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LearnABIN1881807
antibody from antibodies-online
Targeting: PTPN11
BPTP3, NS1, PTP2C, SH-PTP2, SHP-2, SHP2
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
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- Validations
- Western blot [2]
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- Product number
- ABIN1881807 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) (pTyr584) antibody
- Antibody type
- Polyclonal
- Antigen
- This SHP2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y584 of human SHP2.
- Description
- This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- pTyr584
- Antibody clone number
- RB16677
- Vial size
- 400 μL
- Concentration
- 0.5 mg/mL
Submitted references Mitochondrial DNA haplogroup 'R' is associated with Noonan syndrome of south India.
Prolactin enhances insulin-like growth factor I receptor phosphorylation by decreasing its association with the tyrosine phosphatase SHP-2 in MCF-7 breast cancer cells.
The phosphatase Shp2 is required for signaling by the Kaposi's sarcoma-associated herpesvirus viral GPCR in primary endothelial cells.
Rani DS, Dhandapany PS, Nallari P, Govindaraj P, Singh L, Thangaraj K
Mitochondrion 2010 Mar;10(2):166-73
Mitochondrion 2010 Mar;10(2):166-73
Prolactin enhances insulin-like growth factor I receptor phosphorylation by decreasing its association with the tyrosine phosphatase SHP-2 in MCF-7 breast cancer cells.
Carver KC, Piazza TM, Schuler LA
The Journal of biological chemistry 2010 Mar 12;285(11):8003-12
The Journal of biological chemistry 2010 Mar 12;285(11):8003-12
The phosphatase Shp2 is required for signaling by the Kaposi's sarcoma-associated herpesvirus viral GPCR in primary endothelial cells.
Bakken T, He M, Cannon ML
Virology 2010 Feb 20;397(2):379-88
Virology 2010 Feb 20;397(2):379-88
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Dot blot analysis of anti-Phospho-SHP2-pY584 Phospho-specific Pab (ABIN1881807) on nitrocellulose membrane. 50 ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5 μg per mL.
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Dot blot analysis of anti-Phospho-SHP2-pY584 Phospho-specific Pab (ABIN1881807) on nitrocellulose membrane. 50 ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5 μg per mL.
