Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Immunocytochemistry [1]
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Validation data
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- Product number
- ADI-AAM-050-E - Provider product page
- Provider
- Enzo Life Sciences
- Proper citation
- Enzo Life Sciences Cat#ADI-AAM-050-E, RRID:AB_2039687
- Product name
- XIAP monoclonal antibody (2F1)
- Antibody type
- Monoclonal
- Antigen
- Recombinant full length protein
- Description
- Protein A affinity purified.
- Reactivity
- Human, Mouse
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 2F1
- Vial size
- 100 μg
- Storage
- -20°C
Submitted references Silibinin sensitizes human glioma cells to TRAIL-mediated apoptosis via DR5 up-regulation and down-regulation of c-FLIP and survivin.
Interaction between XIAP and Smac/DIABLO in the mouse brain after transient focal cerebral ischemia.
Role of Smac in human leukaemic cell apoptosis and proliferation.
XIAP, a cellular member of the inhibitor of apoptosis protein family, links the receptors to TAB1-TAK1 in the BMP signaling pathway.
Son YG, Kim EH, Kim JY, Kim SU, Kwon TK, Yoon AR, Yun CO, Choi KS
Cancer research 2007 Sep 1;67(17):8274-84
Cancer research 2007 Sep 1;67(17):8274-84
Interaction between XIAP and Smac/DIABLO in the mouse brain after transient focal cerebral ischemia.
Saito A, Hayashi T, Okuno S, Ferrand-Drake M, Chan PH
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2003 Sep;23(9):1010-9
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2003 Sep;23(9):1010-9
Role of Smac in human leukaemic cell apoptosis and proliferation.
Jia L, Patwari Y, Kelsey SM, Srinivasula SM, Agrawal SG, Alnemri ES, Newland AC
Oncogene 2003 Mar 20;22(11):1589-99
Oncogene 2003 Mar 20;22(11):1589-99
XIAP, a cellular member of the inhibitor of apoptosis protein family, links the receptors to TAB1-TAK1 in the BMP signaling pathway.
Yamaguchi K, Nagai S, Ninomiya-Tsuji J, Nishita M, Tamai K, Irie K, Ueno N, Nishida E, Shibuya H, Matsumoto K
The EMBO journal 1999 Jan 4;18(1):179-87
The EMBO journal 1999 Jan 4;18(1):179-87
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Supportive validation
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- Enzo Life Sciences (provider)
- Main image
- Experimental details
- Western blot analysis of Jurkat (1), Raji (2), HeLa (3), WR19L (4) and PC12 (5) cells, probed with XIAP mAb (2F1).