Antibody data
- Antibody Data
- Antigen structure
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- Product number
- APR02986G - Provider product page
- Provider
- Leading Biology
- Product name
- ERN1 / IRE1 Antibody (C-Terminus)
- Antibody type
- Polyclonal
- Description
- Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto- activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Storage
- Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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