes Mellitus.
Zhao Y, Liu Y, Deng J, Zhu C, Ma X, Jiang M, Fan D
Journal of agricultural and food chemistry 2023 Oct 4;71(39):14263-14275
Journal of agricultural and food chemistry 2023 Oct 4;71(39):14263-14275
Afzelin induces immunogenic cell death against lung cancer by targeting NQO2.
Xia L, Xu X, Li M, Zhang X, Cao F
BMC complementary medicine and therapies 2023 Oct 27;23(1):381
BMC complementary medicine and therapies 2023 Oct 27;23(1):381
Acute Endoplasmic Reticulum Stress Suppresses Hepatic Gluconeogenesis by Stimulating MAPK Phosphatase 3 Degradation.
Huang X, Zhu H, Lu W, Cao L, Fang Z, Che L, Lin Y, Xu S, Zhuo Y, Hua L, Jiang X, Sun M, Wu D, Feng B
International journal of molecular sciences 2023 Oct 25;24(21)
International journal of molecular sciences 2023 Oct 25;24(21)
Metformin inhibits inflammatory response and endoplasmic reticulum stress to improve hypothalamic aging in obese mice.
Yang L, Lu P, Qi X, Yang Q, Liu L, Dou T, Guan Q, Yu C
iScience 2023 Oct 20;26(10):108082
iScience 2023 Oct 20;26(10):108082
MANF stimulates autophagy and restores mitochondrial homeostasis to treat autosomal dominant tubulointerstitial kidney disease in mice.
Kim Y, Li C, Gu C, Fang Y, Tycksen E, Puri A, Pietka TA, Sivapackiam J, Kidd K, Park SJ, Johnson BG, Kmoch S, Duffield JS, Bleyer AJ, Jackrel ME, Urano F, Sharma V, Lindahl M, Chen YM
Nature communications 2023 Oct 14;14(1):6493
Nature communications 2023 Oct 14;14(1):6493
Combination therapy with HSP90 inhibitors and piperlongumine promotes ROS-mediated ER stress in colon cancer cells.
Qiu C, Shen X, Lu H, Chen Y, Xu C, Zheng P, Xia Y, Wang J, Zhang Y, Li S, Zou P, Cui R, Chen J
Cell death discovery 2023 Oct 13;9(1):375
Cell death discovery 2023 Oct 13;9(1):375
Role of SIRT2 in intestinal barrier under cold exposure.
Guo J, Xu J, Chen L, Chen Z, Hu H, Nie J, Yuan J, Ma L, Lu J, Ji H, Xu B
Life sciences 2023 Oct 1;330:121949
Life sciences 2023 Oct 1;330:121949
Key Subdomains of Cerebral Dopamine Neurotrophic Factor Regulate Its Protective Function in 6-Hydroxydopamine-Lesioned PC12 Cells.
Liu H, Dong H, Wang C, Jia W, Wang G, Wang H, Zhong L, Gong L
DNA and cell biology 2023 Nov;42(11):680-688
DNA and cell biology 2023 Nov;42(11):680-688
Fusaric acid inhibits proliferation and induces apoptosis through triggering endoplasmic reticulum stress in MCF-7 human breast cancer cells.
Zhang J, Yuan H, Li W, Chen S, Liu S, Li C, Yao X
Mycotoxin research 2023 Nov;39(4):347-364
Mycotoxin research 2023 Nov;39(4):347-364
LIMK1 m(6)A-RNA methylation recognized by YTHDC2 induces 5-FU chemoresistance in colorectal cancer via endoplasmic reticulum stress and stress granule formation.
Chen L, Sun K, Qin W, Huang B, Wu C, Chen J, Lai Q, Wang X, Zhou R, Li A, Liu S, Zhang Y
Cancer letters 2023 Nov 1;576:216420
Cancer letters 2023 Nov 1;576:216420
Cryptotanshinone induces apoptosis of activated hepatic stellate cells via modulating endoplasmic reticulum stress.
Hou XX, Li YW, Song JL, Zhang W, Liu R, Yuan H, Feng TT, Jiang ZY, Li WT, Zhu CL
World journal of gastroenterology 2023 May 7;29(17):2616-2627
World journal of gastroenterology 2023 May 7;29(17):2616-2627
Vitamin K-dependent carboxylation regulates Ca(2+) flux and adaptation to metabolic stress in β cells.
Lacombe J, Guo K, Bonneau J, Faubert D, Gioanni F, Vivoli A, Muir SM, Hezzaz S, Poitout V, Ferron M
Cell reports 2023 May 30;42(5):112500
Cell reports 2023 May 30;42(5):112500
Salvianolic acid A attenuates inflammation-mediated atherosclerosis by suppressing GRP78 secretion of endothelial cells.
Fan X, Zhang L, La X, Tian J, Israr G, Li A, Wu C, An Y, Li S, Dong X, Li Z
Journal of ethnopharmacology 2023 May 23;308:116219
Journal of ethnopharmacology 2023 May 23;308:116219
Role of selenoprotein M knockdown in the melatonin antagonism of nickel-induced apoptosis and endoplasmic reticulum stress in mouse heart.
Zhang X, Gai X, Xu L, Ma W, Liu Q, Shi B, Fang C, Cai J, Zhang Z
Journal of Zhejiang University. Science. B 2023 May 15;24(5):406-417
Journal of Zhejiang University. Science. B 2023 May 15;24(5):406-417
Pathological convergence of APP and SNCA deficiency in hippocampal degeneration of young rats.
Wang Y, Miao Z, Xu C, Cai Y, Yang Y, Hu Y, Zhao M, Shao Y, Li Z, Chen J, Chen S, Wang L
Cell death & disease 2023 May 13;14(5):325
Cell death & disease 2023 May 13;14(5):325
Vitamin D receptor attenuate ischemia-reperfusion kidney injury via inhibiting ATF4.
Tang S, Wu X, Dai Q, Li Z, Yang S, Liu Y, Yi B, Wang J, Liao Q, Zhang W, Zhang H
Cell death discovery 2023 May 12;9(1):158
Cell death discovery 2023 May 12;9(1):158
Endoplasmic reticulum stress promotes sepsis-induced muscle atrophy via activation of STAT3 and Smad3.
Zheng Y, Dai H, Chen R, Zhong Y, Zhou C, Wang Y, Zhan C, Luo J
Journal of cellular physiology 2023 Mar;238(3):582-596
Journal of cellular physiology 2023 Mar;238(3):582-596
Porcine reproductive and respiratory syndrome virus infection triggers autophagy via ER stress-induced calcium signaling to facilitate virus replication.
Diao F, Jiang C, Sun Y, Gao Y, Bai J, Nauwynck H, Wang X, Yang Y, Jiang P, Liu X
PLoS pathogens 2023 Mar;19(3):e1011295
PLoS pathogens 2023 Mar;19(3):e1011295
1,25(OH)(2) D(3) induced vitamin D receptor signaling negatively regulates endoplasmic reticulum-associated degradation (ERAD) and androgen receptor signaling in human prostate cancer cells.
Erzurumlu Y, Aydogdu E, Dogan HK, Catakli D, Muhammed MT, Buyuksandic B
Cellular signalling 2023 Mar;103:110577
Cellular signalling 2023 Mar;103:110577
JQ-1/bortezomib combination strongly impairs MM and PEL survival by inhibiting c-Myc and mTOR despite the activation of prosurvival mechanisms.
Arena A, Romeo MA, Benedetti R, Gilardini Montani MS, Cirone M
Experimental hematology 2023 Mar-Apr;119-120:28-41
Experimental hematology 2023 Mar-Apr;119-120:28-41
HSPA5 Promotes the Proliferation, Metastasis and Regulates Ferroptosis of Bladder Cancer.
Wang Q, Ke S, Liu Z, Shao H, He M, Guo J
International journal of molecular sciences 2023 Mar 7;24(6)
International journal of molecular sciences 2023 Mar 7;24(6)
Porcine Epidemic Diarrhea Virus and Its nsp14 Suppress ER Stress Induced GRP78.
Zeng W, Ren J, Yang G, Jiang C, Dong L, Sun Q, Hu Y, Li W, He Q
International journal of molecular sciences 2023 Mar 3;24(5)
International journal of molecular sciences 2023 Mar 3;24(5)
Potent carotenoid astaxanthin expands the anti-cancer activity of cisplatin in human prostate cancer cells.
Erzurumlu Y, Catakli D, Dogan HK
Journal of natural medicines 2023 Jun;77(3):572-583
Journal of natural medicines 2023 Jun;77(3):572-583
Atorvastatin prevents endoplasmic reticulum stress-mediated apoptosis via the Nrf2/HO-1 signaling pathway in TBI mice.
Feng Y, Lang J, Sun B, Yan Z, Zhao Z, Sun G
Neurological research 2023 Jun;45(6):590-602
Neurological research 2023 Jun;45(6):590-602
Naringin regulates endoplasmic reticulum stress and mitophagy through the ATF3/PINK1 signaling axis to alleviate pulmonary fibrosis.
Wei Y, Sun L, Liu C, Li L
Naunyn-Schmiedeberg's archives of pharmacology 2023 Jun;396(6):1155-1169
Naunyn-Schmiedeberg's archives of pharmacology 2023 Jun;396(6):1155-1169
Developmental growth plate cartilage formation suppressed by artificial light at night via inhibiting BMAL1-driven collagen hydroxylation.
Chen G, Tang Q, Yu S, Shen Y, Sun J, Peng J, Yin Y, Feng G, Lu X, Mei G, Zhang Y, Wan Q, Zhang L, Chen L
Cell death and differentiation 2023 Jun;30(6):1503-1516
Cell death and differentiation 2023 Jun;30(6):1503-1516
Excessive ER-phagy contributes to ochratoxin A-induced apoptosis.
Deng H, Chen W, Zhang B, Zhang Y, Han L, Zhang Q, Yao S, Wang H, Shen XL
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jun;176:113793
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jun;176:113793
HSPA5 Promotes Attachment and Internalization of Porcine Epidemic Diarrhea Virus through Interaction with the Spike Protein and the Endo-/Lysosomal Pathway.
Zhou C, Liu Y, Wei Q, Chen Y, Yang S, Cheng A, Zhang G
Journal of virology 2023 Jun 29;97(6):e0054923
Journal of virology 2023 Jun 29;97(6):e0054923
Discovery of an OTUD3 inhibitor for the treatment of non-small cell lung cancer.
Zhang Y, Du T, Liu N, Wang J, Zhang L, Cui CP, Li C, Zhang X, Wu B, Zhang J, Jiang W, Zhang Y, Zhang Y, Li H, Li P
Cell death & disease 2023 Jun 27;14(6):378
Cell death & disease 2023 Jun 27;14(6):378
Disturbance of neuron-microglia crosstalk mediated by GRP78 in Neuropsychiatric systemic lupus erythematosus mice.
Xu J, Yang C, Zeng S, Wang X, Yang P, Qin L
Journal of neuroinflammation 2023 Jun 26;20(1):150
Journal of neuroinflammation 2023 Jun 26;20(1):150
[Cordycepin, a metabolite of Cordyceps militaris, inhibits xenograft tumor growth of tongue squamous cell carcinoma in nude mice].
Zheng Q, Shao Y, Zheng W, Zou Y
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2023 Jun 20;43(6):873-878
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2023 Jun 20;43(6):873-878
HSF4 Transcriptionally Activates Autophagy by Regulating ATG9a During Lens Terminal Differentiation.
Zhang J, Jiang N, Du C, Guo H, Meng R, Hou X, Liu M, Hu Y, Cui X
Investigative ophthalmology & visual science 2023 Jun 1;64(7):5
Investigative ophthalmology & visual science 2023 Jun 1;64(7):5
Dexamethasone-stimulated glucocorticoid receptor signaling positively regulates the endoplasmic reticulum-associated degradation (ERAD) mechanism in hepatocellular carcinoma cells.
Erzurumlu Y, Dogan HK, Cataklı D
Steroids 2023 Jul;195:109238
Steroids 2023 Jul;195:109238
Betulinic acid mitigates zearalenone-induced liver injury by ERS/MAPK/Nrf2 signaling pathways in mice.
Wu J, Li J, Wu Y, Yang M, Chen Y, Wang N, Wang J, Yuan Z, Yi J, Yang C
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jul;177:113811
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jul;177:113811
Coffee prevents IQ-induced liver damage by regulating oxidative stress, inflammation, endoplasmic reticulum stress, autophagy, apoptosis, and the MAPK/NF-κB signaling pathway in zebrafish.
Li D, Li Z, Dong L, Zhang Y, Lu Y, Wang J, Sun H, Wang S
Food research international (Ottawa, Ont.) 2023 Jul;169:112946
Food research international (Ottawa, Ont.) 2023 Jul;169:112946
Xylanase improves the intestinal barrier function of Nile tilapia (Oreochromis niloticus) fed with soybean (Glycine max) meal.
Wang T, Zhou N, He J, Hao Z, Zhou C, Du Y, Du Z, Su X, Zhang M
Journal of animal science and biotechnology 2023 Jul 7;14(1):86
Journal of animal science and biotechnology 2023 Jul 7;14(1):86
Extracellular HSPA5 is autocrinally involved in the regulation of neuronal process elongation.
Fukawa M, Shirai R, Torii T, Nakata K, Fukatsu S, Sato T, Homma K, Miyamoto Y, Yamauchi J
Biochemical and biophysical research communications 2023 Jul 5;664:50-58
Biochemical and biophysical research communications 2023 Jul 5;664:50-58
Marchf6 E3 ubiquitin ligase critically regulates endoplasmic reticulum stress, ferroptosis, and metabolic homeostasis in POMC neurons.
Mun SH, Lee CS, Kim HJ, Kim J, Lee H, Yang J, Im SH, Kim JH, Seong JK, Hwang CS
Cell reports 2023 Jul 25;42(7):112746
Cell reports 2023 Jul 25;42(7):112746
Therapeutic hyperthermia regulates complement C3 activation and suppresses tumor development through HSPA5/NFκB/CD55 pathway in nasopharyngeal carcinoma.
Chen C, Ren A, Yi Q, Cai J, Khan M, Lin Y, Huang Z, Lin J, Zhang J, Liu W, Xu A, Tian Y, Yuan Y, Zheng R
Clinical and experimental immunology 2023 Jul 21;213(2):221-234
Clinical and experimental immunology 2023 Jul 21;213(2):221-234
Endoplasmic Reticulum Stress Mediated NLRP3 Inflammasome Activation and Pyroptosis in THP-1 Macrophages Infected with Bacillus Calmette-Guérin.
Nie X, Ma B, Liu L, Yuan X, Li M, Liu Y, Hou Y, Yang Y, Xu J, Wang Y
International journal of molecular sciences 2023 Jul 20;24(14)
International journal of molecular sciences 2023 Jul 20;24(14)
Quantitative Measurement of Secretory Protein Mistargeting by Proximity Labeling and Parallel Reaction Monitoring.
Lyu Z, Genereux JC
bioRxiv : the preprint server for biology 2023 Jul 20;
bioRxiv : the preprint server for biology 2023 Jul 20;
Hypothermic oxygenated perfusion attenuates DCD liver ischemia-reperfusion injury by activating the JAK2/STAT3/HAX1 pathway to regulate endoplasmic reticulum stress.
Yue P, Lv X, You J, Zou Y, Luo J, Lu Z, Cao H, Liu Z, Fan X, Ye Q
Cellular & molecular biology letters 2023 Jul 12;28(1):55
Cellular & molecular biology letters 2023 Jul 12;28(1):55
AGO4 suppresses tumor growth by modulating autophagy and apoptosis via enhancing TRIM21-mediated ubiquitination of GRP78 in a p53-independent manner.
Wang L, Li D, Su X, Zhao Y, Huang A, Li H, Li J, Xia W, Jia T, Zhang H, Dong J, Liu X, Shao N
Oncogene 2023 Jan;42(1):62-77
Oncogene 2023 Jan;42(1):62-77
Treponema pallidum lipoprotein Tp0768 promotes the migration and adhesion of THP-1 cells to vascular endothelial cells through stress of the endoplasmic reticulum and the NF-κB/HIF-1α pathway.
Zhou X, Tang Y, Cao T, Ning L, Li Y, Xie X, Hu Y, He B, Peng B, Liu S
Molecular microbiology 2023 Jan;119(1):86-100
Molecular microbiology 2023 Jan;119(1):86-100
Glucotropaeolin Promotes Apoptosis by Calcium Dysregulation and Attenuates Cell Migration with FOXM1 Suppression in Pancreatic Cancer Cells.
Lee W, Song G, Bae H
Antioxidants (Basel, Switzerland) 2023 Jan 23;12(2)
Antioxidants (Basel, Switzerland) 2023 Jan 23;12(2)
Signal sequences encode information for protein folding in the endoplasmic reticulum.
Sun S, Li X, Mariappan M
The Journal of cell biology 2023 Jan 2;222(1)
The Journal of cell biology 2023 Jan 2;222(1)
Discovery of rafoxanide as a novel agent for the treatment of non-small cell lung cancer.
Hu A, Liu J, Wang Y, Zhang M, Guo Y, Qin Y, Liu T, Men Y, Chen Q, Liu T
Scientific reports 2023 Jan 13;13(1):693
Scientific reports 2023 Jan 13;13(1):693
Silica nanoparticles aggravated the metabolic associated fatty liver disease through disturbed amino acid and lipid metabolisms-mediated oxidative stress.
Abulikemu A, Zhao X, Xu H, Li Y, Ma R, Yao Q, Wang J, Sun Z, Li Y, Guo C
Redox biology 2023 Feb;59:102569
Redox biology 2023 Feb;59:102569
Progesterone regulates the endoplasmic reticulum-associated degradation and Unfolded Protein Response axis by mimicking the androgenic stimulation in prostate cancer cells.
Erzurumlu Y, Dogan HK, Catakli D
Molecular biology reports 2023 Feb;50(2):1253-1265
Molecular biology reports 2023 Feb;50(2):1253-1265
ADP-ribose transferase PARP16 mediated-unfolded protein response contributes to neuronal cell damage in cerebral ischemia/reperfusion.
Wang J, Xu J, Dong Y, Su Z, Su H, Cheng Q, Liu X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Feb;37(2):e22788
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Feb;37(2):e22788
Jianpi-Qingchang decoction alleviates ulcerative colitis by modulating endoplasmic reticulum stress-related autophagy in intestinal epithelial cells.
Qiao D, Liu X, Zhang Y, Zhang Z, Tang Y, Chen Q, Shi Y, Chen Y, Tang Z, Dai Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Feb;158:114133
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Feb;158:114133
Citrus peel ameliorates mucus barrier damage in HFD-fed mice.
Han P, Yu Y, Zhang L, Ruan Z
The Journal of nutritional biochemistry 2023 Feb;112:109206
The Journal of nutritional biochemistry 2023 Feb;112:109206
A quantitative proteomic analyses of primary myocardial cell injury induced by heat stress in chicken embryo.
Wang R, Guo Y, Shi Z, Qin S
Journal of thermal biology 2023 Feb;112:103461
Journal of thermal biology 2023 Feb;112:103461
Non-Lethal Concentrations of CdCl(2) Cause Marked Alternations in Cellular Stress Responses within Exposed Sertoli Cell Line.
Man Y, Liu Y, Xiong C, Zhang Y, Zhang L
Toxics 2023 Feb 9;11(2)
Toxics 2023 Feb 9;11(2)
Methyltransferase-like 3 aggravates endoplasmic reticulum stress in preeclampsia by targeting TMBIM6 in YTHDF2-dependent manner.
Chen Y, Liu X, Li L, He X, Zheng F, Zhang Y, Gao H, Jin Z, Wu D, Wang Q, Tao H, Zhao Y, Liu W, Zou L
Molecular medicine (Cambridge, Mass.) 2023 Feb 6;29(1):19
Molecular medicine (Cambridge, Mass.) 2023 Feb 6;29(1):19
Tunicamycin induces depression-like behaviors in male rats, accompanied by initiated chaperon-mediated autophagy and decreased synaptic protein expression in the hippocampus.
Yuan G, Xiao L, Xie Y, Si L, Xu H, Xu W, Wang G
Neuroscience letters 2023 Feb 28;798:137058
Neuroscience letters 2023 Feb 28;798:137058
Mitochondrial SENP2 regulates the assembly of SDH complex under metabolic stress.
Liu Y, Liu K, Thorne RF, Shi R, Zhang Q, Wu M, Liu L
Cell reports 2023 Feb 28;42(2):112041
Cell reports 2023 Feb 28;42(2):112041
Polystyrene Microplastics Induced Ovarian Toxicity in Juvenile Rats Associated with Oxidative Stress and Activation of the PERK-eIF2α-ATF4-CHOP Signaling Pathway.
Wang W, Guan J, Feng Y, Liu S, Zhao Y, Xu Y, Xu H, Fu F
Toxics 2023 Feb 27;11(3)
Toxics 2023 Feb 27;11(3)
NRF2 and Bip Interconnection Mediates Resistance to the Organometallic Ruthenium-Cymene Bisdemethoxycurcumin Complex Cytotoxicity in Colon Cancer Cells.
Garufi A, Pettinari R, Marchetti F, Cirone M, D'Orazi G
Biomedicines 2023 Feb 16;11(2)
Biomedicines 2023 Feb 16;11(2)
Decreased syntaxin17 expression contributes to the pathogenesis of acute pancreatitis in murine models by impairing autophagic degradation.
Wang TT, Zhang LC, Qin Z, Chen SJ, Zeng JM, Li JY, An L, Wang CY, Gao Y, Wang LM, Zhao ZX, Liu ZQ, Wang SG
Acta pharmacologica Sinica 2023 Dec;44(12):2445-2454
Acta pharmacologica Sinica 2023 Dec;44(12):2445-2454
Lithium chloride induces apoptosis by activating endoplasmic reticulum stress in pancreatic cancer.
Wu H, Zhang Y, Liang J, Wu J, Zhang Y, Su H, Zhang Q, Shen Y, Shen S, Wang L, Zou X, Hang C, Zhang S, Lv Y
Translational oncology 2023 Dec;38:101792
Translational oncology 2023 Dec;38:101792
EIF2α/ATF4 pathway enhances proliferation of mesangial cell via cyclin D1 during endoplasmic reticulum stress in IgA nephropathy.
Lan Z, Zhao L, Peng L, Wan L, Liu D, Tang C, Chen G, Liu Y, Liu H
Clinical immunology (Orlando, Fla.) 2023 Dec;257:109840
Clinical immunology (Orlando, Fla.) 2023 Dec;257:109840
Exogenous H(2) S promotes ubiquitin-mediated degradation of SREBP1 to alleviate diabetic cardiomyopathy via SYVN1 S-sulfhydration.
Zhang S, Wang M, Li H, Li Q, Liu N, Dong S, Zhao Y, Pang K, Huang J, Ren C, Wang Y, Tian Z, Lu F, Zhang W
Journal of cachexia, sarcopenia and muscle 2023 Dec;14(6):2719-2732
Journal of cachexia, sarcopenia and muscle 2023 Dec;14(6):2719-2732
An investigation of the endoplasmic reticulum stress in obesity exposure in the prenatal period.
Tüfekci KK, Tatar M, Terzi F, Bakirhan EG
Journal of chemical neuroanatomy 2023 Dec;134:102348
Journal of chemical neuroanatomy 2023 Dec;134:102348
Lead and cadmium co-exposure modified PC12 viability and ER stress: study from a 3 × 3 factorial design.
Su X, Wang R, Wu Y, Yang M, Ba Y, Huang H
Toxicology research 2023 Dec;12(6):1135-1142
Toxicology research 2023 Dec;12(6):1135-1142
Nutrient deprivation alters the rate of COPII subunit recruitment at ER subdomains to tune secretory protein transport.
Kasberg W, Luong P, Swift KA, Audhya A
Nature communications 2023 Dec 8;14(1):8140
Nature communications 2023 Dec 8;14(1):8140
NTRK1-mediated protection against manganese-induced neurotoxicity and cell apoptosis via IGF2 in SH-SY5Y cells.
Zhang C, Jiao B, Cao X, Zhang W, Yu S, Zhang K, Zhang M, Zhang X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec 31;169:115889
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec 31;169:115889
Role of SYVN1 in the control of airway remodeling in asthma protection by promoting SIRT2 ubiquitination and degradation.
Dai B, Liu S, Shen W, Chen L, Zhou Q, Han L, Zhang Q, Shan L
Biological research 2023 Dec 2;56(1):64
Biological research 2023 Dec 2;56(1):64
Corilagin enhances the anti-tumor activity of 5-FU by downregulating the expression of GRP 78.
Li S, Li X, Yang X, Lei Y, He M, Xiang X, Wu Q, Liu H, Wang J, Wang Q
Scientific reports 2023 Dec 19;13(1):22661
Scientific reports 2023 Dec 19;13(1):22661
ER Stress-Perturbed Intracellular Protein O-GlcNAcylation Aggravates Podocyte Injury in Diabetes Nephropathy.
Song S, Hu T, Shi X, Jin Y, Liu S, Li X, Zou W, Wang C
International journal of molecular sciences 2023 Dec 18;24(24)
International journal of molecular sciences 2023 Dec 18;24(24)
Glycyrrhetinic acid attenuates endoplasmic reticulum stress-induced hepatocyte apoptosis via CHOP/DR5/Caspase 8 pathway in cholestasis.
Zou B, Zhang S, Zhao J, Song G, Weng F, Xu X, Li F, Jin J, Yan D, Huang K, Liu C, Li Y, Qiu F
European journal of pharmacology 2023 Dec 15;961:176193
European journal of pharmacology 2023 Dec 15;961:176193
Reduced Proteolipid Protein 2 promotes endoplasmic reticulum stress-related apoptosis and increases drug sensitivity in acute myeloid leukemia.
Xie F, Qu J, Lin D, Feng K, Tan M, Liao H, Zeng L, Xiong Q, Huang J, Chen W
Molecular biology reports 2023 Dec 12;51(1):10
Molecular biology reports 2023 Dec 12;51(1):10
XBP1s gene of endoplasmic reticulum stress enhances proliferation and osteogenesis of human periodontal ligament cells.
Cui Z, Qin R, Feng J, Liu Y, Zhou X, Qin X, Li Y, Zhang Z, He X
Tissue & cell 2023 Aug;83:102139
Tissue & cell 2023 Aug;83:102139
The therapeutic effect of tanshinone IIA in mouse astrocytes after treatment with Angiostrongylus cantonensis fifth-stage larval excretory-secretory products.
Chen KY, Chen YJ, Cheng CJ, Jhan KY, Chiu CH, Wang LC
Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi 2023 Aug;56(4):853-862
Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi 2023 Aug;56(4):853-862
Dipyridamole enhances the anti-cancer ability of aspirin against colorectal cancer by inducing apoptosis in an unfolded protein response-dependent manner.
Huang S, Zhang NQ, Xu CJ, Huang WQ, Li DX, Li J, Yao LL, Sundquist K, Sundquist J, Jiang SH, Xing X, Hu LP, Zhang ZG, Ji J, Zhang XL
Cellular oncology (Dordrecht, Netherlands) 2023 Aug;46(4):953-967
Cellular oncology (Dordrecht, Netherlands) 2023 Aug;46(4):953-967
RCN2 promotes Nasopharyngeal carcinoma progression by curbing Calcium flow and Mitochondrial apoptosis.
Yao H, Zhang S, Xie H, Fan Y, Miao M, Zhu R, Yuan L, Gu M, You Y, You B
Cellular oncology (Dordrecht, Netherlands) 2023 Aug;46(4):1031-1048
Cellular oncology (Dordrecht, Netherlands) 2023 Aug;46(4):1031-1048
LINC00355 Mediates CTNNBIP1 Promoter Methylation and Promotes Endoplasmic Reticulum Stress-Induced Podocyte Injury in Diabetic Nephropathy.
Zhang T, Zhang Y, Xu H, Lan J, Feng Z, Huang R, Geng J, Chi H, Bai X
Antioxidants & redox signaling 2023 Aug;39(4-6):225-240
Antioxidants & redox signaling 2023 Aug;39(4-6):225-240
Exogenous hydrogen sulfide alleviates hepatic endoplasmic reticulum stress via SIRT1/FoxO1/PCSK9 pathway in NAFLD.
Cui X, Yao M, Feng Y, Li C, Li Y, Guo D, He S
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Aug;37(8):e23027
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Aug;37(8):e23027
Tanshinone IIA ameliorates experimental diabetic cardiomyopathy by inhibiting endoplasmic reticulum stress in cardiomyocytes via SIRT1.
Wu S, Lu D, Gajendran B, Hu Q, Zhang J, Wang S, Han M, Xu Y, Shen X
Phytotherapy research : PTR 2023 Aug;37(8):3543-3558
Phytotherapy research : PTR 2023 Aug;37(8):3543-3558
Fluoride-Induced Cortical Toxicity in Rats: the Role of Excessive Endoplasmic Reticulum Stress and Its Mediated Defective Autophagy.
Zhang J, Tang Y, Xu W, Hu Z, Xu S, Niu Q
Biological trace element research 2023 Aug;201(8):3850-3860
Biological trace element research 2023 Aug;201(8):3850-3860
Zinc deficiency causes oxidative stress, endoplasmic reticulum stress, apoptosis and inflammation in hepatocytes in grass carp.
Cui J, Xu T, Lv H, Guo MY
Fish & shellfish immunology 2023 Aug;139:108905
Fish & shellfish immunology 2023 Aug;139:108905
Salidroside ameliorates acetaminophen-induced acute liver injury through the inhibition of endoplasmic reticulum stress-mediated ferroptosis by activating the AMPK/SIRT1 pathway.
Xu J, Zhao L, Zhang X, Ying K, Zhou R, Cai W, Wu X, Jiang H, Xu Q, Miao D, Zeng Y, Yu F
Ecotoxicology and environmental safety 2023 Aug 7;262:115331
Ecotoxicology and environmental safety 2023 Aug 7;262:115331
4-phenylbutyric acid re-trafficking hERG/G572R channel protein by modulating the endoplasmic reticulum stress-associated chaperones and endoplasmic reticulum-associated degradation gene.
Tang W, Cai D, Fu Y, Zheng Z, Huang X, Khouzam RN, Song Y, Lian J
Journal of thoracic disease 2023 Aug 31;15(8):4472-4485
Journal of thoracic disease 2023 Aug 31;15(8):4472-4485
Advanced oxidation protein products induce Paneth cells defects by endoplasmic reticulum stress in Crohn's disease.
Shi J, Wang W, Sun S, Xu X, Fei J, Zhou Q, Qin C, Ou S, Wu F, Wu FT, Xu T, Bai L, Xie F
iScience 2023 Aug 18;26(8):107312
iScience 2023 Aug 18;26(8):107312
PARP1-catalyzed PARylation of YY1 mediates endoplasmic reticulum stress in granulosa cells to determine primordial follicle activation.
Chen W, E Q, Sun B, Zhang P, Li N, Fei S, Wang Y, Liu S, Liu X, Zhang X
Cell death & disease 2023 Aug 15;14(8):524
Cell death & disease 2023 Aug 15;14(8):524
Interaction of Bmal1 and eIF2α/ATF4 pathway was involved in Shuxie compound alleviation of circadian rhythm disturbance-induced hepatic endoplasmic reticulum stress.
Zhang M, Wu W, Huang C, Cai T, Wang M, Zhao N, Liu S, Yang S
Journal of ethnopharmacology 2023 Aug 10;312:116446
Journal of ethnopharmacology 2023 Aug 10;312:116446
PARP16-Mediated Stabilization of Amyloid Precursor Protein mRNA Exacerbates Alzheimer's Disease Pathogenesis.
Wang J, Cheng Q, Zhang Y, Hong C, Liu J, Liu X, Chang J
Aging and disease 2023 Aug 1;14(4):1458-1471
Aging and disease 2023 Aug 1;14(4):1458-1471
Cannabidiol Protects Striatal Neurons by Attenuating Endoplasmic Reticulum Stress.
Patel V, Abu-Hijleh F, Rigg N, Mishra R
Cannabis and cannabinoid research 2023 Apr;8(2):299-308
Cannabis and cannabinoid research 2023 Apr;8(2):299-308
FUT2-dependent fucosylation of HYOU1 protects intestinal stem cells against inflammatory injury by regulating unfolded protein response.
Wang Z, Tan C, Duan C, Wu J, Zhou D, Hou L, Qian W, Han C, Hou X
Redox biology 2023 Apr;60:102618
Redox biology 2023 Apr;60:102618
Low temperature plasma protects against inflammatory agents-mediated dysfunction of theca cells via enhancing MANF expression.
Yu S, Zhang X, Sun T, Wang D, Wei Z
Molecular biology reports 2023 Apr;50(4):3085-3097
Molecular biology reports 2023 Apr;50(4):3085-3097
cFLIP(L) Alleviates Myocardial Ischemia-Reperfusion Injury by Inhibiting Endoplasmic Reticulum Stress.
Li YZ, Wu H, Liu D, Yang J, Yang J, Ding JW, Zhou G, Zhang J, Zhang D
Cardiovascular drugs and therapy 2023 Apr;37(2):225-238
Cardiovascular drugs and therapy 2023 Apr;37(2):225-238
Dihydroartemisinin elicits immunogenic death through ferroptosis-triggered ER stress and DNA damage for lung cancer immunotherapy.
Han N, Yang ZY, Xie ZX, Xu HZ, Yu TT, Li QR, Li LG, Peng XC, Yang XX, Hu J, Xu X, Chen X, Wang MF, Li TF
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Apr;112:154682
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Apr;112:154682
Apurinic/apyrimidinic endonuclease 1 regulates palmitic acid-mediated apoptosis in cardiomyocytes via endoplasmic reticulum stress.
Fan J, Liu M, Li X, Gao S, Wang Y, Li A, Chen L, Zhou D, Chen H, Xu Z, Wu Z, Wu K
Biochemical and biophysical research communications 2023 Apr 2;650:123-131
Biochemical and biophysical research communications 2023 Apr 2;650:123-131
Antitumoral effects of Bortezomib in malignant mesothelioma: evidence of mild endoplasmic reticulum stress in vitro and activation of T cell response in vivo.
Benvenuto M, Angiolini V, Focaccetti C, Nardozi D, Palumbo C, Carrano R, Rufini A, Bei R, Miele MT, Mancini P, Barillari G, Cirone M, Ferretti E, Tundo GR, Mutti L, Masuelli L, Bei R
Biology direct 2023 Apr 17;18(1):17
Biology direct 2023 Apr 17;18(1):17
Citrinin Exposure Induced Testicular Damage and Spermatogenesis Disorder by Triggering Endoplasmic Reticulum Stress.
Wu J, Wu Y, Fan H, Yang C, Yang M, Kong X, Ning C, Wang S, Xiao W, Wang N, Yi J, Yuan Z
Foods (Basel, Switzerland) 2023 Apr 11;12(8)
Foods (Basel, Switzerland) 2023 Apr 11;12(8)
The cervical lymph node contributes to peripheral inflammation related to Parkinson's disease.
Liu Z, Huang Y, Wang X, Li JY, Zhang C, Yang Y, Zhang J
Journal of neuroinflammation 2023 Apr 10;20(1):93
Journal of neuroinflammation 2023 Apr 10;20(1):93
The Mechanism of Lipopolysaccharide Escaping the Intestinal Barrier in Megalobrama amblycephala Fed a High-Fat Diet.
Dai YJ, Liu WB, Abasubong KP, Zhang DD, Li XF, Xiao K, Wang X, Jiang GZ
Frontiers in nutrition 2022;9:853409
Frontiers in nutrition 2022;9:853409
Effects of folic acid on oxidative damage of kidney in lead-exposed rats.
Li N, Wen L, Yu Z, Li T, Wang T, Qiao M, Song L, Huang X
Frontiers in nutrition 2022;9:1035162
Frontiers in nutrition 2022;9:1035162
Jianpi Qingchang Decoction Ameliorates Chronic Colitis in Piroxicam-Induced IL-10 Knockout Mice by Inhibiting Endoplasmic Reticulum Stress.
Chen Q, Zhang YL, Zhang ZW, Chen YJ, Tang YJ, Qiao D, Dai YC, Tang ZP
Evidence-based complementary and alternative medicine : eCAM 2022;2022:7378807
Evidence-based complementary and alternative medicine : eCAM 2022;2022:7378807
HSPA5 Inhibitor Meliorate DSS-Induced Colitis through HSPA1A/CHIP.
Gao F, Fan H, Xue L, Shou Z, Zhu F, Yu T, Chu S, Wei C, Liu C, Zuo D, Zuo D
Disease markers 2022;2022:7115181
Disease markers 2022;2022:7115181
EGCG Enhances the Chemosensitivity of Colorectal Cancer to Irinotecan through GRP78-MediatedEndoplasmic Reticulum Stress.
Wu W, Gou H, Xiang B, Geng R, Dong J, Yang X, Chen D, Dai R, Chen L, Liu J
Journal of oncology 2022;2022:7099589
Journal of oncology 2022;2022:7099589
Naringenin Alleviates Renal Ischemia Reperfusion Injury by Suppressing ER Stress-Induced Pyroptosis and Apoptosis through Activating Nrf2/HO-1 Signaling Pathway.
Zhang B, Wan S, Liu H, Qiu Q, Chen H, Chen Z, Wang L, Liu X
Oxidative medicine and cellular longevity 2022;2022:5992436
Oxidative medicine and cellular longevity 2022;2022:5992436
LARS2 Regulates Apoptosis via ROS-Mediated Mitochondrial Dysfunction and Endoplasmic Reticulum Stress in Ovarian Granulosa Cells.
Feng S, Wan S, Liu S, Wang W, Tang M, Bai L, Zhu Y
Oxidative medicine and cellular longevity 2022;2022:5501346
Oxidative medicine and cellular longevity 2022;2022:5501346
Saikosaponin D Inducing Apoptosis and Autophagy through the Activation of Endoplasmic Reticulum Stress in Glioblastoma.
Liu G, Guan Y, Liu Y, Wang Y, Zhang J, Liu Y, Liu X
BioMed research international 2022;2022:5489553
BioMed research international 2022;2022:5489553
Deletion of ACLY Disrupts Histone Acetylation and IL-10 Secretion in Trophoblasts, Which Inhibits M2 Polarization of Macrophages: A Possible Role in Recurrent Spontaneous Abortion.
Chen X, Song QL, Li ZH, Ji R, Wang JY, Ge C, Xiao ZN, Guo DY, Yang J
Oxidative medicine and cellular longevity 2022;2022:5216786
Oxidative medicine and cellular longevity 2022;2022:5216786
Negative Feedback of the cAMP/PKA Pathway Regulates the Effects of Endoplasmic Reticulum Stress-Induced NLRP3 Inflammasome Activation on Type II Alveolar Epithelial Cell Pyroptosis as a Novel Mechanism of BLM-Induced Pulmonary Fibrosis.
Hong Q, Zhang Y, Lin W, Wang W, Yuan Y, Lin J, Xie Z, Li X, Meng Y
Journal of immunology research 2022;2022:2291877
Journal of immunology research 2022;2022:2291877
Oleoylethanolamide Alleviates Hepatic Ischemia-Reperfusion Injury via Inhibiting Endoplasmic Reticulum Stress-Associated Apoptosis.
Qi S, Yan Q, Wang Z, Liu D, Zhan M, Du J, Chen L
PPAR research 2022;2022:2212996
PPAR research 2022;2022:2212996
Ursolic Acid Derivative UA232 Promotes Tumor Cell Apoptosis by Inducing Endoplasmic Reticulum Stress and Lysosomal Dysfunction.
Gou W, Luo N, Yu B, Wu H, Wu S, Tian C, Guo J, Ning H, Bi C, Wei H, Hou W, Li Y
International journal of biological sciences 2022;18(6):2639-2651
International journal of biological sciences 2022;18(6):2639-2651
A Novel ER Stress Mediator TMTC3 Promotes Squamous Cell Carcinoma Progression by Activating GRP78/PERK Signaling Pathway.
Yuan H, Zhao Z, Guo Z, Ma L, Han J, Song Y
International journal of biological sciences 2022;18(13):4853-4868
International journal of biological sciences 2022;18(13):4853-4868
Didymin Ameliorates Liver Fibrosis by Alleviating Endoplasmic Reticulum Stress and Glycerophospholipid Metabolism: Based on Transcriptomics and Metabolomics.
Li Y, Li C, Xiong Y, Fang B, Lin X, Huang Q
Drug design, development and therapy 2022;16:1713-1729
Drug design, development and therapy 2022;16:1713-1729
Pitavastatin protects against neomycin-induced ototoxicity through inhibition of endoplasmic reticulum stress.
Wu Y, Meng W, Guan M, Zhao X, Zhang C, Fang Q, Zhang Y, Sun Z, Cai M, Huang D, Yang X, Yu Y, Cui Y, He S, Chai R
Frontiers in molecular neuroscience 2022;15:963083
Frontiers in molecular neuroscience 2022;15:963083
Cryptotanshinone alleviates myocardial ischemia and reperfusion injury in rats to mitigate ER stress-dependent apoptosis by modulating the JAK1/STAT3 axis.
Wang S, Sun L, Zhu Z, Liu J, Ge W, Li B, Wang B
American journal of translational research 2022;14(7):5024-5039
American journal of translational research 2022;14(7):5024-5039
TM9SF4 Is a Crucial Regulator of Inflammation and ER Stress in Inflammatory Bowel Disease.
Xie M, Mak JWY, Yu H, Cheng CTY, Chan HCH, Chan TT, Lau LHS, Wong MTL, Ko WH, Jiang L, Yao X
Cellular and molecular gastroenterology and hepatology 2022;14(2):245-270
Cellular and molecular gastroenterology and hepatology 2022;14(2):245-270
PERK Regulates the Sensitivity of Hepatocellular Carcinoma Cells to High-LET Carbon Ions via either Apoptosis or Ferroptosis.
Zheng X, Liu B, Liu X, Li P, Zhang P, Ye F, Zhao T, Kuang Y, Chen W, Jin X, Li Q
Journal of Cancer 2022;13(2):669-680
Journal of Cancer 2022;13(2):669-680
Endoplasmic reticulum stress promoted acinar cell necroptosis in acute pancreatitis through cathepsinB-mediated AP-1 activation.
Han X, Li B, Bao J, Wu Z, Chen C, Ni J, Shen J, Song P, Peng Q, Wan R, Wang X, Wu J, Hu G
Frontiers in immunology 2022;13:968639
Frontiers in immunology 2022;13:968639
Melatonin promotes sirtuin 1 expression and inhibits IRE1α-XBP1S-CHOP to reduce endoplasmic reticulum stress-mediated apoptosis in chondrocytes.
Qin K, Tang H, Ren Y, Yang D, Li Y, Huang W, Wu Y, Yin Z
Frontiers in pharmacology 2022;13:940629
Frontiers in pharmacology 2022;13:940629
EspF of Enterohemorrhagic Escherichia coli Enhances Apoptosis via Endoplasmic Reticulum Stress in Intestinal Epithelial Cells: An Isobaric Tags for Relative and Absolute Quantitation-Based Comparative Proteomic Analysis.
Wang X, Yan K, Fu M, Liang S, Zhao H, Fu C, Yang L, Song Z, Sun D, Wan C
Frontiers in microbiology 2022;13:900919
Frontiers in microbiology 2022;13:900919
Cold Exposure Induces Intestinal Barrier Damage and Endoplasmic Reticulum Stress in the Colon via the SIRT1/Nrf2 Signaling Pathway.
Guo J, Hu H, Chen Z, Xu J, Nie J, Lu J, Ma L, Ji H, Yuan J, Xu B
Frontiers in physiology 2022;13:822348
Frontiers in physiology 2022;13:822348
C9orf72 regulates the unfolded protein response and stress granule formation by interacting with eIF2α.
Zheng W, Wang K, Wu Y, Yan G, Zhang C, Li Z, Wang L, Chen S
Theranostics 2022;12(17):7289-7306
Theranostics 2022;12(17):7289-7306
Protection of catalpol against triptolide-induced hepatotoxicity by inhibiting excessive autophagy via the PERK-ATF4-CHOP pathway.
Zhang L, Li C, Fu L, Yu Z, Xu G, Zhou J, Shen M, Feng Z, Zhu H, Xie T, Zhou L, Zhou X
PeerJ 2022;10:e12759
PeerJ 2022;10:e12759
COG4 mutation in Saul-Wilson syndrome selectively affects secretion of proteins involved in chondrogenesis in chondrocyte-like cells.
Xia ZJ, Mahajan S, Paul Daniel EJ, Ng BG, Saraswat M, Campos AR, Murad R, He M, Freeze HH
Frontiers in cell and developmental biology 2022;10:979096
Frontiers in cell and developmental biology 2022;10:979096
Adenosine Kinase Inhibition Prevents Severe Acute Pancreatitis via Suppressing Inflammation and Acinar Cell Necroptosis.
Sun S, Han Y, Zhang C, Liu H, Wang B, Cao S, Yuan Q, Wei S, Chen Y
Frontiers in cell and developmental biology 2022;10:827714
Frontiers in cell and developmental biology 2022;10:827714
Endoplasmic Reticulum Stress Is Involved in Muscular Pathogenesis in Idiopathic Inflammatory Myopathies.
Ma X, Gao HJ, Zhang Q, Yang MG, Bi ZJ, Ji SQ, Li Y, Xu L, Bu BT
Frontiers in cell and developmental biology 2022;10:791986
Frontiers in cell and developmental biology 2022;10:791986
HSPA5 repressed ferroptosis to promote colorectal cancer development by maintaining GPX4 stability.
Wang R, Hua L, Ma P, Song Y, Min J, Guo Y, Yang C, Li J, Su H
Neoplasma 2022 Sep;69(5):1054-1069
Neoplasma 2022 Sep;69(5):1054-1069
Substitution of SERCA2 Cys(674) accelerates aortic aneurysm by inducing endoplasmic reticulum stress and promoting cell apoptosis.
Wang L, Yang Z, Wang S, Que Y, Shu X, Wu F, Liu G, Li S, Hu P, Chen H, Shi J, Tong X
British journal of pharmacology 2022 Sep;179(17):4423-4439
British journal of pharmacology 2022 Sep;179(17):4423-4439
Zearalenone Promotes LPS-Induced Oxidative Stress, Endoplasmic Reticulum Stress, and Accelerates Bovine Mammary Epithelial Cell Apoptosis.
Fu Y, Jin Y, Tian Y, Yu H, Wang R, Qi H, Feng B, Zhang J
International journal of molecular sciences 2022 Sep 18;23(18)
International journal of molecular sciences 2022 Sep 18;23(18)
LncRNA-SUSAJ1 Activates the ER Stress Pathway Inhibiting JEV Proliferation by Promoting PK15 Cells Apoptosis.
Yuan Q, Fan J, Wang H, Li X, Yang S, Zhao A, Zhou X
Frontiers in bioscience (Landmark edition) 2022 Sep 13;27(9):260
Frontiers in bioscience (Landmark edition) 2022 Sep 13;27(9):260
Elaiophylin triggers paraptosis and preferentially kills ovarian cancer drug-resistant cells by inducing MAPK hyperactivation.
Li GN, Zhao XJ, Wang Z, Luo MS, Shi SN, Yan DM, Li HY, Liu JH, Yang Y, Tan JH, Zhang ZY, Chen RQ, Lai HL, Huang XY, Zhou JF, Ma D, Fang Y, Gao QL
Signal transduction and targeted therapy 2022 Sep 12;7(1):317
Signal transduction and targeted therapy 2022 Sep 12;7(1):317
Bortezomib prodrug catalytic nanoreactor for chemo/chemodynamic therapy and macrophage re-education.
Huang Y, Guan Z, Ren L, Luo Y, Chen M, Sun Y, He Y, Zeng Z, Dai X, Jiang J, Huang Z, Zhao C
Journal of controlled release : official journal of the Controlled Release Society 2022 Oct;350:332-349
Journal of controlled release : official journal of the Controlled Release Society 2022 Oct;350:332-349
Cold exposure-induced endoplasmic reticulum stress regulates autophagy through the SIRT2/FoxO1 signaling pathway.
Guo J, Nie J, Chen Z, Wang X, Hu H, Xu J, Lu J, Ma L, Ji H, Yuan J, Xu B
Journal of cellular physiology 2022 Oct;237(10):3960-3970
Journal of cellular physiology 2022 Oct;237(10):3960-3970
Substitution of the SERCA2 Cys(674) reactive thiol accelerates atherosclerosis by inducing endoplasmic reticulum stress and inflammation.
Su H, Mei Y, Luo S, Wu H, He Y, Shiraishi Y, Hu P, Cohen RA, Tong X
British journal of pharmacology 2022 Oct;179(20):4778-4791
British journal of pharmacology 2022 Oct;179(20):4778-4791
Severe congenital myasthenic syndromes caused by agrin mutations affecting secretion by motoneurons.
Jacquier A, Risson V, Simonet T, Roussange F, Lacoste N, Ribault S, Carras J, Theuriet J, Girard E, Grosjean I, Le Goff L, Kröger S, Meltoranta J, Bauché S, Sternberg D, Fournier E, Kostera-Pruszczyk A, O'Connor E, Eymard B, Lochmüller H, Martinat C, Schaeffer L
Acta neuropathologica 2022 Oct;144(4):707-731
Acta neuropathologica 2022 Oct;144(4):707-731
Sodium butyrate reduces overnutrition-induced microglial activation and hypothalamic inflammation.
Wang X, Duan C, Li Y, Lu H, Guo K, Ge X, Chen T, Shang Y, Liu H, Zhang D
International immunopharmacology 2022 Oct;111:109083
International immunopharmacology 2022 Oct;111:109083
Targeting A-kinase anchoring protein 12 phosphorylation in hepatic stellate cells regulates liver injury and fibrosis in mouse models.
Ramani K, Mavila N, Abeynayake A, Tomasi ML, Wang J, Matsuda M, Seki E
eLife 2022 Oct 4;11
eLife 2022 Oct 4;11
SYNJ2BP Improves the Production of Lentiviral Envelope Protein by Facilitating the Formation of Mitochondrion-Associated Endoplasmic Reticulum Membrane.
Duan Y, Wang X, Sun K, Lin Y, Wang X, Chen K, Yang G, Wang X, Du C
Journal of virology 2022 Oct 26;96(20):e0054922
Journal of virology 2022 Oct 26;96(20):e0054922
Exploring the molecular mechanisms underlie the endoplasmic reticulum stress-mediated methylmercury-induced neuronal developmental damage.
Pan J, Li X, Liu H, Wang C, Xu S, Xu B, Deng Y, Yang T, Liu W
Ecotoxicology and environmental safety 2022 Oct 15;245:114099
Ecotoxicology and environmental safety 2022 Oct 15;245:114099
Melatonin alleviates PM(2.5) -induced glucose metabolism disorder and lipidome alteration by regulating endoplasmic reticulum stress.
Du Z, Hu J, Lin L, Liang Q, Sun M, Sun Z, Duan J
Journal of pineal research 2022 Nov;73(4):e12823
Journal of pineal research 2022 Nov;73(4):e12823
Galectin‑1 binds GRP78 to promote the proliferation and metastasis of gastric cancer.
Zhang Q, Ali M, Wang Y, Sun QN, Zhu XD, Tang D, Wang W, Zhang CY, Zhou HH, Wang DR
International journal of oncology 2022 Nov;61(5)
International journal of oncology 2022 Nov;61(5)
Vitamin C modulates the levels of several proteins of the mitochondrial complex III and its activity in the mouse liver.
Aumailley L, Bourassa S, Gotti C, Droit A, Lebel M
Redox biology 2022 Nov;57:102491
Redox biology 2022 Nov;57:102491
OL-FS13 alleviates experimental cerebral ischemia-reperfusion injury.
Liu N, Li Y, Yang Y, Shu L, Liu Y, Wu Y, Sun D, Kang Z, Zhang Y, Ni D, Wei Z, Li S, Yang M, Wang Y, Sun J, Yang X
Experimental neurology 2022 Nov;357:114180
Experimental neurology 2022 Nov;357:114180
Pterostilbene attenuates intrauterine growth retardation-induced colon inflammation in piglets by modulating endoplasmic reticulum stress and autophagy.
Chen Y, Zhang H, Li Y, Ji S, Jia P, Wang T
Journal of animal science and biotechnology 2022 Nov 4;13(1):125
Journal of animal science and biotechnology 2022 Nov 4;13(1):125
CircZXDC Promotes Vascular Smooth Muscle Cell Transdifferentiation via Regulating miRNA-125a-3p/ABCC6 in Moyamoya Disease.
Liu Y, Huang Y, Zhang X, Ma X, He X, Gan C, Zou X, Wang S, Shu K, Lei T, Zhang H
Cells 2022 Nov 26;11(23)
Cells 2022 Nov 26;11(23)
Aging Impairs Adaptive Unfolded Protein Response and Drives Beta Cell Dedifferentiation in Humans.
Song J, Ni Q, Sun J, Xie J, Liu J, Ning G, Wang W, Wang Q
The Journal of clinical endocrinology and metabolism 2022 Nov 25;107(12):3231-3241
The Journal of clinical endocrinology and metabolism 2022 Nov 25;107(12):3231-3241
Hydrogen Sulfide Regulates SERCA2a Ubiquitylation via Muscle RING Finger-1 S-Sulfhydration to Affect Cardiac Contractility in db/db Mice.
Peng S, Zhao D, Li Q, Wang M, Zhang S, Pang K, Huang J, Lu F, Chen H, Zhang W
Cells 2022 Nov 2;11(21)
Cells 2022 Nov 2;11(21)
Autophagy Mediates Escherichia Coli-Induced Cellular Inflammatory Injury by Regulating Calcium Mobilization, Mitochondrial Dysfunction, and Endoplasmic Reticulum Stress.
Liu J, Qiu R, Liu R, Song P, Lin P, Chen H, Zhou D, Wang A, Jin Y
International journal of molecular sciences 2022 Nov 16;23(22)
International journal of molecular sciences 2022 Nov 16;23(22)
Inhibition of human peptide deformylase by actinonin sensitizes glioblastoma cells to temozolomide chemotherapy.
Lan B, Zhao H, He Y, Zhao Z, Wang N, Gao Y
Experimental cell research 2022 Nov 15;420(2):113358
Experimental cell research 2022 Nov 15;420(2):113358
Zinc Alleviates Arsenic-Induced Inflammation and Apoptosis in the Head Kidney of Common Carp by Inhibiting Oxidative Stress and Endoplasmic Reticulum Stress.
Xing P, Zhang Y, Chi Q, Li S
Biological trace element research 2022 May;200(5):2380-2390
Biological trace element research 2022 May;200(5):2380-2390
Manganese Mitigates Heat Stress-Induced Apoptosis by Alleviating Endoplasmic Reticulum Stress and Activating the NRF2/SOD2 Pathway in Primary Chick Embryonic Myocardial Cells.
Qin S, Wang R, Tang D, Qin S, Guo Y, Shi Z
Biological trace element research 2022 May;200(5):2312-2320
Biological trace element research 2022 May;200(5):2312-2320
Dihydroartemisinin alleviates steatosis and inflammation in nonalcoholic steatohepatitis by decreasing endoplasmic reticulum stress and oxidative stress.
Li T, Chen Y, Tan P, Shi H, Huang Z, Cai T, Cheng Y, Du Y, Fu W
Bioorganic chemistry 2022 May;122:105737
Bioorganic chemistry 2022 May;122:105737
Azithromycin alleviates the severity of rheumatoid arthritis by targeting the unfolded protein response component of glucose-regulated protein 78 (GRP78).
Zhang Y, Ge L, Song G, Zhang R, Li S, Shi H, Zhang H, Li Y, Pan J, Wang L, Han J
British journal of pharmacology 2022 Mar;179(6):1201-1219
British journal of pharmacology 2022 Mar;179(6):1201-1219
Fucoidan protects the pancreas and improves glucose metabolism through inhibiting inflammation and endoplasmic reticulum stress in T2DM rats.
Liu Y, Huang H, Xu Z, Xue Y, Zhang D, Zhang Y, Li W, Li X
Food & function 2022 Mar 7;13(5):2693-2709
Food & function 2022 Mar 7;13(5):2693-2709
Endoplasmic reticulum chaperone genes encode effectors of long-term memory.
Chatterjee S, Bahl E, Mukherjee U, Walsh EN, Shetty MS, Yan AL, Vanrobaeys Y, Lederman JD, Giese KP, Michaelson J, Abel T
Science advances 2022 Mar 25;8(12):eabm6063
Science advances 2022 Mar 25;8(12):eabm6063
Estrogen inhibits endoplasmic reticulum stress and ameliorates myocardial ischemia/reperfusion injury in rats by upregulating SERCA2a.
Chen J, Liu Y, Pan D, Xu T, Luo Y, Wu W, Wu P, Zhu H, Li D
Cell communication and signaling : CCS 2022 Mar 24;20(1):38
Cell communication and signaling : CCS 2022 Mar 24;20(1):38
Pathogenic Role of Endoplasmic Reticulum Stress in Diabetic Corneal Endothelial Dysfunction.
Chen C, Zhang B, Xue J, Li Z, Dou S, Chen H, Wang Q, Qu M, Wang H, Zhang Y, Wan L, Zhou Q, Xie L
Investigative ophthalmology & visual science 2022 Mar 2;63(3):4
Investigative ophthalmology & visual science 2022 Mar 2;63(3):4
Gestational exposure to BDE-209 induces placental injury via the endoplasmic reticulum stress-mediated PERK/ATF4/CHOP signaling pathway.
Zhao Y, Fan K, Zhu Y, Zhao Y, Cai J, Jin L
Ecotoxicology and environmental safety 2022 Mar 15;233:113307
Ecotoxicology and environmental safety 2022 Mar 15;233:113307
Protective Effects of Taraxasterol against Deoxynivalenol-Induced Damage to Bovine Mammary Epithelial Cells.
Wang J, Zheng K, Jin Y, Fu Y, Wang R, Zhang J
Toxins 2022 Mar 15;14(3)
Toxins 2022 Mar 15;14(3)
A rapid and simple procedure for the isolation and cultivation of fibroblast-like cells from medaka and zebrafish embryos and fin clip biopsies.
Beedgen L, Hüllen A, Gücüm S, Thumberger T, Wittbrodt J, Thiel C
Laboratory animals 2022 Jun;56(3):270-278
Laboratory animals 2022 Jun;56(3):270-278
Contribution of Endoplasmic Reticulum Stress to the Clinical Instability of Carotid Plaques in Human Carotid Stenosis.
Hosoda K, Imahori T, Tanaka K, Uno T, Nakai T, Kohta M, Fujita A, Sasayama T
Translational stroke research 2022 Jun;13(3):420-431
Translational stroke research 2022 Jun;13(3):420-431
Recombinant ACE2 protein protects against acute lung injury induced by SARS-CoV-2 spike RBD protein.
Zhang L, Zhang Y, Qin X, Jiang X, Zhang J, Mao L, Jiang Z, Jiang Y, Liu G, Qiu J, Chen C, Qiu F, Zou Z
Critical care (London, England) 2022 Jun 9;26(1):171
Critical care (London, England) 2022 Jun 9;26(1):171
ATF6 prevents DNA damage and cell death in colon cancer cells undergoing ER stress.
Benedetti R, Romeo MA, Arena A, Gilardini Montani MS, Di Renzo L, D'Orazi G, Cirone M
Cell death discovery 2022 Jun 25;8(1):295
Cell death discovery 2022 Jun 25;8(1):295
Intravenously transplanted mesenchymal stromal cells: a new endocrine reservoir for cardioprotection.
Huang A, Liu Y, Qi X, Chen S, Huang H, Zhang J, Han Z, Han ZC, Li Z
Stem cell research & therapy 2022 Jun 17;13(1):253
Stem cell research & therapy 2022 Jun 17;13(1):253
Exposure of mouse oocytes to N,N-dimethylformamide impairs mitochondrial functions and reduces oocyte quality.
Fei CF, Guo SM, Yin Y, He X, Zhou LQ
Environmental toxicology 2022 Jul;37(7):1563-1574
Environmental toxicology 2022 Jul;37(7):1563-1574
The cardiotoxicity of asthmatic rats after traffic-related PM(2.5) and water-soluble components exposure mediated by endoplasmic reticulum stress and autophagy.
Tian J, Shi H, Wang X, Wu H, Wang C, Liu N, Wang D, Shi D, Zhang H, Zhang Z
Environmental science and pollution research international 2022 Jul;29(33):50704-50716
Environmental science and pollution research international 2022 Jul;29(33):50704-50716
Peste des petits ruminants virus induces ERS-mediated autophagy to promote virus replication.
Wen B, Yang L, Guo J, Chang W, Wei S, Yu S, Qi X, Xue Q, Wang J
Veterinary microbiology 2022 Jul;270:109451
Veterinary microbiology 2022 Jul;270:109451
ER stress-related protein, CHOP, may serve as a biomarker of mechanical asphyxia: a primary study.
Hu Y, Tian L, Ma K, Han L, Li W, Hu L, Fei G, Zhang T, Yu D, Xu L, Wang F, Xiao B, Chen L
International journal of legal medicine 2022 Jul;136(4):1091-1104
International journal of legal medicine 2022 Jul;136(4):1091-1104
Glyphosate exposure deteriorates oocyte meiotic maturation via induction of organelle dysfunctions in pigs.
Xing C, Chen S, Wang Y, Pan Z, Zou Y, Sun S, Ren Z, Zhang Y
Journal of animal science and biotechnology 2022 Jul 8;13(1):80
Journal of animal science and biotechnology 2022 Jul 8;13(1):80
The Role of Ferroptosis in the Damage of Human Proximal Tubule Epithelial Cells Caused by Perfluorooctane Sulfonate.
Wang P, Liu D, Yan S, Liang Y, Cui J, Guo L, Ren S, Chen P
Toxics 2022 Jul 29;10(8)
Toxics 2022 Jul 29;10(8)
COVID-19 lung disease shares driver AT2 cytopathic features with Idiopathic pulmonary fibrosis.
Sinha S, Castillo V, Espinoza CR, Tindle C, Fonseca AG, Dan JM, Katkar GD, Das S, Sahoo D, Ghosh P
bioRxiv : the preprint server for biology 2022 Jul 18;
bioRxiv : the preprint server for biology 2022 Jul 18;
Monitoring Protein Import into the Endoplasmic Reticulum in Living Cells with Proximity Labeling.
Lyu Z, Sycks MM, Espinoza MF, Nguyen KK, Montoya MR, Galapate CM, Mei L, Genereux JC
ACS chemical biology 2022 Jul 15;17(7):1963-1977
ACS chemical biology 2022 Jul 15;17(7):1963-1977
TSG-6 released from adipose stem cells-derived small extracellular vesicle protects against spinal cord ischemia reperfusion injury by inhibiting endoplasmic reticulum stress.
Lu X, Lv C, Zhao Y, Wang Y, Li Y, Ji C, Wang Z, Ye W, Yu S, Bai J, Cai W
Stem cell research & therapy 2022 Jul 13;13(1):291
Stem cell research & therapy 2022 Jul 13;13(1):291
The impairment of DDR reduces XBP1s, further increasing DNA damage, and triggers autophagy via PERK/eIF2alpha in MM and IRE1alpha/JNK1/2 in PEL cells.
Arena A, Romeo MA, Benedetti R, Gilardini Montani MS, Cirone M
Biochemical and biophysical research communications 2022 Jul 12;613:19-25
Biochemical and biophysical research communications 2022 Jul 12;613:19-25
TRPV4 contributes to ER stress and inflammation: implications for Parkinson's disease.
Liu N, Bai L, Lu Z, Gu R, Zhao D, Yan F, Bai J
Journal of neuroinflammation 2022 Jan 29;19(1):26
Journal of neuroinflammation 2022 Jan 29;19(1):26
Down-regulating GRP78 reverses pirarubicin resistance of triple negative breast cancer by miR-495-3p mimics and involves the p-AKT/mTOR pathway.
Liu M, Yang J, Lv W, Wang S, Du T, Zhang K, Wu Y, Feng X
Bioscience reports 2022 Jan 28;42(1)
Bioscience reports 2022 Jan 28;42(1)
Nrf2 loss of function exacerbates endoplasmic reticulum stress-induced apoptosis in TBI mice.
Sun G, Zhao Z, Lang J, Sun B, Zhao Q
Neuroscience letters 2022 Jan 23;770:136400
Neuroscience letters 2022 Jan 23;770:136400
Zinc Supplementation Enhances the Pro-Death Function of UPR in Lymphoma Cells Exposed to Radiation.
Gonnella R, Guttieri L, Gilardini Montani MS, Santarelli R, Bassetti E, D'Orazi G, Cirone M
Biology 2022 Jan 13;11(1)
Biology 2022 Jan 13;11(1)
The PERK/PKR-eIF2α Pathway Negatively Regulates Porcine Hemagglutinating Encephalomyelitis Virus Replication by Attenuating Global Protein Translation and Facilitating Stress Granule Formation.
Shi J, Li Z, Xu R, Zhang J, Zhou Q, Gao R, Lu H, Lan Y, Zhao K, He H, Gao F, He W
Journal of virology 2022 Jan 12;96(1):e0169521
Journal of virology 2022 Jan 12;96(1):e0169521
Glucose consumption of vascular cell types in culture: toward optimization of experimental conditions.
Torimoto K, Okuno K, Kuroda R, Shanas N, Cicalese SM, Eguchi K, Elliott KJ, Kawai T, Corbett CB, Peluzzo AM, St Paul AK, Autieri MV, Scalia R, Rizzo V, Hashimoto T, Eguchi S
American journal of physiology. Cell physiology 2022 Jan 1;322(1):C73-C85
American journal of physiology. Cell physiology 2022 Jan 1;322(1):C73-C85
Inhibition of the miR-193b-3p protects against oxidized low-density lipoprotein-induced HUVECs injury by upregulating ALDH2.
Bai Y, Wang M, Yang Y, Liu X, Chen Q, Guo Z
Cell biology international 2022 Feb;46(2):192-202
Cell biology international 2022 Feb;46(2):192-202
Sigma-1 receptor activity in primary sensory neurons is a critical driver of neuropathic pain.
Shin SM, Wang F, Qiu C, Itson-Zoske B, Hogan QH, Yu H
Gene therapy 2022 Feb;29(1-2):1-15
Gene therapy 2022 Feb;29(1-2):1-15
Therapeutic effect and mechanism of 4-phenyl butyric acid on renal ischemia-reperfusion injury in mice.
Wang X, Zhang Y, Wuyun K, Gong H
Experimental and therapeutic medicine 2022 Feb;23(2):144
Experimental and therapeutic medicine 2022 Feb;23(2):144
Zinc Protects against Heat Stress-Induced Apoptosis via the Inhibition of Endoplasmic Reticulum Stress in TM3 Leydig Cells.
Xiong Y, Li J, He S
Biological trace element research 2022 Feb;200(2):728-739
Biological trace element research 2022 Feb;200(2):728-739
ATF6-Mediated Unfolded Protein Response Facilitates Adeno-associated Virus 2 (AAV2) Transduction by Releasing the Suppression of the AAV Receptor on Endoplasmic Reticulum Stress.
Cui M, Zhao Q, Wang J, Si Y, Cheng S, Ding W
Journal of virology 2022 Feb 9;96(3):e0110321
Journal of virology 2022 Feb 9;96(3):e0110321
Changes of flavin-containing monooxygenases and trimethylamine-N-oxide may be involved in the promotion of non-alcoholic fatty liver disease by intestinal microbiota metabolite trimethylamine.
Shi C, Pei M, Wang Y, Chen Q, Cao P, Zhang L, Guo J, Deng W, Wang L, Li X, Gong Z
Biochemical and biophysical research communications 2022 Feb 26;594:1-7
Biochemical and biophysical research communications 2022 Feb 26;594:1-7
Perfluorooctanoic acid induces hepatocellular endoplasmic reticulum stress and mitochondrial-mediated apoptosis in vitro via endoplasmic reticulum-mitochondria communication.
Wang Q, Chen W, Zhang B, Gao Z, Zhang Q, Deng H, Han L, Shen XL
Chemico-biological interactions 2022 Feb 25;354:109844
Chemico-biological interactions 2022 Feb 25;354:109844
A missing piece of the puzzle in pulmonary fibrosis: anoikis resistance promotes fibroblast activation.
Yin J, Wang J, Zhang X, Liao Y, Luo W, Wang S, Ding J, Huang J, Chen M, Wang W, Fang S, Chao J
Cell & bioscience 2022 Feb 25;12(1):21
Cell & bioscience 2022 Feb 25;12(1):21
Transketolase promotes colorectal cancer metastasis through regulating AKT phosphorylation.
Li M, Zhao X, Yong H, Xu J, Qu P, Qiao S, Hou P, Li Z, Chu S, Zheng J, Bai J
Cell death & disease 2022 Feb 2;13(2):99
Cell death & disease 2022 Feb 2;13(2):99
African Swine Fever Virus K205R Induces ER Stress and Consequently Activates Autophagy and the NF-κB Signaling Pathway.
Wang Q, Zhou L, Wang J, Su D, Li D, Du Y, Yang G, Zhang G, Chu B
Viruses 2022 Feb 15;14(2)
Viruses 2022 Feb 15;14(2)
Endoplasmic reticulum stress mediates parathyroid hormone-induced apoptosis in vascular smooth muscle cells.
Duan S, Chen X, Liu Y, Guo W, Liu W
Renal failure 2022 Dec;44(1):126-136
Renal failure 2022 Dec;44(1):126-136
The Mechano-Ubiquitinome of Articular Cartilage: Differential Ubiquitination and Activation of a Group of ER-Associated DUBs and ER Stress Regulators.
Kaokhum N, Pinto-Fernández A, Wilkinson M, Kessler BM, Ismail HM
Molecular & cellular proteomics : MCP 2022 Dec;21(12):100419
Molecular & cellular proteomics : MCP 2022 Dec;21(12):100419
Exosome modification to better alleviates endoplasmic reticulum stress induced chondrocyte apoptosis and osteoarthritis.
Wang Y, Fan A, Lu L, Pan Z, Ma M, Luo S, Liu Z, Yang L, Cai J, Yin F
Biochemical pharmacology 2022 Dec;206:115343
Biochemical pharmacology 2022 Dec;206:115343
PRDX6 inhibits hepatic stellate cells activation and fibrosis via promoting MANF secretion.
Tao X, Wang D, Liang Y, Yang L, He E, Zhou J, He Y, Liang J, Wang P, Chhetri G, Li Q, Shen Y, Shen Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Dec;156:113931
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Dec;156:113931
Corynoxine suppresses pancreatic cancer growth primarily via ROS-p38 mediated cytostatic effects.
Wen C, Ruan Q, Li Z, Zhou X, Yang X, Xu P, Akuetteh PDP, Xu Z, Deng J
British journal of cancer 2022 Dec;127(12):2108-2117
British journal of cancer 2022 Dec;127(12):2108-2117
Gut dysbacteriosis attenuates resistance to Mycobacterium bovis infection by decreasing cyclooxygenase 2 to inhibit endoplasmic reticulum stress.
Wang H, Yao J, Chen Y, Wang Y, Liu Y, Liao Y, Liang Z, Dong YH, Qu M, Ge X, Zhou X
Emerging microbes & infections 2022 Dec;11(1):1806-1818
Emerging microbes & infections 2022 Dec;11(1):1806-1818
Endoplasmic Reticulum Chemical Chaperone 3-Hydroxy-2-Naphthoic Acid Reduces Angiotensin II-Induced Vascular Remodeling and Hypertension In Vivo and Protein Synthesis In Vitro.
Cicalese S, Torimoto K, Okuno K, Elliott KJ, Rizzo V, Hashimoto T, Eguchi S
Journal of the American Heart Association 2022 Dec 6;11(23):e028201
Journal of the American Heart Association 2022 Dec 6;11(23):e028201
Deficiency of CFB attenuates renal tubulointerstitial damage by inhibiting ceramide synthesis in diabetic kidney disease.
Sun ZJ, Chang DY, Chen M, Zhao MH
JCI insight 2022 Dec 22;7(24)
JCI insight 2022 Dec 22;7(24)
Endosomal lipid signaling reshapes the endoplasmic reticulum to control mitochondrial function.
Jang W, Puchkov D, Samsó P, Liang Y, Nadler-Holly M, Sigrist SJ, Kintscher U, Liu F, Mamchaoui K, Mouly V, Haucke V
Science (New York, N.Y.) 2022 Dec 16;378(6625):eabq5209
Science (New York, N.Y.) 2022 Dec 16;378(6625):eabq5209
Enhanced tumor targeting and timely viral release of mesenchymal stem cells/oncolytic virus complex due to GRP78 and inducible E1B55K expressions greatly increase the antitumor effect of systemic treatment.
Choi S, Hong JA, Choi HJ, Song JJ
Molecular therapy oncolytics 2022 Dec 15;27:26-47
Molecular therapy oncolytics 2022 Dec 15;27:26-47
Translational control by maternal Nanog promotes oogenesis and early embryonic development.
He M, Jiao S, Zhang R, Ye D, Wang H, Sun Y
Development (Cambridge, England) 2022 Dec 15;149(24)
Development (Cambridge, England) 2022 Dec 15;149(24)
COVID-19 lung disease shares driver AT2 cytopathic features with Idiopathic pulmonary fibrosis.
Sinha S, Castillo V, Espinoza CR, Tindle C, Fonseca AG, Dan JM, Katkar GD, Das S, Sahoo D, Ghosh P
EBioMedicine 2022 Aug;82:104185
EBioMedicine 2022 Aug;82:104185
Sodium selenite attenuates zearalenone-induced apoptosis through inhibition of endoplasmic reticulum stress in goat trophoblast cells.
Xiong Y, Li B, Li J, Jin E, He S
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 2022 Aug;35(4):699-710
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 2022 Aug;35(4):699-710
A novel 8-hydroxyquinoline derivative induces breast cancer cell death through paraptosis and apoptosis.
Ma L, Xuan X, Fan M, Zhang Y, Yuan G, Huang G, Liu Z
Apoptosis : an international journal on programmed cell death 2022 Aug;27(7-8):577-589
Apoptosis : an international journal on programmed cell death 2022 Aug;27(7-8):577-589
Inhibition of USP14 influences alphaherpesvirus proliferation by degrading viral VP16 protein via ER stress-triggered selective autophagy.
Ming SL, Zhang S, Wang Q, Zeng L, Zhou LY, Wang MD, Ma YX, Han LQ, Zhong K, Zhu HS, Bai YL, Yang GY, Wang J, Chu BB
Autophagy 2022 Aug;18(8):1801-1821
Autophagy 2022 Aug;18(8):1801-1821
Non-Esterified Fatty Acid Induces ER Stress-Mediated Apoptosis via ROS/MAPK Signaling Pathway in Bovine Mammary Epithelial Cells.
Yan Y, Huang J, Huan C, Li L, Li C
Metabolites 2022 Aug 27;12(9)
Metabolites 2022 Aug 27;12(9)
Interleukin-33 regulates the endoplasmic reticulum stress of human myometrium via an influx of calcium during initiation of labor.
Chen L, Song Z, Cao X, Fan M, Zhou Y, Zhang G
eLife 2022 Aug 23;11
eLife 2022 Aug 23;11
Lysyl hydroxylase 2 mediated collagen post-translational modifications and functional outcomes.
Terajima M, Taga Y, Nakamura T, Guo HF, Kayashima Y, Maeda-Smithies N, Parag-Sharma K, Kim JS, Amelio AL, Mizuno K, Kurie JM, Yamauchi M
Scientific reports 2022 Aug 22;12(1):14256
Scientific reports 2022 Aug 22;12(1):14256
Si-Wu Water Extracts Protect against Colonic Mucus Barrier Damage by Regulating Muc2 Mucin Expression in Mice Fed a High-Fat Diet.
Ruan Z, Yu Y, Han P, Zhang L, Hu Z
Foods (Basel, Switzerland) 2022 Aug 18;11(16)
Foods (Basel, Switzerland) 2022 Aug 18;11(16)
Concomitant Inhibition of IRE1α/XBP1 Axis of UPR and PARP: A Promising Therapeutic Approach against c-Myc and Gammaherpesvirus-Driven B-Cell Lymphomas.
Benedetti R, Arena A, Romeo MA, Gilardini Montani MS, Gonnella R, Santarelli R, Trivedi P, Cirone M
International journal of molecular sciences 2022 Aug 14;23(16)
International journal of molecular sciences 2022 Aug 14;23(16)
TIMP2 mediates endoplasmic reticulum stress contributing to sepsis-induced acute kidney injury.
Jiang N, Huang R, Zhang J, Xu D, Li T, Sun Z, Su L, Peng Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Apr;36(4):e22228
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Apr;36(4):e22228
Endoplasmic reticulum stress affects mouse salivary protein secretion induced by chronic administration of an α(1)-adrenergic agonist.
Yoshino Y, Imamura T, Yamachika S, Ohshima T, Ushikoshi-Nakayama R, Inoue H, Saito I, Nakagawa Y
Histochemistry and cell biology 2022 Apr;157(4):443-457
Histochemistry and cell biology 2022 Apr;157(4):443-457
ZBM-H-induced activation of GRP78 ATPase promotes apoptosis via annexin A7 in A549 lung cancer cells.
Ning J, Wang X, Li N, Cui X, Li N, Zhao B, Miao J, Lin Z
Journal of cellular biochemistry 2022 Apr;123(4):798-806
Journal of cellular biochemistry 2022 Apr;123(4):798-806
Citrinin-Induced Hepatotoxicity in Mice Is Regulated by the Ca(2+)/Endoplasmic Reticulum Stress Signaling Pathway.
Wu D, Yang C, Yang M, Wu Y, Mao Y, Zhou X, Wang J, Yuan Z, Wu J
Toxins 2022 Apr 6;14(4)
Toxins 2022 Apr 6;14(4)
Dietary Tryptophan Supplementation Improves Antioxidant Status and Alleviates Inflammation, Endoplasmic Reticulum Stress, Apoptosis, and Pyroptosis in the Intestine of Piglets after Lipopolysaccharide Challenge.
Liu G, Tao J, Lu J, Jia G, Zhao H, Chen X, Tian G, Cai J, Zhang R, Wang J
Antioxidants (Basel, Switzerland) 2022 Apr 28;11(5)
Antioxidants (Basel, Switzerland) 2022 Apr 28;11(5)
Exercise activates autophagy and regulates endoplasmic reticulum stress in muscle of high-fat diet mice to alleviate insulin resistance.
Cheng F, Dun Y, Cheng J, Ripley-Gonzalez JW, Jiang W, You B, Liu S
Biochemical and biophysical research communications 2022 Apr 23;601:45-51
Biochemical and biophysical research communications 2022 Apr 23;601:45-51
Chlorogenic acid improves the intestinal barrier by relieving endoplasmic reticulum stress and inhibiting ROCK/MLCK signaling pathways.
Song L, Wu T, Zhang L, Wan J, Ruan Z
Food & function 2022 Apr 20;13(8):4562-4575
Food & function 2022 Apr 20;13(8):4562-4575
Nicotinamide mononucleotide alleviates heat stress-induced oxidative stress and apoptosis in BMECs through reducing mitochondrial damage and endoplasmic reticulum stress.
Zeng HF, Xu J, Wang XL, Li SJ, Han ZY
Ecotoxicology and environmental safety 2022 Apr 15;235:113441
Ecotoxicology and environmental safety 2022 Apr 15;235:113441
Long noncoding RNA SH3PXD2A-AS1 promotes NSCLC proliferation and accelerates cell cycle progression by interacting with DHX9.
Zhou Y, Yong H, Cui W, Chu S, Li M, Li Z, Bai J, Zhang H
Cell death discovery 2022 Apr 11;8(1):192
Cell death discovery 2022 Apr 11;8(1):192
GPX4 degradation via chaperone-mediated autophagy contributes to antimony-triggered neuronal ferroptosis.
Yu S, Li Z, Zhang Q, Wang R, Zhao Z, Ding W, Wang F, Sun C, Tang J, Wang X, Zhang H, Huang R, Wu Q, Jiang J, Zhao X
Ecotoxicology and environmental safety 2022 Apr 1;234:113413
Ecotoxicology and environmental safety 2022 Apr 1;234:113413
Eicosapentaenoic Acid-Induced Autophagy Attenuates Intervertebral Disc Degeneration by Suppressing Endoplasmic Reticulum Stress, Extracellular Matrix Degradation, and Apoptosis.
Lin Z, Ni L, Teng C, Zhang Z, Wu L, Jin Y, Lu X, Lin Z
Frontiers in cell and developmental biology 2021;9:745621
Frontiers in cell and developmental biology 2021;9:745621
Plasma Purification Treatment Relieves the Damage of Hyperlipidemia to PBMCs.
Zhang XM, Gu YH, Deng H, Xu ZQ, Zhong ZY, Lyu XJ, Jin HM, Yang XH
Frontiers in cardiovascular medicine 2021;8:691336
Frontiers in cardiovascular medicine 2021;8:691336
Pharmacological Activating Transcription Factor 6 Activation Is Beneficial for Liver Retrieval With ex vivo Normothermic Mechanical Perfusion From Cardiac Dead Donor Rats.
Cheng N, Shi JH, Jin Y, Shi YB, Liu XD, Zhang HP, Cao SL, Yang H, Guo WZ, Zhang SJ
Frontiers in surgery 2021;8:665260
Frontiers in surgery 2021;8:665260
Curcumin Alleviates Palmitic Acid-Induced LOX-1 Upregulation by Suppressing Endoplasmic Reticulum Stress in HUVECs.
Luo R, Zhao L, Li S, Chen P, Wang L, Yu H, Cai K, Yu Q, Tian W
BioMed research international 2021;2021:9983725
BioMed research international 2021;2021:9983725
Mechanosensitive Ion Channel Piezo1 Activated by Matrix Stiffness Regulates Oxidative Stress-Induced Senescence and Apoptosis in Human Intervertebral Disc Degeneration.
Wang B, Ke W, Wang K, Li G, Ma L, Lu S, Xiang Q, Liao Z, Luo R, Song Y, Hua W, Wu X, Zhang Y, Zeng X, Yang C
Oxidative medicine and cellular longevity 2021;2021:8884922
Oxidative medicine and cellular longevity 2021;2021:8884922
Wenxin Granules Regulate Endoplasmic Reticulum Stress Unfolded Protein Response and Improve Ventricular Remodeling on Rats with Myocardial Infarction.
Liu K, Lv M, Ji X, Lou L, Nie B, Zhao J, Wu A, Zhao M
Evidence-based complementary and alternative medicine : eCAM 2021;2021:7375549
Evidence-based complementary and alternative medicine : eCAM 2021;2021:7375549
Ginkgo Biloba Extract EGB761 Ameliorates the Extracellular Matrix Accumulation and Mesenchymal Transformation of Renal Tubules in Diabetic Kidney Disease by Inhibiting Endoplasmic Reticulum Stress.
Han J, Pang X, Shi X, Zhang Y, Peng Z, Xing Y
BioMed research international 2021;2021:6657206
BioMed research international 2021;2021:6657206
The Dietary Supplement γ-Oryzanol Attenuates Hepatic Ischemia Reperfusion Injury via Inhibiting Endoplasmic Reticulum Stress and HMGB1/NLRP3 Inflammasome.
Du Y, Zhong F, Cheng H, Li T, Chen Y, Tan P, Huang M, Liang T, Liu Y, Xia X, Fu W
Oxidative medicine and cellular longevity 2021;2021:4628050
Oxidative medicine and cellular longevity 2021;2021:4628050
Endophilin A2-mediated alleviation of endoplasmic reticulum stress-induced cardiac injury involves the suppression of ERO1α/IP(3)R signaling pathway.
Liu Y, Hu R, Shen H, Mo Q, Wang X, Zhang G, Li S, Liang G, Hou N, Luo J
International journal of biological sciences 2021;17(13):3672-3688
International journal of biological sciences 2021;17(13):3672-3688
Sini San Inhibits Chronic Psychological Stress-Induced Breast Cancer Stemness by Suppressing Cortisol-Mediated GRP78 Activation.
Zheng Y, Zhang J, Huang W, Zhong LLD, Wang N, Wang S, Yang B, Wang X, Pan B, Situ H, Lin Y, Liu X, Shi Y, Wang Z
Frontiers in pharmacology 2021;12:714163
Frontiers in pharmacology 2021;12:714163
Autophagy Blockade by Ai Du Qing Formula Promotes Chemosensitivity of Breast Cancer Stem Cells Via GRP78/β-Catenin/ABCG2 Axis.
Liao M, Wang C, Yang B, Huang D, Zheng Y, Wang S, Wang X, Zhang J, Tang C, Xu Z, He Y, Huang R, Zhang F, Wang Z, Wang N
Frontiers in pharmacology 2021;12:659297
Frontiers in pharmacology 2021;12:659297
Dl-3-n-Butylphthalide Ameliorates Diabetic Nephropathy by Ameliorating Excessive Fibrosis and Podocyte Apoptosis.
Xu J, Tang Z, He Y, Cai S, Wang B, Zhang S, Wu M, Qian K, Zhang K, Chai B, Chen G, Xu K, Ji H, Xiao J, Wu Y
Frontiers in pharmacology 2021;12:628950
Frontiers in pharmacology 2021;12:628950
Hypothermic oxygenated perfusion with defatting cocktail further improves steatotic liver grafts in a transplantation rat model.
Lin F, Zhen F, Yan X, Shaojun Y, Guizhu P, Yanfeng W, Qifa Y
Artificial organs 2021 Sep;45(9):E304-E316
Artificial organs 2021 Sep;45(9):E304-E316
Exosomal ERp44 derived from ER-stressed cells strengthens cisplatin resistance of nasopharyngeal carcinoma.
Xia T, Tian H, Zhang K, Zhang S, Chen W, Shi S, You Y
BMC cancer 2021 Sep 8;21(1):1003
BMC cancer 2021 Sep 8;21(1):1003
Role of UPR Sensor Activation in Cell Death-Survival Decision of Colon Cancer Cells Stressed by DPE Treatment.
Benedetti R, Gilardini Montani MS, Romeo MA, Arena A, Santarelli R, D'Orazi G, Cirone M
Biomedicines 2021 Sep 18;9(9)
Biomedicines 2021 Sep 18;9(9)
Autophagy protein NRBF2 attenuates endoplasmic reticulum stress-associated neuroinflammation and oxidative stress via promoting autophagosome maturation by interacting with Rab7 after SAH.
Zeng H, Chen H, Li M, Zhuang J, Peng Y, Zhou H, Xu C, Yu Q, Fu X, Cao S, Cai J, Yan F, Chen G
Journal of neuroinflammation 2021 Sep 16;18(1):210
Journal of neuroinflammation 2021 Sep 16;18(1):210
Hydrogen sulphide reduced the accumulation of lipid droplets in cardiac tissues of db/db mice via Hrd1 S-sulfhydration.
Sun Y, Zhang L, Lu B, Wen J, Wang M, Zhang S, Li Q, Shu F, Lu F, Liu N, Peng S, Zhao Y, Dong S, Lu F, Zhang W, Wang Y
Journal of cellular and molecular medicine 2021 Oct;25(19):9154-9167
Journal of cellular and molecular medicine 2021 Oct;25(19):9154-9167
Osthole induces apoptosis of the HT-29 cells via endoplasmic reticulum stress and autophagy.
Zhou XH, Kang J, Zhong ZD, Cheng Y
Oncology letters 2021 Oct;22(4):726
Oncology letters 2021 Oct;22(4):726
GnRHa protects the ovarian reserve by reducing endoplasmic reticulum stress during cyclophosphamide-based chemotherapy.
Li X, Liu S, Chen X, Huang R, Ma L, Weng H, Yu Y, Zong X
NPJ breast cancer 2021 Oct 7;7(1):132
NPJ breast cancer 2021 Oct 7;7(1):132
Naringenin attenuates endoplasmic reticulum stress, reduces apoptosis, and improves functional recovery in experimental traumatic brain injury.
Deng C, Yi R, Fei M, Li T, Han Y, Wang H
Brain research 2021 Oct 15;1769:147591
Brain research 2021 Oct 15;1769:147591
Targeting GRP78 enhances the sensitivity of HOS osteosarcoma cells to pyropheophorbide-α methyl ester-mediated photodynamic therapy via the Wnt/β-catenin signaling pathway.
Zuo Q, Ou Y, Zhong S, Yu H, Zhan F, Zhang M
Acta biochimica et biophysica Sinica 2021 Oct 12;53(10):1387-1397
Acta biochimica et biophysica Sinica 2021 Oct 12;53(10):1387-1397
Cytotoxic BODIPY-Appended Half-Sandwich Iridium(III) Complex Forms Protein Adducts and Induces ER Stress.
Ramos R, Gilles JF, Morichon R, Przybylski C, Caron B, Botuha C, Karaiskou A, Salmain M, Sobczak-Thépot J
Journal of medicinal chemistry 2021 Nov 25;64(22):16675-16686
Journal of medicinal chemistry 2021 Nov 25;64(22):16675-16686
2-Amino-3-Methylimidazo[4,5-f]quinoline Triggering Liver Damage by Inhibiting Autophagy and Inducing Endoplasmic Reticulum Stress in Zebrafish (Danio rerio).
Li D, Li Z, Zhang T, Peng B, Zhang Y, Sun H, Wang S
Toxins 2021 Nov 22;13(11)
Toxins 2021 Nov 22;13(11)
SAA1 is transcriptionally activated by STAT3 and accelerates renal interstitial fibrosis by inducing endoplasmic reticulum stress.
Zhang F, Zhou X, Zou H, Liu L, Li X, Ruan Y, Xie Y, Shi M, Xiao Y, Wang Y, Zhou Y, Wu Y, Guo B
Experimental cell research 2021 Nov 1;408(1):112856
Experimental cell research 2021 Nov 1;408(1):112856
The seed oil of Paeonia ludlowii ameliorates Aβ25-35-induced Alzheimer's disease in rats.
Lu YZ, Zhang CQ, Yu BX, Zhang EH, Quan H, Yin X, Cai H, Yuan F, Li LQ, Xu YJ, Su YJ, Xing YJ, Liao ZH, Lan XZ
Food science & nutrition 2021 May;9(5):2402-2413
Food science & nutrition 2021 May;9(5):2402-2413
Macrophage-derived exosomes mediate silica-induced pulmonary fibrosis by activating fibroblast in an endoplasmic reticulum stress-dependent manner.
Qin X, Lin X, Liu L, Li Y, Li X, Deng Z, Chen H, Chen H, Niu Z, Li Z, Hu Y
Journal of cellular and molecular medicine 2021 May;25(9):4466-4477
Journal of cellular and molecular medicine 2021 May;25(9):4466-4477
Roles of endoplasmic reticulum stress in 2,2',4,4'-tetrabromodiphenylether-induced thyroid cell apoptosis and autophagy.
Ma R, Li B, Zhang C, Lei R, Zhang X, Wang C, Zhang S, Wang A
Ecotoxicology and environmental safety 2021 May;214:112077
Ecotoxicology and environmental safety 2021 May;214:112077
PGE2 Released by Pancreatic Cancer Cells Undergoing ER Stress Transfers the Stress to DCs Impairing Their Immune Function.
Gilardini Montani MS, Benedetti R, Piconese S, Pulcinelli FM, Timperio AM, Romeo MA, Masuelli L, Mattei M, Bei R, D'Orazi G, Cirone M
Molecular cancer therapeutics 2021 May;20(5):934-945
Molecular cancer therapeutics 2021 May;20(5):934-945
SMYD3-PARP16 axis accelerates unfolded protein response and mediates neointima formation.
Long F, Yang D, Wang J, Wang Q, Ni T, Wei G, Zhu Y, Liu X
Acta pharmaceutica Sinica. B 2021 May;11(5):1261-1273
Acta pharmaceutica Sinica. B 2021 May;11(5):1261-1273
Heme cytotoxicity is the consequence of endoplasmic reticulum stress in atherosclerotic plaque progression.
Pethő D, Hendrik Z, Nagy A, Beke L, Patsalos A, Nagy L, Póliska S, Méhes G, Tóth C, Potor L, Eaton JW, Jacob HS, Balla G, Balla J, Gáll T
Scientific reports 2021 May 17;11(1):10435
Scientific reports 2021 May 17;11(1):10435
The role of ATF6 in Cr(VI)-induced apoptosis in DF-1 cells.
Zhang S, Zhao X, Hao J, Zhu Y, Wang Y, Wang L, Guo S, Yi H, Liu Y, Liu J
Journal of hazardous materials 2021 May 15;410:124607
Journal of hazardous materials 2021 May 15;410:124607
Sirtuin 6 ameliorates alcohol-induced liver injury by reducing endoplasmic reticulum stress in mice.
Xin Y, Xu L, Zhang X, Yang C, Wang Q, Xiong X
Biochemical and biophysical research communications 2021 Mar 12;544:44-51
Biochemical and biophysical research communications 2021 Mar 12;544:44-51
Ubiquitin-proteasome System Is a Promising Target for Killing Cisplatin-resistant Bladder Cancer Cells.
Okubo K, Isono M, Asano T, REßING N, Schulz WA, Hansen FK, Sato A
Anticancer research 2021 Jun;41(6):2901-2912
Anticancer research 2021 Jun;41(6):2901-2912
Lipotoxicity suppresses the synthesis of growth hormone in pituitary somatotrophs via endoplasmic reticulum stress.
Gong Y, Yang J, Wei S, Yang R, Gao L, Shao S, Zhao J
Journal of cellular and molecular medicine 2021 Jun;25(11):5250-5259
Journal of cellular and molecular medicine 2021 Jun;25(11):5250-5259
Characterization of a complex phenotype (fever-dependent recurrent acute liver failure and osteogenesis imperfecta) due to NBAS and P4HB variants.
Cotrina-Vinagre FJ, Rodríguez-García ME, Martín-Hernández E, Durán-Aparicio C, Merino-López A, Medina-Benítez E, Martínez-Azorín F
Molecular genetics and metabolism 2021 Jun;133(2):201-210
Molecular genetics and metabolism 2021 Jun;133(2):201-210
Endoplasmic reticulum stress manipulates autophagic response that antagonizes polybrominated diphenyl ethers quinone induced cytotoxicity in microglial BV2 cells.
Zhu Q, Liu Z, Wang Y, Song E, Song Y
Journal of hazardous materials 2021 Jun 5;411:124958
Journal of hazardous materials 2021 Jun 5;411:124958
Trim21-mediated HIF-1α degradation attenuates aerobic glycolysis to inhibit renal cancer tumorigenesis and metastasis.
Chen X, Li Z, Yong H, Wang W, Wang D, Chu S, Li M, Hou P, Zheng J, Bai J
Cancer letters 2021 Jun 28;508:115-126
Cancer letters 2021 Jun 28;508:115-126
Neutrophil extracellular traps impair intestinal barrier functions in sepsis by regulating TLR9-mediated endoplasmic reticulum stress pathway.
Sun S, Duan Z, Wang X, Chu C, Yang C, Chen F, Wang D, Wang C, Li Q, Ding W
Cell death & disease 2021 Jun 11;12(6):606
Cell death & disease 2021 Jun 11;12(6):606
The mechanism of 5-aminolevulinic acid photodynamic therapy in promoting endoplasmic reticulum stress in the treatment of HR-HPV-infected HeLa cells.
Li Z, Teng M, Wang Y, Wang Q, Feng Y, Xiao Z, Li C, Zeng K
Photodermatology, photoimmunology & photomedicine 2021 Jul;37(4):348-359
Photodermatology, photoimmunology & photomedicine 2021 Jul;37(4):348-359
Polybrominated diphenyl ethers quinone-induced intracellular protein oxidative damage triggers ubiquitin-proteasome and autophagy-lysosomal system activation in LO2 cells.
Wang Y, Xu L, Peng L, Fang C, Qin Q, Lv X, Liu Z, Yang B, Song E, Song Y
Chemosphere 2021 Jul;275:130034
Chemosphere 2021 Jul;275:130034
Choline attenuates heat stress-induced oxidative injury and apoptosis in bovine mammary epithelial cells by modulating PERK/Nrf-2 signaling pathway.
Yang M, Kuang M, Wang G, Ali I, Tang Y, Yang C, Li Y, Li L
Molecular immunology 2021 Jul;135:388-397
Molecular immunology 2021 Jul;135:388-397
Untargeted metabolomics and transcriptomics identified glutathione metabolism disturbance and PCS and TMAO as potential biomarkers for ER stress in lung.
Wang Z, Ma P, Wang Y, Hou B, Zhou C, Tian H, Li B, Shui G, Yang X, Qiang G, Yin C, Du G
Scientific reports 2021 Jul 19;11(1):14680
Scientific reports 2021 Jul 19;11(1):14680
Thrombospondin 1-induced exosomal proteins attenuate hypoxia-induced paraptosis in corneal epithelial cells and promote wound healing.
Lai YH, Lee PY, Lu CY, Liu YR, Wang SC, Liu CC, Chang YC, Chen YH, Su CC, Li CY, Liu PL
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Jan;35(1):e21200
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Jan;35(1):e21200
Autophagy impairment as a key feature for acetaminophen-induced ototoxicity.
Zhao T, Zheng T, Yu H, Hu BH, Hu B, Ma P, Yang Y, Yang N, Hu J, Cao T, Chen G, Yan B, Peshoff M, Hatzoglou M, Geng R, Li B, Zheng QY
Cell death & disease 2021 Jan 4;12(1):3
Cell death & disease 2021 Jan 4;12(1):3
Bioactivation of clozapine by mitochondria of the murine heart: Possible cause of cardiotoxicity.
Arzuk E, Karakuş F, Orhan H
Toxicology 2021 Jan 15;447:152628
Toxicology 2021 Jan 15;447:152628
MicroRNA-150 affects endoplasmic reticulum stress via MALAT1-miR-150 axis-mediated NF-κB pathway in LPS-challenged HUVECs and septic mice.
Liu L, Yan LN, Sui Z
Life sciences 2021 Jan 15;265:118744
Life sciences 2021 Jan 15;265:118744
Microcystin-leucine arginine induced the apoptosis of GnRH neurons by activating the endoplasmic reticulum stress resulting in a decrease of serum testosterone level in mice.
Jin H, Hou J, Meng X, Ma T, Wang B, Liu Z, Sha X, Ding J, Han X
Ecotoxicology and environmental safety 2021 Jan 15;208:111748
Ecotoxicology and environmental safety 2021 Jan 15;208:111748
Activation of the G Protein-Coupled Estrogen Receptor Prevented the Development of Acute Colitis by Protecting the Crypt Cell.
Wang Q, Li Z, Liu K, Liu J, Chai S, Chen G, Wen S, Ming T, Wang J, Ma Y, Zeng H, Liu C, Xue B
The Journal of pharmacology and experimental therapeutics 2021 Feb;376(2):281-293
The Journal of pharmacology and experimental therapeutics 2021 Feb;376(2):281-293
Boron Attenuates Heat Stress-Induced Apoptosis by Inhibiting Endoplasmic Reticulum Stress in Mouse Granulosa Cells.
Xiong Y, Jin E, Yin Q, Che C, He S
Biological trace element research 2021 Feb;199(2):611-621
Biological trace element research 2021 Feb;199(2):611-621
Central role of TRAP1 in the ameliorative effect of oleanolic acid on the mitochondrial-mediated and endoplasmic reticulum stress-excitated apoptosis induced by ochratoxin A.
Zhang Q, Chen W, Zhang B, Li C, Zhang X, Wang Q, Wang Y, Zhou Q, Li X, Shen XL
Toxicology 2021 Feb 28;450:152681
Toxicology 2021 Feb 28;450:152681
Receptor-Mediated ER Export of Lipoproteins Controls Lipid Homeostasis in Mice and Humans.
Wang X, Wang H, Xu B, Huang D, Nie C, Pu L, Zajac GJM, Yan H, Zhao J, Shi F, Emmer BT, Lu J, Wang R, Dong X, Dai J, Zhou W, Wang C, Gao G, Wang Y, Willer C, Lu X, Zhu Y, Chen XW
Cell metabolism 2021 Feb 2;33(2):350-366.e7
Cell metabolism 2021 Feb 2;33(2):350-366.e7
A point mutation in the Pdia6 gene results in loss of pancreatic β-cell identity causing overt diabetes.
Chhabra NF, Amend AL, Bastidas-Ponce A, Sabrautzki S, Tarquis-Medina M, Sachs S, Rubey M, Lorenz-Depiereux B, Feuchtinger A, Bakhti M, Lickert H, Przemeck GKH, Hrabě de Angelis M
Molecular metabolism 2021 Dec;54:101334
Molecular metabolism 2021 Dec;54:101334
Endoplasmic reticulum stress pathway mediates T-2 toxin-induced chondrocyte apoptosis.
Liu YN, Mu YD, Wang H, Zhang M, Shi YW, Mi G, Peng LX, Chen JH
Toxicology 2021 Dec;464:152989
Toxicology 2021 Dec;464:152989
The Dual Histone Deacetylase-Proteasome Inhibitor RTS-V5 Acts Synergistically With Ritonavir to Induce Endoplasmic Reticulum Stress in Bladder Cancer Cells.
Okubo K, REßING N, Schulz WA, Hansen FK, Asano T, Sato A
Anticancer research 2021 Dec;41(12):5987-5996
Anticancer research 2021 Dec;41(12):5987-5996
Non-canonical activation of the ER stress sensor ATF6 by Legionella pneumophila effectors.
Ibe NU, Subramanian A, Mukherjee S
Life science alliance 2021 Dec;4(12)
Life science alliance 2021 Dec;4(12)
ChREBP deficiency alleviates apoptosis by inhibiting TXNIP/oxidative stress in diabetic nephropathy.
Chen N, Song S, Yang Z, Wu M, Mu L, Zhou T, Shi Y
Journal of diabetes and its complications 2021 Dec;35(12):108050
Journal of diabetes and its complications 2021 Dec;35(12):108050
GJB1 mutations c.212T>G and c.311A>C induce apoptosis and inwardly rectifying potassium current changes in X-linked Charcot-Marie-Tooth type 1.
Guo H, Liu Y, Gu J, Luo J, Ma Y, Xiao F
Biochemical and biophysical research communications 2021 Dec 10;582:8-15
Biochemical and biophysical research communications 2021 Dec 10;582:8-15
Sulforaphane protects against oxidative stress‑induced apoptosis via activating SIRT1 in mouse osteoarthritis.
Chen M, Huang L, Lv Y, Li L, Dong Q
Molecular medicine reports 2021 Aug;24(2)
Molecular medicine reports 2021 Aug;24(2)
The ameliorative effect of terpinen-4-ol on ER stress-induced vascular calcification depends on SIRT1-mediated regulation of PERK acetylation.
Zhang Y, He L, Tu M, Huang M, Chen Y, Pan D, Peng J, Shen X
Pharmacological research 2021 Aug;170:105629
Pharmacological research 2021 Aug;170:105629
Integration of Metabolomics and Transcriptomics Reveals Ketone Body and Lipid Metabolism Disturbance Related to ER Stress in the Liver.
Ma P, Wang Z, Wang Y, Hou B, Sun J, Tian H, Li B, Shui G, Yang X, Yang X, Qiang G, Liew CW, Du G
Journal of proteome research 2021 Aug 6;20(8):3875-3888
Journal of proteome research 2021 Aug 6;20(8):3875-3888
TMEM41B acts as an ER scramblase required for lipoprotein biogenesis and lipid homeostasis.
Huang D, Xu B, Liu L, Wu L, Zhu Y, Ghanbarpour A, Wang Y, Chen FJ, Lyu J, Hu Y, Kang Y, Zhou W, Wang X, Ding W, Li X, Jiang Z, Chen J, Zhang X, Zhou H, Li JZ, Guo C, Zheng W, Zhang X, Li P, Melia T, Reinisch K, Chen XW
Cell metabolism 2021 Aug 3;33(8):1655-1670.e8
Cell metabolism 2021 Aug 3;33(8):1655-1670.e8
Ultrabright plasmonic fluor nanolabel-enabled detection of a urinary ER stress biomarker in autosomal dominant tubulointerstitial kidney disease.
Kim Y, Wang Z, Li C, Kidd K, Wang Y, Johnson BG, Kmoch S, Morrissey JJ, Bleyer AJ, Duffield JS, Singamaneni S, Chen YM
American journal of physiology. Renal physiology 2021 Aug 1;321(2):F236-F244
American journal of physiology. Renal physiology 2021 Aug 1;321(2):F236-F244
ARFGAP1 binds to classical swine fever virus NS5A protein and enhances CSFV replication in PK-15 cells.
Zhang L, Jin M, Song M, Liu S, Wang T, Guo K, Zhang Y
Veterinary microbiology 2021 Apr;255:109034
Veterinary microbiology 2021 Apr;255:109034
Changes in hepatic triglyceride content with the activation of ER stress and increased FGF21 secretion during pregnancy.
Lu J, Gong Y, Wei X, Yao Z, Yang R, Xin J, Gao L, Shao S
Nutrition & metabolism 2021 Apr 13;18(1):40
Nutrition & metabolism 2021 Apr 13;18(1):40
Glutamate-Cysteine Ligase Catalytic Subunit Attenuated Hepatitis C Virus-Related Liver Fibrosis and Suppressed Endoplasmic Reticulum Stress.
Fu N, Li D, Li W, Zhao W, Zhang S, Liu L, Zhao S, Du J, Kong L, Wang R, Zhang Y, Nan Y
Frontiers in molecular biosciences 2020;7:199
Frontiers in molecular biosciences 2020;7:199
Methane-Rich Saline Alleviates CA/CPR Brain Injury by Inhibiting Oxidative Stress, Microglial Activation-Induced Inflammatory Responses, and ER Stress-Mediated Apoptosis.
Cui R, Liu S, Wang C, Liu T, Ren J, Jia Y, Tong Y, Liu C, Zhang J
Oxidative medicine and cellular longevity 2020;2020:8829328
Oxidative medicine and cellular longevity 2020;2020:8829328
Therapeutic Role of Protein Tyrosine Phosphatase 1B in Parkinson's Disease via Antineuroinflammation and Neuroprotection In Vitro and In Vivo.
Feng CW, Chen NF, Chan TF, Chen WF
Parkinson's disease 2020;2020:8814236
Parkinson's disease 2020;2020:8814236
Diazoxide Protects against Myocardial Ischemia/Reperfusion Injury by Moderating ERS via Regulation of the miR-10a/IRE1 Pathway.
Zhang L, Cai S, Cao S, Nie J, Zhou W, Zhang Y, Li K, Wang H, Yu S, Yu T
Oxidative medicine and cellular longevity 2020;2020:4957238
Oxidative medicine and cellular longevity 2020;2020:4957238
Salvianolic Acid B Improves Chronic Mild Stress-Induced Depressive Behaviors in Rats: Involvement of AMPK/SIRT1 Signaling Pathway.
Liao D, Chen Y, Guo Y, Wang C, Liu N, Gong Q, Fu Y, Fu Y, Cao L, Yao D, Jiang P
Journal of inflammation research 2020;13:195-206
Journal of inflammation research 2020;13:195-206
Chlorin A-mediated photodynamic therapy induced apoptosis in human cholangiocarcinoma cells via impaired autophagy flux.
He C, Xia J, Gao Y, Chen Z, Wan X
American journal of translational research 2020;12(9):5080-5094
American journal of translational research 2020;12(9):5080-5094
Role of Endoplasmic Reticulum Stress in Otitis Media.
Zhao H, Wang Y, Li B, Zheng T, Liu X, Hu BH, Che J, Zhao T, Chen J, Hatzoglou M, Zhang X, Fan Z, Zheng Q
Frontiers in genetics 2020;11:495
Frontiers in genetics 2020;11:495
ANKS4B Restricts Replication of Zika Virus by Downregulating the Autophagy.
Lin Q, Zhou S, Huang Y, Huo Z, Chen C, Luo X, He J, Liu C, Zhang P
Frontiers in microbiology 2020;11:1745
Frontiers in microbiology 2020;11:1745
Maimendong Decoction Improves Pulmonary Function in Rats With Idiopathic Pulmonary Fibrosis by Inhibiting Endoplasmic Reticulum Stress in AECIIs.
Shen M, Nan Y, Zhang L, Di L, He S, Li Y, Li Y
Frontiers in pharmacology 2020;11:1262
Frontiers in pharmacology 2020;11:1262
A paralog-specific role of COPI vesicles in the neuronal differentiation of mouse pluripotent cells.
Jain Goyal M, Zhao X, Bozhinova M, Andrade-López K, de Heus C, Schulze-Dramac S, Müller-McNicoll M, Klumperman J, Béthune J
Life science alliance 2020 Sep;3(9)
Life science alliance 2020 Sep;3(9)
Asiatic acid ameliorates acute hepatic injury by reducing endoplasmic reticulum stress and triggering hepatocyte autophagy.
Pang X, Qiao Q, Vonglorkham S, Feng Z, Pang L, Chen S, Wang D, Lao L, Lin X, Wei J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Sep;129:110375
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Sep;129:110375
Reactive oxygen species mediate anlotinib-induced apoptosis via activation of endoplasmic reticulum stress in pancreatic cancer.
Yang L, Zhou X, Sun J, Lei Q, Wang Q, Pan D, Ding M, Ding Y
Cell death & disease 2020 Sep 17;11(9):766
Cell death & disease 2020 Sep 17;11(9):766
Liraglutide Up-regulation Thioredoxin Attenuated Müller Cells Apoptosis in High Glucose by Regulating Oxidative Stress and Endoplasmic Reticulum Stress.
Ren X, Sun L, Wei L, Liu J, Zhu J, Yu Q, Kong H, Kong L
Current eye research 2020 Oct;45(10):1283-1291
Current eye research 2020 Oct;45(10):1283-1291
ROS-mediated PERK-eIF2α-ATF4 pathway plays an important role in arsenite-induced L-02 cells apoptosis via regulating CHOP-DR5 signaling.
Liu C, Zhang A
Environmental toxicology 2020 Oct;35(10):1100-1113
Environmental toxicology 2020 Oct;35(10):1100-1113
Melatonin inhibits oxalate-induced endoplasmic reticulum stress and apoptosis in HK-2 cells by activating the AMPK pathway.
Song Q, He Z, Li B, Liu J, Liu L, Liao W, Xiong Y, Song C, Yang S, Liu Y
Cell cycle (Georgetown, Tex.) 2020 Oct;19(20):2600-2610
Cell cycle (Georgetown, Tex.) 2020 Oct;19(20):2600-2610
Neuroprotective mechanism of L-cysteine after subarachnoid hemorrhage.
Xiong Y, Xin DQ, Hu Q, Wang LX, Qiu J, Yuan HT, Chu XL, Liu DX, Li G, Wang Z
Neural regeneration research 2020 Oct;15(10):1920-1930
Neural regeneration research 2020 Oct;15(10):1920-1930
T-type calcium channel blockade induces apoptosis in C2C12 myotubes and skeletal muscle via endoplasmic reticulum stress activation.
Chen M, Li S, Hao M, Chen J, Zhao Z, Hong S, Min J, Tang J, Hu M, Hong L
FEBS open bio 2020 Oct;10(10):2122-2136
FEBS open bio 2020 Oct;10(10):2122-2136
IL-32 induces epithelial-mesenchymal transition by triggering endoplasmic reticulum stress in A549 cells.
Gong L, Liu G, Zhu H, Li C, Li P, Liu C, Tang H, Wu K, Wu J, Liu D, Tang X
BMC pulmonary medicine 2020 Oct 23;20(1):278
BMC pulmonary medicine 2020 Oct 23;20(1):278
Design, synthesis, and biological evaluation of 5-((8-methoxy-2-methylquinolin-4-yl)amino)-1H-indole-2-carbohydrazide derivatives as novel Nur77 modulators.
Li B, Yao J, Guo K, He F, Chen K, Lin Z, Liu S, Huang J, Wu Q, Fang M, Zeng J, Wu Z
European journal of medicinal chemistry 2020 Oct 15;204:112608
European journal of medicinal chemistry 2020 Oct 15;204:112608
Protective effects of pterostilbene against hepatic damage, redox imbalance, mitochondrial dysfunction, and endoplasmic reticulum stress in weanling piglets.
Zhang H, Chen Y, Li Y, Jia P, Ji S, Chen Y, Wang T
Journal of animal science 2020 Oct 1;98(10)
Journal of animal science 2020 Oct 1;98(10)
Aging is associated with increased TRB3, ER stress, and hepatic glucose production in the liver of rats.
Gaspar RC, Muñoz VR, Nakandakari SCBR, Vieira RFL, da Conceição LR, de Oliveira F, Crisol BM, da Silva ASR, Cintra DE, de Moura LP, Ropelle ER, Zaghloul I, Mekary RA, Pauli JR
Experimental gerontology 2020 Oct 1;139:111021
Experimental gerontology 2020 Oct 1;139:111021
Ubiquitin ligase CHIP regulates OTUD3 stability and suppresses tumour metastasis in lung cancer.
Zhang P, Li C, Li H, Yuan L, Dai H, Peng Z, Deng Z, Chang Z, Cui CP, Zhang L
Cell death and differentiation 2020 Nov;27(11):3177-3195
Cell death and differentiation 2020 Nov;27(11):3177-3195
CDK5RAP3, a Novel Nucleoplasmic Shuttle, Deeply Regulates HSF1-Mediated Heat Stress Response and Protects Mammary Epithelial Cells from Heat Injury.
Shen Y, Zou Y, Li J, Chen F, Li H, Cai Y
International journal of molecular sciences 2020 Nov 9;21(21)
International journal of molecular sciences 2020 Nov 9;21(21)
TRPV4 contributes to ER stress: Relation to apoptosis in the MPP(+)-induced cell model of Parkinson's disease.
Liu N, Liu J, Wen X, Bai L, Shao R, Bai J
Life sciences 2020 Nov 15;261:118461
Life sciences 2020 Nov 15;261:118461
Acupuncture protects against cerebral ischemia-reperfusion injury via suppressing endoplasmic reticulum stress-mediated autophagy and apoptosis.
Sun X, Liu H, Sun Z, Zhang B, Wang X, Liu T, Pan T, Gao Y, Jiang X, Li H
Molecular medicine (Cambridge, Mass.) 2020 Nov 10;26(1):105
Molecular medicine (Cambridge, Mass.) 2020 Nov 10;26(1):105
Cleavage of cyclic AMP-responsive element-binding protein H aggravates myocardial hypoxia reperfusion injury in a hepatocyte-myocardial cell co-culture system.
Jin Z, Chen Y, Weng X, Huang A, Lin S, Li H
The Journal of international medical research 2020 May;48(5):300060520904835
The Journal of international medical research 2020 May;48(5):300060520904835
Exogenous spermine attenuates rat diabetic cardiomyopathy via suppressing ROS-p53 mediated downregulation of calcium-sensitive receptor.
Wang Y, Chen J, Li S, Zhang X, Guo Z, Hu J, Shao X, Song N, Zhao Y, Li H, Yang G, Xu C, Wei C
Redox biology 2020 May;32:101514
Redox biology 2020 May;32:101514
Pyruvate alleviates high glucose-induced endoplasmic reticulum stress and apoptosis in HK-2 cells.
Zhang XM, Wang YZ, Tong JD, Ning XC, Zhou FQ, Yang XH, Jin HM
FEBS open bio 2020 May;10(5):827-834
FEBS open bio 2020 May;10(5):827-834
miR-384-5p promotes spinal cord injury recovery in rats through suppressing of autophagy and endoplasmic reticulum stress.
Zhou Z, Hu B, Lyu Q, Xie T, Wang J, Cai Q
Neuroscience letters 2020 May 14;727:134937
Neuroscience letters 2020 May 14;727:134937
Knockout of DNase1l1l abrogates lens denucleation process and causes cataract in zebrafish.
Zhang J, Cui WW, Du C, Huang Y, Pi X, Guo W, Wang J, Huang W, Chen D, Li J, Li H, Zhang J, Ma Y, Mu H, Zhang S, Liu M, Cui X, Hu Y
Biochimica et biophysica acta. Molecular basis of disease 2020 May 1;1866(5):165724
Biochimica et biophysica acta. Molecular basis of disease 2020 May 1;1866(5):165724
Xanthatin induces glioma cell apoptosis and inhibits tumor growth via activating endoplasmic reticulum stress-dependent CHOP pathway.
Ma YY, Di ZM, Cao Q, Xu WS, Bi SX, Yu JS, Shen YJ, Yu YQ, Shen YX, Feng LJ
Acta pharmacologica Sinica 2020 Mar;41(3):404-414
Acta pharmacologica Sinica 2020 Mar;41(3):404-414
Blockade of HSP70 by VER-155008 synergistically enhances bortezomib-induced cytotoxicity in multiple myeloma.
Huang L, Wang Y, Bai J, Yang Y, Wang F, Feng Y, Zhang R, Li F, Zhang P, Lv N, Lei L, Hu J, He A
Cell stress & chaperones 2020 Mar;25(2):357-367
Cell stress & chaperones 2020 Mar;25(2):357-367
Intrabody against prolyl hydroxylase 2 ameliorates acetaminophen-induced acute liver injury in mice via concomitant promotion of angiogenesis and redox homeostasis.
Zhao L, Zhao J, Gao R, Tian Y, Zhang Y, Tang W, Jiang Y, Li C, Wang M, Yang F, Li G
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Mar;123:109783
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Mar;123:109783
A novel splice site indel alteration in the EIF2AK3 gene is responsible for the first cases of Wolcott-Rallison syndrome in Hungary.
Sümegi A, Hendrik Z, Gáll T, Felszeghy E, Szakszon K, Antal-Szalmás P, Beke L, Papp Á, Méhes G, Balla J, Balla G
BMC medical genetics 2020 Mar 27;21(1):61
BMC medical genetics 2020 Mar 27;21(1):61
A light-triggered self-reinforced nanoagent for targeted chemo-photodynamic therapy of breast cancer bone metastases via ER stress and mitochondria mediated apoptotic pathways.
Huang Y, Xiao Z, Guan Z, Shen Y, Jiang Y, Xu X, Huang Z, Zhao C
Journal of controlled release : official journal of the Controlled Release Society 2020 Mar 10;319:119-134
Journal of controlled release : official journal of the Controlled Release Society 2020 Mar 10;319:119-134
Endoplasmic Reticulum Stress Signalling Induces Casein Kinase 1-Dependent Formation of Cytosolic TDP-43 Inclusions in Motor Neuron-Like Cells.
Hicks DA, Cross LL, Williamson R, Rattray M
Neurochemical research 2020 Jun;45(6):1354-1364
Neurochemical research 2020 Jun;45(6):1354-1364
Iodine‑125 seed radiation induces ROS‑mediated apoptosis, autophagy and paraptosis in human esophageal squamous cell carcinoma cells.
Wang C, Li TK, Zeng CH, Fan R, Wang Y, Zhu GY, Guo JH
Oncology reports 2020 Jun;43(6):2028-2044
Oncology reports 2020 Jun;43(6):2028-2044
Sulforaphane attenuates apoptosis of hippocampal neurons induced by high glucose via regulating endoplasmic reticulum.
Tang L, Ren X, Han Y, Chen L, Meng X, Zhang C, Chu H, Kong L, Ma H
Neurochemistry international 2020 Jun;136:104728
Neurochemistry international 2020 Jun;136:104728
Ubiquitin C-terminal hydrolase L1 (UCHL1) regulates post-myocardial infarction cardiac fibrosis through glucose-regulated protein of 78 kDa (GRP78).
Lei Q, Yi T, Li H, Yan Z, Lv Z, Li G, Wang Y
Scientific reports 2020 Jun 30;10(1):10604
Scientific reports 2020 Jun 30;10(1):10604
UBE2T promotes glioblastoma invasion and migration via stabilizing GRP78 and regulating EMT.
Huang P, Guo Y, Zhao Z, Ning W, Wang H, Gu C, Zhang M, Qu Y, Zhang H, Song Y
Aging 2020 Jun 3;12(11):10275-10289
Aging 2020 Jun 3;12(11):10275-10289
Excretory/secretory products of Angiostrongylus cantonensis fifth-stage larvae induce endoplasmic reticulum stress via the Sonic hedgehog pathway in mouse astrocytes.
Chen KY, Chen YJ, Cheng CJ, Jhan KY, Wang LC
Parasites & vectors 2020 Jun 18;13(1):317
Parasites & vectors 2020 Jun 18;13(1):317
Perinatal low-dose PBDE-47 exposure hampered thyroglobulin turnover and induced thyroid cell apoptosis by triggering ER stress and lysosomal destabilization contributing to thyroid toxicity in adult female rats.
Li P, Gao H, Dong L, Liu L, Zhou G, Luo C, Tian Z, Xia T, Wang A, Zhang S
Journal of hazardous materials 2020 Jun 15;392:122265
Journal of hazardous materials 2020 Jun 15;392:122265
Polychlorinated Biphenyl Quinone Promotes Atherosclerosis through Lipid Accumulation and Endoplasmic Reticulum Stress via CD36.
Yang B, Qin Q, Xu L, Lv X, Liu Z, Song E, Song Y
Chemical research in toxicology 2020 Jun 15;33(6):1497-1507
Chemical research in toxicology 2020 Jun 15;33(6):1497-1507
Non-Esterified Fatty Acid-Induced Reactive Oxygen Species Mediated Granulosa Cells Apoptosis Is Regulated by Nrf2/p53 Signaling Pathway.
Wang Y, Li C, Li J, Wang G, Li L
Antioxidants (Basel, Switzerland) 2020 Jun 14;9(6)
Antioxidants (Basel, Switzerland) 2020 Jun 14;9(6)
SHQ1 is an ER stress response gene that facilitates chemotherapeutics-induced apoptosis via sensitizing ER-stress response.
Liu H, Xie S, Fang F, Kalvakolanu DV, Xiao W
Cell death & disease 2020 Jun 10;11(6):445
Cell death & disease 2020 Jun 10;11(6):445
Circulating Exosomes From Lipopolysaccharide-Induced Ards Mice Trigger Endoplasmic Reticulum Stress in Lung Tissue.
Tang X, Yu Q, Wen X, Qi D, Peng J, He J, Deng W, Zhu T, Zhao Y, Wang D
Shock (Augusta, Ga.) 2020 Jul;54(1):110-118
Shock (Augusta, Ga.) 2020 Jul;54(1):110-118
Extracellular Vesicles Isolated from Human Induced Pluripotent Stem Cell-Derived Neurons Contain a Transcriptional Network.
Hicks DA, Jones AC, Corbett NJ, Fisher K, Pickering-Brown SM, Ashe MP, Hooper NM
Neurochemical research 2020 Jul;45(7):1711-1728
Neurochemical research 2020 Jul;45(7):1711-1728
Endosulfan induces endothelial inflammation and dysfunction via IRE1α/NF-κB signaling pathway.
Sun S, Ji Z, Fu J, Wang XF, Zhang LS
Environmental science and pollution research international 2020 Jul;27(21):26163-26171
Environmental science and pollution research international 2020 Jul;27(21):26163-26171
78 kDa Glucose-Regulated Protein Attenuates Protein Aggregation and Monocyte Adhesion Induced by Angiotensin II in Vascular Cells.
Cicalese S, Okuno K, Elliott KJ, Kawai T, Scalia R, Rizzo V, Eguchi S
International journal of molecular sciences 2020 Jul 15;21(14)
International journal of molecular sciences 2020 Jul 15;21(14)
Liraglutide protects pancreatic β cells from endoplasmic reticulum stress by upregulating MANF to promote autophagy turnover.
Fu J, Nchambi KM, Wu H, Luo X, An X, Liu D
Life sciences 2020 Jul 1;252:117648
Life sciences 2020 Jul 1;252:117648
Withaferin A triggers G2/M arrest and intrinsic apoptosis in glioblastoma cells via ATF4-ATF3-CHOP axis.
Tang Q, Ren L, Liu J, Li W, Zheng X, Wang J, Du G
Cell proliferation 2020 Jan;53(1):e12706
Cell proliferation 2020 Jan;53(1):e12706
Selenium Attenuates Chronic Heat Stress-Induced Apoptosis via the Inhibition of Endoplasmic Reticulum Stress in Mouse Granulosa Cells.
Xiong Y, Yin Q, Jin E, Chen H, He S
Molecules (Basel, Switzerland) 2020 Jan 28;25(3)
Molecules (Basel, Switzerland) 2020 Jan 28;25(3)
MCP-1 mediates ischemia-reperfusion-induced cardiomyocyte apoptosis via MCPIP1 and CaSR.
Zhang W, Zhu T, Chen L, Luo W, Chao J
American journal of physiology. Heart and circulatory physiology 2020 Jan 1;318(1):H59-H71
American journal of physiology. Heart and circulatory physiology 2020 Jan 1;318(1):H59-H71
Hydrogen sulfide regulates muscle RING finger-1 protein S-sulfhydration at Cys(44) to prevent cardiac structural damage in diabetic cardiomyopathy.
Sun X, Zhao D, Lu F, Peng S, Yu M, Liu N, Sun Y, Du H, Wang B, Chen J, Dong S, Lu F, Zhang W
British journal of pharmacology 2020 Feb;177(4):836-856
British journal of pharmacology 2020 Feb;177(4):836-856
Protective effect of Liraglutide on diabetic retinal neurodegeneration via inhibiting oxidative stress and endoplasmic reticulum stress.
Liu J, Wei L, Wang Z, Song S, Lin Z, Zhu J, Ren X, Kong L
Neurochemistry international 2020 Feb;133:104624
Neurochemistry international 2020 Feb;133:104624
Clinicopathological significance of endoplasmic reticulum stress proteins in ovarian carcinoma.
Samanta S, Tamura S, Dubeau L, Mhawech-Fauceglia P, Miyagi Y, Kato H, Lieberman R, Buckanovich RJ, Lin YG, Neamati N
Scientific reports 2020 Feb 7;10(1):2160
Scientific reports 2020 Feb 7;10(1):2160
Oxidative Stress and Endoplasmic Reticulum Stress Are Involved in the Protective Effect of Alpha Lipoic Acid Against Heat Damage in Chicken Testes.
Xiong Y, Yin Q, Li J, He S
Animals : an open access journal from MDPI 2020 Feb 27;10(3)
Animals : an open access journal from MDPI 2020 Feb 27;10(3)
Protection of retinal function and morphology in MNU-induced retinitis pigmentosa rats by ALDH2: an in-vivo study.
Yan W, Long P, Wei D, Yan W, Zheng X, Chen G, Wang J, Zhang Z, Chen T, Chen M
BMC ophthalmology 2020 Feb 18;20(1):55
BMC ophthalmology 2020 Feb 18;20(1):55
Hepatic DNAJB9 Drives Anabolic Biasing to Reduce Steatosis and Obesity.
Sun F, Liao Y, Qu X, Xiao X, Hou S, Chen Z, Huang H, Li P, Fu S
Cell reports 2020 Feb 11;30(6):1835-1847.e9
Cell reports 2020 Feb 11;30(6):1835-1847.e9
Fengbaisan suppresses endoplasmic reticulum stress by up-regulating SIRT1 expression to protect rats with chronic obstructive pulmonary diseases.
Wang Y, Su NX, Pan SG, Ge XP, Dai XP
Pharmaceutical biology 2020 Dec;58(1):878-885
Pharmaceutical biology 2020 Dec;58(1):878-885
NLRP3 inflammasome and endoplasmic reticulum stress in the epileptogenic zone in temporal lobe epilepsy: molecular insights into their interdependence.
Yue J, Wei YJ, Yang XL, Liu SY, Yang H, Zhang CQ
Neuropathology and applied neurobiology 2020 Dec;46(7):770-785
Neuropathology and applied neurobiology 2020 Dec;46(7):770-785
Zinc application alleviates the adverse renal effects of arsenic stress in a protein quality control way in common carp.
Wang Y, Zhao H, Nie X, Guo M, Jiang G, Xing M
Environmental research 2020 Dec;191:110063
Environmental research 2020 Dec;191:110063
Exogenous hydrogen sulfide inhibits apoptosis by regulating endoplasmic reticulum stress-autophagy axis and improves myocardial reconstruction after acute myocardial infarction.
Li Y, Liu M, Yi J, Song X, Zheng X, Liu D, Wang S, Chu C, Yang J
Acta biochimica et biophysica Sinica 2020 Dec 29;52(12):1325-1336
Acta biochimica et biophysica Sinica 2020 Dec 29;52(12):1325-1336
ALDH2 protects naturally aged mouse retina via inhibiting oxidative stress-related apoptosis and enhancing unfolded protein response in endoplasmic reticulum.
Long P, He M, Yan W, Chen W, Wei D, Wang S, Zhang Z, Ge W, Chen T
Aging 2020 Dec 19;13(2):2750-2767
Aging 2020 Dec 19;13(2):2750-2767
Cell cycle exit during bortezomib-induced osteogenic differentiation of mesenchymal stem cells was mediated by Xbp1s-upregulated p21(Cip1) and p27(Kip1).
Zhang D, Fan R, Lei L, Lei L, Wang Y, Lv N, Chen P, Williamson RA, Wang B, Hu J
Journal of cellular and molecular medicine 2020 Aug;24(16):9428-9438
Journal of cellular and molecular medicine 2020 Aug;24(16):9428-9438
Hydrogen sulphide ameliorating skeletal muscle atrophy in db/db mice via Muscle RING finger 1 S-sulfhydration.
Lu F, Lu B, Zhang L, Wen J, Wang M, Zhang S, Li Q, Shu F, Sun Y, Liu N, Peng S, Zhao Y, Dong S, Zhao D, Lu F, Zhang W
Journal of cellular and molecular medicine 2020 Aug;24(16):9362-9377
Journal of cellular and molecular medicine 2020 Aug;24(16):9362-9377
Proteomic Analysis Reveals Proteins and Pathways Associated with Lactation in Bovine Mammary Epithelial Cell-Derived Exosomes.
Zhang M, Ma Z, Li R, Guo S, Qiu Y, Gao X
Journal of proteome research 2020 Aug 7;19(8):3211-3219
Journal of proteome research 2020 Aug 7;19(8):3211-3219
FGF21 mitigates atherosclerosis via inhibition of NLRP3 inflammasome-mediated vascular endothelial cells pyroptosis.
Zeng Z, Zheng Q, Chen J, Tan X, Li Q, Ding L, Zhang R, Lin X
Experimental cell research 2020 Aug 15;393(2):112108
Experimental cell research 2020 Aug 15;393(2):112108
LncRNA GUARDIN suppresses cellular senescence through a LRP130-PGC1α-FOXO4-p21-dependent signaling axis.
Sun X, Thorne RF, Zhang XD, He M, Li J, Feng S, Liu X, Wu M
EMBO reports 2020 Apr 3;21(4):e48796
EMBO reports 2020 Apr 3;21(4):e48796
CACNA1H downregulation induces skeletal muscle atrophy involving endoplasmic reticulum stress activation and autophagy flux blockade.
Li S, Hao M, Li B, Chen M, Chen J, Tang J, Hong S, Min J, Hu M, Hong L
Cell death & disease 2020 Apr 24;11(4):279
Cell death & disease 2020 Apr 24;11(4):279
Exosomes from mesenchymal stem cells modulate endoplasmic reticulum stress to protect against nucleus pulposus cell death and ameliorate intervertebral disc degeneration in vivo.
Liao Z, Luo R, Li G, Song Y, Zhan S, Zhao K, Hua W, Zhang Y, Wu X, Yang C
Theranostics 2019;9(14):4084-4100
Theranostics 2019;9(14):4084-4100
GRP78 regulates milk biosynthesis and the proliferation of bovinemammaryepithelial cells through the mTOR signaling pathway.
Liu Y, Wang X, Zhen Z, Yu Y, Qiu Y, Xiang W
Cellular & molecular biology letters 2019;24:57
Cellular & molecular biology letters 2019;24:57
Unfolded Protein Response Pathways Correlatively Modulate Endoplasmic Reticulum Stress Responses in Rat Retinal Müller Cells.
Wu S, Zhu X, Guo B, Zheng T, Ren J, Zeng W, Chen X, Ke M
Journal of ophthalmology 2019;2019:9028483
Journal of ophthalmology 2019;2019:9028483
Betulinic Acid Suppresses Breast Cancer Metastasis by Targeting GRP78-Mediated Glycolysis and ER Stress Apoptotic Pathway.
Zheng Y, Liu P, Wang N, Wang S, Yang B, Li M, Chen J, Situ H, Xie M, Lin Y, Wang Z
Oxidative medicine and cellular longevity 2019;2019:8781690
Oxidative medicine and cellular longevity 2019;2019:8781690
UFL1 Alleviates Lipopolysaccharide-Induced Cell Damage and Inflammation via Regulation of the TLR4/NF-κB Pathway in Bovine Mammary Epithelial Cells.
Li C, Li L, Chen K, Wang Y, Yang F, Wang G
Oxidative medicine and cellular longevity 2019;2019:6505373
Oxidative medicine and cellular longevity 2019;2019:6505373
ZYZ-803 Mitigates Endoplasmic Reticulum Stress-Related Necroptosis after Acute Myocardial Infarction through Downregulating the RIP3-CaMKII Signaling Pathway.
Chang L, Wang Z, Ma F, Tran B, Zhong R, Xiong Y, Dai T, Wu J, Xin X, Guo W, Xie Y, Mao Y, Zhu YZ
Oxidative medicine and cellular longevity 2019;2019:6173685
Oxidative medicine and cellular longevity 2019;2019:6173685
Alpha-mangostin induces endoplasmic reticulum stress and autophagy which count against fatty acid synthase inhibition mediated apoptosis in human breast cancer cells.
Huang W, Liang Y, Ma X
Cancer cell international 2019;19:151
Cancer cell international 2019;19:151
The IRE1α-XBP1 pathway function in hypoxia-induced pulmonary vascular remodeling, is upregulated by quercetin, inhibits apoptosis and partially reverses the effect of quercetin in PASMCs.
Cao X, He Y, Li X, Xu Y, Liu X
American journal of translational research 2019;11(2):641-654
American journal of translational research 2019;11(2):641-654
Antimetastatic Effect of Fucoidan-Sargassum against Liver Cancer Cell Invadopodia Formation via Targeting Integrin αVβ3 and Mediating αVβ3/Src/E2F1 Signaling.
Pan TJ, Li LX, Zhang JW, Yang ZS, Shi DM, Yang YK, Wu WZ
Journal of Cancer 2019;10(20):4777-4792
Journal of Cancer 2019;10(20):4777-4792
Abnormal Glucose Metabolism and Insulin Resistance Are Induced via the IRE1α/XBP-1 Pathway in Subclinical Hypothyroidism.
Xu C, Zhou L, Wu K, Li Y, Xu J, Jiang D, Gao L
Frontiers in endocrinology 2019;10:303
Frontiers in endocrinology 2019;10:303
Vildagliptin Reduces Stenosis of Injured Carotid Artery in Diabetic Mouse Through Inhibiting Vascular Smooth Muscle Cell Proliferation via ER Stress/NF-κB Pathway.
Ji Y, Ge Y, Xu X, Ye S, Fan Y, Zhang J, Mei L, Zhang X, Ying L, Yang T, Li C
Frontiers in pharmacology 2019;10:142
Frontiers in pharmacology 2019;10:142
Correction to: Protective effects of dioscin against alcohol‑induced liver injury.
Xu T, Zheng L, Xu L, Yin L, Qi Y, Xu Y, Han X, Peng J
Archives of toxicology 2019 Sep;93(9):2713
Archives of toxicology 2019 Sep;93(9):2713
Regulatory role of Golgi brefeldin A resistance factor-1 in amyloid precursor protein trafficking, cleavage and Aβ formation.
Liu K, Liu Y, Xu Y, Nandakumar KS, Shen X, Lin J, Li C, He C, Zhou C
Journal of cellular biochemistry 2019 Sep;120(9):15604-15615
Journal of cellular biochemistry 2019 Sep;120(9):15604-15615
Mechanisms of IFNalpha-1a-Induced Apoptosis in a Laryngeal Cancer Cell Line.
Xin XL, Zhang R, Yuan XM, Liu L
Medical science monitor : international medical journal of experimental and clinical research 2019 Sep 22;25:7100-7114
Medical science monitor : international medical journal of experimental and clinical research 2019 Sep 22;25:7100-7114
BDE-209 induces autophagy and apoptosis via IRE1α/Akt/mTOR signaling pathway in human umbilical vein endothelial cells.
Hou Y, Fu J, Sun S, Jin Y, Wang X, Zhang L
Environmental pollution (Barking, Essex : 1987) 2019 Oct;253:429-438
Environmental pollution (Barking, Essex : 1987) 2019 Oct;253:429-438
Resveratrol reduces brain injury after subarachnoid hemorrhage by inhibiting oxidative stress and endoplasmic reticulum stress.
Xie YK, Zhou X, Yuan HT, Qiu J, Xin DQ, Chu XL, Wang DC, Wang Z
Neural regeneration research 2019 Oct;14(10):1734-1742
Neural regeneration research 2019 Oct;14(10):1734-1742
Suhuang antitussive capsule inhibits NLRP3 inflammasome activation and ameliorates pulmonary dysfunction via suppression of endoplasmic reticulum stress in cough variant asthma.
Qin W, Wu X, Jia Y, Tong X, Guo C, Chen D, Wang Z, Tan N
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109188
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109188
Niban protein regulates apoptosis in HK-2 cells via caspase-dependent pathway.
Tang S, Wang J, Liu J, Huang Y, Zhou Y, Yang S, Zhang W, Yang M, Zhang H
Renal failure 2019 Nov;41(1):455-466
Renal failure 2019 Nov;41(1):455-466
Lopinavir-Ritonavir Combination Induces Endoplasmic Reticulum Stress and Kills Urological Cancer Cells.
Okubo K, Isono M, Asano T, Sato A
Anticancer research 2019 Nov;39(11):5891-5901
Anticancer research 2019 Nov;39(11):5891-5901
Impaired calcium homeostasis via advanced glycation end products promotes apoptosis through endoplasmic reticulum stress in human nucleus pulposus cells and exacerbates intervertebral disc degeneration in rats.
Luo R, Song Y, Liao Z, Yin H, Zhan S, Wang K, Li S, Li G, Ma L, Lu S, Zhang Y, Yang C
The FEBS journal 2019 Nov;286(21):4356-4373
The FEBS journal 2019 Nov;286(21):4356-4373
Sevoflurane modulates AQPs (1,5) expression and endoplasmic reticulum stress in mice lung with allergic airway inflammation.
Lv CM, Wu HM, Wu L, Xu GH, Yang ZL, Shen QY
Bioscience reports 2019 Nov 29;39(11)
Bioscience reports 2019 Nov 29;39(11)
Inhibiting lysine 353 oxidation of GRP78 by a hypochlorous probe targeting endoplasmic reticulum promotes autophagy in cancer cells.
Ning J, Lin Z, Zhao X, Zhao B, Miao J
Cell death & disease 2019 Nov 12;10(11):858
Cell death & disease 2019 Nov 12;10(11):858
ER stress activation impairs the expression of circadian clock and clock-controlled genes in NIH3T3 cells via an ATF4-dependent mechanism.
Gao L, Chen H, Li C, Xiao Y, Yang D, Zhang M, Zhou D, Liu W, Wang A, Jin Y
Cellular signalling 2019 May;57:89-101
Cellular signalling 2019 May;57:89-101
Quantitative interaction proteomics reveals differences in the interactomes of amyloid precursor protein isoforms.
Andrew RJ, Fisher K, Heesom KJ, Kellett KAB, Hooper NM
Journal of neurochemistry 2019 May;149(3):399-412
Journal of neurochemistry 2019 May;149(3):399-412
Flaccidoxide-13-Acetate-Induced Apoptosis in Human Bladder Cancer Cells is through Activation of p38/JNK, Mitochondrial Dysfunction, and Endoplasmic Reticulum Stress Regulated Pathway.
Wu YJ, Su TR, Dai GF, Su JH, Liu CI
Marine drugs 2019 May 13;17(5)
Marine drugs 2019 May 13;17(5)
ERp29 counteracts the suppression of malignancy mediated by endoplasmic reticulum stress and promotes the metastasis of colorectal cancer.
Guo L, Ma L, Liu C, Lei Y, Tang N, Huang Y, Huang G, Li D, Wang Q, Liu G, Tang M, Jing Z, Deng Y
Oncology reports 2019 Mar;41(3):1603-1615
Oncology reports 2019 Mar;41(3):1603-1615
High-fat diet induces aberrant hepatic lipid secretion in blunt snout bream by activating endoplasmic reticulum stress-associated IRE1/XBP1 pathway.
Cao XF, Dai YJ, Liu MY, Yuan XY, Wang CC, Huang YY, Liu WB, Jiang GZ
Biochimica et biophysica acta. Molecular and cell biology of lipids 2019 Mar;1864(3):213-223
Biochimica et biophysica acta. Molecular and cell biology of lipids 2019 Mar;1864(3):213-223
Pharmacological preconditioning with the cellular stress inducer thapsigargin protects against experimental sepsis.
Wei Y, Meng M, Tian Z, Xie F, Yin Q, Dai C, Wang J, Zhang Q, Liu Y, Liu C, Yan F, Jiang F, Guo X
Pharmacological research 2019 Mar;141:114-122
Pharmacological research 2019 Mar;141:114-122
Low-concentration HCP1 inhibits apoptosis in vascular endothelial cells.
Wei Q, Zhang J, Su L, Zhao X, Zhao B, Miao J, Lin Z
Biochemical and biophysical research communications 2019 Mar 26;511(1):92-98
Biochemical and biophysical research communications 2019 Mar 26;511(1):92-98
Quantitative proteomic analysis of deer antler stem cells as a model of mammalian organ regeneration.
Dong Z, Coates D, Liu Q, Sun H, Li C
Journal of proteomics 2019 Mar 20;195:98-113
Journal of proteomics 2019 Mar 20;195:98-113
A Legionella pneumophila Kinase Phosphorylates the Hsp70 Chaperone Family to Inhibit Eukaryotic Protein Synthesis.
Moss SM, Taylor IR, Ruggero D, Gestwicki JE, Shokat KM, Mukherjee S
Cell host & microbe 2019 Mar 13;25(3):454-462.e6
Cell host & microbe 2019 Mar 13;25(3):454-462.e6
Cyclophilin B control of lysine post-translational modifications of skin type I collagen.
Terajima M, Taga Y, Cabral WA, Liu Y, Nagasawa M, Sumida N, Kayashima Y, Chandrasekaran P, Han L, Maeda N, Perdivara I, Hattori S, Marini JC, Yamauchi M
PLoS genetics 2019 Jun;15(6):e1008196
PLoS genetics 2019 Jun;15(6):e1008196
Exosomes from Microglia Attenuate Photoreceptor Injury and Neovascularization in an Animal Model of Retinopathy of Prematurity.
Xu W, Wu Y, Hu Z, Sun L, Dou G, Zhang Z, Wang H, Guo C, Wang Y
Molecular therapy. Nucleic acids 2019 Jun 7;16:778-790
Molecular therapy. Nucleic acids 2019 Jun 7;16:778-790
APS could potentially activate hepatic insulin signaling in HFD-induced IR mice.
Sun J, Liu Y, Yu J, Wu J, Gao W, Ran L, Jiang R, Guo M, Han D, Liu B, Wang N, Li Y, Huang H, Zeng L, Gao Y, Li X, Wu Y
Journal of molecular endocrinology 2019 Jul;63(1):77-91
Journal of molecular endocrinology 2019 Jul;63(1):77-91
Metformin induces TPC-1 cell apoptosis through endoplasmic reticulum stress-associated pathways in vitro and in vivo.
Ye J, Qi L, Chen K, Li R, Song S, Zhou C, Zhai W
International journal of oncology 2019 Jul;55(1):331-339
International journal of oncology 2019 Jul;55(1):331-339
Knockdown of TM9SF4 boosts ER stress to trigger cell death of chemoresistant breast cancer cells.
Zhu Y, Xie M, Meng Z, Leung LK, Chan FL, Hu X, Chi K, Liu C, Yao X
Oncogene 2019 Jul;38(29):5778-5791
Oncogene 2019 Jul;38(29):5778-5791
Ranolazine prevents pressure overload-induced cardiac hypertrophy and heart failure by restoring aberrant Na(+) and Ca(2+) handling.
Nie J, Duan Q, He M, Li X, Wang B, Zhou C, Wu L, Wen Z, Chen C, Wang DW, Alsina KM, Wehrens XHT, Wang DW, Ni L
Journal of cellular physiology 2019 Jul;234(7):11587-11601
Journal of cellular physiology 2019 Jul;234(7):11587-11601
c‑Jun N‑terminal kinase/transforming growth factor‑β/Smad3 pathway: Is it associated with endoplasmic reticulum stress‑mediated renal interstitial fibrosis?
Liu Y, Shen P, Zhou Y, Tang L, Chai H
Molecular medicine reports 2019 Jul;20(1):755-762
Molecular medicine reports 2019 Jul;20(1):755-762
Paneth cell ablation increases the small intestinal injury during acute necrotizing pancreatitis in rats.
Liu L, Guo Y, Zheng J, Lu Y, Shen Y, Huang C, Zeng Y, Wang X
Molecular medicine reports 2019 Jul;20(1):473-484
Molecular medicine reports 2019 Jul;20(1):473-484
The deubiquitylase OTUD3 stabilizes GRP78 and promotes lung tumorigenesis.
Du T, Li H, Fan Y, Yuan L, Guo X, Zhu Q, Yao Y, Li X, Liu C, Yu X, Liu Z, Cui CP, Han C, Zhang L
Nature communications 2019 Jul 2;10(1):2914
Nature communications 2019 Jul 2;10(1):2914
Induction of Endoplasmic Reticulum Stress by Cadmium and Its Regulation on Nrf2 Signaling Pathway in Kidneys of Rats.
Chen ZJ, Chen JX, Wu LK, Li BY, Tian YF, Xian M, Huang ZP, Yu RA
Biomedical and environmental sciences : BES 2019 Jan;32(1):1-10
Biomedical and environmental sciences : BES 2019 Jan;32(1):1-10
Co-downregulation of GRP78 and GRP94 Induces Apoptosis and Inhibits Migration in Prostate Cancer Cells.
Lu T, Wang Y, Xu K, Zhou Z, Gong J, Zhang Y, Gong H, Dai Q, Yang J, Xiong B, Song Z, Yang G
Open life sciences 2019 Jan;14:384-391
Open life sciences 2019 Jan;14:384-391
Autophagy activation alleviates nonylphenol-induced apoptosis in cultured cortical neurons.
Li S, Jiang Z, Chai W, Xu Y, Wang Y
Neurochemistry international 2019 Jan;122:73-84
Neurochemistry international 2019 Jan;122:73-84
Pterostilbene exerts a protective effect via regulating tunicamycin-induced endoplasmic reticulum stress in mouse preimplantation embryos.
Ullah O, Li Z, Ali I, Xu L, Liu H, Jin HZ, Fang YY, Jin QG, Fang N
In vitro cellular & developmental biology. Animal 2019 Feb;55(2):82-93
In vitro cellular & developmental biology. Animal 2019 Feb;55(2):82-93
MiR-451a suppressing BAP31 can inhibit proliferation and increase apoptosis through inducing ER stress in colorectal cancer.
Xu K, Han B, Bai Y, Ma XY, Ji ZN, Xiong Y, Miao SK, Zhang YY, Zhou LM
Cell death & disease 2019 Feb 15;10(3):152
Cell death & disease 2019 Feb 15;10(3):152
Mesencephalic astrocyte-derived neurotrophic factor (MANF) protects against Aβ toxicity via attenuating Aβ-induced endoplasmic reticulum stress.
Xu S, Di Z, He Y, Wang R, Ma Y, Sun R, Li J, Wang T, Shen Y, Fang S, Feng L, Shen Y
Journal of neuroinflammation 2019 Feb 13;16(1):35
Journal of neuroinflammation 2019 Feb 13;16(1):35
Chronic intermittent hypoxia accelerates liver fibrosis in rats with combined hypoxia and nonalcoholic steatohepatitis via angiogenesis rather than endoplasmic reticulum stress.
Wu W, Li W, Wei J, Wang C, Yao Y, Zhu W, He W, Zhou W, Liu J
Acta biochimica et biophysica Sinica 2019 Feb 1;51(2):159-167
Acta biochimica et biophysica Sinica 2019 Feb 1;51(2):159-167
Induction of the unfolded protein response (UPR) during pseudorabies virus infection.
Yang S, Zhu J, Zhou X, Wang H, Li X, Zhao A
Veterinary microbiology 2019 Dec;239:108485
Veterinary microbiology 2019 Dec;239:108485
Inhibition of CACNA1H attenuates doxorubicin-induced acute cardiotoxicity by affecting endoplasmic reticulum stress.
Hu J, Wu Q, Wang Z, Hong J, Chen R, Li B, Hu Z, Hu X, Zhang M
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109475
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109475
Signaling from mTOR to eIF2α mediates cell migration in response to the chemotherapeutic doxorubicin.
Harvey RF, Pöyry TAA, Stoneley M, Willis AE
Science signaling 2019 Dec 17;12(612)
Science signaling 2019 Dec 17;12(612)
Human placenta-derived mesenchymal stem cells inhibit apoptosis of granulosa cells induced by IRE1α pathway in autoimmune POF mice.
Li H, Zhao W, Wang L, Luo Q, Yin N, Lu X, Hou Y, Cui J, Zhang H
Cell biology international 2019 Aug;43(8):899-909
Cell biology international 2019 Aug;43(8):899-909
Bone marrow mesenchymal stem cells could reduce the toxic effects of hexavalent chromium on the liver by decreasing endoplasmic reticulum stress-mediated apoptosis via SIRT1/HIF-1α signaling pathway in rats.
Zhao Y, Yan J, Li AP, Zhang ZL, Li ZR, Guo KJ, Zhao KC, Ruan Q, Guo L
Toxicology letters 2019 Aug;310:31-38
Toxicology letters 2019 Aug;310:31-38
Proteomic analysis of retinal pigment epithelium cells after exposure to UVA radiation.
Chen JL, Hung CT, Keller JJ, Lin HC, Wu YJ
BMC ophthalmology 2019 Aug 2;19(1):168
BMC ophthalmology 2019 Aug 2;19(1):168
The IRE1 signaling pathway is involved in the protective effect of low-dose LPS on myocardial ischemia-reperfusion injury.
Wu T, Jiang N, Ji Z, Shi G
Life sciences 2019 Aug 15;231:116569
Life sciences 2019 Aug 15;231:116569
Protective effect of curcumin against irinotecan‑induced intestinal mucosal injury via attenuation of NF‑κB activation, oxidative stress and endoplasmic reticulum stress.
Ouyang M, Luo Z, Zhang W, Zhu D, Lu Y, Wu J, Yao X
International journal of oncology 2019 Apr;54(4):1376-1386
International journal of oncology 2019 Apr;54(4):1376-1386
Prion Protein Protects Cancer Cells against Endoplasmic Reticulum Stress Induced Apoptosis.
Gao Z, Peng M, Chen L, Yang X, Li H, Shi R, Wu G, Cai L, Song Q, Li C
Virologica Sinica 2019 Apr;34(2):222-234
Virologica Sinica 2019 Apr;34(2):222-234
Porcine Circovirus Type 2 Induces ORF3-Independent Mitochondrial Apoptosis via PERK Activation and Elevation of Cytosolic Calcium.
Zhang Y, Sun R, Geng S, Shan Y, Li X, Fang W
Journal of virology 2019 Apr 1;93(7)
Journal of virology 2019 Apr 1;93(7)
Differentially expressed genes of HepG2 cells treated with gecko polypeptide mixture.
Duan YM, Jin Y, Guo ML, Duan LX, Wang JG
Journal of Cancer 2018;9(15):2723-2733
Journal of Cancer 2018;9(15):2723-2733
Heme Induces Endoplasmic Reticulum Stress (HIER Stress) in Human Aortic Smooth Muscle Cells.
Gáll T, Pethő D, Nagy A, Hendrik Z, Méhes G, Potor L, Gram M, Åkerström B, Smith A, Nagy P, Balla G, Balla J
Frontiers in physiology 2018;9:1595
Frontiers in physiology 2018;9:1595
Salvianolic Acid A Attenuates Endoplasmic Reticulum Stress and Protects Against Cholestasis-Induced Liver Fibrosis via the SIRT1/HSF1 Pathway.
Zhu J, Wang R, Xu T, Zhang S, Zhao Y, Li Z, Wang C, Zhou J, Gao D, Hu Y, Tian X, Yao J
Frontiers in pharmacology 2018;9:1277
Frontiers in pharmacology 2018;9:1277
Impact of GADD34 on Apoptosis of Tonsillar Mononuclear Cells from IgA Nephropathy Patients by Regulating Eif2α Phosphorylation.
Peng X, Yang T, He L, Chen X, Jiang Y, Zhang H, Liu H, Peng Y
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;50(6):2203-2215
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;50(6):2203-2215
MnTMPyP inhibits paraquat-induced pulmonary epithelial-like cell injury by inhibiting oxidative stress.
Xu Y, Sun D, Song C, Wang R, Dong X
The Journal of toxicological sciences 2018;43(9):545-555
The Journal of toxicological sciences 2018;43(9):545-555
Neuroprotective Effects of dl-3-n-Butylphthalide against Doxorubicin-Induced Neuroinflammation, Oxidative Stress, Endoplasmic Reticulum Stress, and Behavioral Changes.
Liao D, Xiang D, Dang R, Xu P, Wang J, Han W, Fu Y, Yao D, Cao L, Jiang P
Oxidative medicine and cellular longevity 2018;2018:9125601
Oxidative medicine and cellular longevity 2018;2018:9125601
Methane-Rich Saline Ameliorates Sepsis-Induced Acute Kidney Injury through Anti-Inflammation, Antioxidative, and Antiapoptosis Effects by Regulating Endoplasmic Reticulum Stress.
Jia Y, Li Z, Feng Y, Cui R, Dong Y, Zhang X, Xiang X, Qu K, Liu C, Zhang J
Oxidative medicine and cellular longevity 2018;2018:4756846
Oxidative medicine and cellular longevity 2018;2018:4756846
Palmitic Acid Downregulates Thyroglobulin (Tg), Sodium Iodide Symporter (NIS), and Thyroperoxidase (TPO) in Human Primary Thyrocytes: A Potential Mechanism by Which Lipotoxicity Affects Thyroid?
Zhao M, Zhang X, Gao L, Song Y, Xu C, Yu C, Shao S, Zhao J
International journal of endocrinology 2018;2018:4215848
International journal of endocrinology 2018;2018:4215848
Proscillaridin A Promotes Oxidative Stress and ER Stress, Inhibits STAT3 Activation, and Induces Apoptosis in A549 Lung Adenocarcinoma Cells.
Maryam A, Mehmood T, Yan Q, Li Y, Khan M, Ma T
Oxidative medicine and cellular longevity 2018;2018:3853409
Oxidative medicine and cellular longevity 2018;2018:3853409
Glucagon-Like Peptide-1 Mediates the Protective Effect of the Dipeptidyl Peptidase IV Inhibitor on Renal Fibrosis via Reducing the Phenotypic Conversion of Renal Microvascular Cells in Monocrotaline-Treated Rats.
Xu J, Wang J, Cheng Y, Li X, He M, Zhu J, Han H, Wei G, Kong H, Xie W, Wang H, Zuo X
BioMed research international 2018;2018:1864107
BioMed research international 2018;2018:1864107
Vitamin C alters the amount of specific endoplasmic reticulum associated proteins involved in lipid metabolism in the liver of mice synthesizing a nonfunctional Werner syndrome (Wrn) mutant protein.
Aumailley L, Roux-Dalvai F, Kelly I, Droit A, Lebel M
PloS one 2018;13(3):e0193170
PloS one 2018;13(3):e0193170
UBIAD1 protects against oxygen-glucose deprivation/reperfusion-induced multiple subcellular organelles injury through PI3K/AKT pathway in N2A cells.
Huang Y, Hu Z
Journal of cellular physiology 2018 Sep;233(9):7480-7496
Journal of cellular physiology 2018 Sep;233(9):7480-7496
Amyotrophic lateral sclerosis (ALS) and Alzheimer's disease (AD) are characterised by differential activation of ER stress pathways: focus on UPR target genes.
Montibeller L, de Belleroche J
Cell stress & chaperones 2018 Sep;23(5):897-912
Cell stress & chaperones 2018 Sep;23(5):897-912
Ticagrelor protects against AngII-induced endothelial dysfunction by alleviating endoplasmic reticulum stress.
Wang X, Han X, Li M, Han Y, Zhang Y, Zhao S, Li Y
Microvascular research 2018 Sep;119:98-104
Microvascular research 2018 Sep;119:98-104
Selenoprotein S protects against adipocyte death through mediation of the IRE1α-sXBP1 pathway.
Men L, Yu S, Yao J, Li Y, Ren D, Du J
Biochemical and biophysical research communications 2018 Sep 18;503(4):2866-2871
Biochemical and biophysical research communications 2018 Sep 18;503(4):2866-2871
Phosphoglucomutase 1 inhibits hepatocellular carcinoma progression by regulating glucose trafficking.
Jin GZ, Zhang Y, Cong WM, Wu X, Wang X, Wu S, Wang S, Zhou W, Yuan S, Gao H, Yu G, Yang W
PLoS biology 2018 Oct;16(10):e2006483
PLoS biology 2018 Oct;16(10):e2006483
GanDouLing combined with Penicillamine improves cerebrovascular injury via PERK/eIF2α/CHOP endoplasmic reticulum stress pathway in the mouse model of Wilson's disease.
Chen Y, Zhang B, Cao S, Huang W, Liu N, Yang W
Bioscience reports 2018 Oct 31;38(5)
Bioscience reports 2018 Oct 31;38(5)
Tetrachlorobenzoquinone-Induced Nrf2 Confers Neuron-like PC12 Cells Resistance to Endoplasmic Reticulum Stress via Regulating Glutathione Synthesis and Protein Thiol Homeostasis.
Liu Z, Dong W, Yang B, Peng L, Xia X, Pu L, Zhang N, Song E, Song Y
Chemical research in toxicology 2018 Nov 19;31(11):1230-1239
Chemical research in toxicology 2018 Nov 19;31(11):1230-1239
Botulinum toxin B suppresses the pressure ulcer formation in cutaneous ischemia-reperfusion injury mouse model: Possible regulation of oxidative and endoplasmic reticulum stress.
Sekiguchi A, Motegi SI, Uchiyama A, Uehara A, Fujiwara C, Yamazaki S, Perera B, Nakamura H, Ogino S, Yokoyama Y, Akai R, Iwawaki T, Ishikawa O
Journal of dermatological science 2018 May;90(2):144-153
Journal of dermatological science 2018 May;90(2):144-153
A Novel Cx50 Insert Mutation from a Chinese Congenital Cataract Family Impairs Its Cellular Membrane Localization and Function.
Cui X, Zhou Z, Zhu K, Feng R, Han J, Li M, Wang S, Li J, Zhang J, Jiang Q, Zhang W, Mu H, Liu Y, Hu Y
DNA and cell biology 2018 May;37(5):449-456
DNA and cell biology 2018 May;37(5):449-456
Autophagy is a major mechanism for the dual effects of curcumin on renal cell carcinoma cells.
Deng Q, Liang L, Liu Q, Duan W, Jiang Y, Zhang L
European journal of pharmacology 2018 May 5;826:24-30
European journal of pharmacology 2018 May 5;826:24-30
Bcl-2 overexpression reduces cisplatin cytotoxicity by decreasing ER-mitochondrial Ca2+ signaling in SKOV3 cells.
Xu L, Xie Q, Qi L, Wang C, Xu N, Liu W, Yu Y, Li S, Xu Y
Oncology reports 2018 Mar;39(3):985-992
Oncology reports 2018 Mar;39(3):985-992
Effects of sevoflurane pretreatment on the apoptosis of rat H9c2 cardiomyocytes and the expression of GRP78.
Wang Z, Cui R, Wang K
Experimental and therapeutic medicine 2018 Mar;15(3):2818-2823
Experimental and therapeutic medicine 2018 Mar;15(3):2818-2823
Epigallocatechin-3-gallate alleviates bladder overactivity in a rat model with metabolic syndrome and ovarian hormone deficiency through mitochondria apoptosis pathways.
Lee YL, Lin KL, Wu BN, Chuang SM, Wu WJ, Lee YC, Ho WT, Juan YS
Scientific reports 2018 Mar 29;8(1):5358
Scientific reports 2018 Mar 29;8(1):5358
Advanced oxidation protein products aggravate cardiac remodeling via cardiomyocyte apoptosis in chronic kidney disease.
Feng W, Zhang K, Liu Y, Chen J, Cai Q, He W, Zhang Y, Wang MH, Wang J, Huang H
American journal of physiology. Heart and circulatory physiology 2018 Mar 1;314(3):H475-H483
American journal of physiology. Heart and circulatory physiology 2018 Mar 1;314(3):H475-H483
Serum vitamin C levels modulate the lifespan and endoplasmic reticulum stress response pathways in mice synthesizing a nonfunctional mutant WRN protein.
Aumailley L, Dubois MJ, Brennan TA, Garand C, Paquet ER, Pignolo RJ, Marette A, Lebel M
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2018 Jul;32(7):3623-3640
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2018 Jul;32(7):3623-3640
TRPV6 protects ER stress-induced apoptosis via ATF6α-TRPV6-JNK pathway in human embryonic stem cell-derived cardiomyocytes.
Li Z, Meng Z, Lu J, Chen FM, Wong WT, Tse G, Zheng C, Keung W, Tse K, Li RA, Jiang L, Yao X
Journal of molecular and cellular cardiology 2018 Jul;120:1-11
Journal of molecular and cellular cardiology 2018 Jul;120:1-11
ER-localized protein-Herpud1 is a new mediator of IL-4-induced macrophage polarization and migration.
Li Y, Xie Y, Hao J, Liu J, Ning Y, Tang Q, Ma M, Zhou H, Guan S, Zhou Q, Lv X
Experimental cell research 2018 Jul 15;368(2):167-173
Experimental cell research 2018 Jul 15;368(2):167-173
PGK1 and GRP78 overexpression correlates with clinical significance and poor prognosis in Chinese endometrial cancer patients.
Guo S, Xiao Y, Li D, Jiang Q, Zhu L, Lin D, Jiang H, Chen W, Wang L, Liu C, Fang W, Lin L
Oncotarget 2018 Jan 2;9(1):680-690
Oncotarget 2018 Jan 2;9(1):680-690
Brucella induces unfolded protein response and inflammatory response via GntR in alveolar macrophages.
Zhou D, Zhi FJ, Qi MZ, Bai FR, Zhang G, Li JM, Liu H, Chen HT, Lin PF, Tang KQ, Liu W, Jin YP, Wang AH
Oncotarget 2018 Jan 12;9(4):5184-5196
Oncotarget 2018 Jan 12;9(4):5184-5196
Excessive ER stress and the resulting autophagic flux dysfunction contribute to fluoride-induced neurotoxicity.
Niu Q, Chen J, Xia T, Li P, Zhou G, Xu C, Zhao Q, Dong L, Zhang S, Wang A
Environmental pollution (Barking, Essex : 1987) 2018 Feb;233:889-899
Environmental pollution (Barking, Essex : 1987) 2018 Feb;233:889-899
Young plasma reverses age-dependent alterations in hepatic function through the restoration of autophagy.
Liu A, Guo E, Yang J, Yang Y, Liu S, Jiang X, Hu Q, Dirsch O, Dahmen U, Zhang C, Gewirtz DA, Fang H
Aging cell 2018 Feb;17(1)
Aging cell 2018 Feb;17(1)
Protective Effects of Olive Leaf Extract on Acrolein-Exacerbated Myocardial Infarction via an Endoplasmic Reticulum Stress Pathway.
Xu Y, Wu L, Chen A, Xu C, Feng Q
International journal of molecular sciences 2018 Feb 7;19(2)
International journal of molecular sciences 2018 Feb 7;19(2)
Asiatic acid from Potentilla chinensis alleviates non-alcoholic fatty liver by regulating endoplasmic reticulum stress and lipid metabolism.
Wang D, Lao L, Pang X, Qiao Q, Pang L, Feng Z, Bai F, Sun X, Lin X, Wei J
International immunopharmacology 2018 Dec;65:256-267
International immunopharmacology 2018 Dec;65:256-267
Hepatic Mitochondrial Defects in a Nonalcoholic Fatty Liver Disease Mouse Model Are Associated with Increased Degradation of Oxidative Phosphorylation Subunits.
Lee K, Haddad A, Osme A, Kim C, Borzou A, Ilchenko S, Allende D, Dasarathy S, McCullough A, Sadygov RG, Kasumov T
Molecular & cellular proteomics : MCP 2018 Dec;17(12):2371-2386
Molecular & cellular proteomics : MCP 2018 Dec;17(12):2371-2386
Perigestational exposure to low doses of PBDE-47 induces excessive ER stress, defective autophagy and the resultant apoptosis contributing to maternal thyroid toxicity.
Li P, Liu L, Zhou G, Tian Z, Luo C, Xia T, Chen J, Niu Q, Dong L, Zhao Q, Wang A, Zhang S
The Science of the total environment 2018 Dec 15;645:363-371
The Science of the total environment 2018 Dec 15;645:363-371
Mini-peptide RPL41 attenuated retinal neovascularization by inducing degradation of ATF4 in oxygen-induced retinopathy mice.
Geng W, Qin F, Ren J, Xiao S, Wang A
Experimental cell research 2018 Aug 15;369(2):243-250
Experimental cell research 2018 Aug 15;369(2):243-250
CHOP induces apoptosis by affecting brain iron metabolism in rats with subarachnoid hemorrhage.
Zhao J, Xiang X, Zhang H, Jiang D, Liang Y, Qing W, Liu L, Zhao Q, He Z
Experimental neurology 2018 Apr;302:22-33
Experimental neurology 2018 Apr;302:22-33
Downregulation of reticulocalbin-1 differentially facilitates apoptosis and necroptosis in human prostate cancer cells.
Liu X, Zhang N, Wang D, Zhu D, Yuan Q, Zhang X, Qian L, Niu H, Lu Y, Ren G, Tian K, Yuan H
Cancer science 2018 Apr;109(4):1147-1157
Cancer science 2018 Apr;109(4):1147-1157
Hepatic loss of Lissencephaly 1 (Lis1) induces fatty liver and accelerates liver tumorigenesis in mice.
Li X, Liu L, Li R, Wu A, Lu J, Wu Q, Jia J, Zhao M, Song H
The Journal of biological chemistry 2018 Apr 6;293(14):5160-5171
The Journal of biological chemistry 2018 Apr 6;293(14):5160-5171
Exogenous H(2)S restores ischemic post-conditioning-induced cardioprotection through inhibiting endoplasmic reticulum stress in the aged cardiomyocytes.
Sun W, Yang J, Zhang Y, Xi Y, Wen X, Yuan D, Wang Y, Wei C, Wang R, Wu L, Li H, Xu C
Cell & bioscience 2017;7:67
Cell & bioscience 2017;7:67
Hydrogen Gas Attenuates Myocardial Ischemia Reperfusion Injury Independent of Postconditioning in Rats by Attenuating Endoplasmic Reticulum Stress-Induced Autophagy.
Gao Y, Yang H, Chi J, Xu Q, Zhao L, Yang W, Liu W, Yang W
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;43(4):1503-1514
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;43(4):1503-1514
Endoplasmic Reticulum Stress Is Involved in Cochlear Cell Apoptosis in a Cisplatin-Induced Ototoxicity Rat Model.
Zong S, Liu T, Wan F, Chen P, Luo P, Xiao H
Audiology & neuro-otology 2017;22(3):160-168
Audiology & neuro-otology 2017;22(3):160-168
TBHQ Alleviated Endoplasmic Reticulum Stress-Apoptosis and Oxidative Stress by PERK-Nrf2 Crosstalk in Methamphetamine-Induced Chronic Pulmonary Toxicity.
Wang Y, Gu YH, Liu M, Bai Y, Liang LY, Wang HL
Oxidative medicine and cellular longevity 2017;2017:4310475
Oxidative medicine and cellular longevity 2017;2017:4310475
Involvement of endoplasmic reticulum stress in formalin-induced pain is attenuated by 4-phenylbutyric acid.
Zhou F, Zhang W, Zhou J, Li M, Zhong F, Zhang Y, Liu Y, Wang Y
Journal of pain research 2017;10:653-662
Journal of pain research 2017;10:653-662
GRP78 plays an integral role in tumor cell inflammation-related migration induced by M2 macrophages.
Zhang L, Li Z, Ding G, La X, Yang P, Li Z
Cellular signalling 2017 Sep;37:136-148
Cellular signalling 2017 Sep;37:136-148
The meta and bioinformatics analysis of GRP78 expression in gastric cancer.
Zheng HC, Gong BC, Zhao S
Oncotarget 2017 Sep 22;8(42):73017-73028
Oncotarget 2017 Sep 22;8(42):73017-73028
Inhibition of Endoplasmic Reticulum Stress Alleviates Lung Injury Induced by Brain Death.
Tang H, Zhang J, Cao S, Yan B, Fang H, Zhang H, Guo W, Zhang S
Inflammation 2017 Oct;40(5):1664-1671
Inflammation 2017 Oct;40(5):1664-1671
CNPY2 is a key initiator of the PERK-CHOP pathway of the unfolded protein response.
Hong F, Liu B, Wu BX, Morreall J, Roth B, Davies C, Sun S, Diehl JA, Li Z
Nature structural & molecular biology 2017 Oct;24(10):834-839
Nature structural & molecular biology 2017 Oct;24(10):834-839
Therapeutic effects of L-Cysteine in newborn mice subjected to hypoxia-ischemia brain injury via the CBS/H(2)S system: Role of oxidative stress and endoplasmic reticulum stress.
Liu S, Xin D, Wang L, Zhang T, Bai X, Li T, Xie Y, Xue H, Bo S, Liu D, Wang Z
Redox biology 2017 Oct;13:528-540
Redox biology 2017 Oct;13:528-540
Thioredoxin is implicated in the anti‑apoptotic effects of grape seed proanthocyanidin extract during hyperglycemia.
Ren X, Lu H, Wang N, Zhang C, Ji Y, Cui S, Dong Y, Yang K, Du M, Diao F, Kong L
Molecular medicine reports 2017 Nov;16(5):7731-7737
Molecular medicine reports 2017 Nov;16(5):7731-7737
Hepatitis B virus X protein inhibits apoptosis by modulating endoplasmic reticulum stress response.
Li J, He J, Fu Y, Hu X, Sun LQ, Huang Y, Fan X
Oncotarget 2017 Nov 10;8(56):96027-96034
Oncotarget 2017 Nov 10;8(56):96027-96034
PCSK9 regulates apoptosis in human lung adenocarcinoma A549 cells via endoplasmic reticulum stress and mitochondrial signaling pathways.
Xu X, Cui Y, Cao L, Zhang Y, Yin Y, Hu X
Experimental and therapeutic medicine 2017 May;13(5):1993-1999
Experimental and therapeutic medicine 2017 May;13(5):1993-1999
Renin-angiotensin system activation accelerates atherosclerosis in experimental renal failure by promoting endoplasmic reticulum stress-related inflammation.
Yang J, Zhang X, Yu X, Tang W, Gan H
International journal of molecular medicine 2017 Mar;39(3):613-621
International journal of molecular medicine 2017 Mar;39(3):613-621
Calcium release induced by 2-pyridinecarboxaldehyde thiosemicarbazone and its copper complex contributes to tumor cell death.
Fu Y, Liu Y, Wang J, Li C, Zhou S, Yang Y, Zhou P, Lu C, Li C
Oncology reports 2017 Mar;37(3):1662-1670
Oncology reports 2017 Mar;37(3):1662-1670
Identification of Novel SCIRR69-Interacting Proteins During ER Stress Using SILAC-Immunoprecipitation Quantitative Proteomics Approach.
Chen Y, Liu Y, Lin S, Yang S, Que H, Liu S
Neuromolecular medicine 2017 Mar;19(1):81-93
Neuromolecular medicine 2017 Mar;19(1):81-93
Exogenous H(2)S regulates endoplasmic reticulum-mitochondria cross-talk to inhibit apoptotic pathways in STZ-induced type I diabetes.
Yang F, Yu X, Li T, Wu J, Zhao Y, Liu J, Sun A, Dong S, Wu J, Zhong X, Xu C, Lu F, Zhang W
American journal of physiology. Endocrinology and metabolism 2017 Mar 1;312(3):E190-E203
American journal of physiology. Endocrinology and metabolism 2017 Mar 1;312(3):E190-E203
Cr(VI) induces cytotoxicity in vitro through activation of ROS-mediated endoplasmic reticulum stress and mitochondrial dysfunction via the PI3K/Akt signaling pathway.
Zhang Y, Xiao F, Liu X, Liu K, Zhou X, Zhong C
Toxicology in vitro : an international journal published in association with BIBRA 2017 Jun;41:232-244
Toxicology in vitro : an international journal published in association with BIBRA 2017 Jun;41:232-244
Curcumin enhances the effects of irinotecan on colorectal cancer cells through the generation of reactive oxygen species and activation of the endoplasmic reticulum stress pathway.
Huang YF, Zhu DJ, Chen XW, Chen QK, Luo ZT, Liu CC, Wang GX, Zhang WJ, Liao NZ
Oncotarget 2017 Jun 20;8(25):40264-40275
Oncotarget 2017 Jun 20;8(25):40264-40275
Cell surface GRP78 facilitates hepatoma cells proliferation and migration by activating IGF-IR.
Yin Y, Chen C, Chen J, Zhan R, Zhang Q, Xu X, Li D, Li M
Cellular signalling 2017 Jul;35:154-162
Cellular signalling 2017 Jul;35:154-162
Endoplasmic reticulum stress and apoptosis via PERK-eIF2α-CHOP signaling in the methamphetamine-induced chronic pulmonary injury.
Gu YH, Wang Y, Bai Y, Liu M, Wang HL
Environmental toxicology and pharmacology 2017 Jan;49:194-201
Environmental toxicology and pharmacology 2017 Jan;49:194-201
GALNT6 Stabilizes GRP78 Protein by O-glycosylation and Enhances its Activity to Suppress Apoptosis Under Stress Condition.
Lin J, Chung S, Ueda K, Matsuda K, Nakamura Y, Park JH
Neoplasia (New York, N.Y.) 2017 Jan;19(1):43-53
Neoplasia (New York, N.Y.) 2017 Jan;19(1):43-53
Knockdown of histidine-rich calcium-binding protein (HRC) suppresses liver fibrosis by inhibiting the activation of hepatic stellate cells.
Liu J, Li M, Gong J, Han P, Wang Y, Li D, Tian D, Liao J
Biology open 2017 Jan 15;6(1):29-34
Biology open 2017 Jan 15;6(1):29-34
A positive feedback loop between GRP78 and VPS34 is critical for GRP78-mediated autophagy in cancer cells.
Wang Y, Wu H, Li Z, Yang P, Li Z
Experimental cell research 2017 Feb 1;351(1):24-35
Experimental cell research 2017 Feb 1;351(1):24-35
Protective effect of mesenchymal stem cells on the pressure ulcer formation by the regulation of oxidative and endoplasmic reticulum stress.
Motegi SI, Sekiguchi A, Uchiyama A, Uehara A, Fujiwara C, Yamazaki S, Perera B, Nakamura H, Ogino S, Yokoyama Y, Akai R, Iwawaki T, Ishikawa O
Scientific reports 2017 Dec 7;7(1):17186
Scientific reports 2017 Dec 7;7(1):17186
Elevated urinary CRELD2 is associated with endoplasmic reticulum stress-mediated kidney disease.
Kim Y, Park SJ, Manson SR, Molina CA, Kidd K, Thiessen-Philbrook H, Perry RJ, Liapis H, Kmoch S, Parikh CR, Bleyer AJ, Chen YM
JCI insight 2017 Dec 7;2(23)
JCI insight 2017 Dec 7;2(23)
Autoantibodies against glucose-regulated protein 78 as serological biomarkers in metastatic and recurrent hepatocellular carcinoma.
Ying X, Han SX, He CC, Zhou CY, Dong YP, Cai MJ, Sui X, Ma CX, Sun X, Zhang YY, Gou WL, Mason C, Zhu Q
Oncotarget 2017 Apr 11;8(15):24828-24839
Oncotarget 2017 Apr 11;8(15):24828-24839
Quantitative Proteomic Profiling the Molecular Signatures of Annexin A5 in Lung Squamous Carcinoma Cells.
Sun B, Bai Y, Zhang L, Gong L, Qi X, Li H, Wang F, Chi X, Jiang Y, Shao S
PloS one 2016;11(9):e0163622
PloS one 2016;11(9):e0163622
A Health Threat to Bystanders Living in the Homes of Smokers: How Smoke Toxins Deposited on Surfaces Can Cause Insulin Resistance.
Adhami N, Starck SR, Flores C, Martins Green M
PloS one 2016;11(3):e0149510
PloS one 2016;11(3):e0149510
Dysfunctional tubular endoplasmic reticulum constitutes a pathological feature of Alzheimer's disease.
Sharoar MG, Shi Q, Ge Y, He W, Hu X, Perry G, Zhu X, Yan R
Molecular psychiatry 2016 Sep;21(9):1263-71
Molecular psychiatry 2016 Sep;21(9):1263-71
Activating Transcription Factor 4 (ATF4)-ATF3-C/EBP Homologous Protein (CHOP) Cascade Shows an Essential Role in the ER Stress-Induced Sensitization of Tetrachlorobenzoquinone-Challenged PC12 Cells to ROS-Mediated Apoptosis via Death Receptor 5 (DR5) Signaling.
Liu Z, Shi Q, Song X, Wang Y, Wang Y, Song E, Song Y
Chemical research in toxicology 2016 Sep 19;29(9):1510-8
Chemical research in toxicology 2016 Sep 19;29(9):1510-8
Hydrogen-rich saline mediates neuroprotection through the regulation of endoplasmic reticulum stress and autophagy under hypoxia-ischemia neonatal brain injury in mice.
Bai X, Liu S, Yuan L, Xie Y, Li T, Wang L, Wang X, Zhang T, Qin S, Song G, Ge L, Wang Z
Brain research 2016 Sep 1;1646:410-417
Brain research 2016 Sep 1;1646:410-417
Design, purification and assessment of GRP78 binding peptide-linked Subunit A of Subtilase cytotoxic for targeting cancer cells.
Zhang L, Li Z, Shi T, La X, Li H, Li Z
BMC biotechnology 2016 Sep 1;16(1):65
BMC biotechnology 2016 Sep 1;16(1):65
Palmitic acid aggravates inflammation of pancreatic acinar cells by enhancing unfolded protein response induced CCAAT-enhancer-binding protein β-CCAAT-enhancer-binding protein α activation.
Wu J, Hu G, Lu Y, Zheng J, Chen J, Wang X, Zeng Y
The international journal of biochemistry & cell biology 2016 Oct;79:181-193
The international journal of biochemistry & cell biology 2016 Oct;79:181-193
Chronic alpha-linolenic acid treatment alleviates age-associated neuropathology: Roles of PERK/eIF2α signaling pathway.
Gao H, Yan P, Zhang S, Nie S, Huang F, Han H, Deng Q, Huang Q, Yang W, Wu H, Yao P, Ye K, Xu J, Liu L
Brain, behavior, and immunity 2016 Oct;57:314-325
Brain, behavior, and immunity 2016 Oct;57:314-325
Rifampicin-induced injury in L02 cells is alleviated by 4-PBA via inhibition of the PERK-ATF4-CHOP pathway.
Zhang W, Chen L, Shen Y, Xu J
Toxicology in vitro : an international journal published in association with BIBRA 2016 Oct;36:186-196
Toxicology in vitro : an international journal published in association with BIBRA 2016 Oct;36:186-196
Cytotoxicity of 11-epi-Sinulariolide Acetate Isolated from Cultured Soft Corals on HA22T Cells through the Endoplasmic Reticulum Stress Pathway and Mitochondrial Dysfunction.
Lin JJ, Wang RY, Chen JC, Chiu CC, Liao MH, Wu YJ
International journal of molecular sciences 2016 Oct 27;17(11)
International journal of molecular sciences 2016 Oct 27;17(11)
Alpha-lipoic acid defends homocysteine-induced endoplasmic reticulum and oxidative stress in HAECs.
Hu H, Wang C, Jin Y, Meng Q, Liu Q, Liu K, Sun H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 May;80:63-72
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 May;80:63-72
Cyanidin 3-O-β-Glucoside Ameliorates Ethanol-Induced Acute Liver Injury by Attenuating Oxidative Stress and Apoptosis: The Role of SIRT1/FOXO1 Signaling.
Liu J, Zhou J, Wu Z, Wang X, Liu L, Yao C
Alcoholism, clinical and experimental research 2016 Mar;40(3):457-66
Alcoholism, clinical and experimental research 2016 Mar;40(3):457-66
Japanese encephalitis virus induces apoptosis by the IRE1/JNK pathway of ER stress response in BHK-21 cells.
Huang M, Xu A, Wu X, Zhang Y, Guo Y, Guo F, Pan Z, Kong L
Archives of virology 2016 Mar;161(3):699-703
Archives of virology 2016 Mar;161(3):699-703
Translation from the 5' untranslated region shapes the integrated stress response.
Starck SR, Tsai JC, Chen K, Shodiya M, Wang L, Yahiro K, Martins-Green M, Shastri N, Walter P
Science (New York, N.Y.) 2016 Jan 29;351(6272):aad3867
Science (New York, N.Y.) 2016 Jan 29;351(6272):aad3867
The ATF6 pathway of the ER stress response contributes to enhanced viability in glioblastoma.
Dadey DY, Kapoor V, Khudanyan A, Urano F, Kim AH, Thotala D, Hallahan DE
Oncotarget 2016 Jan 12;7(2):2080-92
Oncotarget 2016 Jan 12;7(2):2080-92
Effects of Placental Ischemia Are Attenuated by 1,25-Dihydroxyvitamin D Treatment and Associated with Reduced Apoptosis and Increased Autophagy.
Tian X, Ma S, Wang Y, Hou L, Shi Y, Yao M, Wang X, Zhang H, Jiang L
DNA and cell biology 2016 Feb;35(2):59-70
DNA and cell biology 2016 Feb;35(2):59-70
ABT737 reverses cisplatin resistance by regulating ER-mitochondria Ca2+ signal transduction in human ovarian cancer cells.
Xie Q, Su J, Jiao B, Shen L, Ma L, Qu X, Yu C, Jiang X, Xu Y, Sun L
International journal of oncology 2016 Dec;49(6):2507-2519
International journal of oncology 2016 Dec;49(6):2507-2519
Resveratrol Induces Cancer Cell Apoptosis through MiR-326/PKM2-Mediated ER Stress and Mitochondrial Fission.
Wu H, Wang Y, Wu C, Yang P, Li H, Li Z
Journal of agricultural and food chemistry 2016 Dec 14;64(49):9356-9367
Journal of agricultural and food chemistry 2016 Dec 14;64(49):9356-9367
Cathelicidin PR-39 peptide inhibits hypoxia/reperfusion-induced kidney cell apoptosis by suppression of the endoplasmic reticulum-stress pathway.
Liu J, Xue W, Xiang H, Zheng J, Zhao Y, Jiao L, Jiao Z
Acta biochimica et biophysica Sinica 2016 Aug;48(8):714-22
Acta biochimica et biophysica Sinica 2016 Aug;48(8):714-22
Endoplasmic Reticulum Stress May Play a Pivotal Role in Lipid Metabolic Disorders in a Novel Mouse Model of Subclinical Hypothyroidism.
Zhou L, Ding S, Li Y, Wang L, Chen W, Bo T, Wu K, Li C, Liu X, Zhao J, Xu C, Gao L
Scientific reports 2016 Aug 19;6:31381
Scientific reports 2016 Aug 19;6:31381
PACE4 regulates apoptosis in human prostate cancer cells via endoplasmic reticulum stress and mitochondrial signaling pathways.
Yao Z, Sun B, Hong Q, Yan J, Mu D, Li J, Sheng H, Guo H
Drug design, development and therapy 2015;9:5911-23
Drug design, development and therapy 2015;9:5911-23
Metabolic and Phenotypic Differences between Mice Producing a Werner Syndrome Helicase Mutant Protein and Wrn Null Mice.
Aumailley L, Garand C, Dubois MJ, Johnson FB, Marette A, Lebel M
PloS one 2015;10(10):e0140292
PloS one 2015;10(10):e0140292
Impaired unfolded protein response in the degeneration of cochlea cells in a mouse model of age-related hearing loss.
Wang W, Sun Y, Chen S, Zhou X, Wu X, Kong W, Kong W
Experimental gerontology 2015 Oct;70:61-70
Experimental gerontology 2015 Oct;70:61-70
IRE1 prevents endoplasmic reticulum membrane permeabilization and cell death under pathological conditions.
Kanekura K, Ma X, Murphy JT, Zhu LJ, Diwan A, Urano F
Science signaling 2015 Jun 23;8(382):ra62
Science signaling 2015 Jun 23;8(382):ra62
Polychlorinated biphenyl quinone induces endoplasmic reticulum stress, unfolded protein response, and calcium release.
Xu D, Su C, Song X, Shi Q, Fu J, Hu L, Xia X, Song E, Song Y
Chemical research in toxicology 2015 Jun 15;28(6):1326-37
Chemical research in toxicology 2015 Jun 15;28(6):1326-37
Legionella suppresses the host unfolded protein response via multiple mechanisms.
Treacy-Abarca S, Mukherjee S
Nature communications 2015 Jul 29;6:7887
Nature communications 2015 Jul 29;6:7887
Knockdown of glucose-regulated protein 78/binding immunoglobulin heavy chain protein expression by asymmetric small interfering RNA induces apoptosis in prostate cancer cells and attenuates migratory capability.
Lu T, Yang W, Wang Z, Hu Z, Zeng X, Yang C, Wang Y, Zhang Y, Li F, Liu Z, Wang D, Ye Z
Molecular medicine reports 2015 Jan;11(1):249-56
Molecular medicine reports 2015 Jan;11(1):249-56
Potent effects of the total saponins from Dioscorea nipponica Makino against streptozotocin-induced type 2 diabetes mellitus in rats.
Yu H, Zheng L, Xu L, Yin L, Lin Y, Li H, Liu K, Peng J
Phytotherapy research : PTR 2015 Feb;29(2):228-40
Phytotherapy research : PTR 2015 Feb;29(2):228-40
Impact of vitamin C on the cardiometabolic and inflammatory profiles of mice lacking a functional Werner syndrome protein helicase.
Aumailley L, Dubois MJ, Garand C, Marette A, Lebel M
Experimental gerontology 2015 Dec;72:192-203
Experimental gerontology 2015 Dec;72:192-203
Ketamine-induced ulcerative cystitis and bladder apoptosis involve oxidative stress mediated by mitochondria and the endoplasmic reticulum.
Liu KM, Chuang SM, Long CY, Lee YL, Wang CC, Lu MC, Lin RJ, Lu JH, Jang MY, Wu WJ, Ho WT, Juan YS
American journal of physiology. Renal physiology 2015 Aug 15;309(4):F318-31
American journal of physiology. Renal physiology 2015 Aug 15;309(4):F318-31
Protective effects of dioscin against alcohol-induced liver injury.
Xu T, Zheng L, Xu L, Yin L, Qi Y, Xu Y, Han X, Peng J
Archives of toxicology 2014 Mar;88(3):739-53
Archives of toxicology 2014 Mar;88(3):739-53
The resveratrol attenuates ethanol-induced hepatocyte apoptosis via inhibiting ER-related caspase-12 activation and PDE activity in vitro.
Liu LQ, Fan ZQ, Tang YF, Ke ZJ
Alcoholism, clinical and experimental research 2014 Mar;38(3):683-93
Alcoholism, clinical and experimental research 2014 Mar;38(3):683-93
Exposure to tributyltin induces endoplasmic reticulum stress and the unfolded protein response in zebrafish.
Komoike Y, Matsuoka M
Aquatic toxicology (Amsterdam, Netherlands) 2013 Oct 15;142-143:221-9
Aquatic toxicology (Amsterdam, Netherlands) 2013 Oct 15;142-143:221-9
ABCG1 deficiency promotes endothelial apoptosis by endoplasmic reticulum stress-dependent pathway.
Xue J, Wei J, Dong X, Zhu C, Li Y, Song A, Liu Z
The journal of physiological sciences : JPS 2013 Nov;63(6):435-44
The journal of physiological sciences : JPS 2013 Nov;63(6):435-44
Protein kinase RNA-like endoplasmic reticulum kinase (PERK) signaling pathway plays a major role in reactive oxygen species (ROS)-mediated endoplasmic reticulum stress-induced apoptosis in diabetic cardiomyopathy.
Liu ZW, Zhu HT, Chen KL, Dong X, Wei J, Qiu C, Xue JH
Cardiovascular diabetology 2013 Nov 2;12:158
Cardiovascular diabetology 2013 Nov 2;12:158
The alteration of protein profile induced by cigarette smoking via oxidative stress in mice epididymis.
Zhu Z, Xu W, Dai J, Chen X, Zhao X, Fang P, Yang F, Tang M, Wang Z, Wang L, Ma D, Qaio Z
The international journal of biochemistry & cell biology 2013 Mar;45(3):571-82
The international journal of biochemistry & cell biology 2013 Mar;45(3):571-82
Upregulation of phosphorylated HSP27, PRDX2, GRP75, GRP78 and GRP94 in acquired middle ear cholesteatoma growth.
Ho KY, Yeh TS, Huang HH, Hung KF, Chai CY, Chen WT, Tsai SM, Chang NC, Chien CY, Wang HM, Wu YJ
International journal of molecular sciences 2013 Jul 11;14(7):14439-59
International journal of molecular sciences 2013 Jul 11;14(7):14439-59
Protective effects of the total saponins from Rosa laevigata Michx fruit against carbon tetrachloride-induced acute liver injury in mice.
Dong D, Zhang S, Yin L, Tang X, Xu Y, Han X, Qi Y, Peng J
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2013 Dec;62:120-30
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2013 Dec;62:120-30
Selenium deficiency is associated with endoplasmic reticulum stress in a rat model of cardiac malfunction.
Wang SQ, Niu XL, Liu ZW, Zhu YH, Gao DF
Biological trace element research 2013 Dec;156(1-3):196-201
Biological trace element research 2013 Dec;156(1-3):196-201
Cell intrinsic role of COX-2 in pancreatic cancer development.
Hill R, Li Y, Tran LM, Dry S, Calvopina JH, Garcia A, Kim C, Wang Y, Donahue TR, Herschman HR, Wu H
Molecular cancer therapeutics 2012 Oct;11(10):2127-37
Molecular cancer therapeutics 2012 Oct;11(10):2127-37
Profiling of differentially expressed proteins in stage IV colorectal cancers with good and poor outcomes.
Kim HJ, Kang UB, Lee H, Jung JH, Lee ST, Yu MH, Kim H, Lee C
Journal of proteomics 2012 Jun 6;75(10):2983-97
Journal of proteomics 2012 Jun 6;75(10):2983-97
Proteomic analysis of anti-tumor effects of 11-dehydrosinulariolide on CAL-27 cells.
Liu CI, Chen CC, Chen JC, Su JH, Huang HH, Chen JY, Wu YJ
Marine drugs 2011;9(7):1254-1272
Marine drugs 2011;9(7):1254-1272
Co-chaperone HSJ1a dually regulates the proteasomal degradation of ataxin-3.
Gao XC, Zhou CJ, Zhou ZR, Zhang YH, Zheng XM, Song AX, Hu HY
PloS one 2011;6(5):e19763
PloS one 2011;6(5):e19763
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HepG2 cells were subjected to SDS PAGE followed by western blot with 11587-1-AP(GRP78,BIP antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The GRP78/BIP antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human GRP78/BIP. This antibody recognizes human, mouse, rat antigen. The GRP78/BIP antibody has been validated for the following applications: ELISA, WB, IP, IF, IHC analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-GRP78,BIP (IP:11587-1-AP, 3ug; Detection:11587-1-AP 1:1000) with MCF-7 cells lysate 3250ug.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human pancreas cancer using 11587-1-AP(GRP78,BIP antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human pancreas cancer using 11587-1-AP(GRP78,BIP antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue
