Antibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations [0]
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- Product number
- GMA-8022 - Provider product page
- Provider
- Green Mountain Antibodies
- Product name
- Anti-Factor VIII
- Antibody type
- Monoclonal
- Antigen
- Factor VIII
- Description
- GMA-8022 is a C2 domain specific antibody useful for detection of Factor VIII by ELISA. Binding is unaffected by von Willebrand factor and phospholipid. It has been shown to inhibit the activation of Factor VIII by either thrombin or factor Xa (type II inhibitor)1. GMA-8022 is the designated cell line I14 as described by Meeks, S et al. in reference 1.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- GMA-8022
- Vial size
- 0.1mg, 0.5mg
Submitted references Antihuman factor VIII C2 domain antibodies in hemophilia A mice recognize a functionally complex continuous spectrum of epitopes dominated by inhibitors of factor VIII activation.
Meeks SL, Healey JF, Parker ET, Barrow RT, Lollar P
Blood 2007 Dec 15;110(13):4234-42
Blood 2007 Dec 15;110(13):4234-42
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