XIAP

gene product
API3, BIRC4, hILP
This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11. [provided by RefSeq, Feb 2011]
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Antibodies

 

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Antibodypedia Validation Initiative

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Conjugate

  or   Clear
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Eligible for validation within AVI
638 antibodies from 39 providers.

Antibody properties

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AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
18 antibodies
antibodies-online
239 antibodies
Enzo Life Sciences
2 antibodies
GeneTex
7 antibodies
R&D Systems
4 antibodies
Proteintech Group
2 antibodies
Abnova Corporation
14 antibodies
OriGene
13 antibodies
Acris Antibodies GmbH
22 antibodies
NovoPro Bioscience Inc.
3 antibodies
Invitrogen Antibodies
12 antibodies
Cell Signaling Technology, Inc
3 antibodies
Biorbyt
36 antibodies
LifeSpan BioSciences, Inc.
109 antibodies
SignalChem
1 antibody
St John's Laboratory
7 antibodies
Affinity Biosciences
2 antibodies
Abgent
6 antibodies
Boster Biological Technology
3 antibodies
ProSci
3 antibodies
NSJ Bioreagents
3 antibodies
Santa Cruz Biotechnology
1 antibody
Bioworld Technology, Inc
1 antibody
Abbexa
4 antibodies
Aviva Systems Biology
4 antibodies
Abbkine Scientific Co.Ltd.
2 antibodies
RabMAbs
3 antibodies
MyBioSource
10 antibodies
RayBiotech, Inc.
9 antibodies
Abbiotec
1 antibody
Arigo
1 antibody
Atlas Antibodies
1 antibody
United States Biological
80 antibodies
Creative Diagnostics
3 antibodies
GenWay
3 antibodies
Sigma-Aldrich
3 antibodies
eBioscience, An Affymetrix Company
1 antibody
EMD Millipore
1 antibody
Rockland Immunochemicals, Inc.
1 antibody