Antibody data
- Antibody Data
- Antigen structure
- References [26]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 10429-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10429-1-AP, RRID:AB_2247334
- Product name
- SMAD1 antibody
- Antibody type
- Polyclonal
- Description
- SMAD1 antibody (Cat. #10429-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IP, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Lrg1 silencing attenuates ischemia-reperfusion renal injury by regulating autophagy and apoptosis through the TGFβ1- Smad1/5 signaling pathway.
Regulation of the immune microenvironment by pioglitazone-loaded polylactic glycolic acid nanosphere composite scaffolds to promote vascularization and bone regeneration.
Nicotinamide adenine dinucleotide kinase promotes lymph node metastasis of NSCLC via activating ID1 expression through BMP pathway.
Chronic intermittent hypobaric hypoxia improves iron metabolism disorders via the IL-6/JAK2/STAT3 and Epo/STAT5/ERFE signaling pathways in metabolic syndrome rats.
Bioprinted constructs that simulate nerve-bone crosstalk to improve microenvironment for bone repair.
A negative feedback loop centered on SMAD3 expression in transforming growth factor β1-induced corneal myofibroblast differentiation.
The chromatin remodeling protein BRG1 regulates HSC-myofibroblast differentiation and liver fibrosis.
Tax1 binding protein 3 regulates osteogenic and adipogenic differentiation through inactivating Wnt/β-catenin signalling.
Atorvastatin Inhibits Ferroptosis of H9C2 Cells by regulatingSMAD7/Hepcidin Expression to Improve Ischemia-Reperfusion Injury.
BMP-7 ameliorates partial epithelial-mesenchymal transition by restoring SnoN protein level via Smad1/5 pathway in diabetic kidney disease.
miR-122-5p targets GREM2 to protect against glucocorticoid-induced endothelial damage through the BMP signaling pathway.
Expression of GALNT8 and O-glycosylation of BMP receptor 1A suppress breast cancer cell proliferation by upregulating ERα levels.
In vitro and in silico anti-osteoporosis activities and underlying mechanisms of a fructan, ABW90-1, from Achyranthes bidentate.
TAZ promotes osteogenic differentiation of mesenchymal stem cells line C3H10T1/2, murine multi-lineage cells lines C2C12, and MEFs induced by BMP9.
Guizhi Fuling pill attenuates liver fibrosis in vitro and in vivo via inhibiting TGF-β1/Smad2/3 and activating IFN-γ/Smad7 signaling pathways.
Schisandrin B regulates MC3T3-E1 subclone 14 cells proliferation and differentiation through BMP2-SMADs-RUNX2-SP7 signaling axis.
Aspirin promotes tenogenic differentiation of tendon stem cells and facilitates tendinopathy healing through regulating the GDF7/Smad1/5 signaling pathway.
Osteoporosis genome-wide association study variant c.3781 C>A is regulated by a novel anti-osteogenic factor miR-345-5p.
Exosomal miR-125a-5p derived from silica-exposed macrophages induces fibroblast transdifferentiation.
ZnO nanoparticles inhibit the activity of Porphyromonas gingivalis and Actinomyces naeslundii and promote the mineralization of the cementum.
Mmu-miR-185 depletion promotes osteogenic differentiation and suppresses bone loss in osteoporosis through the Bgn-mediated BMP/Smad pathway.
LRG1 Promotes Apoptosis and Autophagy through the TGFβ-smad1/5 Signaling Pathway to Exacerbate Ischemia/Reperfusion Injury.
Silencing SOCS3 Markedly Deteriorates Spondyloarthritis in Mice Induced by Minicircle DNA Expressing IL23.
Abnormal expression levels of BMP15/Smad1 are associated with granulosa cell apoptosis in patients with polycystic ovary syndrome.
Tcf4 Controls Neuronal Migration of the Cerebral Cortex through Regulation of Bmp7.
IL-27 alleviates the bleomycin-induced pulmonary fibrosis by regulating the Th17 cell differentiation.
Chen J, Zhang Z, Feng L, Liu W, Wang X, Chen H, Zou H
Archives of biochemistry and biophysics 2024 Mar;753:109892
Archives of biochemistry and biophysics 2024 Mar;753:109892
Regulation of the immune microenvironment by pioglitazone-loaded polylactic glycolic acid nanosphere composite scaffolds to promote vascularization and bone regeneration.
Fan S, Tan Y, Yuan X, Liu C, Wu X, Dai T, Ni S, Wang J, Weng Y, Zhao H
Journal of tissue engineering 2024 Jan-Dec;15:20417314241231452
Journal of tissue engineering 2024 Jan-Dec;15:20417314241231452
Nicotinamide adenine dinucleotide kinase promotes lymph node metastasis of NSCLC via activating ID1 expression through BMP pathway.
Zeng Z, Gao J, Chen T, Zhang Z, Li M, Fan Q, Liu G, Li X, Li Z, Zhong C, Yao F, Sun L, Deng Y, Li M
International journal of biological sciences 2023;19(10):3184-3199
International journal of biological sciences 2023;19(10):3184-3199
Chronic intermittent hypobaric hypoxia improves iron metabolism disorders via the IL-6/JAK2/STAT3 and Epo/STAT5/ERFE signaling pathways in metabolic syndrome rats.
Cui F, Sun J, Mi H, Li B, Tang L, Wang R, Du Y, Guo B, Li Y, Shi M
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2023 Sep;79:127259
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2023 Sep;79:127259
Bioprinted constructs that simulate nerve-bone crosstalk to improve microenvironment for bone repair.
Wang T, Li W, Zhang Y, Xu X, Qiang L, Miao W, Yue X, Jiao X, Zhou X, Ma Z, Li S, Ding M, Zhu J, Yang C, Wang H, Li T, Sun X, Wang J
Bioactive materials 2023 Sep;27:377-393
Bioactive materials 2023 Sep;27:377-393
A negative feedback loop centered on SMAD3 expression in transforming growth factor β1-induced corneal myofibroblast differentiation.
Tang Y, Du E, Wang G, Qin F, Meng Z, Dai L, Wang Y, Ren S
Experimental eye research 2023 Nov;236:109654
Experimental eye research 2023 Nov;236:109654
The chromatin remodeling protein BRG1 regulates HSC-myofibroblast differentiation and liver fibrosis.
Zhu Y, Kang A, Kuai Y, Guo Y, Miao X, Zhu L, Kong M, Li N
Cell death & disease 2023 Dec 14;14(12):826
Cell death & disease 2023 Dec 14;14(12):826
Tax1 binding protein 3 regulates osteogenic and adipogenic differentiation through inactivating Wnt/β-catenin signalling.
Wang Y, Gan Y, Dong Y, Zhou J, Zhu E, Yuan H, Li X, Wang B
Journal of cellular and molecular medicine 2023 Apr;27(7):950-961
Journal of cellular and molecular medicine 2023 Apr;27(7):950-961
Atorvastatin Inhibits Ferroptosis of H9C2 Cells by regulatingSMAD7/Hepcidin Expression to Improve Ischemia-Reperfusion Injury.
Peng Y, Liao B, Zhou Y, Zeng W, Zeng ZY
Cardiology research and practice 2022;2022:3972829
Cardiology research and practice 2022;2022:3972829
BMP-7 ameliorates partial epithelial-mesenchymal transition by restoring SnoN protein level via Smad1/5 pathway in diabetic kidney disease.
Peng W, Zhou X, Xu T, Mao Y, Zhang X, Liu H, Liang L, Liu L, Liu L, Xiao Y, Zhang F, Li S, Shi M, Zhou Y, Tang L, Wang Y, Guo B
Cell death & disease 2022 Mar 21;13(3):254
Cell death & disease 2022 Mar 21;13(3):254
miR-122-5p targets GREM2 to protect against glucocorticoid-induced endothelial damage through the BMP signaling pathway.
Huang X, Jie S, Li W, Li H, Ni J, Liu C
Molecular and cellular endocrinology 2022 Mar 15;544:111541
Molecular and cellular endocrinology 2022 Mar 15;544:111541
Expression of GALNT8 and O-glycosylation of BMP receptor 1A suppress breast cancer cell proliferation by upregulating ERα levels.
Huang T, Wu Q, Huang H, Zhang C, Wang L, Wang L, Liu Y, Li W, Zhang J, Liu Y
Biochimica et biophysica acta. General subjects 2022 Jan;1866(1):130046
Biochimica et biophysica acta. General subjects 2022 Jan;1866(1):130046
In vitro and in silico anti-osteoporosis activities and underlying mechanisms of a fructan, ABW90-1, from Achyranthes bidentate.
Li T, Hou X, Huang Y, Wang C, Chen H, Yan C
Carbohydrate polymers 2022 Jan 15;276:118730
Carbohydrate polymers 2022 Jan 15;276:118730
TAZ promotes osteogenic differentiation of mesenchymal stem cells line C3H10T1/2, murine multi-lineage cells lines C2C12, and MEFs induced by BMP9.
Huang H, Lu Q, Ye C, Wei M, Yang C, Zhang L, Huang Y, Luo X, Luo J
Cell death discovery 2022 Dec 27;8(1):499
Cell death discovery 2022 Dec 27;8(1):499
Guizhi Fuling pill attenuates liver fibrosis in vitro and in vivo via inhibiting TGF-β1/Smad2/3 and activating IFN-γ/Smad7 signaling pathways.
Liu Z, Xu B, Ding Y, Ding X, Yang Z
Bioengineered 2022 Apr;13(4):9357-9368
Bioengineered 2022 Apr;13(4):9357-9368
Schisandrin B regulates MC3T3-E1 subclone 14 cells proliferation and differentiation through BMP2-SMADs-RUNX2-SP7 signaling axis.
Wang X, Liao X, Zhang Y, Wei L, Pang Y
Scientific reports 2020 Sep 2;10(1):14476
Scientific reports 2020 Sep 2;10(1):14476
Aspirin promotes tenogenic differentiation of tendon stem cells and facilitates tendinopathy healing through regulating the GDF7/Smad1/5 signaling pathway.
Wang Y, He G, Tang H, Shi Y, Zhu M, Kang X, Bian X, Lyu J, Zhou M, Yang M, Mu M, Chen W, Zhou B, Yuan C, Zhang J, Tang K
Journal of cellular physiology 2020 May;235(5):4778-4789
Journal of cellular physiology 2020 May;235(5):4778-4789
Osteoporosis genome-wide association study variant c.3781 C>A is regulated by a novel anti-osteogenic factor miR-345-5p.
Wang Y, Ye W, Liu Y, Mei B, Liu X, Huang Q
Human mutation 2020 Mar;41(3):709-718
Human mutation 2020 Mar;41(3):709-718
Exosomal miR-125a-5p derived from silica-exposed macrophages induces fibroblast transdifferentiation.
Wang D, Hao C, Zhang L, Zhang J, Liu S, Li Y, Qu Y, Zhao Y, Huang R, Wei J, Yao W
Ecotoxicology and environmental safety 2020 Apr 1;192:110253
Ecotoxicology and environmental safety 2020 Apr 1;192:110253
ZnO nanoparticles inhibit the activity of Porphyromonas gingivalis and Actinomyces naeslundii and promote the mineralization of the cementum.
Wang J, Du L, Fu Y, Jiang P, Wang X
BMC oral health 2019 May 14;19(1):84
BMC oral health 2019 May 14;19(1):84
Mmu-miR-185 depletion promotes osteogenic differentiation and suppresses bone loss in osteoporosis through the Bgn-mediated BMP/Smad pathway.
Cui Q, Xing J, Yu M, Wang Y, Xu J, Gu Y, Nan X, Ma W, Liu H, Zhao H
Cell death & disease 2019 Feb 20;10(3):172
Cell death & disease 2019 Feb 20;10(3):172
LRG1 Promotes Apoptosis and Autophagy through the TGFβ-smad1/5 Signaling Pathway to Exacerbate Ischemia/Reperfusion Injury.
Jin J, Sun H, Liu D, Wang H, Liu Q, Chen H, Zhong D, Li G
Neuroscience 2019 Aug 10;413:123-134
Neuroscience 2019 Aug 10;413:123-134
Silencing SOCS3 Markedly Deteriorates Spondyloarthritis in Mice Induced by Minicircle DNA Expressing IL23.
Chen Y, Ouyang J, Yan R, Maarouf MH, Wang X, Chen B, Liu S, Hu J, Guo G, Zhang J, Dai SM, Xu H, Chen JL
Frontiers in immunology 2018;9:2641
Frontiers in immunology 2018;9:2641
Abnormal expression levels of BMP15/Smad1 are associated with granulosa cell apoptosis in patients with polycystic ovary syndrome.
Cui X, Jing X, Wu X, Bi X, Liu J, Long Z, Zhang X, Zhang D, Jia H, Su D, Huo K
Molecular medicine reports 2017 Dec;16(6):8231-8236
Molecular medicine reports 2017 Dec;16(6):8231-8236
Tcf4 Controls Neuronal Migration of the Cerebral Cortex through Regulation of Bmp7.
Chen T, Wu Q, Zhang Y, Lu T, Yue W, Zhang D
Frontiers in molecular neuroscience 2016;9:94
Frontiers in molecular neuroscience 2016;9:94
IL-27 alleviates the bleomycin-induced pulmonary fibrosis by regulating the Th17 cell differentiation.
Dong Z, Lu X, Yang Y, Zhang T, Li Y, Chai Y, Lei W, Li C, Ai L, Tai W
BMC pulmonary medicine 2015 Feb 18;15:13
BMC pulmonary medicine 2015 Feb 18;15:13
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The SMAD1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human SMAD1. This antibody recognizes human, mouse, rat antigen. The SMAD1 antibody has been validated for the following applications: ELISA, WB analysis.