Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [3]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- GTX111202 - Provider product page
- Provider
- GeneTex
- Proper citation
- GeneTex Cat#GTX111202, RRID:AB_10614971
- Product name
- XIAP antibody
- Antibody type
- Polyclonal
- Reactivity
- Human, Mouse
- Host
- Rabbit
Submitted references Pharmacological targeting of HSP90 with 17-AAG induces apoptosis of myogenic cells through activation of the intrinsic pathway.
SP110b Controls Host Immunity and Susceptibility to Tuberculosis.
Targeting the XIAP/caspase-7 complex selectively kills caspase-3-deficient malignancies.
Wagatsuma A, Takayama Y, Hoshino T, Shiozuka M, Yamada S, Matsuda R, Mabuchi K
Molecular and cellular biochemistry 2018 Aug;445(1-2):45-58
Molecular and cellular biochemistry 2018 Aug;445(1-2):45-58
SP110b Controls Host Immunity and Susceptibility to Tuberculosis.
Leu JS, Chen ML, Chang SY, Yu SL, Lin CW, Wang H, Chen WC, Chang CH, Wang JY, Lee LN, Yu CJ, Kramnik I, Yan BS
American journal of respiratory and critical care medicine 2017 Feb 1;195(3):369-382
American journal of respiratory and critical care medicine 2017 Feb 1;195(3):369-382
Targeting the XIAP/caspase-7 complex selectively kills caspase-3-deficient malignancies.
Lin YF, Lai TC, Chang CK, Chen CL, Huang MS, Yang CJ, Liu HG, Dong JJ, Chou YA, Teng KH, Chen SH, Tian WT, Jan YH, Hsiao M, Liang PH
The Journal of clinical investigation 2013 Sep;123(9):3861-75
The Journal of clinical investigation 2013 Sep;123(9):3861-75
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Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Sample (50 ug of whole cell lysate) A: Mouse brain 7.5% SDS PAGE GTX111202 diluted at 1:1000
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Wild-type (WT) and XIAP knockout (KO) HeLa cell extracts (30 ?g) were separated by 7.5% SDS-PAGE, and the membrane was blotted with XIAP antibody (GTX111202) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Wild-type (WT) and XIAP knockout (KO) HeLa cell extracts (30 ?g) were separated by 7.5% SDS-PAGE, and the membrane was blotted with XIAP antibody (GTX111202) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Immunofluorescence analysis of methanol-fixed HeLa, using XIAP(GTX111202) antibody at 1:500 dilution.
Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of paraffin-embedded Hs578T xenograft, using XIAP(GTX111202) antibody at 1:500 dilution.