PABPC5

This gene encodes a protein that binds to the polyA tail found at the 3' end of most eukaryotic mRNAs. It is thought to play a role in the regulation of mRNA metabolic processes in the cytoplasm. This gene is located in a gene-poor region within the X-specific 13d-sY43 subinterval of the chromosome Xq21.3/Yp11.2 homology block. It is located close to translocation breakpoints associated with premature ovarian failure, and is therefore a potential candidate gene for this disorder. [provided by RefSeq, May 2010]

Description

Poly(A) binding protein cytoplasmic 5

Tissue specificity

Tissue enhanced (adrenal gland, ovary)

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins

Chromosome

X (91434595 - 91438584)

Ensembl ID

ENSG00000174740  (ver. 103.38)

Orthologs

Mouse Pabpc5: ENSMUSG00000034732

UniProt

Q96DU9

neXtProt

NX_Q96DU9

Human splice variants
Mouse splice variants

Protein structure