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- Antibody Data
- Antigen structure
- References [6]
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- Validations
- Immunohistochemistry [1]
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- Product number
- HPA038845 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA038845, RRID:AB_10673477
- Product name
- Anti-HSPA5
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human HSPA5, Gene description: heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa), Alternative Gene Names: BiP, GRP78, Validated applications: IHC, WB, Uniprot ID: P11021, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.1 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Regulation of Hepatitis B Virus Replication by Modulating Endoplasmic Reticulum Stress (ER‐Stress)
GRP78-CAR T cell effector function against solid and brain tumors is controlled by GRP78 expression on T cells.
ER-stress promotes VHL-independent degradation of hypoxia-inducible factors via FBXW1A/βTrCP
The Clinicopathological Significance of BiP/GRP-78 in Breast Cancer: A Meta-Analysis of Public Datasets and Immunohistochemical Detection
Gene expression and in situ protein profiling of candidate SARS-CoV-2 receptors in human airway epithelial cells and lung tissue.
Translocation of molecular chaperones to the titin springs is common in skeletal myopathy patients and affects sarcomere function
Hossain M, Ueda K, Zhang Y
International Journal of Microbiology 2024;2024(1)
International Journal of Microbiology 2024;2024(1)
GRP78-CAR T cell effector function against solid and brain tumors is controlled by GRP78 expression on T cells.
Ibanez J, Hebbar N, Thanekar U, Yi Z, Houke H, Ward M, Nevitt C, Tian L, Mack SC, Sheppard H, Chiang J, Velasquez MP, Krenciute G
Cell reports. Medicine 2023 Nov 21;4(11):101297
Cell reports. Medicine 2023 Nov 21;4(11):101297
ER-stress promotes VHL-independent degradation of hypoxia-inducible factors via FBXW1A/βTrCP
Mennerich D, Kubaichuk K, Raza G, Fuhrmann D, Herzig K, Brüne B, Kietzmann T
Redox Biology 2022;50
Redox Biology 2022;50
The Clinicopathological Significance of BiP/GRP-78 in Breast Cancer: A Meta-Analysis of Public Datasets and Immunohistochemical Detection
Direito I, Gomes D, Monteiro F, Carneiro I, Lobo J, Henrique R, Jerónimo C, Helguero L
Current Oncology 2022;29(12):9066-9087
Current Oncology 2022;29(12):9066-9087
Gene expression and in situ protein profiling of candidate SARS-CoV-2 receptors in human airway epithelial cells and lung tissue.
Aguiar JA, Tremblay BJ, Mansfield MJ, Woody O, Lobb B, Banerjee A, Chandiramohan A, Tiessen N, Cao Q, Dvorkin-Gheva A, Revill S, Miller MS, Carlsten C, Organ L, Joseph C, John A, Hanson P, Austin RC, McManus BM, Jenkins G, Mossman K, Ask K, Doxey AC, Hirota JA
The European respiratory journal 2020 Sep;56(3)
The European respiratory journal 2020 Sep;56(3)
Translocation of molecular chaperones to the titin springs is common in skeletal myopathy patients and affects sarcomere function
Unger A, Beckendorf L, Böhme P, Kley R, von Frieling-Salewsky M, Lochmüller H, Schröder R, Fürst D, Vorgerd M, Linke W
Acta Neuropathologica Communications 2017;5(1)
Acta Neuropathologica Communications 2017;5(1)
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human placenta and skeletal muscle tissues using HPA038845 antibody. Corresponding HSPA5 RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol
