Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- MAB822 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal XIAP Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects human and mouse XIAP in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) cIAP-1 or rhcIAP-2 is observed.
- Reactivity
- Human, Mouse
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Submitted references Inhibitor of apoptosis proteins are required for effective fusion of autophagosomes with lysosomes.
Evaluating the Mechanism and Therapeutic Potential of PTC-028, a Novel Inhibitor of BMI-1 Function in Ovarian Cancer.
Protein kinase C ζ regulates survivin expression and inhibits apoptosis in colon cancer.
MUC16 mucin (CA125) attenuates TRAIL-induced apoptosis by decreasing TRAIL receptor R2 expression and increasing c-FLIP expression.
Axonal degeneration is regulated by the apoptotic machinery or a NAD+-sensitive pathway in insects and mammals.
Gradzka S, Thomas OS, Kretz O, Haimovici A, Vasilikos L, Wong WW, Häcker G, Gentle IE
Cell death & disease 2018 May 1;9(5):529
Cell death & disease 2018 May 1;9(5):529
Evaluating the Mechanism and Therapeutic Potential of PTC-028, a Novel Inhibitor of BMI-1 Function in Ovarian Cancer.
Dey A, Xiong X, Crim A, Dwivedi SKD, Mustafi SB, Mukherjee P, Cao L, Sydorenko N, Baiazitov R, Moon YC, Dumble M, Davis T, Bhattacharya R
Molecular cancer therapeutics 2018 Jan;17(1):39-49
Molecular cancer therapeutics 2018 Jan;17(1):39-49
Protein kinase C ζ regulates survivin expression and inhibits apoptosis in colon cancer.
Umemori Y, Kuribayashi K, Nirasawa S, Kondoh T, Tanaka M, Kobayashi D, Watanabe N
International journal of oncology 2014 Sep;45(3):1043-50
International journal of oncology 2014 Sep;45(3):1043-50
MUC16 mucin (CA125) attenuates TRAIL-induced apoptosis by decreasing TRAIL receptor R2 expression and increasing c-FLIP expression.
Matte I, Lane D, Boivin M, Rancourt C, Piché A
BMC cancer 2014 Apr 1;14:234
BMC cancer 2014 Apr 1;14:234
Axonal degeneration is regulated by the apoptotic machinery or a NAD+-sensitive pathway in insects and mammals.
Schoenmann Z, Assa-Kunik E, Tiomny S, Minis A, Haklai-Topper L, Arama E, Yaron A
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010 May 5;30(18):6375-86
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010 May 5;30(18):6375-86
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Detection of Human/Mouse XIAP by Western Blot. Detection of Human/Mouse XIAP by Western Blot.