PAB12434

antibody from Abnova Corporation

Targeting: ERN1 IRE1, IRE1P

Western blot (Supportive data in Antibodypedia)

Antibody Data

Product number

PAB12434

Provider

Abnova Corporation

Proper citation

Abnova Corporation Cat#PAB12434, RRID:AB_10551086

Product name

ERN1 polyclonal antibody

Antibody type

Polyclonal

Description

Rabbit polyclonal antibody raised against synthetic peptide of ERN1.

Storage

Store at -20°C or -80°C.Aliquot to avoid repeated freezing and thawing.

References

Submitted references

Regulation of insulin biosynthesis in pancreatic beta cells by an endoplasmic reticulum-resident protein kinase IRE1.

Lipson KL, Fonseca SG, Ishigaki S, Nguyen LX, Foss E, Bortell R, Rossini AA, Urano F
Cell metabolism 2006 Sep;4(3):245-54

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WFS1 is a novel component of the unfolded protein response and maintains homeostasis of the endoplasmic reticulum in pancreatic beta-cells.

Fonseca SG, Fukuma M, Lipson KL, Nguyen LX, Allen JR, Oka Y, Urano F
The Journal of biological chemistry 2005 Nov 25;280(47):39609-15

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Fluoride induces endoplasmic reticulum stress in ameloblasts responsible for dental enamel formation.

Kubota K, Lee DH, Tsuchiya M, Young CS, Everett ET, Martinez-Mier EA, Snead ML, Nguyen L, Urano F, Bartlett JD
The Journal of biological chemistry 2005 Jun 17;280(24):23194-202

Western blot

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

Western blot analysis of ERN1 using ERN1 polyclonal antibody (Cat # PAB12434). Lane 1 : COS-7 untransfected, Lane 2 : COS-7 expressing wild-type ERN1, Lane 3 : COS-7 expressing kinase-dead ERN1.