Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
Reference
Comment
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- Product number
- PAB12923 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB12923, RRID:AB_10676606
- Product name
- XIAP polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of XIAP.
- Storage
- Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Translational upregulation of X-linked inhibitor of apoptosis (XIAP) increases resistance to radiation induced cell death.
Cleavage of human inhibitor of apoptosis protein XIAP results in fragments with distinct specificities for caspases.
X-linked IAP is a direct inhibitor of cell-death proteases.
Holcik M, Yeh C, Korneluk RG, Chow T
Oncogene 2000 Aug 24;19(36):4174-7
Oncogene 2000 Aug 24;19(36):4174-7
Cleavage of human inhibitor of apoptosis protein XIAP results in fragments with distinct specificities for caspases.
Deveraux QL, Leo E, Stennicke HR, Welsh K, Salvesen GS, Reed JC
The EMBO journal 1999 Oct 1;18(19):5242-51
The EMBO journal 1999 Oct 1;18(19):5242-51
X-linked IAP is a direct inhibitor of cell-death proteases.
Deveraux QL, Takahashi R, Salvesen GS, Reed JC
Nature 1997 Jul 17;388(6639):300-4
Nature 1997 Jul 17;388(6639):300-4
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of XIAP in human kidney lysate with XIAP polyclonal antibody (Cat # PAB12923) at 0.5 (lane A), 1 (lane B), and 2 (lane C) ug/mL , respectively.
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Immunohistochemical staining of human kidney tissue using XIAP polyclonal antibody (Cat # PAB12923) at 2 ug/mL .
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)