ABIN363040

antibody from antibodies-online

Targeting: PTPN11 BPTP3, NS1, PTP2C, SH-PTP2, SHP-2, SHP2

Western blot (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN363040

Provider

antibodies-online

Product name

anti-Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) (AA 578-582) antibody

Antibody type

Polyclonal

Antigen

Peptide sequence around AA 578-582 (R-V-Y-E-N) derived from Human SHP-2. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Epitope

AA 578-582

Isotype

IgG

Vial size

100 μL

Concentration

1 mg/mL

Storage

Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

References

Submitted references

Critical role of Src and SHP-2 in sst2 somatostatin receptor-mediated activation of SHP-1 and inhibition of cell proliferation.

Ferjoux G, Lopez F, Esteve JP, Ferrand A, Vivier E, Vely F, Saint-Laurent N, Pradayrol L, Buscail L, Susini C
Molecular biology of the cell 2003 Sep;14(9):3911-28

---

Molecular mechanism for the Shp-2 tyrosine phosphatase function in promoting growth factor stimulation of Erk activity.

Shi ZQ, Yu DH, Park M, Marshall M, Feng GS
Molecular and cellular biology 2000 Mar;20(5):1526-36