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- References [12]
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- Product number
- ABIN2844092 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) (AA 457-486) antibody
- Antibody type
- Polyclonal
- Description
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- AA 457-486
- Antibody clone number
- RB01852
- Vial size
- 80 μL
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Submitted references Glucocorticoid-induced S-adenosylmethionine enhances the interferon signaling pathway by restoring STAT1 protein methylation in hepatitis B virus-infected cells.
Hiwi mediated tumorigenesis is associated with DNA hypermethylation.
OxLDL up-regulates microRNA-29b, leading to epigenetic modifications of MMP-2/MMP-9 genes: a novel mechanism for cardiovascular diseases.
Sex-specific radiation-induced microRNAome responses in the hippocampus, cerebellum and frontal cortex in a mouse model.
DNA methyltransferase expression in the human endometrium: down-regulation by progesterone and estrogen.
Up-regulation of DNA-methyltransferase 3A expression is associated with hypomethylation of intron 25 in human testicular germ cell tumors.
Role of epigenetic effectors in maintenance of the long-term persistent bystander effect in spleen in vivo.
Irradiation induces DNA damage and modulates epigenetic effectors in distant bystander tissue in vivo.
Effect of long-term tamoxifen exposure on genotoxic and epigenetic changes in rat liver: implications for tamoxifen-induced hepatocarcinogenesis.
Fractionated low-dose radiation exposure leads to accumulation of DNA damage and profound alterations in DNA and histone methylation in the murine thymus.
The human DNA methyltransferases (DNMTs) 1, 3a and 3b: coordinate mRNA expression in normal tissues and overexpression in tumors.
Cloning, expression and chromosome locations of the human DNMT3 gene family.
Bing Y, Zhu S, Yu G, Li T, Liu W, Li C, Wang Y, Qi H, Guo T, Yuan Y, He Y, Liu Z, Liu Q
The Journal of biological chemistry 2014 Nov 21;289(47):32639-55
The Journal of biological chemistry 2014 Nov 21;289(47):32639-55
Hiwi mediated tumorigenesis is associated with DNA hypermethylation.
Siddiqi S, Terry M, Matushansky I
PloS one 2012;7(3):e33711
PloS one 2012;7(3):e33711
OxLDL up-regulates microRNA-29b, leading to epigenetic modifications of MMP-2/MMP-9 genes: a novel mechanism for cardiovascular diseases.
Chen KC, Wang YS, Hu CY, Chang WC, Liao YC, Dai CY, Juo SH
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2011 May;25(5):1718-28
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2011 May;25(5):1718-28
Sex-specific radiation-induced microRNAome responses in the hippocampus, cerebellum and frontal cortex in a mouse model.
Koturbash I, Zemp F, Kolb B, Kovalchuk O
Mutation research 2011 Jun 17;722(2):114-8
Mutation research 2011 Jun 17;722(2):114-8
DNA methyltransferase expression in the human endometrium: down-regulation by progesterone and estrogen.
Yamagata Y, Asada H, Tamura I, Lee L, Maekawa R, Taniguchi K, Taketani T, Matsuoka A, Tamura H, Sugino N
Human reproduction (Oxford, England) 2009 May;24(5):1126-32
Human reproduction (Oxford, England) 2009 May;24(5):1126-32
Up-regulation of DNA-methyltransferase 3A expression is associated with hypomethylation of intron 25 in human testicular germ cell tumors.
Ishii T, Kohu K, Yamada S, Ishidoya S, Kanto S, Fuji H, Moriya T, Satake M, Arai Y
The Tohoku journal of experimental medicine 2007 Jun;212(2):177-90
The Tohoku journal of experimental medicine 2007 Jun;212(2):177-90
Role of epigenetic effectors in maintenance of the long-term persistent bystander effect in spleen in vivo.
Koturbash I, Boyko A, Rodriguez-Juarez R, McDonald RJ, Tryndyak VP, Kovalchuk I, Pogribny IP, Kovalchuk O
Carcinogenesis 2007 Aug;28(8):1831-8
Carcinogenesis 2007 Aug;28(8):1831-8
Irradiation induces DNA damage and modulates epigenetic effectors in distant bystander tissue in vivo.
Koturbash I, Rugo RE, Hendricks CA, Loree J, Thibault B, Kutanzi K, Pogribny I, Yanch JC, Engelward BP, Kovalchuk O
Oncogene 2006 Jul 20;25(31):4267-75
Oncogene 2006 Jul 20;25(31):4267-75
Effect of long-term tamoxifen exposure on genotoxic and epigenetic changes in rat liver: implications for tamoxifen-induced hepatocarcinogenesis.
Tryndyak VP, Muskhelishvili L, Kovalchuk O, Rodriguez-Juarez R, Montgomery B, Churchwell MI, Ross SA, Beland FA, Pogribny IP
Carcinogenesis 2006 Aug;27(8):1713-20
Carcinogenesis 2006 Aug;27(8):1713-20
Fractionated low-dose radiation exposure leads to accumulation of DNA damage and profound alterations in DNA and histone methylation in the murine thymus.
Pogribny I, Koturbash I, Tryndyak V, Hudson D, Stevenson SM, Sedelnikova O, Bonner W, Kovalchuk O
Molecular cancer research : MCR 2005 Oct;3(10):553-61
Molecular cancer research : MCR 2005 Oct;3(10):553-61
The human DNA methyltransferases (DNMTs) 1, 3a and 3b: coordinate mRNA expression in normal tissues and overexpression in tumors.
Robertson KD, Uzvolgyi E, Liang G, Talmadge C, Sumegi J, Gonzales FA, Jones PA
Nucleic acids research 1999 Jun 1;27(11):2291-8
Nucleic acids research 1999 Jun 1;27(11):2291-8
Cloning, expression and chromosome locations of the human DNMT3 gene family.
Xie S, Wang Z, Okano M, Nogami M, Li Y, He WW, Okumura K, Li E
Gene 1999 Aug 5;236(1):87-95
Gene 1999 Aug 5;236(1):87-95
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