ABIN968068

antibody from antibodies-online

Targeting: PTPN11 BPTP3, NS1, PTP2C, SH-PTP2, SHP-2, SHP2

Western blot (Recommended by provider)

Immunocytochemistry (Data presented on provider website)

Immunoprecipitation (Recommended by provider)

Antibody Data

Product number

ABIN968068

Provider

antibodies-online

Product name

anti-Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) (AA 1-177) antibody

Antibody type

Monoclonal

Antigen

Human PTP1D (SHP2)

Description

Purified from tissue culture supernatant or ascites by affinity chromatography.

Reactivity

Human

Host

Mouse

Epitope

AA 1-177

Isotype

IgG

Antibody clone number

MB3

Vial size

50 μg

Concentration

250 μg/ml

Storage

-20°C

References

Submitted references

A novel protein-protein interaction between a G protein-coupled receptor and the phosphatase SHP-2 is involved in bradykinin-induced inhibition of cell proliferation.

Duchene J, Schanstra JP, Pecher C, Pizard A, Susini C, Esteve JP, Bascands JL, Girolami JP
The Journal of biological chemistry 2002 Oct 25;277(43):40375-83

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Role of SHP-2 in fibroblast growth factor receptor-mediated suppression of myogenesis in C2C12 myoblasts.

Kontaridis MI, Liu X, Zhang L, Bennett AM
Molecular and cellular biology 2002 Jun;22(11):3875-91

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Role that each NKG2A immunoreceptor tyrosine-based inhibitory motif plays in mediating the human CD94/NKG2A inhibitory signal.

Kabat J, Borrego F, Brooks A, Coligan JE
Journal of immunology (Baltimore, Md. : 1950) 2002 Aug 15;169(4):1948-58

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Activation of a phosphotyrosine phosphatase by tyrosine phosphorylation.

Vogel W, Lammers R, Huang J, Ullrich A
Science (New York, N.Y.) 1993 Mar 12;259(5101):1611-4

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Identification of a human src homology 2-containing protein-tyrosine-phosphatase: a putative homolog of Drosophila corkscrew.

Freeman RM Jr, Plutzky J, Neel BG
Proceedings of the National Academy of Sciences of the United States of America 1992 Dec 1;89(23):11239-43